CN105012185A - Cosmetic and application of perilla extract in cosmetic as transdermal penetration enhancer - Google Patents
Cosmetic and application of perilla extract in cosmetic as transdermal penetration enhancer Download PDFInfo
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- CN105012185A CN105012185A CN201510451615.0A CN201510451615A CN105012185A CN 105012185 A CN105012185 A CN 105012185A CN 201510451615 A CN201510451615 A CN 201510451615A CN 105012185 A CN105012185 A CN 105012185A
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Abstract
The invention relates to a cosmetic and an application of a perilla extract in the cosmetic as a transdermal penetration enhancer. The cosmetic provided by the invention contains the perilla extract and a functional component, wherein the perilla extract is a perilla root, stem or leaf extract; the functional component comprises a deep-sea seaweed extract; and the deep-sea alga extract comprises an austria seaweed extract, a light black seaweed extract or a fucus serratus extract. The perilla extract is applied to the cosmetic as the transdermal penetration enhancer, so that absorption of the functional component in the cosmetic can be significantly promoted, so that the functional component in the cosmetic can be relatively well absorbed by the skin; and relatively good efficacies of the skin for moisturizing, replenishing water and locking water are promoted.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of cosmetics and Folium perillae extract as the purposes of transdermal penetration enhancer in cosmetics.
Background technology
Transdermal penetration enhancer refers to the material that can promote that the functional component in cosmetics permeates and absorbs on skin.Existing transdermal penetration enhancer mainly in medical application comparatively extensive, with field of medicaments unlike, functional component in cosmetics does not need to enter people's body-internal-circulation through skin, such as, sun-proof function composition only need rest on skin surface and play its effect, the white-skinned face function composition basal layer be present in epidermis plays its effect, and senile-resistant efficacy composition is present in the skin corium of skin and plays its effect.In order to utilize the functional component in cosmetics better, various transdermal penetration enhancer is used in cosmetics, and wherein, most representational synthetic transdermal penetration enhancer is laurocapram.At present, some natural percutaneous penetration enhancer are also used gradually, such as Mentholum, Oleum Eucalypti etc.
Folium perillae extract, as a kind of natural plant extracts, contains the volatile oil such as abundant perillaldehyde, perilla alcohol, menthone, menthol, eugenol and ergomaketon.At present, propose Folium perillae extract there are no report and can be used as transdermal penetration enhancer, more without report, it can have transdermal enhancing effect to which material.
Deep sea algae is a kind of Sargassaceae species containing enriching trehalose, trehalose is with 1 by two glucopyranose molecules, the disaccharide compound that 1 glycosidic bond links, be called α-D-glycopyranosyl-α-D-glycopyranoside (α-D-glucopyranosyl-α-D-glucopyranoside), molecular formula is C
12o
22h
112H
2o.
The chemical property of trehalose is highly stable, and have the effects such as moisturizing, sun-proof, anti-ultraviolet, Chang Zuowei wetting agent, skin detergents and ultraviolet absorber are applied in the cosmetics of super quality.Recently, Japanese Scientists also finds that trehalose has the effect suppressing old people's body odor, can be used for having the cosmetics except body odor effect.
Summary of the invention
the problem that invention will solve
But, functional component in cosmetics such as deep sea algae also exists the problem being difficult to Transdermal absorption in use, in order to solve this problem, the present invention uses natural Folium perillae extract as transdermal enhancer, promotes the Transdermal absorption of the functional component such as deep sea algae in cosmetics etc.
for the scheme of dealing with problems
The present invention is as described below.
1. cosmetics, containing Folium perillae extract and functional component.
2. the cosmetics according to item 1, wherein, described Folium perillae extract is Folium Perillae root, stem or leaf extract.
3. the cosmetics according to item 1 or 2, wherein, based on the gross weight of described cosmetics, the content of described Folium perillae extract is 0.1 ~ 5%, is preferably 1 ~ 3%, is more preferably 2%.
4. the cosmetics according to any one of item 1 to 3, wherein, described functional component comprises deep sea algae extract, and described deep sea algae extract comprises Ovshinsky Sargassum extract, light black huge Sargassum extract or Fucus Vesiculosus extract.
5. the cosmetics according to item 4, wherein, the molecular weight of described deep sea algae extract is less than 1000 dalton.
6. the cosmetics according to any one of item 1 to 5, wherein, described cosmetics are also containing antiseptic, wetting agent and/or water.
7. Folium perillae extract is as the purposes of transdermal penetration enhancer in cosmetics.
8. the purposes according to item 7, wherein, described Folium perillae extract is Folium Perillae root, stem or leaf extract.
9. the purposes according to item 7 or 8, wherein, described cosmetics contain functional component, described functional component comprises deep sea algae extract, described deep sea algae comprises Ovshinsky Sargassum extract, light black huge Sargassum extract or Fucus Vesiculosus extract, and the molecular weight of described deep sea algae extract is less than 1000 dalton.
10. the preparation method of the cosmetics according to any one of item 1 to 6, wherein, by above-mentioned each component mixing, stirs.
the effect of invention
In the present invention, be used in cosmetics by using Folium perillae extract as transdermal enhancer, can promote the absorption of the functional component in cosmetics significantly, thus skin can absorb the functional component in cosmetics better, impel skin to have the effects such as better moisturizing, moisturizing and lock water.
In addition, Folium perillae extract belongs to natural extract, in safety and mildness, also have some superiority.
In addition, Folium perillae extract contains terpenoid, such as perilla alcohol, perillaldehyde, menthone, menthol and ergomaketon etc., and thus, Folium perillae extract not only has transdermal transdermal enhancing effect, also has certain antisepsis.
Accompanying drawing explanation
Fig. 1 is that Folium perillae extract promotes the graphic of Ovshinsky Sargassum extract absorption as the transdermal enhancer in cosmetics;
Fig. 2 is that Folium perillae extract promotes the graphic of light black huge Sargassum extract absorption as the transdermal enhancer in cosmetics; And
Fig. 3 is that Folium perillae extract promotes the graphic of Fucus Vesiculosus extract absorption as the transdermal enhancer in cosmetics.
Detailed description of the invention
Cosmetics of the present invention contain Folium perillae extract and functional component.
As the Folium perillae extract used in the present invention, have no particular limits, can commercially available prod be used, such as, the Folium perillae extract that the vigorous and graceful company limited (ICHIMARU PHACOS.Co.Ltd.) of a Japanese ball self-heating manufactures can be listed; Also the Folium perillae extract obtained by known method can be used, as the method preparing Folium perillae extract, there is no particular limitation, such as, the root of Folium Perillae, stem or leaf can be dissolved in organic solvent (such as, butanediol) in, by processes such as squeezing, extraction and filtrations, obtain Folium perillae extract.
In cosmetics of the present invention, based on the gross weight of described cosmetics, the content of described Folium perillae extract is 0.1 ~ 5%, if the content of described Folium perillae extract is less than 0.1%, then can concentration too low, DeGrain; If the content of described Folium perillae extract is greater than 5%, moistening effect declines to some extent, and production cost increases, and is uneconomic.The content of described Folium perillae extract is preferably 1 ~ 3%, is more preferably 2%.
In the present invention, described Folium perillae extract is that Folium perillae extract contains terpenoid as the mechanism of transdermal penetration enhancer, such as perilla alcohol, perillaldehyde, menthone, menthol and ergomaketon etc., and these terpenoids have transdermal transdermal enhancing effect.In addition, Folium perillae extract also has certain antisepsis.
Functional component in cosmetics of the present invention can comprise deep sea algae extract, as deep sea algae extract, include but not limited to Ovshinsky Sargassum extract (KANEHIDE GROUP.Co.Ltd manufactures), light black huge Sargassum extract (GREENTECH S.A. manufactures) or Fucus Vesiculosus extract (LESSONIA manufactures, trade name: FUCUS GLYCOLIC EXTRACT S).
Cosmetics of the present invention can also containing other composition being generally used for cosmetic field, such as antiseptic, wetting agent and/or water etc.Described antiseptic includes but not limited to phenoxyethanol, methyl parahydroxybenzoate or benzyl alcohol etc., and described wetting agent includes but not limited to glycerol, propylene glycol or butanediol etc.
Cosmetics of the present invention can such as be prepared in accordance with the following methods: optional water and wetting agent are joined in container and mix, be heated with stirring to 75 ~ 80 DEG C, then heating is stopped, stirring is cooled to 35 ~ 40 DEG C, then, add Folium perillae extract, functional component and optional antiseptic successively, fully stir, obtain cosmetics of the present invention.
On the other hand, the present invention also provides Folium perillae extract as the purposes of transdermal penetration enhancer in cosmetics, especially as transdermal penetration enhancer containing the purposes in the cosmetics of deep sea algae.
Folium perillae extract as transdermal penetration enhancer can promote the absorption of the functional component in cosmetics, and skin can be enable to absorb functional component better, impels skin to have the effects such as better moisturizing, moisturizing and lock water.
Below provide embodiments of the invention.It should be noted that, these embodiments are only illustrative, the invention is not restricted to these embodiments." % " that use in embodiment represents % by weight in case of no particular description.
Embodiment 1 ~ 4
According to the percentage by weight shown in table 1, by water (other each component addition sum of the addition=100%-of water), glycerol and propylene glycol join in reaction vessel and mix, be heated with stirring to 80 DEG C, stop heating, stirring at normal temperature is cooled to 40 DEG C, then Folium perillae extract (ICHIMARU PHACOS.Co.Ltd. manufactures) is added, Ovshinsky Sargassum extract (KANEHIDE GROUP.Co.Ltd manufactures) and phenoxyethanol, and by the moisturizing to 100% of above-mentioned solution (because temperature in operating process raises, water volatilizees, therefore moisturizing to 100% further), room temperature fully stirs 30min, obtain the cosmetics of embodiment 1 ~ 4.
Comparative example 1
According to the percentage by weight shown in table 1, except not adding except Folium perillae extract, being prepared similarly to Example 1, obtaining the cosmetics of comparative example 1.
Table 1
Evaluate
1. tester
Tester's age and Sex distribution: tester is distributed between 20 ~ 30 years old at the age, M-F is 1:3, adds up to total number of persons to be 100 people.After tester takes to enter one's name voluntarily, random choose obtains.
2. test instrunment
Skin CK tester (German CK company skin moisture tester CM825) is used to test the moisture of skin.
3. method of testing
Upper arm first cleans up by tester, to be tested in thermostatic constant wet chamber etc. after having cleaned, waiting time is 30min, the upper arm choosing tester carries out moisture measurement, fixedly choose upper arm 3 pieces of test zones, scope of smearing uses the chase of 3cm × 3cm to delimit, and after measuring its blank value moisture, tests after the cosmetics using liquid-transfering gun to pipette 0.25mL embodiment 1 ~ 4 and comparative example 1 carry out uniform application.Testing total duration is 90min, at interval of 10min test once.After testing, carry out moisture difference (the blank content of moisture difference=moisture measurement content-moisture) average analysis to all test datas, as shown in Figure 1, in FIG, AU is moisture electric conductive unit to result, and min is unit of time.
As seen from Figure 1, in the ratio of not adding Folium perillae extract comparatively 1, moisture of skin increment is on the low side, but, at interpolation Folium perillae extract as in the embodiment 1 ~ 4 of transdermal penetration enhancer, moisture of skin increment is obviously higher, and as can be seen here, Folium perillae extract has obvious transdermal enhancing effect to Ovshinsky Sargassum extract.
In addition, be it can also be seen that by Fig. 1, the content that the transdermal enhancing effect of Folium perillae extract to Ovshinsky Sargassum extract presents along with Folium perillae extract increases, the trend that skin moisture content increases gradually, and when the content of Folium perillae extract is 2.0%, moisture increment is the highest.But when the content of Folium perillae extract is increased to 5.0%, short saturating effect declines on the contrary to some extent.
In addition, along with the increase of time, short saturating effect tends to balance gradually, and when tested when 70min, short saturating effect reaches balance.
Embodiment 5 ~ 8
According to the percentage by weight shown in table 2, by water (other each component addition sum of the addition=100%-of water), glycerol and propylene glycol join in reaction vessel and mix, be heated with stirring to 80 DEG C, stop heating, stirring at normal temperature is cooled to 40 DEG C, then Folium perillae extract (ICHIMARU PHACOS.Co.Ltd. manufactures) is added, light black huge Sargassum extract (GREENTECH S.A. manufactures) and phenoxyethanol, and by the moisturizing to 100% of above-mentioned solution (because temperature in operating process raises, water volatilizees, therefore moisturizing to 100% further), room temperature fully stirs 30min, obtain the cosmetics of embodiment 5 ~ 8.
Comparative example 2
According to the percentage by weight shown in table 2, except not adding except Folium perillae extract, being prepared similarly to Example 5, obtaining the cosmetics of comparative example 2.
Table 2
Use the tester identical with embodiment 1, test instrunment and the cosmetics of method of testing to embodiment 5 ~ 8 and comparative example 2 to carry out test evaluation, test result as shown in Figure 2, the abscissa in Fig. 2 and vertical coordinate and Fig. 1 synonym.
As seen from Figure 2, in the ratio of not adding Folium perillae extract comparatively 2, moisture of skin increment is on the low side, but, at interpolation Folium perillae extract as in the embodiment 5 ~ 8 of transdermal penetration enhancer, moisture of skin increment is obviously higher, and as can be seen here, Folium perillae extract has obvious transdermal enhancing effect to light black huge Sargassum extract.
In addition, be it can also be seen that by Fig. 2, the content that the transdermal enhancing effect of Folium perillae extract to light black huge Sargassum extract presents along with Folium perillae extract increases, and skin moisture content increases gradually, and when the content of Folium perillae extract is 2.0%, moisture increment is the highest.But when the content of Folium perillae extract is increased to 5.0%, short saturating effect declines on the contrary to some extent.
In addition, along with the increase of time, short saturating effect tends to balance gradually, and when tested when 60min, short saturating effect reaches balance.
Embodiment 9 ~ 12
According to the percentage by weight shown in table 3, by water (other each component addition sum of the addition=100%-of water), glycerol and propylene glycol join in reaction vessel and mix, be heated with stirring to 80 DEG C, stop heating, stirring at normal temperature is cooled to 40 DEG C, then Folium perillae extract (ICHIMARU PHACOS.Co.Ltd. manufactures) is added, Fucus Vesiculosus extract (LESSONIA manufacture) and phenoxyethanol, and by the moisturizing to 100% of above-mentioned solution (because temperature in operating process raises, water volatilizees, therefore moisturizing to 100% further), room temperature fully stirs 30min, obtain the cosmetics of embodiment 9 ~ 12.
Comparative example 3
According to the percentage by weight shown in table 3, except not adding except Folium perillae extract, being prepared similarly to Example 9, obtaining the cosmetics of comparative example 3.
Table 3
Use the tester identical with embodiment 1, test instrunment and the cosmetics of method of testing to embodiment 9 ~ 12 and comparative example 3 to carry out test evaluation, test result as shown in Figure 3, the abscissa in Fig. 3 and vertical coordinate and Fig. 1 synonym.
As seen from Figure 3, in the ratio of not adding Folium perillae extract comparatively 3, moisture of skin increment is on the low side, but, at interpolation Folium perillae extract as in the embodiment 9 ~ 12 of transdermal penetration enhancer, moisture of skin increment is obviously higher, and as can be seen here, Folium perillae extract has obvious transdermal enhancing effect to Fucus Vesiculosus extract.
In addition, be it can also be seen that by Fig. 3, the content that the transdermal enhancing effect of Folium perillae extract to Fucus Vesiculosus extract presents along with Folium perillae extract increases, and skin moisture content increases gradually, and when the content of Folium perillae extract is 2.0%, moisture increment is the highest.But when the content of Folium perillae extract is increased to 5.0%, short saturating effect declines on the contrary to some extent.
In addition, along with the increase of time, short saturating effect tends to balance gradually, and when tested when 60min, short saturating effect reaches balance.
Claims (10)
1. cosmetics, is characterized in that, containing Folium perillae extract and functional component.
2. cosmetics according to claim 1, is characterized in that, described Folium perillae extract is Folium Perillae root, stem or leaf extract.
3. cosmetics according to claim 1 and 2, is characterized in that, based on the gross weight of described cosmetics, the content of described Folium perillae extract is 0.1 ~ 5%, are preferably 1 ~ 3%, are more preferably 2%.
4. cosmetics according to any one of claim 1 to 3, is characterized in that, described functional component comprises deep sea algae extract, and described deep sea algae extract comprises Ovshinsky Sargassum extract, light black huge Sargassum extract or Fucus Vesiculosus extract.
5. cosmetics according to claim 4, is characterized in that, the molecular weight of described deep sea algae extract is less than 1000 dalton.
6. cosmetics according to any one of claim 1 to 5, is characterized in that, described cosmetics are also containing antiseptic, wetting agent and/or water.
7. Folium perillae extract is as the purposes of transdermal penetration enhancer in cosmetics.
8. purposes according to claim 7, is characterized in that, described Folium perillae extract is Folium Perillae root, stem or leaf extract.
9. the purposes according to claim 7 or 8, it is characterized in that, described cosmetics contain functional component, described functional component comprises deep sea algae extract, described deep sea algae comprises Ovshinsky Sargassum extract, light black huge Sargassum extract or Fucus Vesiculosus extract, and the molecular weight of described deep sea algae extract is less than 1000 dalton.
10. the preparation method of cosmetics according to any one of claim 1 to 6, is characterized in that, by each component mixing, stirs.
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| CN106726741A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of medical cosmetology skin penetration enhancer containing natural plant essence |
| CN107213048A (en) * | 2016-12-23 | 2017-09-29 | 翁绍瑀 | A kind of purple perilla skin care item and preparation method thereof |
| CN108324667A (en) * | 2018-04-09 | 2018-07-27 | 广州赛莱拉干细胞科技股份有限公司 | Composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract |
| CN108403535A (en) * | 2018-06-08 | 2018-08-17 | 上海家化联合股份有限公司 | Purple perilla tender leaf extract and its application |
| CN109223666A (en) * | 2018-12-04 | 2019-01-18 | 范承功 | A kind of plant extracts with transdermal enhancing effect and its application in skin care item |
| WO2020093393A1 (en) | 2018-11-06 | 2020-05-14 | 万华化学集团股份有限公司 | Aqueous polyurethane functional mask substrate and application thereof |
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| CN106399437A (en) * | 2016-09-07 | 2017-02-15 | 深圳凯联龟业有限公司 | Preparation method of mauremys mutica polypeptide and mauremys mutica polypeptide facial mask |
| CN106399437B (en) * | 2016-09-07 | 2020-02-14 | 深圳凯联龟业有限公司 | Preparation method of small water turtle polypeptide and small water turtle polypeptide mask |
| CN106726703A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of cosmetics based on Transdermal absorption |
| CN106726741A (en) * | 2016-11-17 | 2017-05-31 | 徐慧婷 | A kind of medical cosmetology skin penetration enhancer containing natural plant essence |
| CN107213048A (en) * | 2016-12-23 | 2017-09-29 | 翁绍瑀 | A kind of purple perilla skin care item and preparation method thereof |
| CN108324667A (en) * | 2018-04-09 | 2018-07-27 | 广州赛莱拉干细胞科技股份有限公司 | Composition and anti-aging Skin whitening care cosmetics containing light black huge marine algae extract |
| CN108403535A (en) * | 2018-06-08 | 2018-08-17 | 上海家化联合股份有限公司 | Purple perilla tender leaf extract and its application |
| WO2020093393A1 (en) | 2018-11-06 | 2020-05-14 | 万华化学集团股份有限公司 | Aqueous polyurethane functional mask substrate and application thereof |
| US11964032B2 (en) | 2018-11-06 | 2024-04-23 | Wanhua Chemical Group Co., Ltd. | Aqueous polyurethane functional mask substrate and application thereof |
| CN109223666A (en) * | 2018-12-04 | 2019-01-18 | 范承功 | A kind of plant extracts with transdermal enhancing effect and its application in skin care item |
| CN109223666B (en) * | 2018-12-04 | 2021-05-25 | 施莱新研(杭州)生物科技有限公司 | Plant extract composition and application thereof in skin care products |
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Effective date of registration: 20210608 Address after: No.23 Xianke Er Road, Huadong Town, Huadu District, Guangzhou City, Guangdong Province 510800 Patentee after: GUANGZHOU KENENG COSMETIC RESEARCH Co.,Ltd. Patentee after: GUANGDONG DANZ GROUP Co.,Ltd. Address before: No.23, Xianke 2nd Road, Huadong Town, Huadu District, Guangzhou, Guangdong 510000 Patentee before: GUANGZHOU KENENG COSMETIC RESEARCH Co.,Ltd. Patentee before: GUANGZHOU BAIYUN LIANJIA FINE CHEMICAL FACTORY Patentee before: GUANGDONG DANZ GROUP Co.,Ltd. |