CN108721153A - A kind of moisturizing combination and preparation method thereof containing starfish branch tube algae extract - Google Patents
A kind of moisturizing combination and preparation method thereof containing starfish branch tube algae extract Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/602—Glycosides, e.g. rutin
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
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- A61Q19/08—Anti-ageing preparations
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Abstract
The moisturizing combination and preparation method thereof containing starfish branch tube algae extract that the invention discloses a kind of, is related to technical field of skin care, solves the technical problem of existing moisturizer moistening effect difference.It is characterized in that:It includes component A and B component, and the component A includes the ingredient of following parts by weight:2.12-13 parts of Sodium Hyaluronate mixture;2-7 parts of carbohydrate isomer;6-15 parts of alcohols moisturizer;0.01-0.2 parts of Sensiva SC50;15-25 parts of deionized water;The B component includes the ingredient of following parts by weight:20-30 parts of starfish branch tube algae extract;10-20 parts of 1,3- propylene glycol.It can promote the expression of aquaporin by using Sodium Hyaluronate moisturizing water storage, carbohydrate isomer and polyquaternium -51 compounding, starfish branch tube algae extract forms fine and close Adelomorphic protecting, have the advantages that outer layer moisturizing, internal layer water lock, layer by layer moisturizing, skin from inside to outside water moisten it is glossy.
Description
Technical field
The present invention relates to technical field of skin care, more specifically, it relates to a kind of containing starfish branch tube algae extract
Moisturizing combination and preparation method thereof.
Background technology
In face of the air of increasingly environmental pollution, our skin of face is exposed in the air of pollution, aggravates skin aging,
Quickly and the rhythm of life full of pressure and irregular living habit along with modern.Especially Internet era removes
Other than life is irregular, average people are more than daily 8 hours or more using the electronic product time, and light pollution also can let us
Skin increasingly accelerates aging.
A kind of moisturizing without preservative is disclosed in the Chinese invention patent application No. is CN201611000547.7
Skin toner water composition, including following components in percentage by weight:Plant extracts 0.05~10%;Moisturizer 1~20%;Xin Gan
Alcohol 0.1~5%;Iso-octyl glycerine 0.1~5%;Deionized water adds to 100%;A kind of moisturizing without preservative is refreshing
Skin water composition does not contain《Cosmetics safety technical specification》Any preservative of (2015) defined.Moisturizer be glycerine,
It is 1,3- propylene glycol, 1,2- pentanediols, butanediol, Xylitol-based glucoside, xylitol, anhydro xylitol, biological carbohydrate gum -1, transparent
The composition of matter acid sodium, three kinds or more in glucan.
Above-mentioned moisturizing toner mainly can adsorb moisture in air by common moisturizing ingredient, glycerine such as glycerine, alcohols
To give skin moisturizing, glycerine can also draw corium moisture and enable skin dehydration when skin is too dry, and alcohols moisturizer is readily volatilized, smear
When also only have a small amount of moisturizing ingredient play moisture-keeping function, moreover, moisturizing persistence is poor, it is, therefore, desirable to provide a kind of new scheme
To solve the above problems.
Invention content
In view of the deficienciess of the prior art, the purpose of the present invention one is that providing one kind containing starfish branch tube algae extract
Moisturizing combination, the expression of aquaporin can be promoted by using Sodium Hyaluronate moisturizing water storage, carbohydrate isomer,
Starfish branch tube algae extract forms fine and close Adelomorphic protecting, solves above-mentioned technical problem, with outer layer moisturizing, internal layer water lock,
Water moistens glossy advantage from inside to outside for moisturizing layer by layer, skin.
To achieve the above object one, the present invention provides following technical solutions:
A kind of moisturizing combination containing starfish branch tube algae extract, including component A and B component, the component A include following weight
The ingredient of number:
2.12-13 parts of Sodium Hyaluronate mixture;
2-7 parts of carbohydrate isomer;
6-15 parts of alcohols moisturizer;
0.01-0.2 parts of Sensiva SC50;
15-25 parts of deionized water;
The B component includes the ingredient of following parts by weight:
20-30 parts of starfish branch tube algae extract;
10-20 parts of 1,3- propylene glycol.
By using above-mentioned technical proposal, hyaluronic acid (HA) also known as Hyaluronic Acid, sodium hyaluronate.Commercial product is mostly its sodium
Salt form, referred to as Sodium Hyaluronate.It is that line style straight-chain macromolecule sticks polysaccharide, by glucuronic acid and N- acetamido glucoses
The dissacharide units of sugar composition repeat to be formed by connecting.Carboxyl and other polar groups in molecule can be combined to form hydrogen bond with water, 1 gram
Hyaluronic acid can lock the water of 1000 times of its weight, under low relative humidity environment, hygroscopic capacity highest;Under high relative humidity conditions,
Hygroscopic capacity is minimum.Intelligence is adjusted, and ensures skin water profit.
On the one hand starfish branch tube algae (CLADOSIPHON NOVAE-CALEDONIAE) extract can coordinate hyaluronic acid
Sodium mixture forms fine and close Adelomorphic protecting, long-time moisturizing in skin surface.Maintenance stratum corneum barrier, avoid harmful substance or
Atmosphere pollution granular absorption enters in pore.On the other hand, starfish branch tube algae extract has inhibiting effect to prolyl endopeptidase,
It is beneficial to adjusting angiotensins, neurotensin, illustrate have the function of releiving, in conjunction with its inoxidizability, can be used for skin
Skin is raised;And can effectively inhibit the decomposition of hyaluronic acid, enhance skin moisturization.
On the one hand alcohols moisturizer has the function of moisturizing, on the other hand as the solvent of Sodium Hyaluronate, solution rate
Soon, dispersion effect is good.
Further preferably, the Sodium Hyaluronate mixture includes the ingredient of following parts by weight:
0.02-2 parts of Sodium Hyaluronate cross-linked polymer;
1-5 parts of Sodium Hyaluronate;
1-3 parts of acetylation Sodium Hyaluronate;
Hydrolyze 0.1-3 parts of Sodium Hyaluronate.
By using above-mentioned technical proposal, the molecular weight of Sodium Hyaluronate cross-linked polymer is more than 1,800,000, in skin surface
Fine and close Adelomorphic protecting, confrontation UV/ pollutions are formed, moisturizing for 24 hours, active matter sustained release are up to;The molecular weight of Sodium Hyaluronate exists
Between 100-180 ten thousand, skin surface water lock, moisturizing, cutin-softening layer are acted on;The molecular weight of acetylation Sodium Hyaluronate is in 1-
Between 1000000, there is suction-operated, be firmly adsorbed on cutin layer surface, damaged Stratum Corneum is repaired in double water conservation;It hydrolyzes transparent
Matter acid sodium molecule amount is less than 10,000, can rapid transdermal absorb, through epidermis and skin corium, deep moisturizing repair flesh bottom
Shield.
Further preferably, the B component further includes 10-20 parts of copper victory peptide.
By using above-mentioned technical proposal, copper is to maintain physical function required micro- (2 milligrams of daily demand),
Function is many and complicated, is the element that various cytase effects need.In using for skin histology, there is anti-oxidant, promotion
Collagen Proliferation, the function of assisting wound healing.Inventor has found that copper molecule has smoothing wrinkle effect, mainly compound by Amino acid
The carrier of object (victory peptide peptide), makes that there is the bivalent cupric ion ingredient of biochemical effects to enter cell, plays physiological function.Copper
It is bonded amino acid GHK-CU, is a kind of compound being made of three amino acid and a copper ion, this indigo plant copper victory peptide can
To effectively facilitate the manufacture of collagen (Collagen) and elastic (Elastin) albumen, increase angiogenic growth and anti-oxidant energy
Power, and glucose polyamine (GAGs) is stimulated to generate, help skin to reply the instinctive ability of self-repair.It is extracted with starfish branch tube algae
Synergistic after object is used in compounding, enhancing skin is anti-oxidant and repair ability.
Further preferably, the component A further includes 3-5 parts of polyquaterniums -51.
By using above-mentioned technical proposal, polyquaternium -51 has antipollution, mitigates UV pressure, mitigate stimulation, is anti-
Imperial drying, the effect for inhibiting bacterium attachment, and carbohydrate isomer and polyquaternium -51, which are used in compounding, can promote water logical
The expression of road albumen (aquaporin-3), while the pore that compacts.
Further preferably, the B component further includes 30-40 parts of glycosylglycerol.
By using above-mentioned technical proposal, glycosylglycerol is that one kind is combined with glucose molecule with glycosidic bond by glycerine
Substance has moisturizing and oxidation resistant effect, synergistic after being used cooperatively with copper victory peptide, is obviously improved antioxidant effect.
Further preferably, the alcohols moisturizer includes 1-5 parts of 1,2- pentanediols and 5-10 parts of 1,3-PD.
By using above-mentioned technical proposal, the solvent of 1,2- pentanediol and 1,3-PD as Sodium Hyaluronate, dissolving
Speed is fast, and dispersion effect is good.
Further preferably, the component A includes the ingredient of following parts by weight:
0.02-2 parts of Sodium Hyaluronate cross-linked polymer;
1-5 parts of Sodium Hyaluronate;
1-3 parts of acetylation Sodium Hyaluronate;
Hydrolyze 0.1-3 parts of Sodium Hyaluronate;
- 513-5 parts of polyquaternium;
2-7 parts of carbohydrate isomer;
1-5 parts of 1,2- pentanediols;
5-10 parts of 1,3- propylene glycol;
0.01-0.2 parts of Sensiva SC50;
15-25 parts of deionized water;
The B component includes the ingredient of following parts by weight:
20-30 parts of starfish branch tube algae extract;
10-20 parts of 1,3- propylene glycol;
Copper wins 10-20 parts of peptide;
30-40 parts of glycosylglycerol.
By using above-mentioned technical proposal, above-mentioned each component is worked in coordination, and the moistening effect of combination is made to be obviously improved, and is ensured
Skin water moistens, and enhances that skin is anti-oxidant and repair ability.
The purpose of the present invention two is to provide a kind of preparation method of the moisturizing combination containing starfish branch tube algae extract, adopt
The moisturizing combination prepared with this method with outer layer moisturizing, internal layer water lock, layer by layer moisturizing, skin from inside to outside water moisten it is glossy excellent
Point.
To achieve the above object two, the present invention provides following technical solutions:
A kind of preparation method of the moisturizing combination containing starfish branch tube algae extract, includes the following steps:
Sodium Hyaluronate mixture and 1,3-PD are pre-mixed by step 1, and dispersion is impregnated 3 hours, and mixed liquor is obtained;
Step 2 is stirred dispersion until complete clear is without undissolved particle with blender to mixed liquor;
Step 3 stirs evenly the other compositions addition in component A, then by 100 mesh filter screen filtrations, obtained filtrate is
A phases;
Step 4 stirs evenly after mixing starfish branch tube algae extract and 1,3-PD, adds other in B component
Ingredient is uniformly dispersed, and obtains B phases;
Step 5 mixes A phases and B uniformly, discharging.
Moisturizing combination in the present invention is suitable for the skin care item such as facial mask, lotion, cream, frost, essence, water, and dosage is preferably protected
The 10-30% of skin product weight.
In conclusion compared with prior art, the invention has the advantages that:
(1) starfish branch tube algae extract has inhibiting effect to prolyl endopeptidase, to adjusting angiotensins, nervous being known as
Benefit has the function of releiving, and in conjunction with its inoxidizability, and can effectively inhibit the decomposition of hyaluronic acid, enhances skin moisture-keeping
Effect;
(2) copper victory peptide and after starfish branch tube algae extract is used in compounding, synergistic, enhancing skin is anti-oxidant and repair ability;
(3) carbohydrate isomer and polyquaternium -51 are used in compounding the expression that can promote aquaporin, while the hair that compacts
Hole;
(4) glycosylglycerol is a kind of substance combined with glycosidic bond with glucose molecule by glycerine, with moisturizing and anti-oxidant
Effect, it is synergistic after being used cooperatively with copper victory peptide, be obviously improved antioxidant effect.
Specific implementation mode
With reference to embodiment, the present invention will be described in detail.
Embodiment 1:A kind of moisturizing combination containing starfish branch tube algae extract, including component A and B component, component A, B groups
Divide and its corresponding parts by weight are as shown in table 1, and acquisition is made by the steps:
Sodium Hyaluronate mixture and 1,3-PD are pre-mixed by step 1, and dispersion is impregnated 3 hours, and mixed liquor is obtained;
Step 2 is stirred dispersion until complete clear is without undissolved particle, stirring speed with blender to mixed liquor
Spend 300rpm;
Step 3 stirs evenly the other compositions addition in component A, then by 100 mesh filter screen filtrations, obtained filtrate is
A phases;
Step 4 stirs evenly after mixing starfish branch tube algae extract and 1,3-PD, adds other in B component
Ingredient is uniformly dispersed, and obtains B phases;
Step 5 mixes A phases and B uniformly, discharging.
Embodiment 2-8:A kind of moisturizing combination containing starfish branch tube algae extract, difference from example 1 is that,
Component A, B component and its corresponding parts by weight are as shown in table 1.
Component A, B component and its corresponding parts by weight of 1 embodiment 1-8 of table
Embodiment 9-15:A kind of moisturizing combination containing starfish branch tube algae extract, difference from example 1 is that, A groups
Point, B component and its corresponding parts by weight it is as shown in table 2.
Component A, B component and its corresponding parts by weight of 2 embodiment 9-15 of table
Comparative example 1:A kind of moisturizing combination containing starfish branch tube algae extract, by 15 part 1,3- of 25 parts of starfish branch tube algae extracts
After mixed with propylene glycol, 60 parts of deionized waters are added, stir evenly.
Comparative example 2:It is a kind of containing starfish branch tube algae extract moisturizing combination, by 1 part of Sodium Hyaluronate cross-linked polymer,
7 parts of 3 parts of Sodium Hyaluronate, 2 parts of acetylation Sodium Hyaluronate, 1.5 parts of Sodium Hyaluronate of hydrolysis and 1,3-PD premixings, add
Enter 85.5 parts of deionized waters, dispersion is impregnated 3 hours.
Comparative example 3:Moisturizing is prepared using the embodiment 1 in the Chinese invention patent application No. is CN201611000547.7
Skin toner water composition.
Comparative example 4:After 15 parts of copper are won peptide and 65 parts of 1,3-PDs, 20 parts of deionized waters mixing, stir evenly.
Comparative example 5:After 35 parts of glycosylglycerols and 45 parts of 1,3-PDs, 20 parts of deionized waters are mixed, stir evenly
?.
Test moistening effect test
Test specimen:Test specimen 1-15 is used as using the moisturizing combination obtained in embodiment 1-15, using being obtained in comparative example 1-3
Moisturizing combination and moisturizing skin toner water composition sample 1-3 as a contrast.
Test method:Using the instrument and method test in the Chinese invention patent application No. is CN201610039840.8
Volunteer face uses the moisture content of skin after test specimen 1-15 and control sample 1-3.
Test result:As shown in Table 3, moisture content of skin is significantly increased test specimen 1-15 after use, and control sample
Moisture content of skin increase is less after use by 1-3, and after using 1,4,8 hour, the moisture content of skin of test specimen 1-15
It is above control sample 1-3, illustrates that Sodium Hyaluronate mixture, carbohydrate isomer, starfish branch tube algae extract mutually match
It closes and uses, it is synergistic, it is obviously improved the moistening effect of moisturizing combination, and extend moisture preserving time.
The moisture content of skin test result of table 3 test specimen 1-15 and control sample 1-3
Test the experiment of two anti-wrinkle
Test specimen:Test specimen 1-15 is used as using the moisturizing combination obtained in embodiment 1-15, using being obtained in comparative example 1-5
Sample sample 1-5 as a contrast.
Test method:The healthy women crowd case 2000 for randomly selecting 25-40 Sui of areal is used as subject,
Stochastic averagina is divided into 20 groups, and there are symptoms such as microgroove or wrinkles, 1-20 group subjects make the eye circumference skin of subject respectively
With test specimen 1-15 and control sample 1-5, application method:After washing one's face every time with warm water, enough samples are permeated using cotton pads
Moisture saver mask is made, soak is removed after five minutes, twice a day.Subject is recorded to wrinkle before and using eye circumference after two months
The data of line quantity and depth.Give up every group of maximum value and minimum value, it is remaining to take its average value, calculate wrinkle quantity and
The reduction percentage of depth.
Test result:As shown in Table 4, the wrinkle quantity of test specimen 1-15 and wrinkle depth reduce percentage and are all higher than pair
Product 1-5 in the same old way, the wrinkle quantity and wrinkle depth of test specimen 3 reduce the sum that percentage is more than control sample 1 and 2, test sample
The wrinkle quantity and wrinkle depth of product 10 reduce test of the test value more than control sample 4 and 5 that percentage subtracts test specimen 3
The sum of value, synergistic after illustrating that copper victory peptide and starfish branch tube algae extract are used in compounding, enhancing skin is anti-oxidant and repairs energy
Power;Glycosylglycerol has moisturizing and oxidation resistant effect, synergistic after being used cooperatively with copper victory peptide, is obviously improved anti-
Oxidation effectiveness.
The smoothing wrinkle test result of table 4 test specimen 1-15 and control sample 1-5
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-described embodiment,
All technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art
For those of ordinary skill, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (8)
1. a kind of moisturizing combination containing starfish branch tube algae extract, which is characterized in that including component A and B component, the A groups
It point include the ingredient of following parts by weight:
2.12-13 parts of Sodium Hyaluronate mixture;
2-7 parts of carbohydrate isomer;
6-15 parts of alcohols moisturizer;
0.01-0.2 parts of Sensiva SC50;
15-25 parts of deionized water;
The B component includes the ingredient of following parts by weight:
20-30 parts of starfish branch tube algae extract;
10-20 parts of 1,3- propylene glycol.
2. the moisturizing combination according to claim 1 containing starfish branch tube algae extract, which is characterized in that the hyalomitome
Sour sodium mixture includes the ingredient of following parts by weight:
0.02-2 parts of Sodium Hyaluronate cross-linked polymer;
1-5 parts of Sodium Hyaluronate;
1-3 parts of acetylation Sodium Hyaluronate;
Hydrolyze 0.1-3 parts of Sodium Hyaluronate.
3. the moisturizing combination according to claim 1 containing starfish branch tube algae extract, which is characterized in that the B component
It further include 10-20 parts of copper victory peptide.
4. the moisturizing combination according to claim 1 containing starfish branch tube algae extract, which is characterized in that the component A
Further include 3-5 parts of polyquaterniums -51.
5. the moisturizing combination according to claim 3 containing starfish branch tube algae extract, which is characterized in that the B component
It further include 30-40 parts of glycosylglycerol.
6. the moisturizing combination according to claim 1 containing starfish branch tube algae extract, which is characterized in that the alcohols is protected
Humectant includes 1-5 parts of 1,2- pentanediols and 5-10 parts of 1,3- propylene glycol.
7. the moisturizing combination according to claim 1 containing starfish branch tube algae extract, which is characterized in that the component A
Include the ingredient of following parts by weight:
0.02-2 parts of Sodium Hyaluronate cross-linked polymer;
1-5 parts of Sodium Hyaluronate;
1-3 parts of acetylation Sodium Hyaluronate;
Hydrolyze 0.1-3 parts of Sodium Hyaluronate;
- 51 3-5 parts of polyquaternium;
2-7 parts of carbohydrate isomer;
1-5 parts of 1,2- pentanediols;
5-10 parts of 1,3- propylene glycol;
0.01-0.2 parts of Sensiva SC50;
15-25 parts of deionized water;
The B component includes the ingredient of following parts by weight:
20-30 parts of starfish branch tube algae extract;
10-20 parts of 1,3- propylene glycol;
Copper wins 10-20 parts of peptide;
30-40 parts of glycosylglycerol.
8. a kind of preparation method of the moisturizing combination containing starfish branch tube algae extract, which is characterized in that include the following steps:
Sodium Hyaluronate mixture and 1,3-PD are pre-mixed by step 1, and dispersion is impregnated 3 hours, and mixed liquor is obtained;
Step 2 is stirred dispersion until complete clear is without undissolved particle with blender to mixed liquor;
Step 3 stirs evenly the other compositions addition in component A, then by 100 mesh filter screen filtrations, obtained filtrate is
A phases;
Step 4 stirs evenly after mixing starfish branch tube algae extract and 1,3-PD, adds other in B component
Ingredient is uniformly dispersed, and obtains B phases;
Step 5 mixes A phases and B uniformly, discharging.
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Cited By (11)
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CN109223670A (en) * | 2018-10-11 | 2019-01-18 | 广州艾蓓生物科技有限公司 | A kind of moisture-keeping composition and deep moisturizing foundation emulsion |
CN109260097A (en) * | 2018-11-29 | 2019-01-25 | 上海阅容生物医药科技有限公司 | A kind of small molecule sodium hyaluronate invisible face pack |
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CN106265314A (en) * | 2016-08-31 | 2017-01-04 | 广州欧慕生物科技有限公司 | One is applicable to sensitive flesh shaving foam composition and cosmetics thereof and application |
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CN109223670A (en) * | 2018-10-11 | 2019-01-18 | 广州艾蓓生物科技有限公司 | A kind of moisture-keeping composition and deep moisturizing foundation emulsion |
CN109260097B (en) * | 2018-11-29 | 2022-01-04 | 上海阅容生物医药科技有限公司 | Micromolecule hyaluronic acid invisible mask |
CN109260097A (en) * | 2018-11-29 | 2019-01-25 | 上海阅容生物医药科技有限公司 | A kind of small molecule sodium hyaluronate invisible face pack |
CN109260095A (en) * | 2018-11-29 | 2019-01-25 | 上海阅容生物医药科技有限公司 | A kind of small molecule sodium hyaluronate stoste |
CN109568162A (en) * | 2019-01-17 | 2019-04-05 | 浙江康知秀日用品有限公司 | A kind of moisture-keeping composition and its application |
CN112206181A (en) * | 2019-07-09 | 2021-01-12 | 广州凡岛网络科技有限公司 | Moisturizing composition, moisturizing cosmetic and preparation method thereof |
CN111888275A (en) * | 2020-09-15 | 2020-11-06 | 上海百雀羚生物科技有限公司 | Composition and preparation method and application thereof |
CN111991258A (en) * | 2020-10-12 | 2020-11-27 | 上海辉文生物技术股份有限公司 | Skin detoxification and oxidation resistance composition and application thereof |
CN111991258B (en) * | 2020-10-12 | 2022-06-14 | 上海辉文生物技术股份有限公司 | Skin detoxification and oxidation resistance composition and application thereof |
CN112870142A (en) * | 2021-02-07 | 2021-06-01 | 艾后生物科技(上海)有限公司 | Efficient moisturizing essence cream and preparation method thereof |
CN112842985A (en) * | 2021-02-08 | 2021-05-28 | 广州花出见生物科技有限公司 | Moisturizing and repairing composition |
CN115517997A (en) * | 2022-09-27 | 2022-12-27 | 浙江湃肽生物股份有限公司 | Cosmetic composition and preparation method and application thereof |
CN115517997B (en) * | 2022-09-27 | 2024-01-23 | 浙江湃肽生物股份有限公司 | Cosmetic composition, and preparation method and application thereof |
CN115836998A (en) * | 2022-12-27 | 2023-03-24 | 崔修军 | Long-acting moisturizing method for whitening and removing wrinkles |
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