CN105106646A - Medicinal preparation for treating chronic pharyngitis - Google Patents
Medicinal preparation for treating chronic pharyngitis Download PDFInfo
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- CN105106646A CN105106646A CN201510578639.2A CN201510578639A CN105106646A CN 105106646 A CN105106646 A CN 105106646A CN 201510578639 A CN201510578639 A CN 201510578639A CN 105106646 A CN105106646 A CN 105106646A
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Abstract
The invention belongs to the field of Chinese herb preparations, and particularly provides a medicinal preparation for treating chronic pharyngitis. The medicinal preparation is prepared from 20 parts of potentilla kleiniana, 18 parts of talinum paniculatum, 25 parts of cheilanthes chusana, 25 parts of trigonotis peduncularis, 20 parts of lonicera japonica, 28 parts of radix glehniae, 15 parts of radix ranunculi ternate, 15 parts of rehmannia glutinosa, 20 parts of radix scrophulariae, 25 parts of radix salviae miltiorrhizae, 20 parts of juncus effusus, 25 parts of radix polygonati officinalis, 20 parts of radix ophiopogonis, 15 parts of blackberrykiky rhizome, 15 parts of chrysanthemums and 5 parts of liquorice. The medicinal preparation is capable of treating chronic pharyngitis.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of chronic pharyngitis and its preparation method and application.
Background technology
Chronic pharyngitis is under pharynx mucosa, mucosa and adenoid chronic inflammatory disease.Diffusivity pharyngeal inflammation is often a part for upper respiratory tract chronic inflammatory disease; Limitation pharyngeal inflammation mostly then is pharynx lymphoid tissue inflammation.Primary disease is common in clinical, and the course of disease is long, the easy recurrent exerbation of symptom.For this reason, be bursting to and develop the needs that more medicines for the treatment of chronic pharyngitis safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of chronic pharyngitis disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of chronic pharyngitis, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba potentillae kleinianae 20 parts, Herba platantherae minoris 18 parts, Herba Cheilanthes chusane 25 parts, Herba Trigonotidis peduncularis 25 parts, Flos Lonicerae 20 parts, Radix Glehniae 28 parts, Radix Ranunculi Ternati 15 parts, Radix Rehmanniae 15 parts, Radix Scrophulariae 20 parts, Radix Salviae Miltiorrhizae 25 parts, Medulla Junci 20 parts, Rhizoma Polygonati Odorati 25 parts, Radix Ophiopogonis 20 parts, Rhizoma Belamcandae 15 parts, Flos Chrysanthemi 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of chronic pharyngitis, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of chronic pharyngitis, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment chronic pharyngitis medicine being used for the treatment of chronic pharyngitis.
Herba potentillae kleinianae is Rosaceae potentilla plants.Classification system PotentillakleinianaWightetArn., toil, cool.Heat clearing away, removing toxic substances.Control the high heat of infantile convulsion, malaria, cough, laryngalgia, arthralgia chiefly caused by damp pathogen, carbuncle tinea skin ulcer, erysipelas, prurigo, Serpentis, insect bite wound.The present invention is with all herbal medicine.
Herba platantherae minoris is the herb of orchid uvula lip orchid, latin name: Platantheraminor (Miq.) Reichb.F., nourishing YIN and moistening the lung, supplementing QI for promoting the production of body fluid.For cough with blood-flecked phlegm, laryngopharynx swelling and pain, weak after being ill, neurasthenia, seminal emission, dizzy.
Herba Cheilanthes chusane is that Sinopteridaceae vegetable hair axle is cracked rice the herb of Herba pteridii latiusculi.Latin is called Pterismultifdapoir, property mildly bitter flavor; Cold; Nontoxic, control dysentery, urine pain, foot is soft unable, fever with pantalgia, laryngalgia, venom, carbuncle furuncle and phyma scrofula.
Herba Trigonotidis peduncularis, formal name used at school: Trigonotispeduncularis is the plant that Boraginaceae Herba Trigonotidis peduncularis belongs to, and annual herb is high 5 ~ 30 centimetres; Stem is usually from base portion branch, very thin.Cochlear, ellipse or lance-shaped lobule alternate, base portion is narrow, the calm coarse wool of the equal tool in two sides.Spend and be usually born in racemose side, corolla is blue, and inflorescence top is circumvolution shape.4 pieces of tetrahedroid pyrenes.5 ~ June of florescence.Cure mainly phlegm dyspnea, order disease, cataracta etc.The present invention is with all herbal medicine.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that all diseases of throat all belong to fire, chronic pharyngolaryngitis is relevant with fire, Herba potentillae kleinianae of the present invention, Herba platantherae minoris, Herba Cheilanthes chusane, Herba Trigonotidis peduncularis, Flos Lonicerae, Radix Glehniae, Radix Ranunculi Ternati heat-clearing and toxic substances removing, pharynx-clearing throat-benefiting are monarch drug, Radix Rehmanniae, Radix Scrophulariae, Radix Salviae Miltiorrhizae, Medulla Junci, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Belamcandae, Flos Chrysanthemi blood circulation promoting and blood stasis dispelling, nourishing lung yin are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, treatment chronic pharyngitis successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Herba potentillae kleinianae 20g, Herba platantherae minoris 18g, Herba Cheilanthes chusane 25g, Herba Trigonotidis peduncularis 25g, Flos Lonicerae 20g, Radix Glehniae 28g, Radix Ranunculi Ternati 15g, Radix Rehmanniae 15g, Radix Scrophulariae 20g, Radix Salviae Miltiorrhizae 25g, Medulla Junci 20g, Rhizoma Polygonati Odorati 25g, Radix Ophiopogonis 20g, Rhizoma Belamcandae 15g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Herba potentillae kleinianae 20g, Herba platantherae minoris 18g, Herba Cheilanthes chusane 25g, Herba Trigonotidis peduncularis 25g, Flos Lonicerae 20g, Radix Glehniae 28g, Radix Ranunculi Ternati 15g, Radix Rehmanniae 15g, Radix Scrophulariae 20g, Radix Salviae Miltiorrhizae 25g, Medulla Junci 20g, Rhizoma Polygonati Odorati 25g, Radix Ophiopogonis 20g, Rhizoma Belamcandae 15g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Herba potentillae kleinianae 20g, Herba platantherae minoris 18g, Herba Cheilanthes chusane 25g, Herba Trigonotidis peduncularis 25g, Flos Lonicerae 20g, Radix Glehniae 28g, Radix Ranunculi Ternati 15g, Radix Rehmanniae 15g, Radix Scrophulariae 20g, Radix Salviae Miltiorrhizae 25g, Medulla Junci 20g, Rhizoma Polygonati Odorati 25g, Radix Ophiopogonis 20g, Rhizoma Belamcandae 15g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, pharmaceutical preparation treatment chronic pharyngitis of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation chronic pharyngitis case 60 example, 15 ~ 57 years old age.The shortest person of the course of disease 4 months, most elder reaches 3 years.
4.2 diagnostic criterias: (1) medical history: often have acute pharyngitis history of repeated attack, or because of nose ill, long-term mouth breathing, and tobacco and wine are excessive, surrounding is dry, dust and irritative gas pollution etc.(2) symptom: pharyngeal discomfort, or ache or itch or dry sensation, there are burning sensation, sootiness sense, foreign body sensation etc.; Irritable cough, plays firmly expectoration secretions morning, even feel sick.The course of disease more than 2 months, Chang Yin suffers from cold, catch a cold, the reason such as fatigue, polylogia causes outbreak.(3) check: pharyngeal chronic congestion, mucosa is kermesinus, or dendroid is congested; Retropharyneal folliculosis, or lateral pharyngeal band enlargement; Pharynx mucosa hypertrophy is plump, or drying, atrophy, thinning, has secretions to adhere to.Possess above-mentioned symptom and more than 1 or 1 check finding, namely diagnosable.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule one month is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: within treating 1 course for the treatment of, symptom alleviates, within 3 months, clinical symptoms and sign disappear, and more than 2 years without recurrence.Effective: within treating 2 courses for the treatment of, symptom alleviates, within 3 months, clinical symptoms and sign disappear, and more than 1 year without recurrence.If flu, the pharyngeal sense of discomfort time is no more than 10 days.Effective: within treating 2 courses for the treatment of, symptom alleviates, within 3 months, clinical symptoms and part sign disappear, without recurrence in 1 year.Invalid: the rear symptom for the treatment of slightly alleviates or without alleviating, sign is not improved.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 30 | 16 | 12 | 2 | 93.3 |
| Blank group | 30 | 1 | 1 | 28 | 6.7 |
Visible, the medicine that the present invention obtains can safe and effective treatment chronic pharyngitis, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of chronic pharyngitis, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba potentillae kleinianae 20 parts, Herba platantherae minoris 18 parts, Herba Cheilanthes chusane 25 parts, Herba Trigonotidis peduncularis 25 parts, Flos Lonicerae 20 parts, Radix Glehniae 28 parts, Radix Ranunculi Ternati 15 parts, Radix Rehmanniae 15 parts, Radix Scrophulariae 20 parts, Radix Salviae Miltiorrhizae 25 parts, Medulla Junci 20 parts, Rhizoma Polygonati Odorati 25 parts, Radix Ophiopogonis 20 parts, Rhizoma Belamcandae 15 parts, Flos Chrysanthemi 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of chronic pharyngitis as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of chronic pharyngitis as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment chronic pharyngitis medicine of chronic pharyngitis according to claim 1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510578639.2A CN105106646A (en) | 2015-09-12 | 2015-09-12 | Medicinal preparation for treating chronic pharyngitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510578639.2A CN105106646A (en) | 2015-09-12 | 2015-09-12 | Medicinal preparation for treating chronic pharyngitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999000A (en) * | 2016-06-14 | 2016-10-12 | 罗朝邦 | Traditional Chinese medicine for treating chronic pharyngitis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1600356A (en) * | 2003-09-23 | 2005-03-30 | 山西医科大学第一医院 | Combination of Chinese traditional medicine for curing chronic pharyngitis and preparation method |
| CN101658632A (en) * | 2009-08-27 | 2010-03-03 | 广州白云山和记黄埔中药有限公司 | Chinese herbal preparation for treating chronic pharyngitis and preparation method thereof |
| CN103182023A (en) * | 2013-02-07 | 2013-07-03 | 洛阳市洛铜医院 | Medicine for treating chronic pharyngitis and preparation method thereof |
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- 2015-09-12 CN CN201510578639.2A patent/CN105106646A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1600356A (en) * | 2003-09-23 | 2005-03-30 | 山西医科大学第一医院 | Combination of Chinese traditional medicine for curing chronic pharyngitis and preparation method |
| CN101658632A (en) * | 2009-08-27 | 2010-03-03 | 广州白云山和记黄埔中药有限公司 | Chinese herbal preparation for treating chronic pharyngitis and preparation method thereof |
| CN103182023A (en) * | 2013-02-07 | 2013-07-03 | 洛阳市洛铜医院 | Medicine for treating chronic pharyngitis and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999000A (en) * | 2016-06-14 | 2016-10-12 | 罗朝邦 | Traditional Chinese medicine for treating chronic pharyngitis |
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Application publication date: 20151202 |
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