CN105055845A - Medicine preparation for treating cardiac insufficiency - Google Patents
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- CN105055845A CN105055845A CN201510595366.2A CN201510595366A CN105055845A CN 105055845 A CN105055845 A CN 105055845A CN 201510595366 A CN201510595366 A CN 201510595366A CN 105055845 A CN105055845 A CN 105055845A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations, and particularly provides a medicine preparation for treating cardiac insufficiency. The medicine preparation is prepared from the following raw materials: 28 parts of tailed spicebush root or bark, 18 parts of tropic ageratum herb, 25 parts of biden bipinnata, 18 parts of fmoes officinalis ames, 25 parts of pseudo-ginseng, 15 parts of salvia miltiorrhiza, 20 parts of radix paeoniae alba, 20 parts of pinellia ternata, 25 parts of peach kernels, 25 parts of allium macrostemon, 20 parts of radix ophiopogonis, 15 parts of astragalus membranaceus, 18 parts of ligusticum wallichii, 15 parts of fructus lycii, 20 parts of safflower carthamus, 15 parts of schisandra chinensis and 5 parts of licorice root. The medicine preparation can be used for treating cardiac insufficiency.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of cardiac blood supply deficiency and its preparation method and application.
Background technology
Cardiac blood supply deficiency can cause myocardial ischemia, decreased cardiac function, is the No.1 formidable enemy of harm humans health.The meals that mostly result from are unreasonable, the life factor such as very few that moves causes hyperlipemia, hypercholesterolemia, they can be deposited on arteries inwall, until formation atheromatous plaque, cause angiostenosis even to block, finally can lead to the serious diseases such as coronary heart disease.For this reason, be bursting to and develop the needs that more medicines for the treatment of cardiac blood supply deficiency safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of cardiac blood supply deficiency disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of cardiac blood supply deficiency, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Radix seu Cortex Linderae Caudatae 28 parts, Herba Agerati Conyzoidis 18 parts, Herba bidentis parviflorae 25 parts, Fructificatio Fomitopsis Officinalis 18 parts, Radix Notoginseng 25 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Paeoniae Alba 20 parts, the Rhizoma Pinelliae 20 parts, 25 parts, Semen Persicae, Bulbus Allii Macrostemonis 25 parts, Radix Ophiopogonis 20 parts, the Radix Astragali 15 parts, Rhizoma Chuanxiong 18 parts, Fructus Lycii 15 parts, 20 parts, Flos Carthami, Fructus Schisandrae Chinensis 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of cardiac blood supply deficiency, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of cardiac blood supply deficiency, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment cardiac blood supply deficiency medicine being used for the treatment of cardiac blood supply deficiency.
Radix seu Cortex Linderae Caudatae, Classification system Linderacaudata (Nees) Hook.f. is root, leaf, the skin of canella Lindera caudata.Hemostasia and promoting granulation, regulating QI to relieve pain.Control osteopatia sprain, wound congestive edema, hemorrhage, chest pain is coughed.
Herba Agerati Conyzoidis is Compositae Ageratum plant Ageratum conyzoides AgeratumconyzoidesL., is used as medicine with herb or leaf and tender stem.Xia Qiu gathers, and cleans, using fresh herb or dry.Expelling wind and clearing away heat, pain relieving, hemostasis, calculus.For upper respiratory tract infection, tonsillitis, pharyngolaryngitis, acute gastroenteritis, stomachache, stomachache, metrorrhagia, renal calculus, vesical calculus; Eczema is controlled in external, thrush, carbuncle pyogenic infections from tumour or sore, cellulitis, ulcer of the lower limb, otitis media, traumatic hemorrhage.The present invention is with all herbal medicine.
Herba bidentis parviflorae, Latin is called BidensbipinnataL., Compositae, Herba bidentis parviflorae platymiscium, and Herba bidentis parviflorae is born in hillside, meadow or roadside more.Be widely distributed in all parts of the country.Wanda Mountain district quantity is more.With all herbal medicine.Gather during summer-flowering, cutting, dries.Heat-clearing and toxic substances removing, expelling wind and activating blood circulation.For upper respiratory tract infection, laryngopharynx swelling and pain, acute appendicitis, acute icteric infectious hepatitis, gastroenteritis, dyspepsia, rheumatic arthritis, malaria; Furuncle is controlled in external, venom, treating swelling and pain by traumatic injury.The present invention is with all herbal medicine.
Fructificatio Fomitopsis Officinalis, the cap shape of a hoof, usual fist is greatly or larger, white to faint yellow, the thin skin that initial stage surface tool is smooth, after gradually ftracture roughening, sometimes have concentric endless belt, edge is blunt; Bacterial context is soft, white powder, loose light weight, frangible time old; Tube white, multilamellar.Spore is colourless, smooth, avette, and Classification system is Fomesofficinalis (Vill.EtFr.) Ames, has warming the lung for resolving phlegm, lowering the adverse-rising QI to subdue asthma, expelling wind and removing dampness, promoting blood circulation and detumescence, diuresis, the effect of antidoting against snake bite.For cough, asthma, stomachache, hyperchlorhydria, lithangiuria, nephritis, chronic rheumatic arthritis, pharyngolaryngitis, periodontitis, venom.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that cardiac blood supply deficiency refers to caused by the resistance of QI and blood numbness, stagnation of phlegm blood vessels etc., Radix seu Cortex Linderae Caudatae of the present invention, Herba Agerati Conyzoidis, Herba bidentis parviflorae, Fructificatio Fomitopsis Officinalis, Radix Notoginseng, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, the Rhizoma Pinelliae, Semen Persicae heat-clearing and toxic substances removing, soothing the channels and quicking the network vessels are monarch drug, Bulbus Allii Macrostemonis, Radix Ophiopogonis, the Radix Astragali, Rhizoma Chuanxiong, Fructus Lycii, Flos Carthami, Fructus Schisandrae Chinensis blood circulation promoting and blood stasis dispelling are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, blood circulation promoting and blood stasis dispelling, soothing the channels and quicking the network vessels, treatment cardiac blood supply deficiency successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Radix seu Cortex Linderae Caudatae 28g, Herba Agerati Conyzoidis 18g, Herba bidentis parviflorae 25g, Fructificatio Fomitopsis Officinalis 18g, Radix Notoginseng 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 20g, Rhizoma Pinelliae 20g, Semen Persicae 25g, Bulbus Allii Macrostemonis 25g, Radix Ophiopogonis 20g, Radix Astragali 15g, Rhizoma Chuanxiong 18g, Fructus Lycii 15g, Flos Carthami 20g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Radix seu Cortex Linderae Caudatae 28g, Herba Agerati Conyzoidis 18g, Herba bidentis parviflorae 25g, Fructificatio Fomitopsis Officinalis 18g, Radix Notoginseng 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 20g, Rhizoma Pinelliae 20g, Semen Persicae 25g, Bulbus Allii Macrostemonis 25g, Radix Ophiopogonis 20g, Radix Astragali 15g, Rhizoma Chuanxiong 18g, Fructus Lycii 15g, Flos Carthami 20g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Radix seu Cortex Linderae Caudatae 28g, Herba Agerati Conyzoidis 18g, Herba bidentis parviflorae 25g, Fructificatio Fomitopsis Officinalis 18g, Radix Notoginseng 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 20g, Rhizoma Pinelliae 20g, Semen Persicae 25g, Bulbus Allii Macrostemonis 25g, Radix Ophiopogonis 20g, Radix Astragali 15g, Rhizoma Chuanxiong 18g, Fructus Lycii 15g, Flos Carthami 20g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds starch 50g, granulates, fill, makes capsule.
4, pharmaceutical preparation treatment cardiac blood supply deficiency of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation cardiac blood supply deficiency case 70 example, 48 ~ 65 years old age.The shortest person of the course of disease 6 months, most elder reaches 2 years.
4.2 diagnostic criterias: nervous, cardiopalmus, breathe hard, uncomfortable in chest, chest pain, have an electro-cardiogram and color ultrasound, be diagnosed as cardiac blood supply deficiency.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: symptom all disappears; Effective: symptom obviously alleviates; Invalid: without significant change or deterioration before and after treatment.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 35 | 16 | 17 | 2 | 94.3 |
| Blank group | 35 | 2 | 1 | 32 | 8.6 |
Visible, the medicine that the present invention obtains can safe and effective treatment cardiac blood supply deficiency, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of cardiac blood supply deficiency, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Radix seu Cortex Linderae Caudatae 28 parts, Herba Agerati Conyzoidis 18 parts, Herba bidentis parviflorae 25 parts, Fructificatio Fomitopsis Officinalis 18 parts, Radix Notoginseng 25 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Paeoniae Alba 20 parts, the Rhizoma Pinelliae 20 parts, 25 parts, Semen Persicae, Bulbus Allii Macrostemonis 25 parts, Radix Ophiopogonis 20 parts, the Radix Astragali 15 parts, Rhizoma Chuanxiong 18 parts, Fructus Lycii 15 parts, 20 parts, Flos Carthami, Fructus Schisandrae Chinensis 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of cardiac blood supply deficiency as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of cardiac blood supply deficiency as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment cardiac blood supply deficiency medicine of cardiac blood supply deficiency according to claim 1.
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| CN105412262A (en) * | 2016-01-22 | 2016-03-23 | 宋亚 | Traditional Chinese medicine for treating arteriosclerosis and coronary heart disease as well as preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120115963A (en) * | 2011-04-11 | 2012-10-19 | 성균관대학교산학협력단 | Composition for prevention or treatment of cardiovascular disease containing extracts of dioscorea batatas decne |
| CN104740216A (en) * | 2015-04-15 | 2015-07-01 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating coronary heart disease and stenocardia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120115963A (en) * | 2011-04-11 | 2012-10-19 | 성균관대학교산학협력단 | Composition for prevention or treatment of cardiovascular disease containing extracts of dioscorea batatas decne |
| CN104740216A (en) * | 2015-04-15 | 2015-07-01 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating coronary heart disease and stenocardia |
Non-Patent Citations (4)
| Title |
|---|
| 吕振军: "滨州名医——吕会文", 《山东中医杂志》 * |
| 李明亚: "《临床药物治疗学》", 31 August 2015, 中国医药科技出版社 * |
| 段柏华: "中西结合治疗冠心病心肌缺血50例", 《亚太传统医药》 * |
| 陈晓序: "益气活血汤治疗心绞痛186例", 《陕西中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412262A (en) * | 2016-01-22 | 2016-03-23 | 宋亚 | Traditional Chinese medicine for treating arteriosclerosis and coronary heart disease as well as preparation method and application thereof |
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