CN105031411A - Pharmaceutic preparation for treating internal hemorrhoid - Google Patents
Pharmaceutic preparation for treating internal hemorrhoid Download PDFInfo
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- CN105031411A CN105031411A CN201510580236.1A CN201510580236A CN105031411A CN 105031411 A CN105031411 A CN 105031411A CN 201510580236 A CN201510580236 A CN 201510580236A CN 105031411 A CN105031411 A CN 105031411A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations, and particularly provides a pharmaceutic preparation for treating internal hemorrhoid. The pharmaceutic preparation for treating the internal hemorrhoid is prepared from 25 parts of herbs of paniculate spotflower, 20 parts of thinleaf adina fruit, 18 parts of auriculate swallowwort stems and leaves, 15 parts of roots or stems of evergreen mucuna, 20 parts of Chinese starjasmine stems, 18 parts of flos carthami, 15 parts of peach seeds, 15 parts of semen coicis, 20 parts of fructus arctii, 25 parts of radix angelicae dahuricae, 20 parts of fructus forsythiae, 25 parts of flos chrysanthemi, 20 parts of folium artemisiae argyi, 15 parts of herba equiseti hiemalis, 15 parts of radix paeoniae rubra, 15 parts of herba commelinae, 25 parts of milkvetch roots, 15 parts of radix arnebiae and 5 parts of liquorice. The pharmaceutic preparation can treat the internal hemorrhoid.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of internal hemorrhoid and its preparation method and application.
Background technology
Internal hemorrhoid is more than anus tooth trace there is varicosis agglomerate, and surface is coated with mucosa, and often have blood in stool, blood stasis is deviate from, and constipation etc. are the sick class disease of hemorrhoid of main manifestations.Internal hemorrhoid is that in anorectal disease, modal disease is planted.Internal hemorrhoid is apt to occur in calculi position 3,7,11 point, is also called primary hemorrhoid district, and the internal hemorrhoid that remainder occurs all is called sub-hemorrhoid.Identical with doctor trained in Western medicine name of disease.If primary disease early treatment, general prognosis bona.But also have some patients, occur together in the course of disease complication such as anemia.For this reason, be bursting to and develop the needs that more medicines for the treatment of internal hemorrhoid safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of interior hemorrhoidal diseases.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of internal hemorrhoid, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Spilanthis Acmellae 25 parts, Fructus Adinae 20 parts, Caulis et Folium Cynanchi Auriculati 18 parts, Radix Seu Caulis Mucunae Sempervirentis 15 parts, Caulis Trachelospermi 20 parts, 18 parts, Flos Carthami, 15 parts, Semen Persicae, Semen Coicis 15 parts, Fructus Arctii 20 parts, the Radix Angelicae Dahuricae 25 parts, Fructus Forsythiae 20 parts, Flos Chrysanthemi 25 parts, Folium Artemisiae Argyi 20 parts, Herba Equiseti Hiemalis 15 parts, Radix Paeoniae Rubra 15 parts, Herba Commelinae 15 parts, the Radix Astragali 25 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of internal hemorrhoid, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of internal hemorrhoid, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment internal hemorrhoid medicine being used for the treatment of internal hemorrhoid.
Herba Spilanthis Acmellae, Latin is called HerbofPaniculateSpotflower, for Compositae Spilanthes intends Spilanthes acmella.Detoxification and promoting urination, relieving cough and relieving asthma, reducing swelling and alleviating pain.For malaria, toothache, enteritis, dysentery, cough, asthma, pertussis, pulmonary tuberculosis.Venom is controlled in external, dog bite, carbuncle furuncle and phyma poison.The present invention is with all herbal medicine.
Fructus Adinae is Rubiaceae avens Fructus Adinae AdinarubellaHance, with root, peel of stem, leaf, flower and fruit medicine.Clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main diarrhea due to damp-heat; Dysentery; Eczema; Furuncle toxic swelling; Acute toothache; Traumatic injury; Traumatic hemorrhage.The present invention is with all herbal medicine.
Caulis et Folium Cynanchi Auriculati is Luo Teng section Cynanchum plant Caulis et Folium Cynanchi Auriculati (cynanchum auriculatum Royle) CynanchumauriculatumRoyleexWight, with root or all herbal medicine.Stomach invigorating removing food stagnancy, removing toxic substances and promoting subsidence of swelling.For abdominal pain due to retention of food, stomachache, infantile malnutrition, dysentery; Venom is controlled in external, furuncle.The present invention is with all herbal medicine.
Radix Seu Caulis Mucunae Sempervirentis is the evergreen mucuna MucunasempervirensHemsl. of pulse family Mucuna plant, is used as medicine with root, stem and leaf.The whole year can adopt, and dries respectively.Blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, dredge the meridian passage.For traumatic injury, rheumatalgia, numbness, stimulate the menstrual flow, amenorrhea.The present invention is with all herbal medicine.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that the endogenous cause of ill of internal hemorrhoid is that QI and blood is deficient, exopathogenic factor is that four gas phases conjunctions are taken advantage of a weak point.Because of natural endowment element void, children's's chronic diarrhea chronic dysentery, married woman give birth to too much, old man's QI and blood fails, cause insufficiency of vital energy and blood, the deficiency of vital energy is then sunk, and is difficult to take the photograph receive and cause hemorrhoid and take off and do not receive; Blood deficiency is then raw dry, cause dryness-heat stagnating in the interior consumption impairment of body fluid liquid, be difficult lubricious large intestine, be hard and dry, defecation is exerted and is earned, cause anus qi depression to blood stasis, tie stagnant not faling apart and form hemorrhoid, Herba Spilanthis Acmellae of the present invention, Fructus Adinae, Caulis et Folium Cynanchi Auriculati, Radix Seu Caulis Mucunae Sempervirentis, Caulis Trachelospermi, Flos Carthami, Semen Persicae heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling are monarch drug, Semen Coicis, Fructus Arctii, the Radix Angelicae Dahuricae, Fructus Forsythiae, Flos Chrysanthemi, Folium Artemisiae Argyi, Herba Equiseti Hiemalis, Radix Paeoniae Rubra, Herba Commelinae, the Radix Astragali, Radix Arnebiae (Radix Lithospermi) convergence granulation promoting are ministerial drug, Radix Glycyrrhizae is adjuvant, full side compatibility mutually, treatment internal hemorrhoid successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Herba Spilanthis Acmellae 25g, Fructus Adinae 20g, Caulis et Folium Cynanchi Auriculati 18g, Radix Seu Caulis Mucunae Sempervirentis 15g, Caulis Trachelospermi 20g, Flos Carthami 18g, Semen Persicae 15g, Semen Coicis 15g, Fructus Arctii 20g, Radix Angelicae Dahuricae 25g, Fructus Forsythiae 20g, Flos Chrysanthemi 25g, Folium Artemisiae Argyi 20g, Herba Equiseti Hiemalis 15g, Radix Paeoniae Rubra 15g, Herba Commelinae 15g, Radix Astragali 25g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, and atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Herba Spilanthis Acmellae 25g, Fructus Adinae 20g, Caulis et Folium Cynanchi Auriculati 18g, Radix Seu Caulis Mucunae Sempervirentis 15g, Caulis Trachelospermi 20g, Flos Carthami 18g, Semen Persicae 15g, Semen Coicis 15g, Fructus Arctii 20g, Radix Angelicae Dahuricae 25g, Fructus Forsythiae 20g, Flos Chrysanthemi 25g, Folium Artemisiae Argyi 20g, Herba Equiseti Hiemalis 15g, Radix Paeoniae Rubra 15g, Herba Commelinae 15g, Radix Astragali 25g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds dextrin 50g, granulates, tabletting, makes tablet.
3, the preparation of capsule embodiment: get Herba Spilanthis Acmellae 25g, Fructus Adinae 20g, Caulis et Folium Cynanchi Auriculati 18g, Radix Seu Caulis Mucunae Sempervirentis 15g, Caulis Trachelospermi 20g, Flos Carthami 18g, Semen Persicae 15g, Semen Coicis 15g, Fructus Arctii 20g, Radix Angelicae Dahuricae 25g, Fructus Forsythiae 20g, Flos Chrysanthemi 25g, Folium Artemisiae Argyi 20g, Herba Equiseti Hiemalis 15g, Radix Paeoniae Rubra 15g, Herba Commelinae 15g, Radix Astragali 25g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds starch 50g, granulates, fill, makes capsule.
4, pharmaceutical preparation treatment internal hemorrhoid of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation internal hemorrhoid case 40 example, 35 ~ 67 years old age.The shortest person of the course of disease 2 months, most elder reaches 2 years.
4.2 diagnostic criterias: be mainly in adult, onset is often had blood in stool as cardinal symptom with Silent Neuritis, and blood does not mix mutually with stool, how to bleed when defecation or to penetrate blood.Hemorrhage in intermittent, often because of drinking, overwork, constipation or make when suffering from diarrhoea to have blood in stool to recur and increase the weight of.Hemorrhage serious time can cause anemia.See when anus is looked into that on tooth trace, mucosa is hemispherical protuberance, color is scarlet, dark red or greyish white.Along with blood stasis increases, when defecation or cough time can deviate from outside anus, if Hui Na not in time, can incarceration of internal hemorrhoid be formed, and have secretions to overflow, rectal tenesmus; Different according to severe extent, can be divided into for three phases: 1. I phase: blood stasis is less, as Semen Glycines or Semen Viciae fabae large, color is scarlet, and matter is soft, does not deviate from outside anus, stool band blood or bleed.2. II phase: blood stasis is comparatively large, likeness in form Fructus Jujubae, color is dark red, deviates from outside anus during stool, can also receive voluntarily after an action of the bowels, and stool bleeds more or penetrates blood one line as arrow.3. III phase: blood stasis is larger, as egg or larger, color is greyish white, during stool or walking time deviate from outside anus, can not also receive voluntarily, generally not hemorrhage, once hemorrhage, in spurting, blood stasis deviate from after if also do not received as early as possible, then easily incarceration and strangulation swelling, rotten to the corn necrosis.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: symptom all disappears; Effective: symptom obviously alleviates; Invalid: without significant change or deterioration before and after treatment.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 20 | 6 | 8 | 6 | 70 |
| Blank group | 20 | 0 | 1 | 19 | 5 |
Visible, the medicine that the present invention obtains can safe and effective treatment internal hemorrhoid, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of internal hemorrhoid, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Spilanthis Acmellae 25 parts, Fructus Adinae 20 parts, Caulis et Folium Cynanchi Auriculati 18 parts, Radix Seu Caulis Mucunae Sempervirentis 15 parts, Caulis Trachelospermi 20 parts, 18 parts, Flos Carthami, 15 parts, Semen Persicae, Semen Coicis 15 parts, Fructus Arctii 20 parts, the Radix Angelicae Dahuricae 25 parts, Fructus Forsythiae 20 parts, Flos Chrysanthemi 25 parts, Folium Artemisiae Argyi 20 parts, Herba Equiseti Hiemalis 15 parts, Radix Paeoniae Rubra 15 parts, Herba Commelinae 15 parts, the Radix Astragali 25 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of internal hemorrhoid as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of internal hemorrhoid as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment internal hemorrhoid medicine of internal hemorrhoid according to claim 1.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406587A (en) * | 2008-11-18 | 2009-04-15 | 蒋月芳 | Oral medicament for treating hemorrhoid |
| CN101632773A (en) * | 2008-07-22 | 2010-01-27 | 天津达仁堂京万红药业有限公司 | Chinese medicinal composition for treating haemorrhoids and preparation method thereof |
| CN104258027A (en) * | 2014-09-09 | 2015-01-07 | 张育海 | Traditional Chinese medicine for treating internal hemorrhoids |
| CN104784618A (en) * | 2015-04-23 | 2015-07-22 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating headache |
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- 2015-09-14 CN CN201510580236.1A patent/CN105031411A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101632773A (en) * | 2008-07-22 | 2010-01-27 | 天津达仁堂京万红药业有限公司 | Chinese medicinal composition for treating haemorrhoids and preparation method thereof |
| CN101406587A (en) * | 2008-11-18 | 2009-04-15 | 蒋月芳 | Oral medicament for treating hemorrhoid |
| CN104258027A (en) * | 2014-09-09 | 2015-01-07 | 张育海 | Traditional Chinese medicine for treating internal hemorrhoids |
| CN104784618A (en) * | 2015-04-23 | 2015-07-22 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating headache |
Non-Patent Citations (1)
| Title |
|---|
| 赵红波等: "清热活血法在痔病术后的用药规律", 《世界华人消化杂志》 * |
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Application publication date: 20151111 |