CN105012479A - Acne treatment composition and application thereof and acne treatment cream containing acne treatment composition - Google Patents

Acne treatment composition and application thereof and acne treatment cream containing acne treatment composition Download PDF

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CN105012479A
CN105012479A CN201510433429.4A CN201510433429A CN105012479A CN 105012479 A CN105012479 A CN 105012479A CN 201510433429 A CN201510433429 A CN 201510433429A CN 105012479 A CN105012479 A CN 105012479A
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extract
acne
parts
removing composition
acne treatment
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CN105012479B (en
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李红军
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Kerma (unit Of Kinetic Energy) Bio Tech Ltd Guangzhou
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Kerma (unit Of Kinetic Energy) Bio Tech Ltd Guangzhou
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Abstract

The invention discloses an acne treatment composition and application thereof and an acne treatment cream containing the acne treatment composition. The acne treatment composition comprises shea butter, Chinese corktree bark extract, salix nigra bark extract, herba portulacae extract, purple perilla extract, asiatic pennywort herb extract and mung bean extract, effectively conditions acne skins and inhibits reproduction of acne, smoothens acne and removes acne marks, and can be applied to skin directly or added into acne treatment products. The acne treatment cream comprises the acne treatment composition, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, propylene glycol, polyacrylamide, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methl glucse sesquistearate, menthol, borneol, edta disodium, methylparaben, propyl hydroxybenzoate and water. The acne treatment cream prepared by a hypo-allergenic formula is mild and non-irritating, easy to absorb, non-greasy, safe and effective.

Description

A kind of acne-removing composition and application thereof with contain the Whelk-eliminating paste of this acne-removing composition
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of acne-removing composition and application and the Whelk-eliminating paste containing this acne-removing composition in anti-acne skin care item.
Background technology
Pox is being commonly called as of acne, cries again " pimples " " acne " " whelk " " skin sore " etc., is that a kind of chronic inflammatory skin that inflammation causes is sick because hair follicle and sebaceous gland are blocked.During adolescence, the hormone meeting stimulating hair growth in body, promote smegma more heavy wool fat, therefore hair and sebaceous gland pile up many materials, make oils and fats and bacterial adhesion, cause the reaction of red swelling of the skin.Because this symptom is common in youth of both sexes, so just claim it to be " comedo ".In fact, teenager not necessarily all can long comedo, and comedo also not necessarily only appears at it teenager.Because present environmental pollution is serious, the dust in air etc. directly contact with face skin, are easy to be adsorbed on skin block pore, and computer radiate source has influence on the disorder of human endocrine system, thus makes skin metabolism irregular; Diet is irregular, poor sleep, pressure etc. all can cause growing of pox.
The method of existing anti-acne has a variety of, 1, as laser therapy comedo method, its energy rapid damage propanoic acid comedo bacillus, effective anti-bacteria breeding, eliminate it to the stimulation of tissue and destruction, but the effect of laser therapy is too strong, and just physical method destroys funny, can not fundamentally anti-acne; 2, some natural plant component, Chinese medicinal ingredients or the Chinese medicines such as Aloe, Flos Matricariae chamomillae, Camellia sinensis, Fructus Hippophae are utilized to mix composition anti-acne with plant, existing this anti-acne method safety, regulation of skin oils and fats can be played thus the effect of fundamentally anti-acne, but marking when using this natral plant ingredients anti-acne after time length, anti-acne is not easily removed completely, and formula needs to be improved; 3, utilize some Western medicine such as salicylic acid, Bo Nisong, dexamethasone except pox, the side effect of Western medicine is strong, and cost is high.Therefore, be necessary that a kind of effectively conditioning of research and development pox flesh suppresses small pox regeneration, smooth pox hole, and gentleness do not stimulate, the Whelk-eliminating paste of hypoallergenic safety.
Chinese patent application CN 103622885A discloses a kind of acne-removing composition containing Butyrospermum parkii fruit fat, Angelica roots, Rhizoma Atractylodis Macrocephalae root extract, Herba Centellae extract.Chinese patent application CN 104586667A discloses a kind of acne eliminating cream containing Cortex Phellodendri extract, Radix Sophorae Flavescentis extract, Herba Lophatheri extract etc.Chinese patent application CN 104188849A discloses a kind of anti-acne control fluid composition containing Herba portulacae extract, white willow peel extract.Through retrieval, not yet find that there is compositions and the application of said composition in anti-acne skin care item of Butyrospermum parkii fruit fat, Cortex Phellodendri extract, black extract of willow bark, Herba portulacae extract, Folium perillae extract, Herba Centellae extract and Semen phaseoli radiati extract at present.
Summary of the invention
The object of the present invention is to provide a kind of acne-removing composition, this acne-removing composition can effectively be nursed one's health pox flesh and suppress small pox to regenerate, and smooths pox hole, desalination pox print.
The present invention is by the following technical programs to realize above-mentioned purpose: a kind of acne-removing composition, comprises following component: Butyrospermum parkii fruit fat, Cortex Phellodendri extract, black extract of willow bark, Herba portulacae extract, Folium perillae extract, Herba Centellae extract and Semen phaseoli radiati extract.
Further, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 10 ~ 30 parts, fat, Cortex Phellodendri extract 2 ~ 8 parts, black extract of willow bark 2 ~ 8 parts, Herba portulacae extract 2 ~ 10 parts, Folium perillae extract 2 ~ 8 parts, Herba Centellae extract 2 ~ 8 parts and Semen phaseoli radiati extract 3 ~ 10 parts.
As the preferred embodiment of the present invention, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 20 parts, fat, Cortex Phellodendri extract 5 parts, black extract of willow bark 6 parts, Herba portulacae extract 8 parts, Folium perillae extract 5 parts, Herba Centellae extract 5 parts and Semen phaseoli radiati extract 8 parts.
The function and structure of described Butyrospermum parkii fruit fat is very similar to the lipid of skin, therefore be considered to a kind of natural Moisture factor, it can help epidermis cell structure to keep complete, effectively to antibacterium, be conducive to skin healing, prevent skin irritation and make skin regeneration.
Described Cortex Phellodendri extract has the effect of releiving with calm skin, can help rapidly releive skin redness and inflammation situation, and horny layer softening, deep layer reparation, composes flesh floor cells of living.
Described black extract of willow bark is set from the black wool of North American continent east, and fresh black wool tree is containing abundant tannic acid and salicylic acid, and natural salicylic acid to infiltrate through in pore as beta-hydroxy acid thus enter skin depths, does not stimulate while antibacterial.
Described Herba portulacae extract has the effects such as antioxidation, antiinflammatory, moisturizing, and the sense of discomfort of skin of softly releiving, takees good care of tender and lovely skin quality.
Described Folium perillae extract can infiltrate skin very well, alleviates small pox inflammation, reduces the generation of pox print.
Described Herba Centellae extract can promote that in skin corium, collagen protein is formed, and makes fibrin regenerate, makes skin compact smooth, also can help impaired organization healing.
Aminoacid, alkaloid etc. that described Semen phaseoli radiati extract is contained abundant, have the effect of skin of releiving, repair, can remove the dirt of skin pore depths, improves and prevention skin is fuel-displaced, dark and gloomy and small pox problem.
Described Butyrospermum parkii fruit fat and black extract of willow bark effectively antibacterial, but not chafe; Described Cortex Phellodendri extract and Herba portulacae extract are effectively releived the sense of discomfort such as red swelling of the skin, inflammation; Described Folium perillae extract, snow grass extract and Semen phaseoli radiati extract effectively dissolve pore depths grease soils, dredge blockage hair follicle, discharge toxin, reduce pox print, improve skin quality; The each component of acne-removing composition of the present invention is worked in coordination with, and reaches effectively conditioning pox flesh, suppresses small pox regeneration, improve pockmark pox print and skin coarse, progressively deeply desalinate pox print, promote that skin horny layer upgrades, the object of reparation skin.Therefore, directly can be coated with or add in anti-acne skin care item after acne-removing composition mix homogeneously of the present invention and use.
Another object of the present invention is to provide a kind of Whelk-eliminating paste containing acne-removing composition of the present invention and preparation method thereof, and its technical scheme is as follows:
A kind of Whelk-eliminating paste, comprise the raw material of following weight percent meter: described acne-removing composition 2 ~ 8%, cetearyl alcohol 3 ~ 5%, ethylhexyl palmitate 2 ~ 4%, polydimethylsiloxane 2 ~ 4%, glyceryl stearate 0.5 ~ 2%, PEG-100 stearate 0.5 ~ 2%, caprylic/capric triglyceride 1 ~ 3%, propylene glycol 1 ~ 3%, polyacrylamide 0.5 ~ 1.5%, polysorbate-60 1 ~ 1.5%, sorbitan stearate 0.5 ~ 1.5%, laurocapram 0.2 ~ 0.8%, PEG-20 methyl sesquistearate 0.2 ~ 0.8%, menthol 0.2 ~ 0.8%, Borneolum Syntheticum 0.1 ~ 0.3%, EDTA disodium 0.05 ~ 0.15%, methyl hydroxybenzoate 0.05 ~ 0.3%, propyl hydroxybenzoate 0.05 ~ 0.15% and water 70 ~ 80%.
As the preferred embodiment of the present invention, described Whelk-eliminating paste is made up of the raw material of following weight percent meter: described acne-removing composition 6%, cetearyl alcohol 4%, ethylhexyl palmitate 3%, polydimethylsiloxane 3%, glyceryl stearate 1%, PEG-100 stearate 1%, caprylic/capric triglyceride 2%, propylene glycol 2%, polyacrylamide 1%, polysorbate-60 1.2%, sorbitan stearate 1%, laurocapram 0.6%, PEG-20 methyl sesquistearate 0.5%, menthol 0.5%, Borneolum Syntheticum 0.2%, EDTA disodium 0.1%, methyl hydroxybenzoate 0.2%, propyl hydroxybenzoate 0.1% and water 72.6%.
The preparation method of above-mentioned Whelk-eliminating paste comprises the following steps:
S1, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methyl sesquistearate, methyl hydroxybenzoate and propyl hydroxybenzoate are added in oil phase pot, be heated to 75 ~ 85 DEG C while stirring, and be stirred to material and dissolve completely, obtain material one, for subsequent use;
S2, EDTA disodium, water are added in aqueous phase pot, be stirred and heated to 80 ~ 85 DEG C, in suction reaction pot, then by material one suction, open homogenizing, after adding polyacrylamide homogenizing 5 ~ 10min, after insulated and stirred 15min, start cooling simultaneously, add propylene glycol, menthol, Borneolum Syntheticum, acne-removing composition stirring when 45 DEG C, obtain Whelk-eliminating paste.
Further, the mixing speed of described stirring is 40 ~ 50 revs/min.
Therefore, compared with prior art, advantage of the present invention is:
(1) acne-removing composition of the present invention is made up of various plants extract, does not naturally stimulate, effectively antibacterial, to releive the sense of discomfort such as red swelling of the skin, inflammation, more solubilized pore depths grease soils, dredge blockage hair follicle, discharge toxin, supplement skin desired nutritional elite in time, promote skin reparation, compact skin, smooth pox hole, reduce pox print, improve skin quality, suppress small pox regeneration simultaneously.
(2) Whelk-eliminating paste formula gentleness of the present invention does not stimulate, easily absorptions, non-greasy, safe and efficient, can work in coordination with acne-removing composition of the present invention and infiltrate skin fast, the object reaching safe and efficient anti-acne, repair skin, suppress small pox to regenerate; Whelk-eliminating paste raw material of the present invention is easy to get simultaneously, and preparation technology is simple, and condition is easily controlled, and can be applicable.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
Butyrospermum parkii fruit fat of the present invention is Butyrospermum parkii (BUTYROSPERMUM PARKII) the fruit fat purchased from Li Meida Fine Chemical Co., Ltd, and article No. is ZJF-01200419;
Described Cortex Phellodendri extract is Cortex Phellodendri (PHELLODENDRON AMURENSE) extract purchased from Guangzhou Ming Hui Fine Chemical Co., Ltd, and article No. is R-646;
Described black extract of willow bark is black willow (SALIX NIGRA) bark extract purchased from Guangzhou Ming Hui Fine Chemical Co., Ltd, and article No. is R-633;
Described Herba portulacae extract is Herba Portulacae (PORTULACA OLERACEA) extract purchased from Eurocostech Co., Ltd, and article No. is 2121115;
Described Folium perillae extract is Folium Perillae (PERILLA OCYMOIDES) extract purchased from Xilong Chemical Co., Ltd, and article No. is 150333;
Described Herba Centellae extract is Herba Centellae (CENTELLA ASIATICA) extract purchased from Shanghai Shun Tuo scientific & trading Co., Ltd., and article No. is ZA015;
Described Semen phaseoli radiati extract is Semen phaseoli radiati (PHASEOLUS RADIATUS) extract purchased from Li Meida Fine Chemical Co., Ltd, and article No. is ZJF-01100400.
embodiment 1, acne-removing composition of the present invention
Butyrospermum parkii fruit 20 parts, fat, Cortex Phellodendri extract 5 parts, black extract of willow bark 6 parts, Herba portulacae extract 8 parts, Folium perillae extract 5 parts, Herba Centellae extract 5 parts and Semen phaseoli radiati extract 8 parts.
embodiment 2, acne-removing composition of the present invention
Butyrospermum parkii fruit 10 parts, fat, Cortex Phellodendri extract 8 parts, black extract of willow bark 8 parts, Herba portulacae extract 10 parts, Folium perillae extract 2 parts, Herba Centellae extract 2 parts and Semen phaseoli radiati extract 3 parts.
embodiment 3, acne-removing composition of the present invention
Butyrospermum parkii fruit 30 parts, fat, Cortex Phellodendri extract 2 parts, black extract of willow bark 2 parts, Herba portulacae extract 2 parts, Folium perillae extract 8 parts, Herba Centellae extract 8 parts and Semen phaseoli radiati extract 10 parts.
comparative example 1,
Butyrospermum parkii fruit 26 parts, fat, Herba portulacae extract 13 parts, Folium perillae extract 9 parts and Herba Centellae extract 9 parts.
embodiment 4, Whelk-eliminating paste of the present invention and preparation thereof
Formula: by weight percentage, the acne-removing composition 6% of embodiment 1, cetearyl alcohol 4%, ethylhexyl palmitate 3%, polydimethylsiloxane 3%, glyceryl stearate 1%, PEG-100 stearate 1%, caprylic/capric triglyceride 2%, propylene glycol 2%, polyacrylamide 1%, polysorbate-60 1.2%, sorbitan stearate 1%, laurocapram 0.6%, PEG-20 methyl sesquistearate 0.5%, menthol 0.5%, Borneolum Syntheticum 0.2%, EDTA disodium 0.1%, methyl hydroxybenzoate 0.2%, propyl hydroxybenzoate 0.1% and water 72.6%.
Preparation: S1, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methyl sesquistearate, methyl hydroxybenzoate and propyl hydroxybenzoate are added in oil phase pot, be heated to 80 DEG C while stirring, and be stirred to material and dissolve completely, obtain material one, for subsequent use;
S2, EDTA disodium, water are added in aqueous phase pot, be stirred and heated to 85 DEG C, in suction reaction pot, then by material one suction, open homogenizing, after adding polyacrylamide homogenizing 5min, after insulated and stirred 15min, start cooling simultaneously, add propylene glycol, menthol, Borneolum Syntheticum, acne-removing composition stirring when 45 DEG C, obtain Whelk-eliminating paste.
The mixing speed of above-mentioned stirring is 45 revs/min.
embodiment 5, Whelk-eliminating paste of the present invention and preparation thereof
Formula: by weight percentage, the acne-removing composition 4% of embodiment 1, cetearyl alcohol 5%, ethylhexyl palmitate 2%, polydimethylsiloxane 4%, glyceryl stearate 0.5%, PEG-100 stearate 2%, caprylic/capric triglyceride 1%, propylene glycol 3%, polyacrylamide 0.5%, polysorbate-60 1.5%, sorbitan stearate 0.5%, laurocapram 0.8%, PEG-20 methyl sesquistearate 0.2%, menthol 0.8%, Borneolum Syntheticum 0.1%, EDTA disodium 0.15%, methyl hydroxybenzoate 0.05%, propyl hydroxybenzoate 0.15% and water 73.75%.
Preparation method is with embodiment 4.
embodiment 6, Whelk-eliminating paste of the present invention and preparation thereof
Formula: by weight percentage, the acne-removing composition 8% of embodiment 1, cetearyl alcohol 3%, ethylhexyl palmitate 4%, polydimethylsiloxane 2%, glyceryl stearate 2%, PEG-100 stearate 0.5%, caprylic/capric triglyceride 3%, propylene glycol 1%, polyacrylamide 1.5%, polysorbate-60 1%, sorbitan stearate 1.5%, laurocapram 0.2%, PEG-20 methyl sesquistearate 0.8%, menthol 0.2%, Borneolum Syntheticum 0.3%, EDTA disodium 0.05%, methyl hydroxybenzoate 0.3%, propyl hydroxybenzoate 0.05% and water 70.6%.
Preparation method is with embodiment 4.
test example one, Product Safety evaluation (experiment of human body skin patch)
One, trial target: the acne-removing composition of embodiment 1 ~ 3, the Whelk-eliminating paste of embodiment 4 ~ 6
Tested crowd's number: 60 people, women
Age: between 20 ~ 50 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: 6 groups, often organize 10 people, 28 ± 2 years old mean age.
Two, patch method: select qualified speckle examination device, with closed patch experiment method, tested material being about 0.020g ~ 0.025g drips in speckle examination device, external special adhesive tape is covered on experimenter back, tested material is removed after 24 hours, within after removing respectively 0.5,6,12,24,48 hour, observe dermoreaction, according to its result of dermoreaction grade scale record in " cosmetics health specification ".
Three, experimental result: human skin patch result shows: each group experimenter is by the patch test of the acne-removing composition of embodiment 1 ~ 3, the Whelk-eliminating paste of embodiment 4 ~ 6, dermoreaction is observed at 0.5,6,12,24,48 hour, wherein there is skin adverse reaction in 0 example, the acne-removing composition described in explanation and Whelk-eliminating paste use safety.
the stability test of test example two, Whelk-eliminating paste
Do testing performance index to the Whelk-eliminating paste of embodiment 4, its test result is as follows:
1, heat-resistant stability investigates (40 DEG C × 30 days): qualified;
2, cold-resistant study on the stability (-10 DEG C × 30 days): qualified.
This test example two illustrates the Whelk-eliminating paste good stability of embodiment 4.
test example three, product effect assessment
One, given the test agent: the acne-removing composition of embodiment 1 ~ 3, comparative example 1; The Whelk-eliminating paste that embodiment 4 ~ 6 is obtained
Two, tested crowd
Sex number: female, 84 people; Man 56 people
Age: between 20 ~ 40 years old
Skin: face has obvious acne and small pox, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: be divided into 7 groups, often organize 20 people, female 12 people, male 8 people.
Method of testing: get appropriate given the test agent and be coated in clean affected part, every day 2 times, each 1 time sooner or later, 2 weeks on probation; Experimenter keeps good daily life system time and dietary habit in the trial employment period.The feedback of statistics experimenter after 2 weeks, concrete outcome sees the following form 1 ~ 7.
The test result of table 1 embodiment 1 acne-removing composition
The test result of table 2 embodiment 2 acne-removing composition
The test result of table 3 embodiment 3 acne-removing composition
The test result of table 4 comparative example 1 acne-removing composition
The test result of table 5 embodiment 4 acne-removing composition
The test result of table 6 embodiment 5 acne-removing composition
The test result of table 7 embodiment 6 acne-removing composition
(1) from table 1 ~ 4, the embodiment of the present invention 1 ~ 3 acne-removing composition obtains the accreditation of nearly all experimenter, it is effective that its anti-acne, acne removing print, pox flesh can be repaired simultaneously, namely the situations such as red swelling of the skin, coarse, fat secretion is vigorous are improved, reduce small pox regeneration, wherein the highest with the degree of recognition of the acne-removing composition of embodiment 1; Comparative example 1 has lacked some component compared with embodiment 1 ~ 3, and its effect, all not as good as embodiment 1 ~ 3, illustrates to there is synergism between each component of acne-removing composition of the present invention.
(2) from table 5 ~ 7, the embodiment of the present invention 4 ~ 6 Whelk-eliminating paste obtains the accreditation of nearly all experimenter equally, and its anti-acne, acne removing print, repair the effective of pox flesh, and wherein with embodiment 4 Whelk-eliminating paste best results, degree of recognition is the highest; Compared with acne-removing composition, the degree of recognition of Whelk-eliminating paste is higher, prove Whelk-eliminating paste anti-acne of the present invention, acne removing print, repair the effect of pox flesh more obviously, illustrate that Whelk-eliminating paste formula of the present invention can work in coordination with the effect that acne-removing composition of the present invention reaches anti-acne, acne removing print, reparation pox flesh better.
There is not people to occur allergic phenomena in whole experimenter simultaneously, all do not occur the situations such as skin pruritus, twinge, redness yet.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.

Claims (8)

1. an acne-removing composition, is characterized in that, comprises following component: Butyrospermum parkii fruit fat, Cortex Phellodendri extract, black extract of willow bark, Herba portulacae extract, Folium perillae extract, Herba Centellae extract and Semen phaseoli radiati extract.
2. acne-removing composition as claimed in claim 1, it is characterized in that, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 10 ~ 30 parts, fat, Cortex Phellodendri extract 2 ~ 8 parts, black extract of willow bark 2 ~ 8 parts, Herba portulacae extract 2 ~ 10 parts, Folium perillae extract 2 ~ 8 parts, Herba Centellae extract 2 ~ 8 parts and Semen phaseoli radiati extract 3 ~ 10 parts.
3. acne-removing composition as claimed in claim 2, it is characterized in that, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 20 parts, fat, Cortex Phellodendri extract 5 parts, black extract of willow bark 6 parts, Herba portulacae extract 8 parts, Folium perillae extract 5 parts, Herba Centellae extract 5 parts and Semen phaseoli radiati extract 8 parts.
4. the application of the acne-removing composition as described in as arbitrary in claim 1 ~ 3 in preparation anti-acne skin care item.
5. a Whelk-eliminating paste, it is characterized in that, comprise the raw material of following weight percent meter: the arbitrary described acne-removing composition 2 ~ 8% of claim 1 ~ 3, cetearyl alcohol 3 ~ 5%, ethylhexyl palmitate 2 ~ 4%, polydimethylsiloxane 2 ~ 4%, glyceryl stearate 0.5 ~ 2%, PEG-100 stearate 0.5 ~ 2%, caprylic/capric triglyceride 1 ~ 3%, propylene glycol 1 ~ 3%, polyacrylamide 0.5 ~ 1.5%, polysorbate-60 1 ~ 1.5%, sorbitan stearate 0.5 ~ 1.5%, laurocapram 0.2 ~ 0.8%, PEG-20 methyl sesquistearate 0.2 ~ 0.8%, menthol 0.2 ~ 0.8%, Borneolum Syntheticum 0.1 ~ 0.3%, EDTA disodium 0.05 ~ 0.15%, methyl hydroxybenzoate 0.05 ~ 0.3%, propyl hydroxybenzoate 0.05 ~ 0.15% and water 70 ~ 80%.
6. Whelk-eliminating paste as claimed in claim 5, it is characterized in that, be made up of the raw material of following weight percent meter: the arbitrary described acne-removing composition 6% of claim 1 ~ 3, cetearyl alcohol 4%, ethylhexyl palmitate 3%, polydimethylsiloxane 3%, glyceryl stearate 1%, PEG-100 stearate 1%, caprylic/capric triglyceride 2%, propylene glycol 2%, polyacrylamide 1%, polysorbate-60 1.2%, sorbitan stearate 1%, laurocapram 0.6%, PEG-20 methyl sesquistearate 0.5%, menthol 0.5%, Borneolum Syntheticum 0.2%, EDTA disodium 0.1%, methyl hydroxybenzoate 0.2%, propyl hydroxybenzoate 0.1% and water 72.6%.
7. the preparation method of the Whelk-eliminating paste as described in as arbitrary in claim 5 ~ 6, is characterized in that, comprise the following steps:
S1, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methyl sesquistearate, methyl hydroxybenzoate and propyl hydroxybenzoate are added in oil phase pot, be heated to 75 ~ 85 DEG C while stirring, and be stirred to material and dissolve completely, obtain material one, for subsequent use;
S2, EDTA disodium, water are added in aqueous phase pot, be stirred and heated to 80 ~ 85 DEG C, in suction reaction pot, then by material one suction, open homogenizing, after adding polyacrylamide homogenizing 5 ~ 10min, after insulated and stirred 15min, start cooling simultaneously, add propylene glycol, menthol, Borneolum Syntheticum, acne-removing composition stirring when 45 DEG C, obtain Whelk-eliminating paste.
8. the preparation method of Whelk-eliminating paste as claimed in claim 7, it is characterized in that, the mixing speed of described stirring is 40 ~ 50 revs/min.
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CN105616522A (en) * 2016-03-02 2016-06-01 广州千百度化妆品有限公司 Traditional Chinese medicine acne cream
CN107753379A (en) * 2017-12-05 2018-03-06 佛山微赢电子商务有限公司 It is a kind of effectively anti-acne to desalinate Whelk-eliminating paste of pockmark and preparation method thereof simultaneously
CN108294992A (en) * 2018-03-31 2018-07-20 佛山文森特知识产权服务有限公司 A kind of acne-removing composition
CN108434032A (en) * 2018-04-27 2018-08-24 安婕妤化妆品科技股份有限公司 A kind of anti-acne skin care item and preparation method thereof
CN108938511A (en) * 2018-10-16 2018-12-07 湖南诺泽生物科技有限公司 The composition of natural plant extracts and the application in skin moisture-keeping product for resolving poxes
CN105326730B (en) * 2015-12-16 2018-12-25 广州市中通生化制品有限公司 A kind of acne-removing composition and preparation method thereof containing Chinese herbal medicine extract
WO2019136105A1 (en) * 2018-01-02 2019-07-11 Skinkick, Llc Topical skin care compositions
CN110051761A (en) * 2019-06-12 2019-07-26 郑州植美堂生物科技有限公司 Topical agent of acne-removing inflammation-diminishing and preparation method thereof
CN110051548A (en) * 2019-04-19 2019-07-26 广州市巨匠美容发展有限公司 A kind of ferment enzyme Deacne pack and preparation method thereof
CN111135280A (en) * 2020-01-15 2020-05-12 威海盛朗生物科技有限公司 A pharmaceutical composition, ointment and plaster for treating arthritis
CN111743831A (en) * 2020-06-24 2020-10-09 广州品赫生物科技有限公司 Acne removing composition
CN112006956A (en) * 2020-09-04 2020-12-01 广州莱梧生物科技有限公司 Acne-removing cream and preparation process thereof
CN112107520A (en) * 2020-10-22 2020-12-22 广州科盈化妆品有限公司 Acne-removing composition and preparation method and application thereof
CN112451453A (en) * 2020-11-30 2021-03-09 重庆中佳信生物科技有限公司 Bamboo extract acne-removing cream and preparation method thereof
CN113116777A (en) * 2021-04-14 2021-07-16 浙江目中明生物科技有限公司 Acne removing composition and preparation method of acne removing cream thereof
CN113995701A (en) * 2021-11-06 2022-02-01 马丙生 Composition for removing acne and acne marks and preparation method and application thereof
CN115120537A (en) * 2022-04-02 2022-09-30 广东机电职业技术学院 Acne-removing, oil-controlling and anti-inflammatory multi-effect repair face cream and preparation method thereof
CN115337252A (en) * 2022-08-22 2022-11-15 广州药妆日用化工有限公司 Acne-removing cream with acne-removing, inflammation-diminishing and skin-repairing effects and preparation method thereof
CN117243834A (en) * 2023-10-09 2023-12-19 广州百孚润化工有限公司 Oil-control acne-removing composition with high octanoyl glycine content, and preparation method and application thereof

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CN105326730B (en) * 2015-12-16 2018-12-25 广州市中通生化制品有限公司 A kind of acne-removing composition and preparation method thereof containing Chinese herbal medicine extract
CN105616522A (en) * 2016-03-02 2016-06-01 广州千百度化妆品有限公司 Traditional Chinese medicine acne cream
CN107753379A (en) * 2017-12-05 2018-03-06 佛山微赢电子商务有限公司 It is a kind of effectively anti-acne to desalinate Whelk-eliminating paste of pockmark and preparation method thereof simultaneously
US20200384055A1 (en) * 2018-01-02 2020-12-10 Skinkick, Llc Topical Skin Care Compositions
WO2019136105A1 (en) * 2018-01-02 2019-07-11 Skinkick, Llc Topical skin care compositions
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CN108434032A (en) * 2018-04-27 2018-08-24 安婕妤化妆品科技股份有限公司 A kind of anti-acne skin care item and preparation method thereof
CN108938511B (en) * 2018-10-16 2021-07-16 湖南诺泽生物科技有限公司 Composition of natural plant extracts and application of composition in skin moisturizing and acne removing products
CN108938511A (en) * 2018-10-16 2018-12-07 湖南诺泽生物科技有限公司 The composition of natural plant extracts and the application in skin moisture-keeping product for resolving poxes
CN110051548A (en) * 2019-04-19 2019-07-26 广州市巨匠美容发展有限公司 A kind of ferment enzyme Deacne pack and preparation method thereof
CN110051761A (en) * 2019-06-12 2019-07-26 郑州植美堂生物科技有限公司 Topical agent of acne-removing inflammation-diminishing and preparation method thereof
CN111135280A (en) * 2020-01-15 2020-05-12 威海盛朗生物科技有限公司 A pharmaceutical composition, ointment and plaster for treating arthritis
CN111743831A (en) * 2020-06-24 2020-10-09 广州品赫生物科技有限公司 Acne removing composition
CN112006956A (en) * 2020-09-04 2020-12-01 广州莱梧生物科技有限公司 Acne-removing cream and preparation process thereof
CN112107520A (en) * 2020-10-22 2020-12-22 广州科盈化妆品有限公司 Acne-removing composition and preparation method and application thereof
CN112451453A (en) * 2020-11-30 2021-03-09 重庆中佳信生物科技有限公司 Bamboo extract acne-removing cream and preparation method thereof
CN113116777A (en) * 2021-04-14 2021-07-16 浙江目中明生物科技有限公司 Acne removing composition and preparation method of acne removing cream thereof
CN113995701A (en) * 2021-11-06 2022-02-01 马丙生 Composition for removing acne and acne marks and preparation method and application thereof
CN113995701B (en) * 2021-11-06 2023-07-07 南京苗坊净颜生物科技有限公司 Composition for removing acnes and acne marks as well as preparation method and application thereof
CN115120537A (en) * 2022-04-02 2022-09-30 广东机电职业技术学院 Acne-removing, oil-controlling and anti-inflammatory multi-effect repair face cream and preparation method thereof
CN115337252A (en) * 2022-08-22 2022-11-15 广州药妆日用化工有限公司 Acne-removing cream with acne-removing, inflammation-diminishing and skin-repairing effects and preparation method thereof
CN117243834A (en) * 2023-10-09 2023-12-19 广州百孚润化工有限公司 Oil-control acne-removing composition with high octanoyl glycine content, and preparation method and application thereof
CN117243834B (en) * 2023-10-09 2024-04-26 广州百孚润化工有限公司 Oil-control acne-removing composition with high octanoyl glycine content, and preparation method and application thereof

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