CN109260075B - Acne-removing conditioning water - Google Patents
Acne-removing conditioning water Download PDFInfo
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- CN109260075B CN109260075B CN201811207347.8A CN201811207347A CN109260075B CN 109260075 B CN109260075 B CN 109260075B CN 201811207347 A CN201811207347 A CN 201811207347A CN 109260075 B CN109260075 B CN 109260075B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention discloses acne-removing conditioning water which comprises an acne-removing composition A; the weight percentage content of the acne-removing composition A in the acne-removing conditioning water is 0.4-0.6%; the acne-removing composition A comprises salvia miltiorrhiza root extract, clove bud extract, scutellaria baicalensis root extract, angelica root extract, liquorice root extract and centella asiatica extract. According to the acne-removing conditioning water, mild plant extract components are added and matched with basic raw materials to prepare the acne-removing conditioning water, so that skin pores can be opened, the water-oil balance of the skin can be maintained, the hair follicle keratinization of the skin can be improved, acne can be removed, acne marks can be reduced, damaged skin can be repaired, and the natural health state of the skin can be recovered.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to acne removing conditioning water.
Background
With the development of economy and the continuous improvement of life quality, the acne removing consciousness of Chinese acne patients is improved year by year. The combined survey results of the Chinese dermatosis society and the Chinese teenager union show that the incidence of acne in China is on a rising trend year by year, more than 80% of young people suffer from the problem of acne in different degrees, and the serious disease condition of the young people is more than 1/3.
Acne is commonly known as acne, also called as "whelk", "pimple" or "comedo", and is a skin disease caused by the blockage and inflammation of hair follicles and sebaceous glands. At puberty, the hormone in the body stimulates hair growth and promotes sebaceous gland to secrete more oil, and the hair and sebaceous gland accumulate a lot of substances, which is called as acne because the symptom is common to young men and women.
Acne is a common chronic skin disease, the number of teenagers is the highest, the acne is frequently found on the face, chest and back, and various skin injuries such as blackheads, papules, pustules, nodules, cysts, scars and the like are shown, so that the acne hinders the appearance. The main cause of the whelk is acne caused by the accumulation of sebum due to the blockage of pores caused by the accumulation of sebum, which once infected will deteriorate in a short time to form severe cysts or abscesses.
Acne itself is not afraid, and the biggest harm is that acne marks, acne pits and acne scars are easy to remain in time or irregular treatment, and the image is seriously influenced. Pockmarks are actually inflammatory attacks that, in addition to manual squeezing, damage the epidermis, dermis and underlying subcutaneous tissues of the skin, resulting in skin destruction, tissue defects and scar formation. These problems not only seriously affect the appearance, but also have certain difficulties in treatment.
Therefore, for the acne-removing population, in order to completely remove acne marks, a safe and effective acne-removing product is essential except for paying attention to daily diet and living habits.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide the acne-removing conditioning water.
In order to achieve the purpose, the invention adopts the technical scheme that: an acne-removing conditioning water comprises an acne-removing composition A; the weight percentage content of the acne-removing composition A in the acne-removing conditioning water is 0.4-0.6%; the acne-removing composition A comprises salvia miltiorrhiza root extract, clove bud extract, scutellaria baicalensis root extract, angelica root extract, liquorice root extract and centella asiatica extract.
According to the acne-removing composition A, the salvia miltiorrhiza root extract has the effects of inhibiting bacteria, controlling oil and diminishing inflammation, the angelica root extract has the effects of promoting blood circulation to remove blood stasis and improving follicular keratosis, the licorice root extract and the centella asiatica extract have the effects of harmonizing and repairing, and the clove bud extract and the scutellaria baicalensis root extract can promote the transdermal absorption of the salvia miltiorrhiza root extract, the angelica root extract, the licorice root extract, the centella asiatica extract and the like and dredge pores, so that safe and effective acne removal is realized. The acne-removing composition A has the following characteristics: 1) inhibiting 5 alpha-reductase activity, balancing sebum secretion; 2) inhibiting the growth of acne-related pathogenic flora in the follicular sebum, inhibiting bacteria and diminishing inflammation; 3) good acne inhibiting activity, and can improve skin acne caused by cosmetics; 4) the acne removing effect is synergistically improved through three ways of promoting penetration and absorption, dredging pores and improving follicular keratosis.
The acne-removing composition A can achieve the acne-removing effect in the conditioning water by adopting the addition amount, and the aim of efficient utilization is fulfilled.
Preferably, the acne-removing composition A comprises the following components in parts by weight: 10-20 parts of salvia miltiorrhiza root extract, 2-4 parts of clove bud extract, 1-3 parts of scutellaria baicalensis root extract, 1-3 parts of angelica sinensis root extract, 0.5-2 parts of licorice root extract and 0.5-2 parts of centella asiatica extract.
More preferably, the acne-removing composition a comprises the following components in parts by weight: 15 parts of salvia miltiorrhiza root extract, 3 parts of clove bud extract, 2 parts of scutellaria baicalensis root extract, 2 parts of angelica root extract, 1 part of liquorice root extract and 1 part of centella extract. When the extracts are mixed according to the proportion, the extracts can fully exert respective functions.
Preferably, the conditioning water further comprises an acne-removing composition B; the weight percentage of the acne-removing composition B in the acne-removing conditioning water is 0.4-0.6%; the acne-removing composition B comprises oldenlandia diffusa extract, honeysuckle extract and Chinese honey locust seed extract.
The oldenlandia diffusa extract has anti-inflammatory and antibacterial effects, and has different degrees of antibacterial and bactericidal effects on cocci and bacilli; the honeysuckle stem has the functions of antibiosis and antiphlogosis, and has obvious bacteriostatic activity on staphylococcus aureus and propionibacterium acnes. The acne-removing composition B has a remarkable inhibiting effect on 5 alpha-reductase by matching of the extracts, can relieve acne symptoms, can reduce acne marks, and has an oil control effect. The acne-removing composition B and the acne-removing composition A are matched together, so that acne can be effectively relieved, cells can be helped to regenerate, damaged cell tissues can be repaired, fibrous tissue reconstruction is activated, the skin is smooth and fine, roughness is smoothed, moisture and nutrition are supplemented, the skin is soft, moist and elastic, and acne-removing is realized. And the acne removing composition B can achieve the effect of removing acne marks in conditioning water by adopting the addition amount, and the efficient utilization of the composition B is realized.
Preferably, the acne-removing composition B comprises the following components in parts by weight: 2-4 parts of oldenlandia diffusa extract, 2-4 parts of honeysuckle extract and 0.5-2 parts of Chinese honey locust seed extract. When the extracts are mixed according to the proportion, the extracts can fully exert respective functions.
More preferably, the acne-removing composition B comprises the following components in parts by weight: 3 parts of oldenlandia diffusa extract, 3 parts of honeysuckle extract and 1 part of Chinese honey locust seed extract.
Preferably, the conditioning water also comprises 0.14-0.26% of guava fruit extract. The guava fruit extract has the effects of diminishing inflammation and resisting bacteria, and the added amount is matched with the acne-removing composition A and the acne-removing composition B to play the effects.
Preferably, the conditioning water further comprises a skin-activating ingredient; the skin-active ingredient comprises niacinamide; the weight percentage content of the nicotinamide in the conditioning water is 1-2%.
The nicotinamide can activate skin, infiltrate stratum corneum, promote skin absorption of plant extracts such as acne removing composition A, acne removing composition B and cortex Phellodendri extract of fructus Psidii Guajavae Immaturus extract, improve hair follicle keratinization, and control oil.
Preferably, the conditioning water further comprises a humectant; the moisturizer comprises propylene glycol, glycerin, hydroxyethyl urea and sodium hyaluronate.
Preferably, the conditioning water further comprises an emulsifier; the emulsifier is PEG-40 hydrogenated castor oil.
Preferably, the conditioning water further comprises a preservative; in the conditioning water, the preservative comprises 0.08-0.12 wt% of methyl hydroxybenzoate, 0.1185-0.158 wt% of bis (hydroxymethyl) imidazolidinyl urea and 0.0015-0.002 wt% of iodopropynyl alcohol butyl carbamate.
Preferably, the conditioning water comprises the following components in percentage by weight: 0.4-0.6% of acne-removing composition A, 0.4-0.6% of acne-removing composition B, 0.14-0.26% of guava fruit extract, 1-2% of nicotinamide, 3.2-4.8% of glycerol, 1.8-2.8% of propylene glycol, 0.7-1.3% of hydroxyethyl urea, 0.014-0.026% of sodium hyaluronate, 0.013-0.027% of PEG-40 hydrogenated castor oil, 0.08-0.12% of methyl hydroxybenzoate, 0.1185-0.158% of bis (hydroxymethyl) imidazolidinyl urea and 0.0015-0.002% of iodopropynyl alcohol butyl carbamate. The conditioning water prepared by the proportion has the effects of deep oil control, inflammation diminishing and acne mark fading.
More preferably, the conditioning water comprises the following components in percentage by weight: 0.5% of acne-removing composition A, 0.5% of acne-removing composition B, 0.2% of guava fruit extract, 1.5% of nicotinamide, 4% of glycerol, 3.21% of propylene glycol, 1% of hydroxyethyl urea, 0.02% of sodium hyaluronate, 0.02% of PEG-40 hydrogenated castor oil, 0.1% of methylparaben, 0.14% of bis (hydroxymethyl) imidazolidinyl urea and 0.00175% of iodopropynyl alcohol butyl carbamate. The water conditioning acne removing effect adopting the formula is optimal.
Besides the specific requirements of the components, other auxiliary materials such as pH regulator, essence, pigment and the like can be added or used in the range of not damaging the effect of the invention, and the ordinary content can be selected by the skilled in the art according to the conventional standard.
The invention has the beneficial effects that: the invention provides acne-removing conditioning water, which is prepared by adding mild plant extract components and matching with basic raw materials, and can open skin pores, maintain the water-oil balance of the skin, improve the hair follicle keratinization of the skin, remove acnes, fade acne marks, repair damaged skin and restore the natural health state of the skin.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Examples 1 to 9
Examples 1 to 9 are examples of the acne-removing conditioning water disclosed by the invention, and the formula of the acne-removing conditioning water disclosed by the examples 1 to 6 is shown in table 1. The formula of the acne-removing conditioning water described in examples 7-9 is shown in table 2. In embodiments 1 to 9, the acne-removing composition a comprises the following components in parts by weight: 15 parts of salvia miltiorrhiza root extract, 3 parts of clove bud extract, 2 parts of scutellaria baicalensis root extract, 2 parts of angelica root extract, 1 part of liquorice root extract and 1 part of centella extract; the acne-removing composition B comprises the following components in parts by weight: 3 parts of oldenlandia diffusa extract, 3 parts of honeysuckle extract and 1 part of Chinese honey locust seed extract.
The preparation method of the acne-removing conditioning water disclosed in embodiments 1-9 comprises the following steps:
s1, adding water, glycerol, hydroxyethyl urea, sodium hyaluronate, guava fruit extract, nicotinamide, methyl hydroxybenzoate and propylene glycol, stirring, heating to 85 deg.C, keeping the temperature for 20 min, and then stirring and cooling to 50 deg.C;
s2, adding bis (hydroxymethyl) imidazolidinyl urea, iodopropynyl butylcarbamate, a composition A capable of solubilizing to be transparent, a composition B capable of removing acne, melaleuca alternifolia leaf oil and PEG-40 hydrogenated castor oil, and stirring uniformly;
and S3, cooling to normal temperature, and discharging after the inspection is qualified to obtain the acne-removing conditioning water.
Table 1 formula of acne removing conditioner water described in examples 1 to 6
Comparative examples 1 and 2
The formulas of the acne-removing conditioning water for the comparative examples 1 and 2 are shown in the table 2. The acne-removing composition B comprises the following components in parts by weight: 3 parts of oldenlandia diffusa extract, 3 parts of honeysuckle extract and 1 part of Chinese honey locust seed extract. The preparation method of the acne-removing conditioning water in comparative examples 1 and 2 is the same as that in examples 1-9.
Table 2 formula of acne removing conditioner water described in examples 7 to 9 and comparative examples 1 and 2
The products of examples 1-9 and comparative examples 1 and 2 are tested to meet the relevant requirements of QB/T1857-.
Example 10
Product safety evaluation (human body skin patch experiment)
Firstly, testing a test article: acne-removing conditioning water prepared in examples 1-9 and comparative examples 1 and 2
Number of test population: 110 people, female
Age: between 12 and 30 years old
Health condition: the skin of the subject is healthy, has no allergic history of the skin disease, and meets the voluntary selection standard of the subject.
Grouping: 11 groups of 10 people each, mean age 25 ± 2 years.
Secondly, a spot pasting method: selecting a qualified spot tester, dripping 0.020 g-0.025 g of a tested object into the spot tester in a closed spot patch test mode, externally applying a special adhesive tape to the back of the tested object, removing the tested object after 24 hours, observing skin reactions after 0.5, 6, 12, 24 and 48 hours after the tested object is removed respectively, and recording the results according to the skin reaction grading standard in the cosmetic hygiene standard.
Thirdly, experimental results: the result of the human body skin patch test shows that: each group of subjects pass the patch test of the acne-removing conditioning water of examples 1-9 and comparative examples 1 and 2, and observe skin reactions at 0.5, 6, 12, 24 and 48 hours, wherein 0 case has adverse skin reactions, which indicates that the acne-removing conditioning water is safe to use.
Example 11
Test of bacteriostatic Effect
First, test materials
1. Test strains: propionibacterium acnes (ATCC 6919).
2. Test samples: storing samples S1, S2, S3, S4, S5, S6, S7, S8, D1 and D2 at 4 ℃ for later use, wherein the proportions of the anti-acne ingredients in S1, S2, S3, S4, S5, S6, S7, S8, D1 and D2 respectively correspond to the proportions of the anti-acne ingredients in examples 1-8 and comparative examples 1 and 2.
3. Culture medium: the pH of the culture medium for the acne propionibacterium acnes is adjusted to 6.6-7.0. Wherein 15g/L of agar is added into the solid culture medium.
Second, test method
1. Preparing and inoculating a bacterial suspension: taking 0.1mL of the frozen and preserved bacterial suspension to be placed in 5mL of propionibacterium acnes liquid culture medium, and culturing for 2d under the anaerobic condition at 37 ℃ to obtain experimental bacterial suspension.
2. Preparing a liquid medicine: s1, S2, S3, S4, S5, S6, S7, S8, D1, and D2 were diluted with physiological saline to test concentration 0.1%, respectively, and then diluted in a gradient. The gradient dilution concentrations of the first test were 100% (sample stock solution), 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%, respectively. The concentration of the second test retest gradient dilution is 10%, 8%, 6%, 4% and 2%, respectively.
3. Preparing bacterial liquid: the bacterial suspension was diluted with Propionibacterium acnes liquid medium to a final bacterial concentration of l06CFU/mL。
4. Culturing and judging results: adding 100 μ L of bacteria solution and 100 μ L of liquid medicine into the micropores, setting negative control without bacteria and normal growth control without liquid medicine, making 3 parallels for each medicine, and taking average value. Anaerobic incubation is carried out at 37 ℃, and the result is observed after 48 hours. Whether turbidity exists or not is judged by naked eyes, and data are read by a direct method. The premise of result judgment is that the growth contrast is good, the blank contrast aseptically grows clearly, and the growth of bacteria in other holes is inhibited along with the increase of the drug concentration gradient.
TABLE 3 results of the first bacteriostatic gradient test
Note: wherein "+" represents the presence of bacteria and "-" represents the absence.
TABLE 4 results of the second bacteriostatic gradient test
Note: wherein "+" represents the presence of bacteria and "-" represents the absence.
5. Results
As can be seen from the results in Table 3, the 0.1% solutions of examples 1-6 and 8, when diluted to a concentration of 12.5% or more, have a good inhibitory effect on Propionibacterium acnes, whereas the 25% dilution of example 7 and above can achieve the effect, and the comparative example 1 requires a concentration of 50% or more. The results in table 4 show that the bacteriostatic concentration of the solutions in examples 1 to 6 can be achieved by 10% of the diluent, and the bacteriostatic concentration of the solution in example 1 can achieve the bacteriostatic effect by 6% of the diluent. According to the results, the minimal addition of the acne-removing component is about 0.01%, so that the effect of inhibiting propionibacterium acnes can be basically achieved, and when the acne-removing component is jointly used by the acne-removing composition A, the acne-removing composition B and the guava fruit extract, the antibacterial effect is stronger than that when one or two of the acne-removing composition A, the acne-removing composition B and the guava fruit extract are used.
Example 12
Clinical tests were carried out on the conditioned water described in examples 1 to 9 and comparative examples 1 and 2, specifically as follows:
the number of people: 110 people, divided into 11 groups of 10 people, the proportion of the people to the men is 1:1, and the face has acne
Time: 21 days
The part: face part
Sample preparation: conditioned Water as described in examples 1-9 and comparative example 1
Evaluation: evaluation and photographing according to the GAGS scoring method were performed (photograph not shown):
the GAGS scoring method is a Global Acid Grading System (GAGS) of an Acne comprehensive Grading System proposed by Doshi et al in 1997, is a scoring method, and has the characteristics of accuracy, strong consistency, quickness, good overall evaluation effect and the like. The method specifically comprises the following steps: according to the density, distribution and approximate area of the pilosebaceous unit, the good hair part of the acne is divided into 6 areas: zone i, forehead, zone ii: right cheek, zone iii: left cheek, region iv: nose, chin zone v, zone vi: chest and upper back. The scores of factors in the I, II and III zones are 2, the scores of factors in the IV and V zones are 1, the score of factors in the VI zone is 3, and the score of the skin loss of each zone is (the principle is that the local most serious skin loss determines the score of the zone): 0 is no skin damage; 1 is more than or equal to 1 acne; 2 or more than 1 pimple; 3, more than or equal to 1 abscess; 4 is more than or equal to 1 node. The total score of each subarea is factor score multiplied by skin damage score, and the sum of the total scores of different subareas is the comprehensive score.
The evaluation results are shown in Table 5.
TABLE 5 GAGS score evaluation results for conditioned Water as described in examples 1-9 and comparative example 1
| Group of | Before use | 3 days | 7 days | 14 days | 21 days |
| Example 1 | 18.8 | 15.3* | 12.5** | 10.8** | 7.3** |
| Example 2 | 18.4 | 16.0* | 15.5** | 13.5** | 10.9** |
| Practice ofExample 3 | 18.8 | 17.0* | 15.3** | 13.5** | 11.5** |
| Example 4 | 19.0 | 16.3* | 15.0** | 12.3** | 9.3** |
| Example 5 | 18.6 | 16.6* | 14.1** | 12.1** | 9.9** |
| Example 6 | 17.5 | 15.5* | 13.0** | 12.9** | 10.6** |
| Example 7 | 17.5 | 15.5* | 14.7* | 13.0** | 12.3** |
| Example 8 | 18.4 | 16.3* | 14.8* | 13.5** | 12.6** |
| Example 9 | 18.4 | 16.5* | 13.6** | 12.2** | 11.6** |
| Comparative example 1 | 18.0 | 16.4 | 15.5* | 14.9** | 13.6** |
| Comparative example 2 | 18.2 | 17.6 | 16.5* | 16.0* | 15.2** |
P < 0.05VS before use, P < 0.01VS before use
As can be seen from Table 5, the conditioned water described in examples 1-9 showed a significant decrease in acne score after 3 days (P < 0.05), a significant decrease at 7, 14 and 21 days, and statistical significance (P < 0.01) compared to pre-application. As can be seen from the table, compared with example 1, examples 4 to 6 have higher comprehensive scores after 21 days of use, which indicates that the acne-removing compositions a and B need to be in a certain proportion to exert better acne-removing effects; compared with example 1, the acne removing effects of examples 7 and 8 and comparative examples 1 and 2 are slightly poor, which shows that the acne removing effect of the acne removing composition A, the acne removing composition B and the guava fruit extract is better, the acne removing effect of example 9 is worse than that of example 1, and shows that nicotinamide can play a certain auxiliary acne removing effect together.
Example 13
Evaluation of product Effect
Firstly, testing a test article: acne-removing conditioning water prepared in examples 1 to 3
Second, the tested population
Sex number: 90 people with a male to female ratio of about 1:1
Age: between 12 and 30 years old
Health condition: the skin of the subject is healthy, has no allergic history of the skin disease, and meets the voluntary selection standard of the subject.
Grouping: divided into 3 groups of 30 persons each, with a mean age of 25 ± 2 years.
Thirdly, a testing method: the acne-removing conditioning water prepared in the examples 1-3 is used for observing and feeling the using effect. The using method comprises the following steps: after the face of a subject is cleaned, a proper amount of acne-removing conditioning water is uniformly smeared on the face and is massaged until the acne-removing conditioning water is absorbed. The medicine is taken once a day, morning and evening, and is used for one month, and is checked at least once a week to know whether systemic and local adverse reactions exist, and the result is recorded in detail.
The test evaluation results are shown in tables 6-8.
Table 6 example 1 summary of trial (one month) feedback of anti-acne treatment water
Table 7 example 2 summary of trial (one month) feedback of anti-acne treatment water
Table 8 example 3 summary of trial (one month) feedback of anti-acne conditioner water
As can be seen from tables 6 to 8, the acne-removing conditioning lotion disclosed by the embodiments 1 to 3 is widely popular and approved by the testee, and the testee shows that the acne-removing conditioning lotion disclosed by the invention is mild in texture, can astringe pores, soothe skin, adjust the water-oil balance of the skin, and deeply repair and condition the acne skin. The acne-removing conditioning water prepared in the example 1 has the highest acceptance degree in the examples 1 to 3. Meanwhile, no allergy phenomenon occurs in all the subjects, and the conditions of skin itch, stabbing pain, red swelling and the like do not occur. Therefore, the acne-removing and water-temperature-regulating cream is safe and can be used for a long time.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (5)
1. An acne-removing conditioning water is characterized by comprising an acne-removing composition A; the weight percentage content of the acne-removing composition A in the acne-removing conditioning water is 0.5%; the acne-removing composition A comprises the following components in parts by weight: 15 parts of salvia miltiorrhiza root extract, 3 parts of clove bud extract, 2 parts of scutellaria baicalensis root extract, 2 parts of angelica root extract, 1 part of liquorice root extract and 1 part of centella extract; the conditioning water also comprises an acne-removing composition B; the weight percentage content of the acne-removing composition B in the acne-removing conditioning water is 0.5%; the acne-removing composition B comprises the following components in parts by weight: 3 parts of oldenlandia diffusa extract, 3 parts of honeysuckle extract and 1 part of Chinese honey locust seed extract; the conditioning water also comprises 0.2% of guava fruit extract; the conditioning water further comprises a skin-activating ingredient; the skin-active ingredient comprises niacinamide; the weight percentage of the nicotinamide in the conditioning water is 1.5%.
2. The acne-removing conditioning water according to claim 1, further comprising a humectant; the moisturizer comprises propylene glycol, glycerin, hydroxyethyl urea and sodium hyaluronate.
3. The acne-removing conditioning water according to claim 1, further comprising a preservative; in the conditioning water, the preservative comprises 0.08-0.12 wt% of methyl hydroxybenzoate, 0.1185-0.158 wt% of bis (hydroxymethyl) imidazolidinyl urea and 0.0015-0.002 wt% of iodopropynyl alcohol butyl carbamate.
4. The acne-removing conditioning water according to claim 1, wherein the conditioning water comprises the following components in percentage by weight: 0.5% of acne-removing composition A, 0.5% of acne-removing composition B, 0.2% of guava fruit extract, 1.5% of nicotinamide, 3.2-4.8% of glycerol, 1.8-2.8% of propylene glycol, 0.7-1.3% of hydroxyethyl urea, 0.014-0.026% of sodium hyaluronate, 0.013-0.027% of PEG-40 hydrogenated castor oil, 0.08-0.12% of methylparaben, 0.1185-0.158% of bis (hydroxymethyl) imidazolidinyl urea and 0.0015-0.002% of iodopropynyl alcohol butyl carbamate.
5. The acne-removing conditioning water according to claim 1, wherein the conditioning water comprises the following components in percentage by weight: 0.5% of acne-removing composition A, 0.5% of acne-removing composition B, 0.2% of guava fruit extract, 1.5% of nicotinamide, 4% of glycerol, 3.21% of propylene glycol, 1% of hydroxyethyl urea, 0.02% of sodium hyaluronate, 0.02% of PEG-40 hydrogenated castor oil, 0.1% of methylparaben, 0.14% of bis (hydroxymethyl) imidazolidinyl urea and 0.00175% of iodopropynyl alcohol butyl carbamate.
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| CN109260075B true CN109260075B (en) | 2021-06-15 |
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| CN110075046B (en) * | 2019-05-29 | 2021-06-18 | 广州睿晞生化科技有限公司 | Composition capable of removing acne and trace |
| CN112107523A (en) * | 2019-06-19 | 2020-12-22 | 东莞圣幸健康科技有限公司 | Moistening acne-removing composition and moistening acne-removing mask |
| CN110368348A (en) * | 2019-08-29 | 2019-10-25 | 广州重生化妆品实业有限公司 | A kind of formula of acne removal stock liquid and preparation method thereof |
| CN114404340B (en) * | 2022-03-10 | 2023-12-19 | 稳健医疗用品股份有限公司 | Plant acne-removing composition and application thereof |
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