CN108295022B - Acne-removing composition and preparation method thereof - Google Patents
Acne-removing composition and preparation method thereof Download PDFInfo
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- 238000003756 stirring Methods 0.000 claims description 35
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of cosmetic preparation, and particularly relates to an acne-removing composition and a preparation method thereof, wherein the acne-removing composition comprises the following components in parts by weight: 5-15 parts of a humectant; 0.3-1 part of solubilizer; 0.5-1.2 parts of preservative; 0.01-0.1 parts of chelating agent; 0.5-1 part of an anti-allergy agent; 0.2-0.5 part of water phase thickening agent; 0.01-0.1 part of pH value regulator; 3-5 parts of a sweet-rooted iris root extract; 5-8 parts of aloe vera extract; 0.1-0.5 parts of melaleuca alternifolia leaf oil; 1-2 parts of phellodendron amurense bark extract; 0.5-1 parts of royal jelly extract; 60-80 parts of deionized water. The acne removing composition disclosed by the invention has synergistic components, has the effects of continuously controlling oil and mildly removing acnes, can inhibit the growth of facial acnes, inhibit the formation of acnes, improve acne marks and rough skin, gradually deepen and fade the acne marks, and promote the renewal of skin cuticle; has the effects of diminishing inflammation, sterilizing, resisting allergy, balancing oil secretion, and relieving and repairing acne marks.
Description
Technical Field
The invention belongs to the technical field of preparation of daily cosmetics, and particularly relates to a composition with an acne removing effect and a preparation method of a product containing the composition.
Technical Field
Acne, commonly known as whelk, is an inflammatory lesion that occurs in the pilosebaceous glands and their surrounding tissues. The pathogenesis of acne vulgaris is as follows: facial sebum secretion is increased, resulting in hyperkeratosis of hair follicles and sebaceous gland ducts. The hyperkeratotic cells combine with sebum, which deposits on hair follicles to form fatty granules, which are broken down by propionibacterium acnes in the hair follicles to produce free fatty acids, causing inflammation to form acne. From the pathogenesis of acne, propionibacterium acnes (Propionibacterium acnes) is a key factor and an important condition for the final formation of acne, and if certain active ingredients can be added in the formula design of cosmetics to effectively inhibit or kill the propionibacterium acnes, the expected acne removing effect can be achieved.
Acne occurs more commonly in all types of people, especially young people. In recent years, the incidence of the acne in China is on the rise year by year, and the number of the acne patients accounts for more than one third of the total number of the young people. The clinical manifestations are marked by the polymorphic skin lesions of face, such as acne, papule, pustule, and nodule. Whelk is bred due to hormone hyperactivity, emotional disorder, environmental pollution, irregular diet, poor sleep, stress and the like in the adolescence.
The existing acne removing methods are various, and 1, like a laser acne treating method, the method can rapidly destroy the propionibacterium acnes, effectively inhibit bacterial reproduction, and eliminate stimulation and destruction on tissues, but the laser acne treating method has too strong effect and high cost, and only a physical method destroys the acnes and cannot radically remove the acnes; 2. the tartaric acid therapy has a certain inhibiting effect, but has large stimulation, strong side effect and high cost; 3. the western medicines such as antibiotics and the like are used for treating acne, the effect is quick, but the drug resistance problem occurs in the using process and the skin-dependent dermatitis is formed after long-term use.
Acne, although a skin disorder, affects the appearance of the patient, as well as the mind and social interaction of the patient. Therefore, a product which is effective in conditioning acne muscle, inhibiting acne regeneration, and smoothing acne pits, mild, non-irritating, safe and effective is needed to be developed.
Disclosure of Invention
The invention aims to provide a composition with an acne removing effect, and the composition can effectively condition acne muscles, inhibit acne regeneration, smooth acne pits and fade acne marks.
The composition with the acne removing effect is prepared from various Chinese herbal medicine extracts and a plurality of compositions which have the effects of inhibiting skin grease secretion, stimulating the growth of epithelial cells, promoting wound healing, diminishing inflammation, moisturizing and removing acne. The acne-removing composition is a pure natural product, can effectively treat acne, and is mild and free of side effects.
In order to solve the technical scheme, the technical scheme provided by the invention is as follows:
the acne-removing composition comprises the following components in parts by weight: 5-15 parts of a humectant; 0.3-1 part of solubilizer; 0.5-1.2 parts of preservative; 0.01-0.1 parts of chelating agent; 0.5-1 part of an anti-allergy agent; 0.2-0.5 part of water phase thickening agent; 0.01-0.1 part of pH value regulator; 3-5 parts of a sweet-rooted iris root extract; 5-8 parts of aloe vera extract; 0.1-0.5 parts of melaleuca alternifolia leaf oil; 1-2 parts of phellodendron amurense bark extract; 0.5-1 parts of royal jelly extract; 60-80 parts of deionized water.
The humectant is a mixture of glyceryl polyether-26, betaine, 1, 2-pentanediol and sodium hyaluronate.
The solubilizer is PEG-40 hydrogenated castor oil.
The chelating agent is disodium EDTA.
The preservative is a mixture of phenoxyethanol and ethylhexyl glycerin.
The anti-allergic agent is a mixture of butanediol, 1, 2-pentanediol and hydroxyphenylpropionamide benzoic acid.
The pH value regulator is sodium hydroxide.
The water phase thickening agent is carbomer.
The preparation method of the acne-removing composition comprises the following steps:
step one, adding deionized water, a humectant, a chelating agent and an aqueous phase thickener into an aqueous phase pot, stirring at 75-85 ℃ until the materials are dispersed, pumping into an emulsifying pot, and homogenizing;
step two, pre-dissolving the pH neutralizing agent by using deionized water to obtain a pre-prepared solution I; adding the preservative and the anti-allergic agent into a container, and uniformly stirring and dispersing to obtain a pre-prepared solution II;
step three, adding the first preparation solution into an emulsifying pot, preserving heat, beginning to cool after stirring, adding the second preparation solution, the Iris communis root extract, the Aloe vera extract, the cortex phellodendri bark extract, the royal jelly extract and the anti-allergy agent, and stirring until the mixture is uniformly dispersed;
and step four, adding a mixture of PEG-40 hydrogenated castor oil and melaleuca alternifolia leaf oil which are uniformly dispersed in advance, and stirring the mixture until the mixture is uniform to obtain the composition.
The stirring speed of the stirring is 40-50 revolutions per minute.
In the components of the invention, the iris extract has the functions of astringency and anti-inflammation,
the using method of the invention is as follows:
after the face is simply cleaned, a proper amount of material body is extruded out, the mixture is applied on the skin part with acnes by spot application, and the mixture is gently massaged until the mixture is absorbed, namely twice in the morning and at night.
Compared with the prior art, the invention has the advantages that:
(1) the acne-removing composition disclosed by the invention is composed of various plant extracts, is natural and non-irritant, and has the effects of inhibiting skin grease secretion, stimulating the growth of epithelial cells, promoting wound healing and diminishing inflammation. The essential oil can supplement the essential oil needed by the skin in time, promote the skin to be repaired, tighten the skin, smooth acne pits, reduce acne marks, improve the skin and inhibit the acne from being regenerated.
(2) The acne removing essence disclosed by the invention is mild in formula, free of irritation, easy to absorb, non-greasy, safe and efficient, and can be used for quickly permeating into skin in cooperation with the acne removing composition disclosed by the invention, so that the aims of safely and efficiently removing acnes, repairing skin and inhibiting acnes from regenerating are fulfilled; meanwhile, the acne-removing essence disclosed by the invention is easy to obtain raw materials, simple in preparation process, easy to control conditions and capable of being popularized and applied.
The invention has the following beneficial effects: the acne removing composition disclosed by the invention has synergistic components, has the effects of continuously controlling oil and mildly removing acnes, can inhibit the growth of facial acnes, inhibit the formation of acnes, improve acne marks and rough skin, gradually deepen and fade the acne marks, and promote the renewal of skin cuticle; has the effects of diminishing inflammation, sterilizing, resisting allergy, balancing oil secretion, and relieving and repairing acne marks.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the description is intended to be exemplary only, and is not intended to limit the scope of the present invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.
The IRIS pallida (IRIS FLORENTINA) root extract is an IRIS pallida (IRIS FLORENTINA) root extract purchased from lacun trade company with the product number of 17071501;
the Aloe vera (Aloe Barbadensis) extractive solution is Aloe vera (Aloe Barbadensis) extractive solution from Ostrin chemical Limited, Guangzhou, cat # 6137008;
the MELALEUCA ALTERNIFOLIA (MELALEUCA ALTERNIFOLIA) leaf oil is obtained from Hugezeal Bio-chemical Australia, and has a product number of 28608691;
the cortex Phellodendri (PHELLODENDRON AMURENSE) bark extract is cortex Phellodendri (PHELLODENDRON AMURENSE) bark extract from Auxue chemical Co., Ltd, Guangzhou, cat # 07136;
the royal jelly extract is a royal jelly extract purchased from Guangzhou Olympic trade company Limited, and the product number is 33078P;
example 1
The components are as follows: 7g of glyceryl polyether-26, 1g of betaine, 2g of 1, 2-pentanediol, 1g of sodium hyaluronate, 0.05g of disodium EDTA, 0.3g of carbomer, 0.5g of phenoxyethanol, 0.3g of ethylhexylglycerin, 0.2g of butanediol, 0.1g of 1, 2-pentanediol, 0.2g of hydroxyphenylpropionamide benzoic acid, 0.075g of sodium hydroxide, 0.4g of PEG-40 hydrogenated castor oil, 3g of Iris pallida root extract, 5g of Aloe barbadensis extract, 0.15g of melaleuca alternifolia leaf oil, 1g of Berberis bark extract, 1g of Royal jelly extract, and 60g of deionized water.
The preparation method comprises the following steps:
step one, adding deionized water, glyceryl polyether-26, betaine, 1, 2-pentanediol, sodium hyaluronate, EDTA disodium and carbomer into a water phase pot, heating to 75-85 ℃ while stirring, stirring until the materials are completely dispersed, pumping into an emulsifying pot, starting homogenizing for 5-10 minutes (3000 revolutions per minute) until the materials are uniformly dispersed without particles (after scraping the pot, homogenizing at the same homogenizing speed for 1 minute), and stirring and defoaming in a vacuum state;
step two, pre-dissolving sodium hydroxide by using deionized water to obtain a pre-prepared solution I; adding phenoxyethanol, ethylhexyl glycerol and 1, 2-pentanediol into a container, and uniformly stirring and dispersing to obtain a pre-configured liquid II;
step three, adding the first preparation liquid after defoaming completely in an emulsifying pot, keeping the temperature and stirring for 15min, then cooling, adding the second preparation liquid, the Iris pallida root extract, the Aloe barbadensis extract, the cortex phellodendri bark extract, the royal jelly extract, butanediol and hydroxyphenylpropionamide benzoic acid at 45 ℃, and stirring until the mixture is completely and uniformly dispersed;
and step four, adding a mixture of PEG-40 hydrogenated castor oil and melaleuca alternifolia leaf oil which are uniformly dispersed in advance, and stirring the mixture until the mixture is uniform to obtain the composition.
Example 2
The components are as follows: 11g of glyceryl polyether-26, 1g of betaine, 1g of 1, 2-pentanediol, 1g of sodium hyaluronate, 0.05g of disodium EDTA, 0.15g of carbomer, 0.8g of phenoxyethanol, 0.4g of ethylhexylglycerin, 0.5g of butanediol, 0.2g of 1, 2-pentanediol, 0.3g of hydroxyphenylpropionamide benzoic acid, 0.03g of sodium hydroxide, 0.4g of PEG-40 hydrogenated castor oil, 5g of Iris pallida root extract, 8g of Aloe barbadensis extract, 0.5g of melaleuca alternifolia leaf oil, 2g of Berberis bark extract, 0.5g of Royal jelly extract, and 63g of deionized water.
The preparation method comprises the following steps:
step one, adding deionized water, glyceryl polyether-26, betaine, 1, 2-pentanediol, sodium hyaluronate, EDTA disodium and carbomer into a water phase pot, heating to 75-85 ℃ while stirring, stirring until the materials are completely dispersed, pumping into an emulsifying pot, starting homogenizing for 5-10 minutes (3000 revolutions per minute) until the materials are uniformly dispersed without particles (after scraping the pot, homogenizing at the same homogenizing speed for 1 minute), and stirring and defoaming in a vacuum state;
step two, pre-dissolving sodium hydroxide by using deionized water to obtain a pre-prepared solution I; adding phenoxyethanol, ethylhexyl glycerol and 1, 2-pentanediol into a container, and uniformly stirring and dispersing to obtain a pre-configured liquid II;
step three, adding the first preparation liquid after defoaming completely in an emulsifying pot, keeping the temperature and stirring for 15min, then cooling, adding the second preparation liquid, the Iris pallida root extract, the Aloe barbadensis extract, the cortex phellodendri bark extract, the royal jelly extract, butanediol and hydroxyphenylpropionamide benzoic acid at 45 ℃, and stirring until the mixture is completely and uniformly dispersed;
and step four, adding a mixture of PEG-40 hydrogenated castor oil and melaleuca alternifolia leaf oil which are uniformly dispersed in advance, and stirring the mixture until the mixture is uniform to obtain the composition.
Example 3
The components are as follows: 3g of glyceryl polyether-26, 4g of betaine, 2g of 1, 2-pentanediol, 3g of sodium hyaluronate, 0.05g of disodium EDTA, 0.15g of carbomer, 0.2g of phenoxyethanol, 0.6g of ethylhexylglycerin, 0.3g of butanediol, 0.05g of 1, 2-pentanediol, 0.15g of hydroxyphenylpropionamide benzoic acid, 0.03gpH value regulator, 0.4g of PEG-40 hydrogenated castor oil, 1.5g of Iris pallida root extract, 2g of Aloe barbadensis extract, 0.05g of melaleuca alternifolia leaf oil, 0.1g of phellodendron amurense bark extract, 0.5g of royal jelly extract, and the balance of water.
The preparation method comprises the following steps:
step one, adding deionized water, glyceryl polyether-26, betaine, 1, 2-pentanediol, sodium hyaluronate, EDTA disodium and carbomer into a water phase pot, heating to 75-85 ℃ while stirring, stirring until the materials are completely dispersed, pumping into an emulsifying pot, starting homogenizing for 5-10 minutes (3000 revolutions per minute) until the materials are uniformly dispersed without particles (after scraping the pot, homogenizing at the same homogenizing speed for 1 minute), and stirring and defoaming in a vacuum state;
step two, pre-dissolving sodium hydroxide by using deionized water to obtain a pre-prepared solution I; adding phenoxyethanol, ethylhexyl glycerol and 1, 2-pentanediol into a container, and uniformly stirring and dispersing to obtain a pre-configured liquid II;
step three, adding the first preparation liquid after defoaming completely in an emulsifying pot, keeping the temperature and stirring for 15min, then cooling, adding the second preparation liquid, the Iris pallida root extract, the Aloe barbadensis extract, the cortex phellodendri bark extract, the royal jelly extract, butanediol and hydroxyphenylpropionamide benzoic acid at 45 ℃, and stirring until the mixture is completely and uniformly dispersed;
and step four, adding a mixture of PEG-40 hydrogenated castor oil and melaleuca alternifolia leaf oil which are uniformly dispersed in advance, and stirring the mixture until the mixture is uniform to obtain the composition.
Test example-acne removing efficacy test method and test result
The test method briefly describes: propionibacterium acnes bacteriostasis test (cup dish method)
Preparing a double-layer plate (the lower layer is 10-15 ml of culture medium, the upper layer is 5ml of culture medium containing propionibacterium acnes) containing propionibacterium acnes (ATCC11827), wherein the bacterial content of the plate is 104-105 CFU/plate, after the plate is cooled, vertically placing 2 Oxford cups on the surface of each plate, wherein the distance between every two Oxford cups is not less than 24mm, and the distance between the center of each Oxford cup and the edge of the plate is not less than 15 mm. 200ul of the tested acne-removing composition was added to the Oxford cup, incubated at 36 + -1 deg.C for 24 hours under anaerobic conditions, and the zone diameter was measured with a ruler (the result was the average of two replicates). The results are shown in Table 1:
TABLE 1 evaluation criteria for acne-removing efficacy
| Serial number | Acne removing effect | Diameter/mm of bacteriostatic circle |
| 1 | Invalidation | D<10 |
| 2 | Low efficiency | 10≤D<15 |
| 3 | Middle effect | 15≤D<20 |
| 4 | High efficiency | ≥20 |
Table 2 sample acne treatment efficacy test results
| Sample name | Diameter/mm of bacteriostatic circle | Acne removing effect |
| Example 1 | 30 | High efficiency |
| Example 2 | 18 | Middle effect |
| Example 3 | 10 | Low efficiency |
In order to eliminate the influence of other preservatives on the antibacterial effect, no preservative is added into the sample for the acne treatment efficacy test. Test results show that the acne-removing composition has a good effect of inhibiting propionibacterium acnes, so that the acne-removing composition has a good acne-removing effect.
Test example two product safety evaluation (human body skin patch experiment)
Test products: example 1 to 3 acne removing composition
Number of test population: 30, female
Age: between 20 and 50 years old
Health condition: the skin of the subject is healthy, has no allergic history of the skin disease, and meets the voluntary selection standard of the subject.
Grouping: 3 groups of 10 people each, mean age 28 ± 2 years.
The spot pasting method comprises the following steps: selecting a qualified spot tester, dripping 0.020 g-0.025 g of a tested object into the spot tester in a closed spot patch test mode, externally applying a special adhesive tape to the back of the tested object, removing the tested object after 24 hours, observing skin reactions after 0.5, 6, 12, 24 and 48 hours after the tested object is removed respectively, and recording the results according to the skin reaction grading standard in the cosmetic hygiene standard.
The experimental results are as follows: the result of the human body skin patch test shows that: each group of subjects pass the spot test of the acne-removing composition of examples 1-3, and observe skin reactions at 0.5, 6, 12, 24 and 48 hours, wherein 0 cases of the subjects have adverse skin reactions, which indicates that the acne-removing composition is safe to use.
Test example three stability tests of acne removing composition
The acne-removing composition of example 1 was subjected to performance index tests, and the test results were as follows:
1. heat resistance stability test (40 ℃ C.. times.30 days): qualified;
2. cold resistance stability test (-10 ℃ C.. times.30 days): and (4) passing.
The third test example shows that the acne-removing composition of example 1 has good stability.
Test example four product Effect evaluation
And (3) testing a sample: example 1 to 3 acne removing composition
The test population: between 20 and 40 years of age, 15 women; 10 men
Skin condition: the face has obvious acne and pox, has no allergic history of dermatosis, and meets the voluntary selection standard of a subject.
Grouping: divided into 5 groups of 5 persons each, female 3 persons, male 2 persons.
The test method comprises the following steps: applying appropriate amount of test sample on cleaned affected part, 2 times per day, 1 time each in the morning and evening, and trying for 2 weeks; subjects maintained good working and resting time and eating habits during the trial period. After 2 weeks, the feedback of the subjects was counted, and the specific results are shown in the following table.
Table 3 test results for anti-acne compositions
As can be seen from table 3, the acne removing compositions of examples 1 to 3 of the present invention were approved by almost all the subjects, and had good effects of removing acne and acne marks, and simultaneously could repair acne muscle, i.e., improve the red and swollen, rough, and exuberant oil secretion of skin, and reduce the regeneration of acne, wherein the acne removing composition of example 1 had the highest acceptance. Meanwhile, no allergy phenomenon occurs in all the subjects, and the conditions of skin itch, stabbing pain, red swelling and the like do not occur.
Claims (1)
1. An acne-removing composition is characterized by comprising the following components: 7g of glyceryl polyether-26, 1g of betaine, 2g of 1, 2-pentanediol, 1g of sodium hyaluronate, 0.05g of disodium EDTA, 0.3g of carbomer, 0.5g of phenoxyethanol, 0.3g of ethylhexylglycerin, 0.2g of butanediol, 0.1g of 1, 2-pentanediol, 0.2g of hydroxyphenylpropionamide benzoic acid, 0.075g of sodium hydroxide, 0.4g of PEG-40 hydrogenated castor oil, 3g of Iris pallida root extract, 5g of Aloe barbadensis extract, 0.15g of melaleuca alternifolia leaf oil, 1g of phellodendron amurense bark extract, 1g of royal jelly extract, 60g of deionized water;
the preparation method comprises the following steps:
step one, adding deionized water, glyceryl polyether-26, betaine, 1, 2-pentanediol, sodium hyaluronate, EDTA disodium and carbomer into a water phase pot, heating to 75-85 ℃ while stirring, stirring until the materials are completely dispersed, pumping into an emulsifying pot, starting homogenizing for 5-10 minutes at 3000 rpm; until the particles are uniformly dispersed, scraping the pot, homogenizing at the same homogenizing speed for 1 minute; stirring and defoaming in a vacuum state;
step two, pre-dissolving sodium hydroxide by using deionized water to obtain a pre-prepared solution I; adding phenoxyethanol, ethylhexyl glycerol and 1, 2-pentanediol into a container, and uniformly stirring and dispersing to obtain a pre-configured liquid II;
step three, adding the first preparation liquid after defoaming completely in an emulsifying pot, keeping the temperature and stirring for 15min, then cooling, adding the second preparation liquid, the Iris pallida root extract, the Aloe barbadensis extract, the cortex phellodendri bark extract, the royal jelly extract, butanediol and hydroxyphenylpropionamide benzoic acid at 45 ℃, and stirring until the mixture is completely and uniformly dispersed;
and step four, adding a mixture of PEG-40 hydrogenated castor oil and melaleuca alternifolia leaf oil which are uniformly dispersed in advance, and stirring the mixture until the mixture is uniform to obtain the composition.
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