CN111956575A - Skin whitening, anti-aging and moisturizing skin care product containing aloe active substances and preparation method thereof - Google Patents
Skin whitening, anti-aging and moisturizing skin care product containing aloe active substances and preparation method thereof Download PDFInfo
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- CN111956575A CN111956575A CN202010885894.2A CN202010885894A CN111956575A CN 111956575 A CN111956575 A CN 111956575A CN 202010885894 A CN202010885894 A CN 202010885894A CN 111956575 A CN111956575 A CN 111956575A
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- phase
- aloe
- raw materials
- skin
- care product
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The invention provides a whitening, anti-aging and moisturizing skin care product containing aloe active substances and a preparation method thereof, wherein the whitening, anti-aging and moisturizing skin care product comprises a phase A, a phase B and a phase C, wherein the phase A is prepared from the following raw materials in percentage by mass: 8% of propylene glycol; 26, 5% of glyceryl polyether; 5% of glycerol; carbomer, 0.2%; 0.15% of hydroxyethyl cellulose; 0.1% of dipotassium glycyrrhizinate; disodium EDTA, 0.05%; 0.05 percent of sodium hyaluronate; 0.15 percent of methyl hydroxybenzoate and deionized water are added to 100 percent; the phase B comprises the following raw materials in percentage by mass: beta-glucan, 0.1%; panthenol, 0.1%; aloe active, 2%; aminomethyl propanol, 0.15%; 0.3 percent of phenoxyethanol; phase C comprises 0.05% essence, 0.3% PEG-35 oleum ricini; the phase A has the functions of moisturizing, anti-allergy and relieving, the phase B is used for conditioning the skin and brightening the skin color, and the phase C is used for improving the smell of the product and improving the overall use quality.
Description
Technical Field
The invention relates to the technical field of skin care products, in particular to a whitening, anti-aging and moisturizing skin care product containing aloe active substances and a preparation method thereof.
Background
Aloe contains aloe-emodin, aloe-emodin glycoside, aloe polysaccharide, aloe-emodin phenol, organic acid, amino acid, vitamins and enzyme. Aloe has been used in the treatment of skin diseases since ancient times, and fresh leaves are mashed to apply aloe juice to the affected part for treating burn, scald, and mosquito bite. Mixing Aloe juice and flour to obtain paste, applying to affected part, and wrapping with cloth for treating injury, sprain and sore. Along with the development of the times, the aloe is applied to cosmetics in a large quantity, and has the effects of sun screening, moisture preservation, inflammation diminishing, aging resistance and the like. The invention utilizes the special properties of the aloe vera extract to prepare the whitening, anti-aging and moisturizing skin care product containing the aloe active substances by adopting scientific and rigorous process flow.
Disclosure of Invention
The invention aims to provide the aloe skin care product which is safe to use, effectively improves the skin condition, moisturizes and beautifies and has the anti-aging effect.
The invention also discloses a preparation method of the aloe skin care product, which has wide raw material source and convenient preparation and processing.
In order to achieve the purpose, the invention adopts the technical scheme that: a skin care product containing Aloe active substance with skin whitening, antiaging, and moisturizing effects comprises phase A, phase B, and phase C;
the phase A consists of the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
the phase C comprises the following raw materials in percentage by mass:
0.05% of C-phase essence
PEG-35 Castor oil 0.3%
Wherein, the aloe active matter in the phase B consists of the following raw materials in percentage by mass:
preferably, the aloe active in phase B consists of the following raw materials in mass percent:
further, the preparation method of the whitening, anti-aging and moisturizing skin care product containing the aloe active matter comprises the following steps:
(1) sequentially adding the phase A raw materials into a main pot, starting stirring, uniformly dispersing until no insoluble substances exist, starting heating, heating to 80-85 ℃, preserving heat for 20min, and starting cooling;
(2) preparing aloe active substance, cooling to 45 deg.C, sequentially adding phase B raw materials, and stirring until no insoluble substance exists;
(3) premixing the phase C raw materials, stirring to be uniform and transparent, then slowly adding the mixture into a main pot, stirring to be uniform, cooling to 38 ℃, using filter cloth with more than 400 meshes, filtering and discharging.
The preparation method of the aloe active substance comprises the following steps:
(1) weighing the raw materials according to the mass percent, putting propylene glycol into a first beaker, adding PE9010, and uniformly stirring to obtain a solution 1;
(2) adding Aloe vera extract into solution 1, slowly stirring with glass rod to completely disperse and dissolve Aloe vera extract to obtain solution 2;
(3) adding Aloe Barbadensis Miller leaf water into solution 2, slowly stirring with glass rod, and filtering to obtain Aloe active substance.
The invention has the beneficial effects that:
1. the aloe skin care product provided by the invention is obtained by multiple experiments according to the most scientific and effective dosage proportion, each component plays a role in the formula fully, and the components react with each other, so that the formula effect is more reasonable and effective, wherein the phase A has the effects of moisturizing, anti-allergy, relieving and stabilizing the product quality, the phase B is used for conditioning the skin, brightening the skin color, resisting aging, removing wrinkles and preserving moisture, and the phase C is used for improving the product smell and improving the overall use quality.
The propylene glycol has good viscosity and hygroscopicity, has good intersolubility with the phase C, can help active ingredients to permeate, also helps the antiseptic ability, belongs to a small molecule moisture retention component, and can retain water in the horny layer;
the glyceryl polyether-26 is an excellent humectant and lubricant, can keep stable property in the whole pH value range adopted by cosmetics, can form a double-layer moisturizing film, effectively locks moisture, has good compatibility with cationic, nonionic and anionic surfactants, has no greasy feeling, and has smooth and fine touch feeling;
the glycerin molecules can form hydrogen bonds with water molecules, so that the glycerin has water absorption, a layer of film is formed on the skin, the effects of isolating air and preventing water evaporation are achieved, the water in the air can be absorbed, the skin can be kept soft and elastic, the skin is not damaged by dust, climate and the like and is dry, and the effects of moisturizing and preventing the skin from being frostbitten are achieved;
the sodium hyaluronate increases water absorption to form a protective barrier to reduce water loss and increase luster, can prevent chapped skin and wrinkles, can absorb water from the air to the skin to help the skin to keep water, and helps to recover and maintain a healthy barrier to prevent water loss through skin, and can replace water and hyaluronic acid which naturally exist in the skin but slowly lose, so that the skin texture is smooth and fine, the sodium hyaluronate can generate transient and instant plump visual feeling on the skin, the texture is light, moist luster is brought to the skin, and thick and greasy feeling can not be left;
carbomer has good transparency and obvious shear thinning characteristic, can provide good suspension capacity, protect skin, reduce irritant substances and prevent various allergic symptoms, can enhance the resistance of human skin to ultraviolet rays after being smeared on the surface layer of human skin, can reduce the damage of the ultraviolet rays to the human skin, and has obvious maintenance efficacy on the human skin;
the hydroxyethyl cellulose protects moisture and colloid, and has better flow regulation property when being used together with other components;
the dipotassium glycyrrhizinate is prepared by taking liquorice as a raw material, extracting the liquorice with water, and then adding potassium hydroxide or carbonate for neutralization, has stable chemical properties and good solubility and emulsibility, has multiple functions of bacteriostasis, inflammation diminishing, allergy resistance, prevention of histamine release in vivo and the like, can neutralize or reduce toxic substances of cosmetics, effectively prevents and treats sensitive inflammation and allergy phenomena when skin is stimulated, and has the effects of diminishing inflammation and calming on inflammation caused by sunshine;
the EDTA disodium can generate a stable complex with high-valence metal ions, is soluble in water, replaces the high-valence metal ions with low-valence cations, and prevents insoluble substances from being separated out, cosmetics from discoloring, rancidity, microorganism from growing and the like;
the methyl hydroxybenzoate broad-spectrum antibacterial agent has strong inhibition capacity on mould, and ensures the product quality to be safe and effective;
the active structure of beta-glucan is polysaccharide composed of glucose units, and it can activate macrophage, neutrophilic leukocyte, etc., thus increasing the content of leukocytin, cytokinin and special antibody, and fully stimulate the immune system of organism. In addition, beta-glucan has the effects of removing free radicals, resisting radiation, preventing infection caused by fungi, bacteria and the like, and is widely used in the cosmetic industry, and in recent years, researches show that the beta-1, 3-glucan can be used as a genetic material playing a core role in life activities, can control cell division and differentiation, regulate cell growth, and has unique biological activity in the aspect of anti-aging, so that the beta-1, 3-glucan is widely used in the beauty and skin care industry in countries in the world at present, particularly in Japan, America, Russia and other countries;
the panthenol is easily absorbed by the skin, has a regulating effect on endogenous biosynthesis of ceramide in the cortex, has an anti-inflammatory effect by being used for nursing the skin, is represented by a deeply penetrating humectant, stimulates the growth of epithelial cells, promotes wound healing, and has an advantage in the effect of brightening the skin color by coordinating with the aloe active substance and maintaining the skin renewal force and the glossiness by compounding the phase A raw material;
the aloe is rich in various vitamins, the vitamins comprise vitamin B1, vitamin B2, vitamin C, vitamin E and nicotinamide, and also comprise polysaccharide compounds and essential amino acids, and show various biological activities, the active matters contained in the aloe have the effects of promoting the growth of fibrin, inhibiting elastase, promoting the synthesis of collagen and removing hydroxyl free radicals, so that the aloe has obvious skin activating and anti-aging effects, and the aloe active matters can play a role in preventing sun, diminishing inflammation, resisting oxidation, matching with the activity of beta-glucan on epidermal cells, have better synergistic effect and more remarkable effect;
the aminomethyl propanol is a mild and safe pH regulator, has high safety factor and no pox-causing property;
phenoxyethanol is colorless transparent oily liquid, can be mixed with water and polar organic solvents such as ethanol, propanol, propylene glycol and the like, can be used for dissolving various components and active ingredients, does not stimulate the skin, does not induce substances of organism mutation in-vitro research, has broad-spectrum antibacterial activity, and has stronger killing effect on pseudomonas aeruginosa;
the essence is used for removing unpleasant odor in the original product;
PEG-35 Castor oil helps to dissolve the essence.
2. The preparation method of the aloe active substance provided by the invention can effectively reduce the damage to the active ingredients, furthest ensure the quality of the aloe active substance, is prepared at normal temperature, is simple and easy to operate, reduces the cost and reduces the loss.
Detailed Description
The invention is further illustrated by the following examples.
Example 1: a skin care product containing aloe active comprises phase A, phase B and phase C;
the phase A consists of the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
the phase C comprises the following raw materials in percentage by mass:
0.05% of C-phase essence
PEG-35 Castor oil 0.3%
Wherein, the aloe active matter in the phase B consists of the following raw materials in percentage by mass:
the preparation method of the aloe skin care product comprises the following steps:
(1) sequentially adding the phase A raw materials into a main pot, starting stirring, uniformly dispersing until no insoluble substances exist, starting heating, heating to 80-85 ℃, preserving heat for 20min, and starting cooling;
(2) preparing aloe active substance, cooling to 45 deg.C, sequentially adding phase B raw materials, and stirring until no insoluble substance exists;
(3) premixing the phase C raw materials, stirring to be uniform and transparent, then slowly adding the mixture into a main pot, stirring to be uniform, cooling to 38 ℃, using filter cloth with more than 400 meshes, filtering and discharging.
The preparation method of the aloe active substance comprises the following steps:
(1) weighing the raw materials according to the mass percent, putting propylene glycol into a first beaker, adding PE9010, and uniformly stirring to obtain a solution 1;
(2) adding Aloe vera extract into solution 1, slowly stirring with glass rod to completely disperse and dissolve Aloe vera extract to obtain solution 2;
(3) adding Aloe Barbadensis Miller leaf water into solution 2, slowly stirring with glass rod, and filtering to obtain Aloe active substance.
Example 2: a skin care product containing aloe active comprises phase A, phase B and phase C;
the phase A consists of the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
2% of phase B aloe active matter
The phase C comprises the following raw materials in percentage by mass:
0.05% of C-phase essence
PEG-35 Castor oil 0.3%
Wherein, the aloe active matter in the phase B consists of the following raw materials in percentage by mass:
the preparation method of the aloe skin care product and the preparation method of the aloe active substance are respectively the same as the example 1.
Example 3: a skin care product containing aloe active comprises phase A and phase B;
the phase A consists of the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
wherein, the aloe active matter in the phase B consists of the following raw materials in percentage by mass:
the preparation method of the aloe skin care product does not add phase C, the other steps are the same as example 1, and the preparation method of the aloe active substance is the same as example 1.
Example 4: a skin care product comprises phase A, phase B and phase C;
the phase A consists of the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
the phase C comprises the following raw materials in percentage by mass:
0.05% of C-phase essence
PEG-35 Castor oil 0.3%
The preparation method of the skin care product does not prepare the aloe active substance any more, and other steps are the same as the example 1.
Example 5: a skin care product containing Aloe active substance with skin whitening, antiaging, and moisturizing effects comprises phase A, phase B, and phase C; the phase A consists of the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
the phase C comprises the following raw materials in percentage by mass:
0.05% of C-phase essence
PEG-35 Castor oil 0.3%
Wherein, the aloe active matter in the phase B consists of the following raw materials in percentage by mass:
the preparation method of the whitening, anti-aging and moisturizing skin care product containing the aloe active substances is respectively the same as that in example 1.
Effect experiment:
study subjects: 50 healthy women of 25-30 years old were divided into five groups of 10 persons/group on a parallel, randomized basis.
A first group of subjects used daily a skin care product containing aloe actives prepared according to example 1;
the second group of subjects used daily a skin care product containing aloe actives prepared according to example 2;
a third group of subjects used daily a skin care product containing aloe actives prepared according to example 3;
a fourth group of subjects used daily the skin care product prepared according to example 4;
the fifth group of subjects used the whitening, anti-aging, moisturizing skin care product containing aloe actives prepared according to example 5 daily;
the corresponding skin care products are used by the testee once in the morning and at night every day, and are not used with other skin care products during the test period.
The experimental results are as follows:
1: experimental results of moisturizing efficacy
(1) Average moisture content test of skin
TABLE 1 average moisture content/% of skin at the same site in the fourth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 28.50 | 29.00 | 30.00 | 28.35 | 28.00 | 25.90 | 26.80 | 27.40 | 26.80 | 26.50 |
| Example 2 | 24.10 | 24.80 | 22.50 | 23.00 | 24.10 | 23.60 | 24.10 | 22.30 | 23.50 | 22.30 |
| Example 3 | 38.90 | 37.30 | 39.60 | 41.50 | 42.30 | 45.70 | 46.90 | 45.10 | 46.50 | 46.40 |
| Example 4 | 24.40 | 25.80 | 24.60 | 23.00 | 23.90 | 24.00 | 23.80 | 22.10 | 24.70 | 25.60 |
| Example 5 | 39.20 | 38.10 | 38.60 | 40.10 | 42.60 | 45.80 | 47.30 | 46.00 | 46.80 | 47.90 |
TABLE 2 average moisture content/% of skin at the same site in the eighth week
It can be seen from table 1 and table 2 that the average moisture content of the skin at the same part is changed, after the skin care products prepared according to the embodiments 3 and 5 are used, the average moisture content of the skin of the volunteers is obviously improved, but the skin care products prepared according to the embodiment 3 have 8 volunteers which show poor use feeling and relatively unpleasant smell, and compared with the skin care product prepared according to the embodiment 5, the skin care product prepared according to the invention has poor integral application effect; the skin care product prepared according to example 4 had poor moisturizing effect due to the absence of aloe actives.
2: experimental results of whitening efficacy
(1) Skin melanin content MI value test:
table 1: MI value of melanin content of the same part in the fourth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 166.45 | 172.65 | 165.54 | 161.23 | 169.45 | 169.62 | 170.00 | 162.89 | 166.71 | 168.91 |
| Example 2 | 167.31 | 169.58 | 170.93 | 159.46 | 162.00 | 170.21 | 168.68 | 169.57 | 164.36 | 163.97 |
| Example 3 | 158.95 | 162.71 | 169.82 | 159.47 | 166.45 | 170.11 | 165.46 | 159.48 | 163.51 | 160.00 |
| Example 4 | 162.41 | 164.75 | 153.61 | 169.42 | 170.10 | 165.32 | 158.43 | 160.56 | 163.75 | 152.00 |
| Example 5 | 169.41 | 158.80 | 166.65 | 170.23 | 156.71 | 162.30 | 166.53 | 165.27 | 159.87 | 164.01 |
Table 2: MI value of melanin content of the same part in the eighth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 140.24 | 144.32 | 141.76 | 143.42 | 141.85 | 145.31 | 142.73 | 139.31 | 140.34 | 141.51 |
| Example 2 | 141.46 | 148.91 | 149.85 | 137.41 | 142.73 | 148.89 | 140.58 | 140.83 | 139.22 | 138.96 |
| Example 3 | 130.01 | 133.73 | 141.52 | 130.34 | 140.31 | 141.30 | 137.43 | 130.51 | 134.62 | 135.54 |
| Example 4 | 139.69 | 142.56 | 140.89 | 140.31 | 141.43 | 138.17 | 139.26 | 140.35 | 138.00 | 139.34 |
| Example 5 | 137.63 | 138.12 | 120.63 | 130.67 | 139.10 | 131.66 | 127.91 | 129.87 | 130.21 | 120.73 |
Note: the MI value of the skin melanin content is indicative of the melanin index, and the larger the MI value, the higher the skin melanin content.
From tables 1 and 2, it can be seen that the skin melanin content of the skin of the subject is obviously reduced gradually after the skin care product containing the aloe active prepared according to the invention, namely the aloe active prepared according to the example 5, and the skin care product provided by the invention shows better whitening effect.
(2) Skin lightness L*Value testing:
table 3: skin brightness L of the same part in the fourth circumference*Value of
Table 4: skin brightness L of the same part in the eighth week*Value of
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 62.31 | 61,64 | 64,26 | 66,71 | 65,23 | 63,72 | 67.23 | 65,41 | 64.31 | 63.22 |
| Example 2 | 65.83 | 68.73 | 64.23 | 65.79 | 66.81 | 64.00 | 65.21 | 65.50 | 63.55 | 62.00 |
| Example 3 | 64.35 | 65.78 | 67.31 | 65.43 | 65.00 | 67.01 | 67.42 | 68.12 | 68.90 | 66.13 |
| Example 4 | 61.67 | 65.19 | 63.35 | 66.78 | 67.31 | 62.00 | 61.76 | 63.64 | 61.14 | 62.98 |
| Example 5 | 64.26 | 64.01 | 65.61 | 63.21 | 63.12 | 64.51 | 66.71 | 66.64 | 66..21 | 65.32 |
Note: skin lightness L*The value characterizes the skin brightness, the change of which represents the change of the skin's degree of blackness, the larger the value, the more the color shifts to white.
From tables 3 and 4, it can be seen that the skin color of the subjects is stable and continuously whitened after the skin care product containing the aloe active provided by the invention is used, and the skin brightness L of the skin care product prepared according to example 4 is tested during the test period*The values slightly fluctuate, indirectly indicating the whitening effect of the aloe actives on the skin.
(3) Skin ITA ° value test
Table 5: skin ITA degree of the same part in the fourth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 44.10 | 48.63 | 39.43 | 41.24 | 43.65 | 42.56 | 45.71 | 42.34 | 41.26 | 49.65 |
| Example 2 | 43.87 | 44.04 | 45.19 | 38.57 | 39.35 | 40.56 | 41.65 | 46.72 | 43.60 | 47.00 |
| Example 3 | 44.71 | 50.32 | 38.97 | 40.26 | 45.64 | 43.78 | 46.24 | 45.67 | 41.98 | 44.01 |
| Example 4 | 43.98 | 44.10 | 42.34 | 43.45 | 40.78 | 45.71 | 46.43 | 41.67 | 49.65 | 42.70 |
| Example 5 | 39.89 | 41.45 | 42.61 | 44.76 | 45.00 | 43.53 | 49.67 | 47.32 | 45.43 | 40.44 |
Table 6: ITA degree of skin at the same part in eighth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 49.32 | 51.63 | 46.53 | 47.35 | 49.62 | 49.23 | 49.82 | 48.55 | 47.87 | 50.32 |
| Example 2 | 49.97 | 48.23 | 46,45 | 45.78 | 41.89 | 45.43 | 46.53 | 46.31 | 47.89 | 49.54 |
| Example 3 | 50.98 | 56.21 | 44.67 | 47.32 | 52,45 | 49.78 | 52.65 | 51.73 | 47.05 | 50.66 |
| Example 4 | 48.23 | 47.12 | 44.34 | 46.23 | 42.40 | 43.45 | 47.34 | 44.65 | 50.42 | 43.67 |
| Example 5 | 49.56 | 50.85 | 49.32 | 51.06 | 52.73 | 49.88 | 56.90 | 54.36 | 52.34 | 48.55 |
Note: a is*Represents the degree of reddish green, + a*Represents red, -a*Represents green; b*Represents the degree of blue-yellow, + b*Represents yellow, -b*Represents blue; the ITA ° value (individual type angle) characterizes the skin brightness, and is calculated by the following formula, wherein the larger the ITA ° value is, the brighter the skin is, and conversely, the darker the skin is.
ITA°＝[Arctan(L*-50/b*)]×180/π
From table 5, table 6, it can be seen that the skin color was better lightened by the subjects using the skin care product containing aloe actives according to the present invention, i.e., prepared according to example 5.
3: experimental results of anti-aging efficacy
(1) By epidermal water loss test
Table 1: the same site in the periphery was determined by the transepidermal water loss rate/%)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | -5.13 | -2.61 | -1.42 | -3.54 | -2.36 | -6.12 | -4.10 | -3.41 | -5.32 | -4.55 |
| Example 2 | -6.56 | -7.43 | -4.35 | -5.67 | -3.54 | -7.41 | -4.23 | -6.74 | -2.63 | -3.65 |
| Example 3 | -5.43 | -6.25 | -6.53 | -5.45 | -4.71 | -7.34 | -6.21 | -3.67 | -5.00 | -4.73 |
| Example 4 | -6.35 | -7.81 | -4.67 | -5.43 | -3.67 | -5.89 | -6.41 | -4.56 | -3.89 | -7.51 |
| Example 5 | -9.21 | -4.65 | -8.71 | -4.32 | -5.78 | -8.00 | -5.71 | -4.53 | -6.43 | -7.34 |
Table 2: (ii) the rate of transepidermal water loss of the same site at week eight/%)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | -15.32 | -12.35 | -11.56 | -14.21 | -12.56 | -16.73 | -14.78 | -113.67 | -15.54 | -15.22 |
| Example 2 | -16.44 | -17.52 | -14.31 | -15.63 | -13.45 | -17.53 | -14.66 | -16.65 | -13.11 | -13.88 |
| Example 3 | -16.53 | -17.57 | -17.69 | -16.98 | -16.56 | -18.34 | -17.45 | -14.51 | -16.56 | -15.32 |
| Example 4 | -16.41 | -17.64 | -15.31 | -14.89 | -14.00 | -16.53 | -16.71 | -15.21 | -14.45 | -16.90 |
| Example 5 | -20.35 | -16.78 | -19.86 | -17.45 | -17.65 | -19.23 | -18.32 | -16.34 | -19.25 | -19.87 |
Note: the skin water dispersion loss reflects the change rule of skin moisture loss along with time in the test period, and the smaller the value, the less the moisture loss, and the better the barrier function of the skin. The water loss rate through the epidermis is calculated by the following formula.
As can be seen from tables 1 and 2, the skin care products containing aloe actives prepared according to example 5 have significantly reduced water loss rate through epidermis after the skin care products are used by the subjects, which indicates that the skin care products provided by the present invention can effectively improve the skin barrier function, thereby better exerting the anti-aging effect.
(2) Skin elasticity test
Table 3: elasticity of skin at the same position around the fourth
Table 4: the skin elasticity change of the same part in the eighth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 0.66 | 0.67 | 0.71 | 0.62 | 0.62 | 0.61 | 0.59 | 0.69 | 0.60 | 0.63 |
| Example 2 | 0.73 | 0.70 | 0.71 | 0.66 | 0.66 | 0.67 | 0.55 | 0.61 | 0.63 | 0.61 |
| Example 3 | 0.70 | 0.69 | 0.72 | 0.71 | 0.86 | 0.79 | 0.75 | 0.63 | 0.71 | 0.62 |
| Example 4 | 0.64 | 0.65 | 0.63 | 0.55 | 0.50 | 0.53 | 0.66 | 0.55 | 0.57 | 0.62 |
| Example 5 | 0.80 | 0.71 | 0.80 | 0.78 | 0.89 | 0.79 | 0.81 | 0.82 | 0.76 | 0.93 |
Note: the ratio of the amount of springback of the skin in the absence of negative pressure to the maximum amount of stretching in the presence of negative pressure, and the closer the value is to 1, the better the skin elasticity is.
As can be seen from tables 3 and 4, the skin elasticity of the skin was enhanced and the skin was firmed after the skin care product containing aloe actives according to the present invention, i.e., prepared according to example 5, was used by the subjects.
(3) Skin wrinkle testing
Table 5: the skin wrinkles at the same part in the fourth week
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Example 1 | 40.70 | 39.21 | 41.53 | 40.21 | 39.65 | 43.05 | 42.61 | 41.55 | 42.37 | 39.68 |
| Example 2 | 39.34 | 40.03 | 42.32 | 41.21 | 38.67 | 40.23 | 39.65 | 42.55 | 37.71 | 38.62 |
| Example 3 | 44.20 | 43.24 | 39.67 | 41.25 | 38.69 | 40.02 | 42.45 | 40.66 | 38.73 | 41.65 |
| Example 4 | 38.22 | 39.71 | 40.08 | 43.25 | 42.43 | 41.72 | 39.61 | 41.55 | 38.78 | 40.86 |
| Example 5 | 42.34 | 40.56 | 39.47 | 39.21 | 37.44 | 39.63 | 40.19 | 42.45 | 38.77 | 41.45 |
Table 6: the same part of skin wrinkles in the eighth week
Note: the smaller the number, the smaller the number of wrinkles.
As can be seen from tables 5 and 6, the skin care product containing aloe actives provided by the present invention has the effect of significantly improving fine lines.
According to the experimental results of the moisturizing effect, the whitening effect and the anti-aging effect, the aloe active substance has obvious brightening and anti-aging effects, and has the advantages of brightening the skin color and resisting aging effects by cooperating with the activity of beta-glucan in the B phase on epidermal cells; the components in the skin care product containing the aloe active matter provided by the invention fully play roles in the formula and have a synergistic effect with each other, so that the formula effect is more reasonable and effective, the whole skin care product has excellent effects of brightening, moisturizing and resisting aging, the product quality is safe and effective, and meanwhile, the skin care product has a good use experience effect.
Claims (5)
1. A whitening, anti-aging and moisturizing skin care product containing aloe active substances is characterized in that: comprises a phase A, a phase B and a phase C;
the phase A comprises the following raw materials in percentage by mass:
the phase B comprises the following raw materials in percentage by mass:
the phase C comprises the following raw materials in percentage by mass:
0.05% of C-phase essence
PEG-35 castor oil 0.3%.
2. The whitening, anti-aging and moisturizing skin care product containing aloe active substances according to claim 1, wherein the aloe active substances in the phase B consist of the following raw materials in percentage by mass:
3. the whitening, anti-aging and moisturizing skin care product containing aloe active substances according to claim 2, wherein the aloe active substances in the phase B consist of the following raw materials in percentage by mass:
4. the method for preparing the aloe-active-containing whitening, anti-aging and moisturizing skin care product according to any one of claims 1 to 3, characterized by comprising the following steps:
(1) sequentially adding the phase A raw materials into a main pot, starting stirring, uniformly dispersing until no insoluble substances exist, starting heating, heating to 80-85 ℃, preserving heat for 20min, and starting cooling;
(2) preparing aloe active substances in advance, cooling the main pot to 45 ℃, sequentially adding the phase B raw materials, and stirring until no insoluble substances exist;
(3) premixing the phase C raw materials, stirring to be uniform and transparent, then slowly adding the mixture into a main pot, stirring to be uniform, cooling to 38 ℃, using filter cloth with more than 400 meshes, filtering and discharging.
5. The preparation method of the aloe-active-containing whitening, anti-aging and moisturizing skin care product as claimed in claim 4, wherein the preparation method of the aloe-active is as follows:
(1) weighing the raw materials according to the mass percent, putting propylene glycol into a first beaker, adding PE9010, and uniformly stirring to obtain a solution 1;
(2) adding Aloe vera extract into solution 1, slowly stirring with glass rod to completely disperse and dissolve Aloe vera extract to obtain solution 2;
(3) adding Aloe Barbadensis Miller leaf water into solution 2, slowly stirring with glass rod, and filtering to obtain Aloe active substance.
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| CN114159371A (en) * | 2022-01-09 | 2022-03-11 | 广东荟宝化妆品有限公司 | Composition containing Aloe arborescens Miller and application thereof |
| CN114224762A (en) * | 2021-12-30 | 2022-03-25 | 广东荟宝化妆品有限公司 | Composition containing aloesin and preparation method and application thereof |
| CN114272190A (en) * | 2022-01-19 | 2022-04-05 | 郑州凯莉莱生物科技有限公司 | Composition containing aloe active compound and preparation method and application thereof |
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| CN114224762A (en) * | 2021-12-30 | 2022-03-25 | 广东荟宝化妆品有限公司 | Composition containing aloesin and preparation method and application thereof |
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