CN114159371A - Composition containing Aloe arborescens Miller and application thereof - Google Patents

Composition containing Aloe arborescens Miller and application thereof Download PDF

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Publication number
CN114159371A
CN114159371A CN202210018856.6A CN202210018856A CN114159371A CN 114159371 A CN114159371 A CN 114159371A CN 202210018856 A CN202210018856 A CN 202210018856A CN 114159371 A CN114159371 A CN 114159371A
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phase
extract
skin
composition
aloe
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王永健
马春雨
孟阿芳
郭永民
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Zhengzhou Kelly Lai Biotechnology Co ltd
Guangdong Huibao Cosmetics Co ltd
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Zhengzhou Kelly Lai Biotechnology Co ltd
Guangdong Huibao Cosmetics Co ltd
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Priority to CN202210018856.6A priority Critical patent/CN114159371A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/37Esters of carboxylic acids
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    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
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    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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    • A61K2800/49Solubiliser, Solubilising system
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    • A61K2800/524Preservatives
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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Abstract

The invention discloses a composition containing aloe arborescens and application thereof, belonging to the technical field of cosmetics; the composition comprises deionized water, a thickener and humectant of phase A, an active of phase C, a flavoring agent and a solubilizer of phase D; the active matter of the phase C comprises 0.1-10% of the compound active extract of the aloe arborescens extract and the compound plant extract, and the compound plant extract is prepared by compounding one or more of 0.05-3% of the purple snow ginseng nourishing oil, 0.05-3% of the beneficial oil, 0.05-3% of the Yuyan Xinyan and 0.05-3% of the peach red four-substance distillate; the composition containing Aloe arborescens can be used in skin care products. According to the aloe arborescens extract-compounded composite plant extract composition, the active substances are formed, so that the plant extracts can play a synergistic effect in the whole formula system, and the effects of whitening and brightening skin are obviously enhanced; the skin whitening and whitening cream can reduce the melanin content of the skin, improve the elasticity of the skin, reduce the heme content and improve the skin color.

Description

Composition containing Aloe arborescens Miller and application thereof
Technical Field
The invention relates to a whitening skin care product containing aloe extract, in particular to a composition containing arborescent aloe and application thereof, belonging to the technical field of cosmetics.
Background
The existing whitening products mostly adopt aloe extracts and nicotinamide to achieve the whitening effect, for example, the invention patent with application publication number of CN111012713A, namely 'whitening composition and preparation method and application thereof', the patent is just the combination of aloesin and nicotinamide, and the skin whitening is comprehensively considered in all links from melanin generation to melanin entering stratum corneum prevention and the like, so that the balanced whitening effect can be achieved. However, compared with the commercially available whitening essence, the skin melanin content MI value and the skin brightness L value in the whitening effect test of the patent are not obvious in effect test difference, and the maximum reduction value of the skin melanin content MI value is only 29.06.
Modern science proves that hundreds of chemical components are contained in the arborescent aloe, wherein the applied chemical components are over 100, and the arborescent aloe is widely applied to the fields of beauty treatment, health care, medical treatment and the like. Aloe arborescens leaf is filled with a gel beneficial for skin care, contains many valuable nutrients including vitamins, minerals, enzymes, oil (fat), amino acids and mucopolysaccharide with therapeutic effect, and has effects of effectively improving rough skin, removing black speck, freckle, etc.
The aim of whitening is achieved by adding the aloe arborescens into the existing whitening products generally by inhibiting the synthesis of melanin, but the whitening effect is not obvious, and the existing whitening products are often accompanied with skin states such as poor skin elasticity, reddish skin and the like. Therefore, a whitening formula which can cooperate with the arborescent aloe is urgently needed, and the whitening formula has the function of improving the skin condition while achieving the whitening effect obviously.
Disclosure of Invention
The purpose of the invention is: the aloe arborescens extract is compounded with the composite plant extract to form the active substance which is applied to the skin care product, so that the plant extracts can play a synergistic effect in the whole formula system, and the effects of whitening and brightening the skin color are obviously enhanced; the skin whitening and whitening cream can reduce the melanin content of the skin, improve the elasticity of the skin, reduce the heme content and improve the skin color.
In order to achieve the purpose, the invention adopts the following technical scheme: a composition comprising Aloe arborescens, said composition comprising deionized water, a thickener and humectant in phase A, an active in phase C, a fragrance and solubilizer in phase D;
the active matter of the phase C comprises 0.1-10% of the compound active extract of the aloe arborescens extract and the compound plant extract, and the compound plant extract is prepared by compounding one or more of 0.05-3% of the purple snow ginseng nourishing oil, 0.05-3% of the beneficial oil, 0.05-3% of the Yuyan Xinyan and 0.05-3% of the peach red four-substance distillate;
the red-snowbell nourishing oil is prepared by compounding caprylic/capric triglyceride, hydrogenated polyisobutene, a red-glossy ganoderma extract, a snow lotus extract, a ginseng root extract and a peony extract;
the beneficial oil is prepared by compounding caprylic/capric triglyceride, sunflower seed extract, peony extract, grape seed extract, perilla seed extract, isostearyl isostearate, tocopheryl acetate, ascorbyl tetraisopalmitate and retinol palmitate;
the Yuyangxin Yan is prepared by compounding water, butanediol, a angelica root extract, a pseudo-ginseng root extract, an astragalus membranaceus root extract, a glossy privet seed extract and a licorice root extract;
the four-component peach blossom distillate is prepared by compounding water, butanediol, peach blossom extract, peony blossom extract, safflower blossom extract and peony branch/flower/leaf extract.
The composition also comprises a preservative and a phase A pH regulator, wherein the phase A comprises 0.1-2% of a thickening agent, 1-10% of a humectant and 0.1-2% of a pH regulator in percentage by mass, the phase C comprises 0.1-10% of an aloe arborescens extract and 0.05-12% of a compound plant extract, the phase D comprises 0.01-0.1% of a flavoring agent and 0.05-0.5% of a solubilizer, the preservative is 1-2%, and the balance of deionized water is the balance of the composition.
The composition is applied to skin care product aqua, the thickener of the phase A is one or more of carbomer, xanthan gum, hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer and triethanolamine, the humectant is one or more of glycerin and propylene glycol, and the pH regulator is triethanolamine; the preservative is an HTsoft-5688 substitute type preservative; the active matter of the phase C comprises one or two of Yuyan Xinyan and Taohong four distillate in the compound plant extract compounded by the purslane extract and the aloe arborescens extract; the fragrance of phase D is selected from PSP-HB210449A Aloe Vera, and the solubilizer is selected from SIMPSOL TM SP-115A or Eumulgin HPS.
The preparation method of the composition containing the arborescent aloe applied to the skin care product aqua comprises the following steps:
s1, weighing deionized water according to the mass percent of the composition, pouring the deionized water into a dry and clean beaker, adding the phase A raw material into an emulsifying pot, stirring and homogenizing, uniformly dispersing until no insoluble substances exist, heating to 80-85 ℃, preserving heat for 20min, and beginning to cool;
s2, cooling the emulsifying pot to 45 ℃, sequentially adding the phase C raw material and the preservative, and stirring until the mixture is uniform and no insoluble substances exist;
s3, premixing the phase D raw materials, stirring uniformly and transparently, slowly adding into an emulsifying pot, stirring uniformly, cooling to 38 ℃, after passing the inspection, using filter cloth with more than 400 meshes, filtering and discharging to obtain the skin care product aqua containing the arborescent aloe.
The composition is applied to the skin care product emulsion cream after the emulsifier and the grease of the phase B are added into the composition, the emulsifier of the phase B in the composition accounts for 3-8% by mass of the composition, the grease comprises one or two of 0.05-3% of purple snow ginseng nourishing oil and 0.05-3% of health preserving oil, and the balance of the composition is deionized water.
The thickening agent of the phase A is one or more of carbomer, xanthan gum, hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer and triethanolamine, the humectant is one or more of glycerol and propylene glycol, and the pH regulator is triethanolamine; the preservative is an HTsoft-5688 substitute type preservative; the emulsifier of the phase B is one or more of cetyl alcohol, glyceryl stearate, PEG-75 stearate, ceteth-20 and steareth-20; the active matter of the C phase comprises one or two of an aloe arborescens extract and a purslane extract; the fragrance of phase D is selected from PSP-HB210449A Aloe Vera, and the solubilizer is selected from SIMPSOL TM SP-115A or Eumulgin HPS.
A preparation method of a composition containing aloe arborescens applied to a skin care product emulsion cream comprises the following steps:
s1, weighing deionized water according to the mass percent of the composition, pouring the deionized water into a dry and clean beaker, adding the phase A raw material into an emulsifying pot, stirring and homogenizing, uniformly dispersing until no insoluble substances exist, heating to 80-85 ℃, and keeping the temperature for 20 min;
s2, keeping the temperature at 80 ℃, adding the phase B raw material, slightly homogenizing until complete emulsification, stirring and keeping the temperature for 30 min;
s3, cooling the emulsifying pot to 45 ℃, sequentially adding the phase C raw material and the preservative, and stirring until the mixture is uniform and no insoluble substances exist;
s4, premixing the phase D raw materials, stirring uniformly and transparently, slowly adding into an emulsifying pot, stirring uniformly, cooling to 38 ℃, after the inspection is qualified, using filter cloth with more than 400 meshes, filtering and discharging to obtain the skincare product emulsion cream containing the aloe arborescens.
The composition is applied to skin care product gel, the thickening agent of the phase A is one or more of sclerotium rolfsii gum, carbomer, xanthan gum, hydroxyethyl acrylate/acryloyl dimethyl taurate copolymer and triethanolamine, the humectant is one or more of glycerin and propylene glycol, and the pH regulator is triethanolamine; the preservative is an HTsoft-5688 substitute type preservative; the active matter of the phase C comprises one or more of a compound plant extract of purslane extract and aloe arborescens extract; the fragrance of phase D is selected from PSP-HB210449A Aloe Vera, and the solubilizer is selected from SIMPSOL TM SP-115A or Eumulgin HPS.
The preparation method of the composition containing the arborescent aloe applied to the skin care jelly comprises the following steps:
s1, weighing deionized water according to the mass percent of the composition, pouring the deionized water into a dry and clean beaker, adding the phase A raw material into an emulsifying pot, stirring and homogenizing, uniformly dispersing until no insoluble substances exist, heating to 80-85 ℃, preserving heat for 20min, and beginning to cool;
s2, cooling the emulsifying pot to 45 ℃, sequentially adding the phase C raw material and the preservative, and stirring until the mixture is uniform and no insoluble substances exist;
s3, premixing the phase D raw materials, stirring uniformly and transparently, slowly adding into an emulsifying pot, stirring uniformly, cooling to 38 ℃, after the inspection is qualified, using filter cloth with more than 400 meshes, filtering and discharging to obtain the skin care product gel containing the aloe arborescens.
The invention has the beneficial effects that:
1) according to the aloe arborescens extract and the preparation method thereof, the aloe arborescens extract is compounded with the composite plant extract to form the active substance which is applied to the skin care product, so that the plant extracts can play a synergistic effect in the whole formula system, and the effects of whitening and brightening the skin color are obviously enhanced; the aloe arborescens extract and the compound plant extract are both derived from natural plant extracts, are safe and effective, and can be widely applied to skin care varieties such as water aqua, emulsion cream, jelly and the like of general cosmetics in a reasonable adding range.
2) The compound plant extract in the active matter of the invention achieves the effects of inhibiting the generation of melanin, improving the activity of skin and resisting aging by compounding and cooperating one or more extracts of the four-extract lotion of red-snow ginseng, wild oil, Yuyan Xinyan and peach red.
The radix salviae miltiorrhizae nourishing oil mainly nourishes blood and activates blood, and nourishes, so that qi and blood in the skin are sufficient, and the skin is nourished properly and treated with both symptoms and root causes, thereby effectively fading fine wrinkles of the skin, increasing the elasticity of the skin, improving the roughness of the skin and improving the brightness and glossiness of the skin while repairing the barrier of the skin.
The health-care oil is based on the supplementation of skin lipid, vitamins and minerals, and four plant essences of peony seeds, perilla seeds, grape seeds and sunflower seeds balance the nutrition of skin, thereby achieving the effects of lubricating the skin, promoting the metabolism and restoration of the skin and improving the skin state.
The Yuyan Xinyan is based on the qi-blood theory of traditional Chinese medicine and is combined with plant formula functional raw materials developed by modern skin science, and the five herbal medicines meet and cooperate with each other to ensure that the skin has sufficient qi and blood, consolidate the inherent nutrient channel of the skin, recover the elasticity of the skin, improve the brightness of the skin, effectively improve the darkness, increase the firmness of the skin, make the skin young and active, and make the skin healthy and good in complexion.
The peach blossom and safflower four-component dew integrates essence of peach blossom, safflower, peony flower and peony flower, is rich in nutrient components such as flavonoid, vitamin C, amino acid, polyphenol, saccharides and the like, and has excellent effects of scavenging free radicals and delaying senescence.
3) The aloe arborescens extract in the active matter is rich in various nutrients, shows various biological activities, has a promoting effect on growth of fibrin, an inhibiting effect on elastase, a promoting effect on synthesis of collagen, a removing effect on hydroxyl free radicals, and has obvious skin-activating and anti-aging effects; by promoting the synthesis of cholesterol, the skin care product is beneficial to changing the composition of skin sebum, reducing the gloss of oil and increasing the softness of the skin; aloin exerts a whitening effect by inhibiting tyrosinase, a key enzyme in melanogenesis.
4) The active matter of the invention also adjusts the skin state by adding the purslane extract, wherein the purslane extract has the functions of relieving, diminishing inflammation and resisting oxidation; the purslane extract is rich in a large amount of flavonoids, adrenalines, polysaccharides, various vitamins, amino acids and other compounds, the plant polysaccharides and the vitamins can nourish and lubricate the skin and promote the physiological function of epithelial cells to be normal, dead skin and cuticle generation caused by dryness can be reduced, the amino acids can shrink vascular smooth muscles, the central nervous system and peripheral nerve with the function of shrinking can be shrunk, the skin can be relieved, skin itching caused by dryness can be inhibited, and the flavones and the saponins can remove free radicals, resist oxidation and delay skin aging. The alkaloids and flavones can be used for resisting bacteria and inhibiting common pathogenic dermatophytes.
5) The propylene glycol in the formula has a moisturizing function, can help active ingredients of the skin to permeate into the skin, has an antiseptic effect, belongs to a small molecular moisturizing ingredient, and can retain water in the horny layer.
The glycerin molecule can form hydrogen bond with water molecule to make glycerin have water absorption, so as to form a film on skin, which has effects of isolating air and preventing water evaporation, and can absorb water in air to make skin keep soft and elastic, and is not damaged by dust, climate, etc. and dry, and has effects of keeping moisture and preventing skin frostbite.
Carbomer has good transparency and obvious shear thinning characteristic, can provide good suspension capacity, protect skin, reduce irritant substances and prevent various allergic symptoms; has certain looseness, and a proper amount of carbomer can be added when the gel or the cosmetic is prepared, so that the viscosity of the substances is reduced, and the stability of the effective substances is maintained; the quality of the cosmetic can be ensured by some neutralization.
The xanthan gum can play a moisturizing role, and can enable the skin to obtain more moisture, so that the skin looks more delicate and smooth. In addition, the skin care product can balance substances in the skin;
6) in the formula of the invention, HTsoft-5688 is an alternative preservative which consists of dipropylene glycol, isoprene glycol, caprylyl glycol, 1, 2-hexanediol and p-hydroxyacetophenone; has mild and non-irritant application, broad-spectrum antibacterial property and higher efficiency.
The triethanolamine is used as a neutralizer, a humectant and a moisturizer in cosmetics, can play roles of thickening and moisturizing, enables the paste body to be finer and brighter in a cream preparation, increases the experience feeling of a user, and ensures the stability of the product quality.
PEG-35 castor oil in solubilizer SIMPSOL TM SP-115A helps to dissolve essence, and the essence improves product odor and improves overall use feeling.
Drawings
FIG. 1 is a graph showing melanin content in the skin of the same part of different subjects tested in example 1;
FIG. 2 is a graph of ITA DEG for the skin color difference of the same part of different testers based on the test of example 1;
FIG. 3 is a graph of the skin elasticity of the same part of different subjects tested in example 1;
FIG. 4 is a graph of hemoglobin content of the skin of the same area of different subjects tested in example 1;
FIG. 5 is a graph showing melanin contents in the skin at the same site in different experimental groups based on example 1 and a control group;
FIG. 6 is a graph of ITA DEG values of skin color difference at the same site in different experimental groups tested based on example 1 and a control group.
Detailed Description
The invention is further explained below with reference to the figures and the embodiments.
In the following examples, SIMPSOL TM SP-115A was selected from Shanghai Xinpu Biotech Co., Ltd, and the supplier was Guangzhou West Productivity Fine chemical engineering Co., Ltd; PSP-HB210449A Aloe Vera was selected as a product of manufacturer and supplier from Baisheng Natural aroma and flavor factory, litchi bay, Guangzhou city.
Example 1: taking a typical formula of a composition compounded by an aloe arborescens extract and a composite plant extract as an example, a skin care product aqua essence example 1 is prepared by using the typical formula of the composition, and a performance experiment of the skin care product is carried out, wherein the formula table 1 is as follows:
Figure BDA0003461653380000081
Figure BDA0003461653380000091
the melanin contents MI values of the CK test effect obtained by testing the melanin contents of the skin of the same part using different testers using the formula table 1 are shown in table 1 below:
different testers Test site Base value First week Second week The third week The fourth side
Tester 1 Right cheek 171 104 117 89 112
Tester 2 Right cheek 172 109 125 100 105
Tester 3 Right cheek 183 112 126 104 105
Tester 4 Right cheek 175 108 122 97 107
Note: the MI value of the skin melanin content is indicative of the melanin index, and the larger the MI value, the higher the skin melanin content.
As can be seen from the above melanin content MI values table 1 and the accompanying drawing 1, after the skin care product aqua essence compounded by the aloe arborescens extract and the composite plant extract is used, the skin melanin content of all testers is remarkably reduced, and the skin care product aqua essence has great efficacy on reducing the skin melanin content and whitening the skin.
The formula table 1 is used for testing the color difference of the skin at the same part by adopting different testers, and the ITA degree value table 2 of the skin color difference of the CK test effect is as follows:
different testers Test site Base value First week Second week The third week The fourth side
Tester 1 Right cheek 25 29 30 30 32
Tester 2 Right cheek 32 30 32 29 35
Tester 3 Right cheek 27 29 27 29 32
Tester 4 Right cheek 28 29 30 29 33
Note: a represents the red-green shade, + a represents red, -a represents green; b represents the blue yellow degree, + b represents yellow, -b represents blue; the ITA ° value (individual type angle) characterizes skin brightness and is calculated from the following formula:
Figure BDA0003461653380000101
the greater the ITA ° value, the brighter the skin, and conversely, the darker the skin.
As can be seen from the table 2 and the attached figure 2 of the skin color difference ITA ° values, after the skin care product aqua essence compounded by the aloe arborescens extract and the composite plant extract is used, the skin color difference ITA ° values of all testers are obviously increased, and a certain brightening effect is shown on the skin color of all testers.
The formula table 1 is used for testing the elasticity of the skin at the same part by different testers, and the skin elasticity value table 3 for obtaining the CK test effect is as follows:
different testers Test site Base value First week Second week The third week The fourth side
Tester 1 Right cheek 56.5 74.5 67.9 65.4 58.4
Tester 2 Right cheek 61.3 62.1 59.2 66.3 64.3
Tester 3 Right cheek 63 69.4 69.2 69.6 69.7
Tester 4 Right cheek 60.3 68.6 65.4 67.1 64.1
Note: the skin elasticity ratio refers to the percentage of the rebound quantity of the skin without negative pressure to the maximum stretching quantity with negative pressure, and the larger the skin elasticity percentage value is, the better the skin elasticity is.
As can be seen from the skin elasticity value table 3 and the attached figure 3, after the skin care product aqua essence compounded by the aloe arborescens extract and the composite plant extract is used, the skin elasticity value of all testers is obviously increased, and the skin elasticity of all testers is improved.
The skin hemoglobin content values of the CK test effect obtained by testing the hemoglobin content of the skin of the same part by using different testers in the formula table 1 are shown in the table 4 as follows:
different testers Test site Base value First week Second week The third week The fourth side
Tester 1 Right cheek 265 258 202 281 286
Tester 2 Right cheek 267 242 201 245 255
Tester 3 Right cheek 280 271 207 301 310
Tester 4 Right cheek 246 257 203 278 283
Note: human skin tends to be redder when hemoglobin content is higher.
As can be seen from the skin hemoglobin content table 4 and the attached figure 4, after the skin care product essence compounded by the aloe arborescens extract and the composite plant extract is used, the skin hemoglobin content of most of testers is obviously increased, and the display of the tester 2 is reduced, so that the skin complexion of the testers is improved to a certain extent.
By combining the four performance effects of the CK test, the formula of the composition compounded by the aloe arborescens extract and the composite plant extract in the embodiment 1 of the invention has the obvious effects of inhibiting melanin formation, whitening and brightening, and can improve the skin elasticity and the heme content to a certain extent.
The formula table 1 is utilized to respectively adopt three different control groups to carry out control experiments, and the control effect of the formula of the composition compounded by the arborescent aloe extract and the composite plant extract on inhibiting melanin formation and whitening and brightening is verified.
Control group 1: taking a typical formula of the composition only containing the composite plant extract as an example, and preparing a skin care product aqua essence control group 1 by using the typical formula of the composition, the formula table 2 is as follows:
Figure BDA0003461653380000111
Figure BDA0003461653380000121
control group 2: taking a typical formula of the composition only containing the aloe arborescens extract as an example, and preparing a skin care product aqua essence control group 2 by using the typical formula of the composition, a performance test of the skin care product is carried out, and the formula of the skin care product is shown in the following table 3:
Figure BDA0003461653380000122
Figure BDA0003461653380000131
control group 3: taking a typical formula of a composition compounded by nicotinamide and a composite plant extract as an example, and preparing a skin care product aqua essence control group 3 by using the typical formula of the composition, a performance experiment of the skin care product is carried out, and a formula table 4 is as follows:
Figure BDA0003461653380000132
Figure BDA0003461653380000141
the melanin contents MI values of the CK test effect obtained by testing the melanin contents of the skin of the same part using different control groups using the formula table 1 are shown in table 5 below:
different experimental groups Test site Base value First week Second week The third week The fourth side
Control group 1 Right cheek 170 157 136 123 128
Control group 2 Right cheek 167 149 124 112 121
Control group 3 Right cheek 177 115 102 94 105
Example 1 Right cheek 185 121 107 80 97
As can be seen from the above melanin content MI values table 5 and fig. 5, the decrease of the melanin content of the skin of the testees of the control 1 and the control 2 is not significant, and the effect of decreasing the melanin content of the skin of the testees of the control 3 is obviously better than that of the example 1, and the Δ MI value of the decrease of the melanin content of the example 1 is 88, that is, the essence whitening effect of the combination of the aloe arborescens and the composite plant extract is more excellent.
The color difference of the skin at the same position is tested by using different control groups according to the formula table 1, and the ITA DEG value of the skin color difference of CK test effect is obtained as follows:
different experimental groups Test site Base value First week Second week The third week The fourth side
Control group 1 Right cheek 25 27 28 27 29
Control group 2 Right cheek 30 31 33 32 34
Control group 3 Right cheek 29 31 35 33 36
Example 1 Right cheek 32 34 39 38 40
As can be seen from the skin color difference ITA ° value table 6 and the attached drawing 6, the skin lightening effect of the testers of the control 2 and the control 1 is not obvious, the skin lightening effect of the testers of the embodiment 1 is superior to that of the control 3, the Δ ITA ° value of the color difference increase of the embodiment 1 is 8, that is, the skin lightening effect of the essence compounded by the aloe arborescens and the composite plant extract is more obvious.
Combining the above experimental results to obtain: when the active matter consisting of the aloe arborescens extract and the compound plant extract is added into the composition to prepare the skin care product, the plant extracts can play a synergistic effect in the whole formula system, and the effects of whitening and brightening the skin color are obviously enhanced; the compounded active matter is superior to the existing whitening products and the single component in the effects of reducing the melanin content of the skin and whitening and brightening the skin; in addition, the compounded active matter also has the effects of improving the skin elasticity, reducing the heme content and improving the skin color.
The above description is only for the purpose of illustrating the technical solutions of the present invention and not for the purpose of limiting the same, and other modifications or equivalent substitutions made by those skilled in the art to the technical solutions of the present invention should be covered within the scope of the claims of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (6)

1. A composition comprising Aloe arborescens, characterized by: the composition comprises deionized water, a thickener and humectant of phase A, an active of phase C, a flavoring agent and a solubilizer of phase D;
the active matter of the phase C comprises 0.1-10% of the compound active extract of the aloe arborescens extract and the compound plant extract, and the compound plant extract is prepared by compounding one or more of 0.05-3% of the purple snow ginseng nourishing oil, 0.05-3% of the beneficial oil, 0.05-3% of the Yuyan Xinyan and 0.05-3% of the peach red four-substance distillate;
the red-snowbell nourishing oil is prepared by compounding caprylic/capric triglyceride, hydrogenated polyisobutene, a red-glossy ganoderma extract, a snow lotus extract, a ginseng root extract and a peony extract;
the beneficial oil is prepared by compounding caprylic/capric triglyceride, sunflower seed extract, peony extract, grape seed extract, perilla seed extract, isostearyl isostearate, tocopheryl acetate, ascorbyl tetraisopalmitate and retinol palmitate;
the Yuyangxin Yan is prepared by compounding water, butanediol, a angelica root extract, a pseudo-ginseng root extract, an astragalus membranaceus root extract, a glossy privet seed extract and a licorice root extract;
the four-component peach blossom distillate is prepared by compounding water, butanediol, peach blossom extract, peony blossom extract, safflower blossom extract and peony branch/flower/leaf extract.
2. A composition according to claim 1, comprising aloe arborescens in an amount effective to reduce: the composition also comprises a preservative and a phase A pH regulator, wherein the phase A comprises 0.1-2% of a thickening agent, 1-10% of a humectant and 0.1-2% of a pH regulator in percentage by mass, the phase C comprises 0.1-10% of an aloe arborescens extract and 0.05-12% of a compound plant extract, the phase D comprises 0.01-0.1% of a flavoring agent and 0.05-0.5% of a solubilizer, the preservative is 1-2%, and the balance of deionized water is the balance of the composition.
3. Use of a composition according to any of claims 1 to 2 in a skin care lotion, wherein: the thickening agent of the phase A is one or more of carbomer, xanthan gum, hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer and triethanolamine, the humectant is one or more of glycerol and propylene glycol, and the pH regulator is triethanolamine; the preservative is an HTsoft-5688 substitute type preservative; the active matter of the phase C comprises one or two of Yuyan Xinyan and Taohong four distillate in the compound plant extract compounded by the purslane extract and the aloe arborescens extract; the aromatic of phase D is selected from PSP-HB210449A Aloe Vera, and the solubilizer is selected from SIMPSOL TM SP-115A or Eumulgin HPS;
the preparation method of the composition containing the arborescent aloe applied to the skin care product aqua comprises the following steps:
s1, weighing deionized water according to the mass percent of the composition, pouring the deionized water into a dry and clean beaker, adding the phase A raw material into an emulsifying pot, stirring and homogenizing, uniformly dispersing until no insoluble substances exist, heating to 80-85 ℃, preserving heat for 20min, and beginning to cool;
s2, cooling the emulsifying pot to 45 ℃, sequentially adding the phase C raw material and the preservative, and stirring until the mixture is uniform and no insoluble substances exist;
s3, premixing the phase D raw materials, stirring uniformly and transparently, slowly adding into an emulsifying pot, stirring uniformly, cooling to 38 ℃, after passing the inspection, using filter cloth with more than 400 meshes, filtering and discharging to obtain the skin care product aqua containing the arborescent aloe.
4. Use of a composition according to any of claims 1-2 in a skin care emulsion cream wherein: the emulsifier and the grease of the phase B are added into the composition and then applied to the skin care product emulsion cream, the emulsifier of the phase B in the composition accounts for 3-8% by mass of the composition, the grease comprises one or two of 0.05-3% of the red sage root nourishing oil and 0.05-3% of the beneficial oil, and the balance of the composition is deionized water.
5. Use of a composition according to claim 4 in a skin care emulsion cream characterized in that: the thickening agent of the phase A is one or more of carbomer, xanthan gum, hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer and triethanolamine, the humectant is one or more of glycerol and propylene glycol, and the pH regulator is triethanolamine; the preservative is an HTsoft-5688 substitute type preservative; the emulsifier of the phase B is one or more of cetyl alcohol, glyceryl stearate, PEG-75 stearate, ceteth-20 and steareth-20; the active matter of the C phase comprises one or two of an aloe arborescens extract and a purslane extract; the aromatic of phase D is selected from PSP-HB210449A Aloe Vera, and the solubilizer is selected from SIMPSOL TM SP-115A or Eumulgin HPS;
a preparation method of a composition containing aloe arborescens applied to a skin care product emulsion cream comprises the following steps:
s1, weighing deionized water according to the mass percent of the composition, pouring the deionized water into a dry and clean beaker, adding the phase A raw material into an emulsifying pot, stirring and homogenizing, uniformly dispersing until no insoluble substances exist, heating to 80-85 ℃, and keeping the temperature for 20 min;
s2, keeping the temperature at 80 ℃, adding the phase B raw material, slightly homogenizing until complete emulsification, stirring and keeping the temperature for 30 min;
s3, cooling the emulsifying pot to 45 ℃, sequentially adding the phase C raw material and the preservative, and stirring until the mixture is uniform and no insoluble substances exist;
s4, premixing the phase D raw materials, stirring uniformly and transparently, slowly adding into an emulsifying pot, stirring uniformly, cooling to 38 ℃, after the inspection is qualified, using filter cloth with more than 400 meshes, filtering and discharging to obtain the skincare product emulsion cream containing the aloe arborescens.
6. Use of the composition of any of claims 1-2 in a skin care gel wherein: the thickening agent of the phase A is one or more of sclerotium rolfsii gum, carbomer, xanthan gum, hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer and triethanolamine, the humectant is one or more of glycerin and propylene glycol, and the pH regulator is triethanolamine; the preservative is an HTsoft-5688 substitute type preservative; the active matter of the phase C comprises one or more of a compound plant extract of purslane extract and aloe arborescens extract; the aromatic of phase D is selected from PSP-HB210449A Aloe Vera, and the solubilizer is selected from SIMPSOL TM SP-115A or Eumulgin HPS;
the preparation method of the composition containing the arborescent aloe applied to the skin care jelly comprises the following steps:
s1, weighing deionized water according to the mass percent of the composition, pouring the deionized water into a dry and clean beaker, adding the phase A raw material into an emulsifying pot, stirring and homogenizing, uniformly dispersing until no insoluble substances exist, heating to 80-85 ℃, preserving heat for 20min, and beginning to cool;
s2, cooling the emulsifying pot to 45 ℃, sequentially adding the phase C raw material and the preservative, and stirring until the mixture is uniform and no insoluble substances exist;
s3, premixing the phase D raw materials, stirring uniformly and transparently, slowly adding into an emulsifying pot, stirring uniformly, cooling to 38 ℃, after the inspection is qualified, using filter cloth with more than 400 meshes, filtering and discharging to obtain the skin care product gel containing the aloe arborescens.
CN202210018856.6A 2022-01-09 2022-01-09 Composition containing Aloe arborescens Miller and application thereof Pending CN114159371A (en)

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