CN111973501A - Ceramide activation milk and preparation method thereof - Google Patents

Ceramide activation milk and preparation method thereof Download PDF

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Publication number
CN111973501A
CN111973501A CN201911235347.3A CN201911235347A CN111973501A CN 111973501 A CN111973501 A CN 111973501A CN 201911235347 A CN201911235347 A CN 201911235347A CN 111973501 A CN111973501 A CN 111973501A
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component
parts
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weight
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龚杰
杜建华
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Shanghai Yuxin Biotechnology Co ltd
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Shanghai Yuxin Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The invention discloses ceramide activation milk and a preparation method thereof, wherein the ceramide activation milk comprises the following components in parts by weight: the components of 10: 1.5-2.5 parts of ceramide (3) mixture; and (2) component 12: extracting brown algae (PHYLLACANTHA FIBROSA) to obtain mixture 1.5-2.5; a component 13: extracting Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) to obtain mixture 1.5-2.5; component 14: extracting Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit to obtain mixture 1.5-2.5; the components of 15: a split yeast fermentation lysate mixture 1.5-2.5; the components of 16: octyl methicone 1.5 to 2.5; a component 17: acetyl hexapeptide-8 mixture 1.5-2.5; a component 19: 0.8-1.2 parts of sodium hyaluronate mixture; the components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.4-0.6. The invention adopts pure plant extracts as the conditioner, can deeply nourish the skin, and keeps each medicinal preparation in a reasonable range, thereby not only ensuring effective conditioning, but also not generating stronger side effect.

Description

Ceramide activation milk and preparation method thereof
Technical Field
The invention relates to daily chemical articles, in particular to ceramide activation milk and a preparation method thereof.
Background
The activation lotion is used for supplementing moisture to skin, increasing skin elasticity, improving rough and loose skin, smoothing and moistening skin, and softening and moistening skin, and is generally used after face cleaning.
However, most of the active milks with skin conditioning currently adopt chemicals or even antibiotics. Although this method has a fast and good therapeutic effect, it causes imbalance of skin secretion and causes drug resistance and tolerance, so that its side effects are also great. Especially, the existing activated milk products with different shapes and colors cannot be differentiated by consumers due to limited knowledge. Even if the plant formula is marked for storage, the plant formula also has great side effects due to improper selection and proportion of the components.
Disclosure of Invention
In view of the above-mentioned defects of the prior art, the technical problem to be solved by the present invention is to provide a ceramide-activating milk and a preparation method thereof, wherein a plant formula is adopted, and each component is controlled in an effective range, so that the functions of maintenance and conditioning can be achieved, and major side effects can be prevented from being generated.
In order to realize the purpose, the invention provides ceramide activation milk which comprises the following components in parts by weight:
Component 1: 47-51 parts of water
And (2) component: 5-7 parts of glycerin
And (3) component: butanediol 4-6
And (4) component: 3-5 parts of squalane
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 3-5
And (4) component 6: butyrospermum PARKII (Butyrumparkii) fruit fat 2-4
And (4) component 7: isopropyl myristate 2-4
And (4) component 8: cetearyl glucoside 2-4
And (3) component 9: decyl Hoodia oleate 2-4
The components of 10: ceramide (3) mixture 1.5-2.5
The components of (11): tocopherol (vitamin E)1.5-2.5
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extract mixture 1.5-2.5
A component 13: extracting Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) to obtain mixture 1.5-2.5
Component 14: the extract mixture of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit is 1.5-2.5
The components of 15: two split yeast fermentation product lysate mixture 1.5-2.5
The components of 16: octyl methicone 1.5-2.5
A component 17: acetyl hexapeptide-8 mixture 1.5-2.5
The components of 18: carnosine 0.8-1.2
A component 19: 0.8-1.2 parts of sodium hyaluronate mixture
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.4-0.6
The components of 21: 0.4-0.6 of p-hydroxyacetophenone mixture
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.4-0.6
Component 23: glycerol glucoside 0.4-0.6
And (3) component 24: tetrahydro-methyl-pyrimidine-carboxylic acid 0.2-0.4
Component 25: dipotassium glycyrrhizinate 0.2-0.4
The component (26): acrylic acid (ester) crosslinked polymer 0.2-0.4
The components of 27: bisabolol 0.2-0.4
Component 28: EDTA disodium 0.04-0.06
The component (29): 0.004-0.008 of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: 28-32 parts of ceramide (3), 68-72 parts of hydrogenated lecithin;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: 28-32 parts of brown algae (PHYLLACANTHA FIBROSA) extract, 38-42 parts of glycerol and 26-34 parts of water;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: 18-22 parts of Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract, 28-32 parts of butanediol and 46-54 parts of water;
component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: 28-32 parts of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract, 18-22 parts of butanediol and 46-54 parts of water;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: 38-42 parts of schizosaccharomyces cerevisiae fermentation product lysate, 28-32 parts of butanediol and 26-34 parts of water;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-828-32, water 68-72;
A component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: 9-11 parts of sodium hyaluronate and 89-91 parts of water;
the components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: 18-22 parts of p-hydroxyacetophenone, 68-72 parts of isoprene glycol and 6-14 parts of 1, 2-hexanediol;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: 18-22 parts of purslane (Portulaca OLERACEA) extract, 38-42 parts of butanediol and 36-44 parts of water.
The component 1 is used as a solvent for dissolving and mixing the components;
the component 2 is used as humectant, glycerin, softening, moisturizing, makeup removing solvent and lubricant. Undiluted 100% pure glycerol can never be used directly, which would have adverse effects. Glycerol has a water-absorbing effect, and is often used in moisturizing skin care products to absorb water molecules in the air, so that the stratum corneum of the skin covered by the moisturizing skin care product is kept moist.
Component 3 acts as a humectant, and butylene glycol can increase product smoothness, and is widely used in cosmetics, possibly producing a slight irritating sensation, but there is no evidence of sensitization, and both CIR and FDA have so far evaluated this component as safe. The skin care product is commonly used as a micromolecule moisturizing component, can retain water in the horny layer, has good hygroscopicity, can absorb water which is equivalent to 12.5 percent (relative humidity is 50 percent) and 38.5 percent (relative humidity is 80 percent) of the mass of the skin care product, and also has a certain bacteriostatic action.
The component 4 is taken as an emollient, squalane is extracted from deep sea shark liver or olive oil, is a natural component of skin, has good antioxidant capacity and stimulation immunity, can be rapidly dissolved with moisture and grease in the skin to form a natural skin protection barrier, has excellent stability, can not generate oxidation with air, ultraviolet rays and the like, can effectively protect the skin from being damaged by external substances, has excellent permeability and high-efficiency oxygen carrying performance, can adjust the water-oil balance of the skin, avoids rough and dark skin and recovers the original tender touch of the skin. Is especially suitable for cold seasons, is a skin lubricating oil, and can supplement natural sebum of skin.
The component 5 is used as emollient, and jojoba (SIMMONDSIA CHINENSIS) seed oil is not easy to be oxidized, and has high temperature resistance, high pressure resistance and small viscosity change. It is also superior in touch and extensibility to other vegetable oils, has soft and elastic feeling to the skin, and is easily absorbed by the skin, and is an excellent oil, moisturizer and moisturizer in cosmetics.
Component 6 is used as emollient, and is prepared from fruit fat of Butyrospermum PARKII (Butyrospermum PARKII) by extracting from fruit of Butyrospermum PARKII, contains abundant unsaturated fatty acid, and can enhance skin moisture-keeping ability and moisten dry skin, i.e. cutin-damaged skin. Meanwhile, the fluidity of the product can be adjusted, the viscosity can be improved, and the sensory quality and the use skin feeling of the product can be improved.
Component 7 is used as emollient, isopropyl myristate is used as binder, emollient and keratolytic agent in cosmetics, and the product containing the component is easy to apply and has refreshing texture. The component has small molecule, easy penetration, and good cleaning effect for removing makeup.
The component 8 is used as an emulsifier, and the cetearyl glucoside is used as an emulsifier in cosmetics, so that the moisturizing effect of the product can be enhanced, and the texture is fresh and cool.
Component 9 acts as an emollient, decyl jojoba oleate has strong penetration and dissolution ability, and can be used as a carrier for many ester soluble active ingredients. Can be used alone or in combination with other oils for producing emollient oils. Can be used in cosmetic creams, two emulsion type emulsions.
Component 10 acts as an emollient, and its ceramide (3) is a lipid material, a synthetic ingredient, structurally similar to the materials that make up the stratum corneum of the skin, and can rapidly penetrate into the skin, aid in the renewal of the natural protective layer of the skin, promote the balance of natural hydration, and bind with water in the stratum corneum to form a network that retains water. The skin moisturizing and repairing cream has good effects on skin moisturizing and repairing, is an important skin activating component in the horny layer, and can enhance the skin barrier, rebuild cells and form an effective barrier to prevent water loss and reduce the influence of the external environment. More ceramide is particularly needed in irritated skin and it has been shown that rubbing a product containing a ceramide component reduces redness and swelling and loss of moisture through the skin, acting to enhance the skin barrier and help the damaged skin to relieve dry conditions. The hydrogenated lecithin is a partial hydrolysate of lecithin, and the hydrogenated lecithin improves its hydrophilic ability. Can be absorbed by human skin and hair and promote the penetration of other nutrients, and is often used in conditioning cosmetics together with linolenic acid, hyaluronic acid and vitamins, and lecithin has strong emulsifying effect, can stabilize emulsion, and is suitable for preparing gel products.
Component 11 acts as an emollient, tocopherol (vitamin E) is a treatment for two chemicals: the biological effects of both chemical substances in vivo are approximately the same, but the activities are different, as a general term for tocopherols and tocotrienols. There are four types of both tocopherols and tocotrienols: alpha, beta, gamma, and delta, the difference between which is the number and position of methyl groups on the phenol ring; the difference between tocotrienols is in their unsaturated side chains. Tocotrienols (Tocotrienols) belong to the class of vitamin E. Like vitamin E, tocotrienols are also quite potent antioxidants, and are able to combat lipid peroxidation.
Component 12 is used as skin conditioner, and the extract of brown algae (PHYLLACANTHA FIBROSA) mainly contains alginate jelly, vitamins, amino acids, etc. Is a natural moisturizing and softening agent, can promote cell regeneration, has the function of strengthening skin metabolism, has unique function of removing cutin, can refresh skin, and prevents wrinkles.
Component 13 is used as skin conditioner, and its Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract belongs to red algae. Contains multiple vitamins and colloid. Can moisturize, maintain the elasticity of skin, ensure the smoothness and the elasticity of the skin, moisturize and lock water, and nourish the skin.
Component 14 can be used as skin conditioner, and its Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract has heat and toxic materials clearing away, antibacterial, and anti-inflammatory effects.
Component 15 is used as skin conditioner, and the lysate of yeast fermentation product is obtained by culturing, inactivating and decomposing Bacillus bifidus to obtain metabolite, cytoplasm fragment, cell wall component and polysaccharide complex. However, the Chinese name is the lysate of the yeast fermentation product of the second split, which has no relation with yeast, belongs to the behavior of light by the word "yeast", and the extraction process is similar to the lysate of the yeast fermentation product. Has strong immunosuppressive activity, can promote DNA repair, can effectively protect skin from being damaged by ultraviolet rays, is used for skin care, sun protection and after-sun care products of emulsion, water-based and hydroalcoholic systems, and helps to prevent photoaging of epidermis and dermis. The yeast fermentation product lysate can generate small molecules which comprise vitamin B group, minerals, amino acids and the like and are beneficial to skin care, and the yeast essence is high-quality yeast essence only used for skin care. It has effects in promoting metabolism of stratum corneum, capturing free radicals, inhibiting lipid peroxidation, whitening skin, and resisting aging. The product is rich in nutrients, and has skin nourishing effect.
Component 16 acts as an emollient, octyl methicone, which adds texture to the product, making it fresh and easy to apply.
Component 17 acts as a skin conditioner, with acetyl hexapeptide-8 being a bioactive polypeptide that both reduces existing facial wrinkles and effectively prevents new wrinkles from developing. The release of the nerve conduction element acetylcholine (acetylcholine) is inhibited to reduce the contraction of muscles, thereby achieving the purpose of reducing the generation of dynamic lines and expression lines.
Component 18 acts as a skin conditioner and the fibroblast survival time in dilute aqueous solution of carnosine is significantly prolonged, which indicates that carnosine is not only a nutrient but also can promote the metabolism of cells and delay aging. The medicinal cream can be used as wound healing promoter. Carnosine can capture free oxygen free radicals, particularly effectively prevent oxidation of protein components and has a whitening function; can be used together with urocanic acid for preventing light sensitive dermatitis; carnosine is also readily absorbed by the skin, hair and scalp and contributes to penetration.
The component 19 is used as a skin conditioner, sodium hyaluronate of the skin conditioner is also called as sodium hyaluronate, belongs to a skin conditioner, is an acidic mucopolysaccharide, naturally exists in corneal epithelium, can absorb 1000 times of water by the weight of the acidic mucopolysaccharide, so as to achieve the purposes of keeping the water of the skin, preventing the water from losing through the epidermis and repairing a barrier when the skin is damaged, ensure that the skin does not feel dry and increase the luster after being used, improve the skin nutrition metabolism, make the skin soft and smooth, remove wrinkles, increase the elasticity and prevent aging, and is a good transdermal absorption promoter while keeping moisture. The nutrient can be used together with other nutrient components to achieve the more ideal effect of promoting nutrient absorption.
The component 20 is used as skin conditioner, hydrolyzed SCLEROTIUM rolfsii (scleroglucan) gum is natural polymer of polysaccharide, also called scleroglucan, is stable at various pH values under high temperature, is polysaccharide polymer, has good compatibility with skin, can effectively form film, and has stability.
Component 21 is used as solvent for dissolving organic components, wherein p-hydroxyacetophenone is a natural plant extract, and is naturally present in stems and leaves of Artemisia scoparia of Compositae, and roots of Artemisia capillaris Thunb, Asclepiadaceae, and Heteropappus japonicus Thunb. A multifunctional cosmetic ingredient having antioxidant and soothing effects; the preservative can be used as a substitute of the traditional preservative in cosmetics, has the functions of antisepsis and synergism, can promote the efficacy of various preservatives, and has excellent stability in high and low pH and temperature ranges. Can be used in various formulations, including sunscreen and shampoo. It has good compatibility with various cosmetic components and packaging materials. The isoprene glycol is a deodorization component with remarkable effect. Can enhance the antibacterial performance of alcohols and dihydric alcohols and enhance the traditional antiseptic system. Meanwhile, the skin care product has the effects of moisturizing and mildly moisturizing, and can improve the skin feeling of a cosmetic formula. The 1, 2-hexanediol belongs to polyhydric alcohol, has a bacteriostatic effect, and has a preservative effect only when the addition amount is about 5%.
The component 22 is used as skin conditioner, and herba Portulacae (Portulaca OLERACEA) extract has broad-spectrum antibacterial and antiinflammatory effects, and can be used for preventing and treating dermatoses such as skin eczema, allergic dermatitis, and contact dermatitis; the product has good oxygen free radical scavenging ability, which shows that the product has obvious antioxidation function; has good skin moisture keeping effect.
The component 23 is used as humectant, and glyceryl glucoside is a substance formed by combining glycerol and glucose molecule by glycosidic bond, and has moisturizing and antioxidant effects.
The component 24 is used as a skin conditioner, and the tetrahydro-methyl pyrimidine carboxylic acid is also called Ectoin (Ectoin) and exists in halotolerant bacteria as an osmotic pressure compensation solute, plays a chemical transmitter-like role in cells, has a stable protection effect on the cells in adverse environment, can also stabilize the structure of enzyme protein in organisms, and has the functions of activating skin and resisting aging; can provide good moisturizing and sun-screening functions and has the function of whitening the skin; tetrahydromethylpyrimidine carboxylic acids also protect neutrophils and show anti-inflammatory effects.
Component 25 is used as skin conditioner, and dipotassium glycyrrhizinate is glycyrrhizin (glycyrrhizic acid) component of radix Glycyrrhizae root and stem suitable for allergic skin, and has effects of resisting irritation, controlling oil, reducing red swelling, relieving inflammation, and healing. Can effectively prevent sensitive inflammation phenomenon when skin is stimulated. Has the effects of diminishing inflammation and tranquilizing caused by sunshine, and is often used in antiallergic and repairing cosmetics.
Component 26 acts as a thickener and the cross-linked polymer of acrylic acid (ester) type mainly has the function of adsorbing various organic components, thereby forming a viscous product.
The component 27 is used as a skin conditioner, and the bisabolol is extracted from chrysanthemum plants, has the functions of anti-inflammation and bacteriostasis, has good stability and good compatibility with skin, reduces skin inflammation, relieves skin acne, prevents acne, improves the anti-irritation capacity of the skin, repairs the skin with inflammation injury, and improves the SPF value in a sun-screening product. The bisabolol has obvious anti-inflammatory and antispasmodic effects, and on the function, the natural bisabolol has twice of the effects of a synthetic product, has the functions of relieving pain, alleviating irritation and resisting allergy, and has skin care effect on allergic skin or children skin. Bisabolol has sedative and antiperspirancy effects, and is commonly used in sunscreen products and ointments for treating sunburn and burn; has broad-spectrum antibacterial property, and can reduce dental plaque and gingival allergy and prevent and treat halitosis when being used in toothpaste; the bisabolol has high permeability on the skin cortex, and the action of the bisabolol is dozens of times of that of a common penetrant; can be used as main agent or adjuvant for preventing and treating skin diseases such as acne, and also has skin conditioning effect.
Component 28 is used as chelating agent, disodium EDTA has stabilizing effect in cosmetic, and mineral chelating agent has synergistic antiseptic effect. And has a certain synergistic effect on an anticorrosion system and an antioxidant system.
Component 29 acts as a fragrance, which is used to provide a fragrance.
The INCI names for each component are as follows:
Figure BDA0002304726160000091
Figure BDA0002304726160000101
Figure BDA0002304726160000111
the preparation method of the ceramide activation milk comprises the following steps:
s1, sequentially putting the component 1, the component 2, the component 3, the component 21 and the component 28 into a water phase pot of an emulsifying pot, stirring, heating to 80-90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
s2, sequentially putting the component 4, the component 5, the component 6, the component 7, the component 8, the component 9 and the component 11 into an oil phase pot of an emulsifying pot, stirring at the speed of 50 revolutions per minute, heating to 75-80 ℃, and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate into a main emulsifying pot, homogenizing for 5 minutes or more, then pumping into a second intermediate, homogenizing for 5 minutes or more, and preserving heat for 20 minutes or more to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 65-70 ℃, adding the component 19, the component 25, the component 26 and the component 27, homogenizing for 5 minutes or more, and uniformly dissolving to obtain a fourth intermediate;
S4, cooling the fourth intermediate to 55-60 ℃, sequentially adding the component 10 and the component 16, and stirring for dissolving to obtain a fifth intermediate;
s5, cooling the fifth intermediate to 40-45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 15, the component 16, the component 17, the component 18, the component 20, the component 22, the component 23, the component 24 and the component 29, and stirring to dissolve completely to obtain a finished product;
s6, cooling the finished product to 35-40 ℃, stopping stirring, and discharging. The applicant has designed the above preparation method because the components can withstand different temperatures and need to be dissolved and mixed one by one according to the principle of similar solubility. The method can ensure the activity of each component on the premise of ensuring that each component is fully dissolved and mixed, thereby ensuring the efficacy of a final finished product.
The invention has the beneficial effects that: the invention adopts pure plant extracts as the conditioner, can deeply nourish the skin, and keeps each medicinal preparation in a reasonable range, thereby not only ensuring effective conditioning, but also not generating stronger side effect.
The skin care product can keep moisture and moisten, has fresh skin feel, is not sticky, has good moistening degree and long moisture-keeping time, well repairs damaged skin, and in addition, the ceramide is wrapped by the nano coating, so that the skin absorption effect can be better improved, and the ceramide can more effectively permeate into the deep layer of the skin.
Detailed Description
The invention is further illustrated by the following examples:
example one
A ceramide activation milk comprises the following components in parts by weight:
component 1: water 48.045
And (2) component: glycerol 6
And (3) component: butanediol 5
And (4) component: squalane 4
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 4
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3
And (4) component 7: isopropyl myristate 3
And (4) component 8: cetearyl glucoside 3
And (3) component 9: decyl Hoodia oleate 3
The components of 10: ceramide (3) mixture 2
The components of (11): tocopherol (vitamin E)2
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2
A component 13: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture 2
Component 14: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture 2
The components of 15: two split yeast fermentation product lysate mixture 2
The components of 16: octyl methicone 2
A component 17: acetyl hexapeptide-8 mixture 2
The components of 18: carnosine 1
A component 19: sodium hyaluronate mixture 1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.5
The components of 21: p-hydroxyacetophenone mixture 0.5
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.5
Component 23: glycerol glucoside 0.5
And (3) component 24: tetrahydrophylpyrimidine carboxylic acid 0.3
Component 25: dipotassium glycyrrhizinate 0.2
The component (26): acrylic acid (ester) crosslinked Polymer 0.2
The components of 27: bisabolol 0.2
Component 28: EDTA disodium 0.05
The component (29): 0.005 of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)30, hydrogenated lecithin 70;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: 30 parts of brown algae (PHYLLACANTHA FIBROSA) extract, 40 parts of glycerol and 30 parts of water;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract 20, butanediol 30, and water 20;
component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: 30 parts of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract, 20 parts of butanediol and 50 parts of water;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: split yeast fermentation product lysate 40, butanediol 30, water 30;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-830, water 70;
A component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: 10 parts of sodium hyaluronate and 90 parts of water;
the components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: p-hydroxyacetophenone 20, isoprene glycol 70, 1, 2-hexanediol 10;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: herba Portulacae (Portulaca OLERACEA) extract 20, butanediol 40, and water 40.
Example two
A ceramide activation milk comprises the following components in parts by weight:
component 1: water 49
And (2) component: glycerol 5.5
And (3) component: butanediol 4.5
And (4) component: squalane 3.5
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 3.5
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 2.5
And (4) component 7: isopropyl myristate 2.5
And (4) component 8: cetearyl glucoside 2.5
And (3) component 9: decyl Hoodiol oleate 2.5
The components of 10: ceramide (3) mixture 2.2
The components of (11): tocopherol (vitamin E)2.2
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.2
A component 13: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture 2.2
Component 14: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extract mixture 2.2
The components of 15: two split yeast fermentation product lysate mixture 2.2
The components of 16: octyl methicone 2.2
A component 17: acetyl hexapeptide-8 mixture 2.2
The components of 18: carnosine 0.9
A component 19: sodium hyaluronate mixture 0.9
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.45
The components of 21: p-hydroxyacetophenone mixture 0.45
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.45
Component 23: glycerol glucoside 0.45
And (3) component 24: tetrahydrophylpyrimidine carboxylic acid 0.25
Component 25: dipotassium glycyrrhizinate 0.25
The component (26): acrylic acid (ester) crosslinked Polymer 0.25
The components of 27: bisabolol 0.25
Component 28: disodium EDTA 0.055
The component (29): 0.007 parts of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)29, hydrogenated lecithin 71;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 29, glycerol 39, water 32;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract 19, butanediol 29, and water 52;
Component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extract 29, butanediol 19 and water 52;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: split yeast fermentation product lysate 39, butanediol 29, water 32;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-829, water 71;
a component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 9, water 91;
the components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: p-hydroxyacetophenone 19, isoprene glycol 69, 1, 2-hexanediol 12;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: herba Portulacae (Portulaca OLERACEA) extract 19, butanediol 39, and water 42.
EXAMPLE III
A ceramide activation milk comprises the following components in parts by weight:
component 1: 50.5 parts of water
And (2) component: glycerol 6.4
And (3) component: butanediol 5.6
And (4) component: squalane 6
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 4.6
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3.6
And (4) component 7: isopropyl myristate 3.6
And (4) component 8: cetearyl glucoside 3.6
And (3) component 9: decyl Hoodia oleate 3.6
The components of 10: ceramide (3) mixture 18
The components of (11): tocopherol (vitamin E)1.8
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 1.8
A component 13: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture 1.8
Component 14: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture 1.8
The components of 15: two split yeast fermentation product lysate mixture 1.8
The components of 16: octyl methicone 1.8
A component 17: acetyl hexapeptide-8 mixture 1.8
The components of 18: carnosine 1.1
A component 19: sodium hyaluronate mixture 1.1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.56
The components of 21: 0.4-0.6 of p-hydroxyacetophenone mixture
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.56
Component 23: glycerol glucoside 0.56
And (3) component 24: tetrahydrophylpyrimidine carboxylic acid 0.36
Component 25: dipotassium glycyrrhizinate 0.36
The component (26): acrylic acid (ester) crosslinked Polymer 0.36
The components of 27: bisabolol 0.36
Component 28: EDTA disodium 0.056
The component (29): 0.0056 of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)31, hydrogenated lecithin 69;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 31, glycerol 41 and water 28;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract 21, butanediol 31, and water 48;
component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: 31 of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract, 21 of butanediol and 48 of water;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: a split yeast fermentation product lysate 41, butanediol 31, water 28;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-831, water 69;
a component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 11, water 89;
The components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: p-hydroxyacetophenone 21, isoprene glycol 71, 1, 2-hexanediol 8;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: herba Portulacae (Portulaca OLERACEA) extract 21, butanediol 41, and water 38.
Example four
A preparation method of ceramide activation milk comprises the following steps:
s1, sequentially putting the component 1, the component 2, the component 3, the component 21 and the component 28 into a water phase pot of an emulsifying pot, stirring at the speed of 50 revolutions per minute, heating to 90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
s2, sequentially putting the component 4, the component 5, the component 6, the component 7, the component 8, the component 9 and the component 11 into an oil phase pot of an emulsifying pot, stirring at the speed of 50 revolutions per minute, heating to 80 ℃, and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate, pumping into a main emulsifying pot, homogenizing at 3000 r/min, pumping into a second intermediate, homogenizing for 5 min, stirring at 40 r/min, and keeping the temperature for 20 min or more to obtain a third intermediate;
S4, opening cooling water, cooling the third intermediate to 70 ℃, adding the component 19, the component 25, the component 26 and the component 27, homogenizing for 5 minutes at 3000 r/min, and uniformly dissolving to obtain a fourth intermediate;
s4, cooling the fourth intermediate to 60 ℃, sequentially adding the component 10 and the component 16, and stirring for dissolving to obtain a fifth intermediate;
s5, cooling the fifth intermediate to 45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 15, the component 16, the component 17, the component 18, the component 20, the component 22, the component 23, the component 24 and the component 29, and stirring and dissolving completely to obtain a finished product;
and S6, cooling the finished product to 40 ℃, stopping stirring, and discharging.
The invention is not described in detail, but is well known to those skilled in the art.
The foregoing detailed description of the preferred embodiments of the invention has been presented. It should be understood that numerous modifications and variations could be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the prior art according to the concept of the present invention should be within the scope of protection defined by the claims.

Claims (9)

1. The ceramide-activated milk is characterized by comprising the following components in parts by weight:
the components of 10: ceramide (3) mixture 1.5-2.5
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extract mixture 1.5-2.5
A component 13: extracting Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) to obtain mixture 1.5-2.5
Component 14: the extract mixture of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit is 1.5-2.5
The components of 15: two split yeast fermentation product lysate mixture 1.5-2.5
The components of 16: octyl methicone 1.5-2.5
A component 17: acetyl hexapeptide-8 mixture 1.5-2.5
A component 19: 0.8-1.2 parts of sodium hyaluronate mixture
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.4-0.6.
2. The ceramide-activated milk as claimed in claim 2, further comprising the following components in parts by weight:
component 1: 47-51 parts of water
And (2) component: 5-7 parts of glycerin
And (3) component: butanediol 4-6
And (4) component: 3-5 parts of squalane
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 3-5
And (4) component 6: butyrospermum PARKII (Butyrumparkii) fruit fat 2-4
And (4) component 7: isopropyl myristate 2-4
And (4) component 8: cetearyl glucoside 2-4
And (3) component 9: decyl Hoodia oleate 2-4
The components of (11): tocopherol (vitamin E)1.5-2.5
The components of 18: carnosine 0.8-1.2
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.4-0.6
The components of 21: 0.4-0.6 of p-hydroxyacetophenone mixture
Component 23: glycerol glucoside 0.4-0.6
And (3) component 24: tetrahydro methyl pyrimidine carboxylic acid 0.2-0.4.
3. The ceramide-activated milk as claimed in claim 2, further comprising the following components in parts by weight:
component 25: dipotassium glycyrrhizinate 0.2-0.4
The component (26): acrylic acid (ester) crosslinked polymer 0.2-0.4
The components of 27: bisabolol 0.2-0.4
Component 28: EDTA disodium 0.04-0.06
The component (29): 0.004-0.008 of essence.
4. A ceramide-activated milk according to claim 3, characterized by the component 10: the ceramide (3) mixture comprises the following components in parts by weight: 28-32 parts of ceramide (3), 68-72 parts of hydrogenated lecithin;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: 28-32 parts of brown algae (PHYLLACANTHA FIBROSA) extract, 38-42 parts of glycerol and 26-34 parts of water;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: 18-22 parts of Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract, 28-32 parts of butanediol and 46-54 parts of water;
Component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: 28-32 parts of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract, 18-22 parts of butanediol and 46-54 parts of water;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: 38-42 parts of schizosaccharomyces cerevisiae fermentation product lysate, 28-32 parts of butanediol and 26-34 parts of water;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-828-32, water 68-72;
a component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: 9-11 parts of sodium hyaluronate and 89-91 parts of water;
the components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: 18-22 parts of p-hydroxyacetophenone, 68-72 parts of isoprene glycol and 6-14 parts of 1, 2-hexanediol;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: 18-22 parts of purslane (Portulaca OLERACEA) extract, 38-42 parts of butanediol and 36-44 parts of water.
5. The ceramide-activated milk as claimed in claim 4, which is prepared from the following components in parts by weight:
component 1: water 49
And (2) component: glycerol 5.5
And (3) component: butanediol 4.5
And (4) component: squalane 3.5
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 3.5
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 2.5
And (4) component 7: isopropyl myristate 2.5
And (4) component 8: cetearyl glucoside 2.5
And (3) component 9: decyl Hoodiol oleate 2.5
The components of 10: ceramide (3) mixture 2.2
The components of (11): tocopherol (vitamin E)2.2
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.2
A component 13: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture 2.2
Component 14: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extract mixture 2.2
The components of 15: two split yeast fermentation product lysate mixture 2.2
The components of 16: octyl methicone 2.2
A component 17: acetyl hexapeptide-8 mixture 2.2
The components of 18: carnosine 0.9
A component 19: sodium hyaluronate mixture 0.9
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.45
The components of 21: p-hydroxyacetophenone mixture 0.45
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.45
Component 23: glycerol glucoside 0.45
And (3) component 24: tetrahydrophylpyrimidine carboxylic acid 0.25
Component 25: dipotassium glycyrrhizinate 0.25
The component (26): acrylic acid (ester) crosslinked Polymer 0.25
The components of 27: bisabolol 0.25
Component 28: disodium EDTA 0.055
The component (29): 0.007 parts of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)29, hydrogenated lecithin 71;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 29, glycerol 39, water 32;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract 19, butanediol 29, and water 52;
component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extract 29, butanediol 19 and water 52;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: split yeast fermentation product lysate 39, butanediol 29, water 32;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-829, water 71;
a component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 9, water 91;
The components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: p-hydroxyacetophenone 19, isoprene glycol 69, 1, 2-hexanediol 12;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: herba Portulacae (Portulaca OLERACEA) extract 19, butanediol 39, and water 42.
6. The ceramide-activated milk as claimed in claim 4, which is prepared from the following components in parts by weight:
component 1: 50.5 parts of water
And (2) component: glycerol 6.4
And (3) component: butanediol 5.6
And (4) component: squalane 6
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 4.6
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3.6
And (4) component 7: isopropyl myristate 3.6
And (4) component 8: cetearyl glucoside 3.6
And (3) component 9: decyl Hoodia oleate 3.6
The components of 10: ceramide (3) mixture 18
The components of (11): tocopherol (vitamin E)1.8
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 1.8
A component 13: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture 1.8
Component 14: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture 1.8
The components of 15: two split yeast fermentation product lysate mixture 1.8
The components of 16: octyl methicone 1.8
A component 17: acetyl hexapeptide-8 mixture 1.8
The components of 18: carnosine 1.1
A component 19: sodium hyaluronate mixture 1.1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.56
The components of 21: 0.4-0.6 of p-hydroxyacetophenone mixture
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.56
Component 23: glycerol glucoside 0.56
And (3) component 24: tetrahydrophylpyrimidine carboxylic acid 0.36
Component 25: dipotassium glycyrrhizinate 0.36
The component (26): acrylic acid (ester) crosslinked Polymer 0.36
The components of 27: bisabolol 0.36
Component 28: EDTA disodium 0.056
The component (29): 0.0056 of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)31, hydrogenated lecithin 69;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 31, glycerol 41 and water 28;
a component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract 21, butanediol 31, and water 48;
component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: 31 of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract, 21 of butanediol and 48 of water;
The components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: a split yeast fermentation product lysate 41, butanediol 31, water 28;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-831, water 69;
a component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 11, water 89;
the components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: p-hydroxyacetophenone 21, isoprene glycol 71, 1, 2-hexanediol 8;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: herba Portulacae (Portulaca OLERACEA) extract 21, butanediol 41, and water 38.
7. The ceramide-activated milk as claimed in claim 4, which is prepared from the following components in parts by weight:
component 1: water 48.045
And (2) component: glycerol 6
And (3) component: butanediol 5
And (4) component: squalane 4
And (5) component: jojoba (Simmondsia CHINENSIS) seed oil 4
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3
And (4) component 7: isopropyl myristate 3
And (4) component 8: cetearyl glucoside 3
And (3) component 9: decyl Hoodia oleate 3
The components of 10: ceramide (3) mixture 2
The components of (11): tocopherol (vitamin E)2
And (2) component 12: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2
A component 13: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture 2
Component 14: caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture 2
The components of 15: two split yeast fermentation product lysate mixture 2
The components of 16: octyl methicone 2
A component 17: acetyl hexapeptide-8 mixture 2
The components of 18: carnosine 1
A component 19: sodium hyaluronate mixture 1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.5
The components of 21: p-hydroxyacetophenone mixture 0.5
The components of 22: herba Portulacae (Portulaca OLERACEA) extract mixture 0.5
Component 23: glycerol glucoside 0.5
And (3) component 24: tetrahydrophylpyrimidine carboxylic acid 0.3
Component 25: dipotassium glycyrrhizinate 0.2
The component (26): acrylic acid (ester) crosslinked Polymer 0.2
The components of 27: bisabolol 0.2
Component 28: EDTA disodium 0.05
The component (29): 0.005 of essence;
the components of 10: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)30, hydrogenated lecithin 70;
and (2) component 12: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture comprises the following components in parts by weight: 30 parts of brown algae (PHYLLACANTHA FIBROSA) extract, 40 parts of glycerol and 30 parts of water;
A component 13: the Kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract mixture comprises the following components in parts by weight: kappaphycus ALVAREZII (Kappaphycus ALVAREZII) extract 20, butanediol 30, and water 20;
component 14: the Caesalpinia spinosa (CAESALPINIA SPINOSA) fruit extraction mixture comprises the following components in parts by weight: 30 parts of Caesalpinia Spinosa (CAESALPINIA SPINOSA) fruit extract, 20 parts of butanediol and 50 parts of water;
the components of 15: the lysis mixture of the secondary fission yeast fermentation product comprises the following components in parts by weight: split yeast fermentation product lysate 40, butanediol 30, water 30;
a component 17: the acetyl hexapeptide-8 mixture comprises the following components in parts by weight: acetyl hexapeptide-830, water 70;
a component 19: the sodium hyaluronate mixture comprises the following components in parts by weight: 10 parts of sodium hyaluronate and 90 parts of water;
the components of 21: the p-hydroxyacetophenone mixture comprises the following components in parts by weight: p-hydroxyacetophenone 20, isoprene glycol 70, 1, 2-hexanediol 10;
the components of 22: the purslane (Portulaca OLERACEA) extraction mixture comprises the following components in parts by weight: herba Portulacae (Portulaca OLERACEA) extract 20, butanediol 40, and water 40.
8. A preparation method of ceramide activation milk is characterized by comprising the following steps:
s1, sequentially putting the component 1, the component 2, the component 3, the component 21 and the component 28 into a water phase pot of an emulsifying pot, stirring, heating to 80-90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
s2, sequentially putting the component 4, the component 5, the component 6, the component 7, the component 8, the component 9 and the component 11 into an oil phase pot of an emulsifying pot, stirring at the speed of 50 revolutions per minute, heating to 75-80 ℃, and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate into a main emulsifying pot, homogenizing for 5 minutes or more, then pumping into a second intermediate, homogenizing for 5 minutes or more, and preserving heat for 20 minutes or more to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 65-70 ℃, adding the component 19, the component 25, the component 26 and the component 27, homogenizing for 5 minutes or more, and uniformly dissolving to obtain a fourth intermediate;
s4, cooling the fourth intermediate to 55-60 ℃, sequentially adding the component 10 and the component 16, and stirring for dissolving to obtain a fifth intermediate;
s5, cooling the fifth intermediate to 40-45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 15, the component 16, the component 17, the component 18, the component 20, the component 22, the component 23, the component 24 and the component 29, and stirring to dissolve completely to obtain a finished product;
S6, cooling the finished product to 35-40 ℃, stopping stirring, and discharging.
9. The method of claim 8, comprising the steps of:
s1, sequentially putting the component 1, the component 2, the component 3, the component 21 and the component 28 into a water phase pot of an emulsifying pot, stirring at the speed of 50 revolutions per minute, heating to 90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
s2, sequentially putting the component 4, the component 5, the component 6, the component 7, the component 8, the component 9 and the component 11 into an oil phase pot of an emulsifying pot, stirring at the speed of 50 revolutions per minute, heating to 80 ℃, and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate, pumping into a main emulsifying pot, homogenizing at 3000 r/min, pumping into a second intermediate, homogenizing for 5 min, stirring at 40 r/min, and keeping the temperature for 20 min or more to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 70 ℃, adding the component 19, the component 25, the component 26 and the component 27, homogenizing for 5 minutes at 3000 r/min, and uniformly dissolving to obtain a fourth intermediate;
s4, cooling the fourth intermediate to 60 ℃, sequentially adding the component 10 and the component 16, and stirring for dissolving to obtain a fifth intermediate;
S5, cooling the fifth intermediate to 45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 15, the component 16, the component 17, the component 18, the component 20, the component 22, the component 23, the component 24 and the component 29, and stirring and dissolving completely to obtain a finished product;
and S6, cooling the finished product to 40 ℃, stopping stirring, and discharging.
CN201911235347.3A 2019-12-05 2019-12-05 Ceramide activation milk and preparation method thereof Withdrawn CN111973501A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113230194A (en) * 2021-04-16 2021-08-10 敏云(佛山)生物科技有限公司 Facial essence and beautifying method
CN113318056A (en) * 2021-05-28 2021-08-31 广州伊尔美生物科技有限公司 New-born beautifying, firming and wrinkle-removing composition, preparation method thereof and firming and wrinkle-removing cream

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
澳大利亚沃特利制药有限公司: "CEMOY肌底修护精华乳", 《进口普通化妆品备案信息》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113230194A (en) * 2021-04-16 2021-08-10 敏云(佛山)生物科技有限公司 Facial essence and beautifying method
CN113318056A (en) * 2021-05-28 2021-08-31 广州伊尔美生物科技有限公司 New-born beautifying, firming and wrinkle-removing composition, preparation method thereof and firming and wrinkle-removing cream

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