CN111973486A - Ceramide moisturizing and moisture-keeping cream and preparation method thereof - Google Patents

Ceramide moisturizing and moisture-keeping cream and preparation method thereof Download PDF

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CN111973486A
CN111973486A CN201911235196.1A CN201911235196A CN111973486A CN 111973486 A CN111973486 A CN 111973486A CN 201911235196 A CN201911235196 A CN 201911235196A CN 111973486 A CN111973486 A CN 111973486A
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component
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weight
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龚杰
杜建华
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Shanghai Yuxin Biotechnology Co ltd
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Shanghai Yuxin Biotechnology Co ltd
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    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/9706Algae
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    • A61K8/9783Angiosperms [Magnoliophyta]
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Abstract

The invention discloses a ceramide moisturizing cream and a preparation method thereof, wherein the ceramide moisturizing cream comprises the following components in parts by weight: a component 13: 1.8-2.5 of beta-glucan mixture; component 14: 1.8-2.5 parts of ceramide (3) mixture; the components of 15: extracting mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 1.8-2.5; the components of 16: 1-2 parts of sodium hyaluronate mixture; a component 17: extracting root of black mulberry (Morus NIGRA) to obtain mixture 1-2; the components of 18: glycerol glucoside 0.8-1.5; a component 19: tetrahydro-methyl-pyrimidine-carboxylic acid 0.8-1.5; the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture is 0.8-1.5. The invention adopts pure plant extracts as the conditioner, can deeply nourish the skin, and keeps each medicinal preparation in a reasonable range, thereby not only ensuring effective conditioning, but also not generating stronger side effect.

Description

Ceramide moisturizing and moisture-keeping cream and preparation method thereof
Technical Field
The invention relates to daily chemical products, in particular to ceramide moisturizing cream and a preparation method thereof.
Background
The moisturizing cream is a liquid cream cosmetic, which is also called honey cosmetic, is an oil-in-water emulsifier, has a water content of about 20-80%, has certain fluidity and is quite honey-like in shape, and is named. The moisturizing cream has the main functions of decontamination, water supplement and nutrition supplement, or has the functions of controlling skin grease and whitening.
However, most of the existing moisturizing creams with skin conditioning adopt chemicals or even antibiotics. Although this method has a fast and good therapeutic effect, it causes imbalance of skin secretion and causes drug resistance and tolerance, so that its side effects are also great. Especially, the current moisture cream products in different shapes and colors cannot be distinguished by consumers due to limited knowledge. Even if the plant formula is marked for storage, the plant formula also has great side effects due to improper selection and proportion of the components.
Disclosure of Invention
In view of the above defects in the prior art, the technical problem to be solved by the present invention is to provide a ceramide moisturizing cream and a preparation method thereof, wherein a plant formula is adopted, and each component is controlled in an effective range, so that the functions of maintenance and conditioning can be achieved, and large side effects can be prevented from being generated.
In order to achieve the purpose, the invention provides ceramide moisturizing and moisture-preserving cream which comprises the following components in parts by weight:
component 1: 46-50 parts of water
And (2) component: 5-7 parts of glycerin
And (3) component: squalane 4-6
And (4) component: jojoba (Simmondsia CHINENSIS) seed oil 3-5
And (5) component: cetearyl glucoside 2-4
And (4) component 6: butyrospermum PARKII (Butyrumparkii) fruit fat 2-4
And (4) component 7: octyl methicone 2-4
And (4) component 8: isopropyl myristate 2-4
And (3) component 9: tocopherol (vitamin E)1.8-2.5
The components of 10: lecithin 1.8-2.5
The components of (11): 1.8-2.5 portions of dioctyl carbonate
And (2) component 12: aloe extract mixture 1.8-2.5
A component 13: beta-glucan mixture 1.8-2.5
Component 14: ceramide (3) mixture 1.8-2.5
The components of 15: extracting mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 1.8-2.5
The components of 16: sodium hyaluronate mixture 1-2
A component 17: extracting root of black mulberry (Morus NIGRA) to obtain mixture 1-2
The components of 18: glycerol glucoside 0.8-1.5
A component 19: tetrahydro-methyl-pyrimidine-carboxylic acid 0.8-1.5
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.8-1.5
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 0.8-1.5
The components of 22: nicotinamide 0.6-1
Component 23: carnosine 0.6-1
And (3) component 24: acrylic acid (ester) crosslinked polymer 0.4-0.6
Component 25: dipotassium glycyrrhizinate 0.4-0.6
The component (26): 0.4-0.6 of p-hydroxyacetophenone mixture
The components of 27: bisabolol 0.06-0.12
Component 28: 0.008-0.012% of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: 28-32 parts of ceramide (3), 68-72 parts of hydrogenated lecithin;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: 28-32 parts of an extract of an austenitic seaweed (CLADOSIPHON OKAMURANUS), 38-42 parts of glycerin, and 26-34 parts of water;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: 9-11 parts of sodium hyaluronate and 89-91 parts of water;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: 28-32 parts of black mulberry (MORUS NIGRA) root extract, 28-32 parts of 1, 2-hexanediol and 36-46 parts of water;
the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: 38-42 parts of Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, 28-32 parts of butanediol and 26-34 parts of water.
The component 1 is used as a solvent for dissolving and mixing the components;
The component 2 is used as humectant, glycerin, softening, moisturizing, makeup removing solvent and lubricant. Undiluted 100% pure glycerol can never be used directly, which would have adverse effects. Glycerol has a water-absorbing effect, and is often used in moisturizing skin care products to absorb water molecules in the air, so that the stratum corneum of the skin covered by the moisturizing skin care product is kept moist. But the moisturizing effect of pure glycerin is easily affected by the humidity in the air.
The component 3 is taken as an emollient, squalane is extracted from deep sea shark liver or olive oil, is a natural component of skin, has good antioxidant capacity and stimulation immunity, can be rapidly dissolved with moisture and grease in the skin to form a natural skin protection barrier, has excellent stability, can not generate oxidation with air, ultraviolet rays and the like, can effectively protect the skin from being damaged by external substances, has excellent permeability and high-efficiency oxygen carrying performance, can adjust the water-oil balance of the skin, avoids rough and dark skin and recovers the original tender touch of the skin. Is especially suitable for cold seasons, is a skin lubricating oil, and can supplement natural sebum of skin.
The component 4 is used as emollient, and jojoba (SIMMONDSIA CHINENSIS) seed oil is not easy to be oxidized, and has high temperature resistance, high pressure resistance and small viscosity change. It is also superior in touch and extensibility to other vegetable oils, has soft and elastic feeling to the skin, and is easily absorbed by the skin, and is an excellent oil, moisturizer and moisturizer in cosmetics.
The component 5 is used as an emulsifier, and the cetearyl glucoside can enhance the moisturizing effect of the product, has fresh texture, and is often used in cream and sunscreen products.
Component 6 is used as emollient, and is prepared from fruit fat of Butyrospermum PARKII (Butyrospermum PARKII) by extracting from fruit of Butyrospermum PARKII, contains abundant unsaturated fatty acid, and can enhance skin moisture-keeping ability and moisten dry skin, i.e. cutin-damaged skin. Meanwhile, the fluidity of the product can be adjusted, the viscosity can be improved, and the sensory quality and the use skin feeling of the product can be improved.
Component 7 acts as an emollient and octyl methicone is used in cosmetics as a skin conditioner and emollient to add texture to the product, making it fresh and easy to apply.
Component 8 is used as emollient, isopropyl myristate is used as adhesive, emollient and cutin softener, and the product added with the component is easier to apply and has refreshing texture. The component has small molecule, easy penetration, and good cleaning effect for removing makeup. However, excessive use of the component can cause the skin to be coarse, waxy and yellow, and has certain irritation and acne causing property.
Component 9 acts as an emollient, tocopherol (vitamin E) is a treatment for two chemicals: the biological effects of both chemical substances in vivo are approximately the same, but the activities are different, as a general term for tocopherols and tocotrienols. There are four types of both tocopherols and tocotrienols: alpha, beta, gamma, and delta, the difference between which is the number and position of methyl groups on the phenol ring; the difference between tocotrienols is in their unsaturated side chains. Tocotrienols (Tocotrienols) belong to the class of vitamin E. Like vitamin E, tocotrienols are also quite potent antioxidants, and are able to combat lipid peroxidation.
The component 10 is used as emollient, lecithin is mainly extracted from egg yolk and soybean, and is an indispensable substance for human body cells, and if lacking, it can reduce skin cell regeneration ability, resulting in rough skin, wrinkle, etc. Lecithin has moisture retention and antioxidant effects, and can ensure skin regeneration activity by adding the component into cosmetic, and the component has good hydrophilicity and lipophilicity, and can increase skin luster after use.
The component 11 is used as an emollient, and the dioctyl carbonate is used as an additive in a sunscreen product, is colorless and strong in solubility, and is used as a softening agent and a dispersing agent. The composition is easily emulsified, can promote product smearing, can form protective film on skin, and is smooth and non-greasy, and has silky touch.
Component 12 acts as a skin conditioner, and its aloe extract has versatile biological activity and is a cosmetically important additive. The promotion effect of aloe extract on fibrin growth, the inhibition of elastin, the synthesis of collagen and the removal effect of free radicals show that the aloe extract has good skin-activating and anti-aging effects; has effects in promoting cholesterol synthesis, changing sebum composition, reducing gloss, and improving skin softness; it also has antibacterial, antiinflammatory and moisture keeping effects.
The component 13 is used as skin conditioner, the beta-glucan is natural plant collagen, and the beta-glucan is used as skin conditioner and humectant in cosmetics, and has certain anti-allergy and anti-inflammatory effects. The component is water soluble, has good compatibility with most raw materials, has no anaphylaxis, and can improve skin moisture keeping ability. The composition also has antioxidant and skin protecting effects against ultraviolet rays, and can reduce skin wrinkles and improve skin resistance against external injury.
Component 14 acts as an emollient, and its ceramide (3), a lipid material, a synthetic ingredient, structurally similar to the materials that make up the stratum corneum of the skin, rapidly penetrates into the skin, aids in the renewal of the natural protective layer of the skin, promotes the balance of natural hydration, and binds with water in the stratum corneum to form a network that retains water. The skin moisturizing and repairing cream has good effects on skin moisturizing and repairing, is an important skin activating component in the horny layer, and can enhance the skin barrier, rebuild cells and form an effective barrier to prevent water loss and reduce the influence of the external environment. More ceramide is particularly needed in irritated skin and it has been shown that rubbing a product containing a ceramide component reduces redness and swelling and loss of moisture through the skin, acting to enhance the skin barrier and help the damaged skin to relieve dry conditions. The hydrogenated lecithin is a partial hydrolysate of lecithin, and the hydrogenated lecithin improves its hydrophilic ability. Can be absorbed by human skin and hair and promote the penetration of other nutrients, and is often used in conditioning cosmetics together with linolenic acid, hyaluronic acid and vitamins, and lecithin has strong emulsifying effect, can stabilize emulsion, and is suitable for preparing gel products.
The component 15 is used as skin conditioner, the extract of the algae (Cladosphan OKAMURANUS) is rich in nutrition and has health care function, contains chlorophyll a and c, carotene, a plurality of xanthophylls, starch, mannitol, lipid and the like, also contains a large amount of vitamins and inorganic salts (natural antioxidant, anti-aging and whitening components), and is also quite suitable for skin conditioning.
The component 16 is used as a humectant, sodium hyaluronate which is also called as sodium hyaluronate belongs to a skin conditioner, is an acidic mucopolysaccharide, naturally exists in corneal epithelium, can absorb 1000 times of moisture of the corneal epithelium by weight, so as to achieve the purposes of keeping skin moisture, preventing the moisture from losing through epidermis and repairing a barrier when the skin is damaged, ensure that the skin does not feel dry and luster after being used, improve the skin nutrition metabolism, make the skin soft and smooth, remove wrinkles, increase elasticity and prevent aging, and is a good transdermal absorption promoter while keeping moisture. The nutrient can be used together with other nutrient components to achieve the more ideal effect of promoting nutrient absorption.
The component 17 is used as skin conditioner, and contains extract of black mulberry (Morus NIGRA) root containing reducing sugar, pentosan and galactoside, tannin, and flavonoids. Can inhibit elastase, and has antiaging effect; promoting the synthesis of fiber bud cell brain amide and softening and moistening skin; can well prevent and treat acne caused by high androgen; has contraction effect on collagen fiber, and can be used for reducing weight; promoting the activation of luciferase, and showing that the luciferase has anti-inflammatory efficacy; can inhibit tyrosinase activity, and has skin whitening effect.
The component 18 is used as emollient, and the glycerol glucoside is a substance formed by combining glycerol and glucose molecules by glycosidic bonds, and has the functions of moisturizing and resisting oxidation.
The component 19 is used as a skin conditioner, and the tetrahydro-methyl pyrimidine carboxylic acid is also called Ectoin (Ectoin) and exists in halotolerant bacteria as an osmotic pressure compensation solute, plays a chemical transmitter-like role in cells, has a stable protection effect on the cells in adverse environment, can also stabilize the structure of enzyme protein in organisms, and has the functions of activating skin and resisting aging; can provide good moisturizing and sun-screening functions and has the function of whitening the skin; tetrahydromethylpyrimidine carboxylic acids also protect neutrophils and show anti-inflammatory effects.
The component 20 is used as skin conditioner, hydrolyzed SCLEROTIUM rolfsii (scleroglucan) gum is natural polymer of polysaccharide, also called scleroglucan, is stable at various pH values under high temperature, is polysaccharide polymer, has good compatibility with skin, can effectively form film, and has good stability.
Component 21 is used as skin conditioner, and Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract has effects in resisting oxidation, increasing topical estrogen level in cortex, enhancing skin cell metabolism, resisting aging, maintaining skin elasticity and removing wrinkle; has antiinflammatory, antiallergic, soothing and astringent effects; also has good water holding capacity.
The component 22 is used as a skin conditioner, nicotinamide also called vitamin B3 has high safety as a medical ingredient, is also a basic vitamin supplement in clinical dermatology treatment, and is widely used for treating photosensitive dermatitis, acne and the like. The research in recent years proves that the medicine also has good curative effect on the aspects of inhibiting melanin pigmentation, resisting inflammation and the like; based on the characteristics, the application of niacinamide in the field of cosmetics is further extended, and besides the traditional whitening effect, the niacinamide is also used for reducing the generated and precipitated melanin, blocking the transfer of the melanin to surface layer cells, accelerating cell metabolism, accelerating the shedding of melanin keratinocytes and the like. The nicotinamide can maintain the moisture content of the skin and promote microcirculation of the dermis. Niacinamide also greatly reduces or eliminates skin aging phenomena such as wrinkles, scaling, large pores, etc., reduces free radical damage to the skin, and serves to prevent aging, repair skin, and reduce facial darkness.
Component 23 acts as a skin conditioner and the fibroblast survival time in dilute aqueous solutions of carnosine is significantly prolonged, which indicates that carnosine is not only a nutrient but also promotes the metabolism of cells and delays aging. The medicinal cream can be used as wound healing promoter. Carnosine can capture free oxygen free radicals, particularly effectively prevent oxidation of protein components and has a whitening function; can be used together with urocanic acid for preventing light sensitive dermatitis; carnosine is also readily absorbed by the skin, hair and scalp and contributes to penetration.
Component 24 acts as a thickener and the cross-linked polymer of acrylic acid (ester) can adsorb the components, making the finished product viscous.
The component 25 is used as skin conditioner, dipotassium glycyrrhizinate is used as skin conditioner, glycyrrhizin (glycyrrhizic acid) component of root and stem of Glycyrrhrizae radix is suitable for allergic skin, and has effects of resisting irritation and controlling oil, and diminishing inflammation and healing. Can effectively prevent sensitive inflammation phenomenon when skin is stimulated. Has the effects of diminishing inflammation and tranquilizing caused by sunshine, and is often used in antiallergic and repairing cosmetics.
Component 26 is used as solvent, and is p-hydroxyacetophenone, a natural plant extract, which is naturally present in stems and leaves of Artemisia scoparia of Compositae, and roots of Artemisia capillaris Thunb, Asclepiadaceae, and Heteropappus japonicus Thunb. A multifunctional cosmetic ingredient having antioxidant and soothing effects; the preservative can be used as a substitute of the traditional preservative in cosmetics, has the functions of antisepsis and synergism, can promote the efficacy of various preservatives, and has excellent stability in high and low pH and temperature ranges. Can be used in various formulations, including sunscreen and shampoo. It has good compatibility with various cosmetic components and packaging materials. The isoprene glycol is a multifunctional cosmetic additive and is also a deodorizing component with remarkable effect. Can enhance the antibacterial performance of alcohols and dihydric alcohols and enhance the traditional antiseptic system. Meanwhile, the skin care product has the effects of moisturizing and mildly moisturizing, and can improve the skin feeling of a cosmetic formula. The 1, 2-hexanediol humectant belongs to polyhydric alcohol, has a bacteriostatic effect, has a preservative effect only when the addition amount is about 5 percent, and is not equal to a preservative.
The component 27 is used as a skin conditioner, and the bisabolol is extracted from chrysanthemum plants, has the functions of anti-inflammation and bacteriostasis, has good stability and good compatibility with skin, reduces skin inflammation, relieves skin acne, prevents acne, improves the anti-irritation capacity of the skin, repairs the skin with inflammation injury, and improves the SPF value in a sun-screening product. The bisabolol has obvious anti-inflammatory and antispasmodic effects, and on the function, the natural bisabolol has twice of the effects of a synthetic product, has the functions of relieving pain, alleviating irritation and resisting allergy, and has skin care effect on allergic skin or children skin. Bisabolol has sedative and antiperspirancy effects, and is commonly used in sunscreen products and ointments for treating sunburn and burn; has broad-spectrum antibacterial property, and can reduce dental plaque and gingival allergy and prevent and treat halitosis when being used in toothpaste; the bisabolol has high permeability on the skin cortex, and the action of the bisabolol is dozens of times of that of a common penetrant; can be used as main agent or adjuvant for preventing and treating skin diseases such as acne, and also has skin conditioning effect.
Component 28 acts as a fragrance to provide a fragrance.
The INCI names for each component are as follows:
Figure BDA0002304701000000091
Figure BDA0002304701000000101
the preparation method of the ceramide moisturizing cream comprises the following steps:
S1, sequentially putting the component 1, the component 2, the component 21 and the component 26 into an emulsion pot water phase pot, stirring, heating to 80-90 ℃ and keeping for more than 20 minutes to obtain a first intermediate;
s2, sequentially putting the component 3, the component 4, the component 5, the component 6, the component 7, the component 8, the component 9, the component 10 and the component 11 into an oil phase pot, stirring, heating to 75-80 ℃ and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate into the main emulsifying pot, pumping the heated first intermediate into the second intermediate, homogenizing for 5-10 minutes, and preserving the temperature for more than 20 minutes to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 65-70 ℃, adding the component 24, the component 25 and the component, stirring and dissolving to obtain a fourth intermediate;
s5, cooling the fourth intermediate to 55-60 ℃, sequentially adding the component 15 and the component 17, and stirring for dissolving to obtain a fifth intermediate;
s6, cooling the fifth intermediate to 40-45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 16, the component 18, the component 19, the component 20, the component 22, the component 23 and the component 28, and then stirring and completely dissolving to obtain a finished product;
s7, cooling the finished product to 35-38 ℃, stopping stirring, and discharging. The applicant has designed the above preparation method because the components can withstand different temperatures and need to be dissolved and mixed one by one according to the principle of similar solubility. The method can ensure the activity of each component on the premise of ensuring that each component is fully dissolved and mixed, thereby ensuring the efficacy of a final finished product.
The invention has the beneficial effects that: the invention adopts pure plant extracts as the conditioner, can deeply nourish the skin, and keeps each medicinal preparation in a reasonable range, thereby not only ensuring effective conditioning, but also not generating stronger side effect.
The skin care product can moisturize and moisten skin, has fresh skin feel, is not sticky, has good moistening degree and long moisturizing time, and can well repair damaged skin. In addition, the ceramide is wrapped by the nano-particles, so that the skin absorption effect can be better improved, and the ceramide can be more effectively permeated into the deep layer of the skin.
Detailed Description
The invention is further illustrated by the following examples:
example one
A ceramide moisturizing and moisture-preserving cream comprises the following components in parts by weight:
component 1: water 48.59
And (2) component: glycerol 6
And (3) component: squalane 5
And (4) component: jojoba (Simmondsia CHINENSIS) seed oil 4
And (5) component: cetearyl glucoside 3
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3
And (4) component 7: octyl methicone 3
And (4) component 8: isopropyl myristate 3
And (3) component 9: tocopherol (vitamin E)2.2
The components of 10: lecithin 2
The components of (11): carbonic acid dioctyl ester 2
And (2) component 12: aloe vera extract mixture 2
A component 13: beta-glucan mixture 2
Component 14: ceramide (3) mixture 2
The components of 15: extraction mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 2
The components of 16: sodium hyaluronate mixture 1.5
A component 17: black mulberry (Morus NIGRA) root extract mixture 1.5
The components of 18: glycerol glucoside 1
A component 19: tetrahydropyrimidinecarboxylic acids 1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 1
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 1
The components of 22: nicotinamide 0.8
Component 23: carnosine 0.8
And (3) component 24: acrylic acid (ester) crosslinked Polymer 0.5
Component 25: dipotassium glycyrrhizinate 0.5
The component (26): p-hydroxyacetophenone mixture 0.5
The components of 27: bisabolol 0.1
Component 28: 0.01 of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)30, hydrogenated lecithin 70;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: extract of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 30, glycerol 40, and water 30;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: 10 parts of sodium hyaluronate and 90 parts of water;
A component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 30, 1, 2-hexanediol 30, water 40;
the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 40, butanediol 30, and water 30.
Example two
A ceramide moisturizing and moisture-preserving cream comprises the following components in parts by weight:
component 1: water 48
And (2) component: glycerol 6.2
And (3) component: squalane 4.8
And (4) component: jojoba (Simmondsia CHINENSIS) seed oil 4.8
And (5) component: cetearyl glucoside 3.5
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3.5
And (4) component 7: octyl methicone 3.5
And (4) component 8: isopropyl myristate 3.5
And (3) component 9: tocopherol (vitamin E)2.2
The components of 10: lecithin 2.2
The components of (11): carbonic acid dioctyl ester 2.2
And (2) component 12: aloe extract mixture 2.2
A component 13: beta-glucan mixture 2.2
Component 14: ceramide (3) mixture 2.2
The components of 15: extraction mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 2.2
The components of 16: sodium hyaluronate mixture 1.8
A component 17: black mulberry (Morus NIGRA) root extract mixture 1.8
The components of 18: glycerol glucoside 1.2
A component 19: tetrahydropyrimidinecarboxylic acids 1.2
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 1.2
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 1.2
The components of 22: nicotinamide 0.8
Component 23: carnosine 0.8
And (3) component 24: acrylic acid (ester) crosslinked Polymer 0.55
Component 25: dipotassium glycyrrhizinate 0.55
The component (26): p-hydroxyacetophenone mixture 0.55
The components of 27: bisabolol 0.08
Component 28: 0.009 parts of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)29, hydrogenated lecithin 71;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: extract 29 of Austenitic seaweed (CLADOSIPHON OKAMURANUS), glycerol 39, and water 32;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 9, water 91;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 29, 1, 2-hexanediol 29, water 42;
The components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 39, butanediol 29, and water 32.
EXAMPLE III
A ceramide moisturizing and moisture-preserving cream comprises the following components in parts by weight:
component 1: water 49
And (2) component: glycerol 5.5
And (3) component: squalane 4.5
And (4) component: jojoba (SIMMONDSIA CHINENSIS) seed oil 3.8
And (5) component: cetearyl glucoside 3.8
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3.8
And (4) component 7: octyl methicone 3.8
And (4) component 8: isopropyl myristate 3.8
And (3) component 9: tocopherol (vitamin E)2.4
The components of 10: lecithin 2.4
The components of (11): carbonic acid dioctyl ester 2.4
And (2) component 12: aloe extract mixture 2.4
A component 13: beta-glucan mixture 2.4
Component 14: ceramide (3) mixture 2.4
The components of 15: extraction mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 2.4
The components of 16: sodium hyaluronate mixture 1.6
A component 17: black mulberry (Morus NIGRA) root extract mixture 1.6
The components of 18: glycerol glucoside 1.4
A component 19: tetrahydropyrimidinecarboxylic acids 1.4
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 1.4
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 1.4
The components of 22: nicotinamide 0.75
Component 23: carnosine 0.75
And (3) component 24: acrylic crosslinked Polymer 0.48
Component 25: dipotassium glycyrrhizinate 0.48
The component (26): p-hydroxyacetophenone mixture 0.48
The components of 27: bisabolol 0.09
Component 28: 0.012 parts of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)31, hydrogenated lecithin 69;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: extract 31 of Austenitic seaweed (CLADOSIPHON OKAMURANUS), glycerol 41, and water 28;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 11, water 89;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 31, 1, 2-hexanediol 31, water 38;
the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 41, butanediol 31, and water 28.
Example four
The preparation method of the ceramide moisturizing cream comprises the following steps:
s1, sequentially putting the component 1, the component 2, the component 21 and the component 26 into an emulsion pot water phase pot, stirring at the stirring speed of 50 r/min, heating to 90 ℃ and keeping for more than 20 min to obtain a first intermediate;
s2, sequentially putting the component 3, the component 4, the component 5, the component 6, the component 7, the component 8, the component 9, the component 10 and the component 11 into an oil phase pot, stirring at a stirring speed of 50 revolutions per minute, stirring and heating to 80 ℃ and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate, pumping into a main emulsifying pot, homogenizing at 3000 r/min, pumping into a second intermediate, homogenizing for 5 min, stirring at 40 r/min, and preserving heat for more than 20 min to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 70 ℃, adding the component 24, the component 25 and the component, homogenizing for 5 minutes, and homogenizing at 3000 r/min to obtain a fourth intermediate;
s5, cooling the fourth intermediate to 60 ℃, sequentially adding the component 15 and the component 17, and stirring for dissolving to obtain a fifth intermediate;
s6, cooling the fifth intermediate to 45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 16, the component 18, the component 19, the component 20, the component 22, the component 23 and the component 28, and stirring to dissolve completely to obtain a finished product;
And S7, cooling the finished product to 38 ℃, stopping stirring, and discharging.
The invention is not described in detail, but is well known to those skilled in the art.
The foregoing detailed description of the preferred embodiments of the invention has been presented. It should be understood that numerous modifications and variations could be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the prior art according to the concept of the present invention should be within the scope of protection defined by the claims.

Claims (9)

1. The ceramide moisturizing and moisture-preserving cream is characterized by comprising the following components in parts by weight:
a component 13: beta-glucan mixture 1.8-2.5
Component 14: ceramide (3) mixture 1.8-2.5
The components of 15: extracting mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 1.8-2.5
The components of 16: sodium hyaluronate mixture 1-2
A component 17: extracting root of black mulberry (Morus NIGRA) to obtain mixture 1-2
The components of 18: glycerol glucoside 0.8-1.5
A component 19: tetrahydro-methyl-pyrimidine-carboxylic acid 0.8-1.5
The components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture is 0.8-1.5.
2. The ceramide moisturizing and moisture-preserving cream as claimed in claim 1, further comprising the following components in parts by weight:
component 1: 46-50 parts of water
And (2) component: 5-7 parts of glycerin
And (3) component: squalane 4-6
And (4) component: jojoba (Simmondsia CHINENSIS) seed oil 3-5
And (5) component: cetearyl glucoside 2-4
And (4) component 6: butyrospermum PARKII (Butyrumparkii) fruit fat 2-4
And (4) component 7: octyl methicone 2-4
And (4) component 8: isopropyl myristate 2-4
And (3) component 9: tocopherol (vitamin E)1.8-2.5
The components of 10: lecithin 1.8-2.5
The components of (11): 1.8-2.5 portions of dioctyl carbonate
And (2) component 12: aloe extract mixture 1.8-2.5
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.8-1.5
The components of 22: nicotinamide 0.6-1
Component 23: carnosine 0.6-1
And (3) component 24: acrylic acid (ester) crosslinked polymer 0.4-0.6
Component 25: dipotassium glycyrrhizinate 0.4-0.6
The component (26): 0.4-0.6 of p-hydroxyacetophenone mixture
The components of 27: 0.06-0.12 of bisabolol.
3. The ceramide moisturizing and moisture-preserving cream as claimed in claim 2, further comprising the following components in parts by weight:
component 28: 0.008-0.012% of essence.
4. The ceramide moisturizing cream as claimed in claim 3, wherein the weight ratio of component 14: the ceramide (3) mixture comprises the following components in parts by weight: 28-32 parts of ceramide (3), 68-72 parts of hydrogenated lecithin;
The components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: 28-32 parts of an extract of an austenitic seaweed (CLADOSIPHON OKAMURANUS), 38-42 parts of glycerin, and 26-34 parts of water;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: 9-11 parts of sodium hyaluronate and 89-91 parts of water;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: 28-32 parts of black mulberry (MORUS NIGRA) root extract, 28-32 parts of 1, 2-hexanediol and 36-46 parts of water;
the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: 38-42 parts of Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract, 28-32 parts of butanediol and 26-34 parts of water.
5. The ceramide moisturizing and moisture-preserving cream as claimed in claim 4, which is composed of the following components in parts by weight:
component 1: water 48.59
And (2) component: glycerol 6
And (3) component: squalane 5
And (4) component: jojoba (Simmondsia CHINENSIS) seed oil 4
And (5) component: cetearyl glucoside 3
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3
And (4) component 7: octyl methicone 3
And (4) component 8: isopropyl myristate 3
And (3) component 9: tocopherol (vitamin E)2.2
The components of 10: lecithin 2
The components of (11): carbonic acid dioctyl ester 2
And (2) component 12: aloe vera extract mixture 2
A component 13: beta-glucan mixture 2
Component 14: ceramide (3) mixture 2
The components of 15: extraction mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 2
The components of 16: sodium hyaluronate mixture 1.5
A component 17: black mulberry (Morus NIGRA) root extract mixture 1.5
The components of 18: glycerol glucoside 1
A component 19: tetrahydropyrimidinecarboxylic acids 1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 1
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 1
The components of 22: nicotinamide 0.8
Component 23: carnosine 0.8
And (3) component 24: acrylic acid (ester) crosslinked Polymer 0.5
Component 25: dipotassium glycyrrhizinate 0.5
The component (26): p-hydroxyacetophenone mixture 0.5
The components of 27: bisabolol 0.1
Component 28: 0.01 of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)30, hydrogenated lecithin 70;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: extract of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 30, glycerol 40, and water 30;
The components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: 10 parts of sodium hyaluronate and 90 parts of water;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 30, 1, 2-hexanediol 30, water 40;
the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 40, butanediol 30, and water 30.
6. The ceramide moisturizing and moisture-preserving cream as claimed in claim 4, which is composed of the following components in parts by weight:
component 1: water 48
And (2) component: glycerol 6.2
And (3) component: squalane 4.8
And (4) component: jojoba (Simmondsia CHINENSIS) seed oil 4.8
And (5) component: cetearyl glucoside 3.5
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3.5
And (4) component 7: octyl methicone 3.5
And (4) component 8: isopropyl myristate 3.5
And (3) component 9: tocopherol (vitamin E)2.2
The components of 10: lecithin 2.2
The components of (11): carbonic acid dioctyl ester 2.2
And (2) component 12: aloe extract mixture 2.2
A component 13: beta-glucan mixture 2.2
Component 14: ceramide (3) mixture 2.2
The components of 15: extraction mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 2.2
The components of 16: sodium hyaluronate mixture 1.8
A component 17: black mulberry (Morus NIGRA) root extract mixture 1.8
The components of 18: glycerol glucoside 1.2
A component 19: tetrahydropyrimidinecarboxylic acids 1.2
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 1.2
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 1.2
The components of 22: nicotinamide 0.8
Component 23: carnosine 0.8
And (3) component 24: acrylic acid (ester) crosslinked Polymer 0.55
Component 25: dipotassium glycyrrhizinate 0.55
The component (26): p-hydroxyacetophenone mixture 0.55
The components of 27: bisabolol 0.08
Component 28: 0.009 parts of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)29, hydrogenated lecithin 71;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: extract 29 of Austenitic seaweed (CLADOSIPHON OKAMURANUS), glycerol 39, and water 32;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 9, water 91;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 29, 1, 2-hexanediol 29, water 42;
The components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 39, butanediol 29, and water 32.
7. The ceramide moisturizing and moisture-preserving cream as claimed in claim 4, which is composed of the following components in parts by weight:
component 1: water 49
And (2) component: glycerol 5.5
And (3) component: squalane 4.5
And (4) component: jojoba (SIMMONDSIA CHINENSIS) seed oil 3.8
And (5) component: cetearyl glucoside 3.8
And (4) component 6: butyrospermum PARKII (Butyrum PARKII) fruit fat 3.8
And (4) component 7: octyl methicone 3.8
And (4) component 8: isopropyl myristate 3.8
And (3) component 9: tocopherol (vitamin E)2.4
The components of 10: lecithin 2.4
The components of (11): carbonic acid dioctyl ester 2.4
And (2) component 12: aloe extract mixture 2.4
A component 13: beta-glucan mixture 2.4
Component 14: ceramide (3) mixture 2.4
The components of 15: extraction mixture of Austenitic seaweed (CLADOSIPHON OKAMURANUS) 2.4
The components of 16: sodium hyaluronate mixture 1.6
A component 17: black mulberry (Morus NIGRA) root extract mixture 1.6
The components of 18: glycerol glucoside 1.4
A component 19: tetrahydropyrimidinecarboxylic acids 1.4
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 1.4
The components of 21: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract mixture 1.4
The components of 22: nicotinamide 0.75
Component 23: carnosine 0.75
And (3) component 24: acrylic crosslinked Polymer 0.48
Component 25: dipotassium glycyrrhizinate 0.48
The component (26): p-hydroxyacetophenone mixture 0.48
The components of 27: bisabolol 0.09
Component 28: 0.012 parts of essence;
component 14: the ceramide (3) mixture comprises the following components in parts by weight: ceramide (3)31, hydrogenated lecithin 69;
the components of 15: the extractive mixture of the austenitic seaweed (Cladosporon OKAMURANUS) comprises the following components in parts by weight: extract 31 of Austenitic seaweed (CLADOSIPHON OKAMURANUS), glycerol 41, and water 28;
the components of 16: the sodium hyaluronate mixture comprises the following components in parts by weight: sodium hyaluronate 11, water 89;
a component 17: the black mulberry (MORUS NIGRA) root extraction mixture comprises the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 31, 1, 2-hexanediol 31, water 38;
the components of 21: the Hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extraction mixture comprises the following components in parts by weight: hamamelis virginiana (HAMAMELIS VIRGINIANA) leaf extract 41, butanediol 31, and water 28.
8. A preparation method of ceramide moisturizing cream is characterized by comprising the following steps:
s1, sequentially putting the component 1, the component 2, the component 21 and the component 26 into an emulsion pot water phase pot, stirring, heating to 80-90 ℃ and keeping for more than 20 minutes to obtain a first intermediate;
s2, sequentially putting the component 3, the component 4, the component 5, the component 6, the component 7, the component 8, the component 9, the component 10 and the component 11 into an oil phase pot, stirring, heating to 75-80 ℃ and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate into the main emulsifying pot, pumping the heated first intermediate into the second intermediate, homogenizing for 5-10 minutes, and preserving the temperature for more than 20 minutes to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 65-70 ℃, adding the component 24, the component 25 and the component, stirring and dissolving to obtain a fourth intermediate;
s5, cooling the fourth intermediate to 55-60 ℃, sequentially adding the component 15 and the component 17, and stirring for dissolving to obtain a fifth intermediate;
s6, cooling the fifth intermediate to 40-45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 16, the component 18, the component 19, the component 20, the component 22, the component 23 and the component 28, and then stirring and completely dissolving to obtain a finished product;
S7, cooling the finished product to 35-38 ℃, stopping stirring, and discharging.
9. The method of claim 8, comprising the steps of:
s1, sequentially putting the component 1, the component 2, the component 21 and the component 26 into an emulsion pot water phase pot, stirring at the stirring speed of 50 r/min, heating to 90 ℃ and keeping for more than 20 min to obtain a first intermediate;
s2, sequentially putting the component 3, the component 4, the component 5, the component 6, the component 7, the component 8, the component 9, the component 10 and the component 11 into an oil phase pot, stirring at a stirring speed of 50 revolutions per minute, stirring and heating to 80 ℃ and keeping for more than 20 minutes to obtain a second intermediate;
s3, vacuumizing the heated first intermediate, pumping into a main emulsifying pot, homogenizing at 3000 r/min, pumping into a second intermediate, homogenizing for 5 min, stirring at 40 r/min, and preserving heat for more than 20 min to obtain a third intermediate;
s4, opening cooling water, cooling the third intermediate to 70 ℃, adding the component 24, the component 25 and the component, homogenizing for 5 minutes, and homogenizing at 3000 r/min to obtain a fourth intermediate;
s5, cooling the fourth intermediate to 60 ℃, sequentially adding the component 15 and the component 17, and stirring for dissolving to obtain a fifth intermediate;
S6, cooling the fifth intermediate to 45 ℃, sequentially adding the component 12, the component 13, the component 14, the component 16, the component 18, the component 19, the component 20, the component 22, the component 23 and the component 28, and stirring to dissolve completely to obtain a finished product;
and S7, cooling the finished product to 38 ℃, stopping stirring, and discharging.
CN201911235196.1A 2019-12-05 2019-12-05 Ceramide moisturizing and moisture-keeping cream and preparation method thereof Withdrawn CN111973486A (en)

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