CN113576966A

CN113576966A - Composition for cosmetics, preparation method and application thereof

Info

Publication number: CN113576966A
Application number: CN202110872924.0A
Authority: CN
Inventors: 黄丽勤; 黄丽琨; 黄立珊
Original assignee: Changsha Daixi Biological Technology Co ltd
Current assignee: Changsha Daixi Biological Technology Co ltd
Priority date: 2021-06-08
Filing date: 2021-07-30
Publication date: 2021-11-02
Anticipated expiration: 2041-07-30
Also published as: CN113576966B

Abstract

The invention relates to the field of cosmetics, and discloses a composition for cosmetics as well as a preparation method and application thereof. The composition comprises cinerea jecorina essential oil and a liposome inclusion, wherein the content of the liposome inclusion in the composition is 100-130 parts by weight relative to 100 parts by weight of the cinerea jecorina essential oil. The composition provided by the invention utilizes the synergistic compatibility of the cinnamon shadow essential oil and the liposome inclusion in a specific ratio to obtain the composition with excellent anti-saccharification and anti-oxidation effects, when the composition is used in cosmetics, no modifier, skin feel improver or high-volatility silicone oil and high-polarity oil are needed to be added, the composition still has the characteristics of light and moist skin feel and no thick and heavy greasy feel, can be absorbed through skin, does not float oil, and has a comfortable Q-elastic and moist skin feel and a good anti-aging effect.

Description

Composition for cosmetics, preparation method and application thereof

Technical Field

The invention relates to the field of cosmetics, in particular to a composition for cosmetics and a preparation method and application thereof.

Background

The pursuit of modern women for facial skin care is extremely strong, and the skin care requirements tend to be subdivided, specialized and precise. The traditional four-piece skin care set, such as face cleaning, toner, lotion and cream, can not meet the requirements of modern women, and facial essence, a high-activity and high-efficiency skin care product, is more and more emphasized in the middle-high-end skin care market.

The facial essence includes water essence, oil-in-water essence, water-in-oil essence, and oil essence. The water essence and the oil-in-water essence have the problems of low active matter absorption and utilization rate and poor efficiency, the water-in-oil essence needs to be added with an emulsifier and a preservative, the skin barrier can be weakened after long-term use, and in addition, in order to pursue good skin feeling, the existing pure oil system can be added with high-polarity synthetic ester and high-volatility silicone oil to meet the refreshing and non-greasy requirements of customers, but the components cannot solve the root problem and have certain stimulation effect on sensitive and fragile skin.

Therefore, there is an urgent need to develop a pure natural non-irritating active composition and to achieve the maximum assurance that the active composition is actually absorbed and utilized transdermally, and to obtain a highly active and highly effective facial essence that improves skin quality from the root.

Disclosure of Invention

The invention aims to overcome the defects of low absorption and utilization rate of active matters and irritation of a facial essence product in the prior art, and provides a composition for cosmetics, a preparation method and application thereof.

In order to achieve the above objects, the present invention provides a composition for cosmetics, comprising cinnamon shadow essential oil and liposome inclusion, wherein the liposome inclusion is contained in an amount of 100-130 parts by weight relative to 100 parts by weight of the cinnamon shadow essential oil;

the cinnamon shadow essential oil comprises the following components in percentage by weight: 0.1-0.8: 0.1-0.6: 0.1-0.6 of flos Osmanthi Fragrantis extract, flos Magnoliae oil, Myrrha oil, and Olibanum oil;

the liposome inclusion comprises, by taking the total weight of the liposome inclusion as a reference, 5-10 wt% of carnosine, 5-10 wt% of decarboxylated carnosine, 1-5 wt% of ferulic acid, 1-5 wt% of lysine, 1-5 wt% of resveratrol, 1-5 wt% of arginine, 0.5-2 wt% of licoflavone, 40-60 wt% of water, 3-8 wt% of phospholipid and 10-30 wt% of glycerol.

The second aspect of the present invention provides the use of a composition for cosmetics as described above in cosmetics.

In a third aspect, the present invention provides a method for preparing a composition for cosmetics, the method comprising: mixing the phase A component and the phase B component;

the phase A component contains jojoba seed oil, caprylic capric triglyceride, squalane, dipalmitoyl hydroxyproline, glycyrrhetinic stearate, phytosterol ester, dimethyl methoxy hydrocinnamoyl dihydropyranyl alcohol, glycolipid and tetrahydrocurcumin;

the phase B component contains liposome lipoic acid, peony seed oil, cucumber seed oil, watermelon seed oil, perilla seed oil, tocotrienols, liposome inclusion and cinnamon shadow essential oil;

relative to 100 parts by weight of the cinerea extract oil, the using amount of the liposome inclusion is 130 portions by weight of 100-130 portions by weight, the using amount of the glycolipid is 15-30 portions by weight, the using amount of the peony seed oil is 630 portions by weight of 610-1050 portions by weight, the using amount of the watermelon seed oil is 630 portions by weight of 610-630 portions by weight, the using amount of the perilla seed oil is 3200-3280 portions by weight, the using amount of the tocotrienol is 130 portions by weight of 110-130 portions by weight, the using amount of the dimethyl methoxy hydrocinnamoyl dihydropyranol is 4-10 portions by weight, the using amount of the tetrahydrocurcumin is 10-15 portions by weight, the using amount of the jojoba seed oil is 2920-2980 portions by weight, the using amount of the caprylic/capric triglyceride is 1050 portions by weight, and the using amount of the squalane is 2100-2130 portions by weight, the dosage of the dipalmitoyl hydroxyproline is 130-100 parts by weight, the dosage of the stearic acid glycyrrhetinate is 10-15 parts by weight, the dosage of the phytosterol ester is 280-240 parts by weight, and the dosage of the liposome lipoic acid is 150-100 parts by weight;

The composition provided by the invention utilizes the synergistic compatibility of the cinnamon shadow essential oil and the liposome inclusion in a specific ratio to obtain the composition with excellent anti-saccharification and anti-oxidation effects, when the composition is used in cosmetics, no modifier, skin feel improver or high-volatility silicone oil and high-polarity oil are needed to be added, the composition still has the characteristics of light and moist skin feel and no thick and heavy greasy feel, can be absorbed through skin, does not float oil, and has a comfortable Q-elastic and moist skin feel and a good anti-aging effect.

Drawings

FIG. 1 is a graph comparing facial textures of subjects before and after 3 weeks using the essential oil of example 1;

FIG. 2 is a comparison of the red areas on the face of the subjects before and after 3 weeks using the essential oil of example 1;

fig. 3 is a graph comparing facial wrinkles of subjects before and after 3 weeks using the essential oil of example 1.

Detailed Description

The endpoints of the ranges and any values disclosed herein are not limited to the precise range or value, and such ranges or values should be understood to encompass values close to those ranges or values. For ranges of values, between the endpoints of each of the ranges and the individual points, and between the individual points may be combined with each other to give one or more new ranges of values, and these ranges of values should be considered as specifically disclosed herein.

It should be noted that, in various aspects of the present invention, the present invention is described only once in one aspect thereof without repeated description with respect to the same components in the aspects, and those skilled in the art should not be construed as limiting the present invention.

It should be noted that in the present invention, the raw materials that are not described can be obtained from general commercial sources, and those skilled in the art can purchase the raw materials according to needs, and in the present invention, detailed description is omitted.

As described above, the first aspect of the present invention provides a composition for cosmetics, which comprises cinnamon shadow essential oil and liposome inclusion, wherein the liposome inclusion is contained in an amount of 100-130 parts by weight relative to 100 parts by weight of the cinnamon shadow essential oil;

Preferably, the osmanthus flower grape provided by the inventionExtracting with supercritical CO₂And (4) obtaining by an extraction process. The inventors of the present invention found that a specific amount of supercritical CO is added₂The osmanthus flower extract obtained by the extraction process is used in a cosmetic composition together with a specific amount of magnolia flower oil, myrrh oil and frankincense oil, can be directly absorbed through skin, effectively inhibits elastase and collagenase, promotes cell regeneration, and enhances skin immunity, thereby achieving excellent anti-aging effect.

The magnolia flower oil, myrrh oil and frankincense oil can be obtained by adopting a conventional extraction process, and are not described again.

Preferably, the liposome inclusion body is a composite nano preparation, the obtaining mode of the liposome inclusion body is not particularly limited in the invention, and the liposome inclusion body only needs to contain active components such as carnosine, decarboxylated carnosine, ferulic acid, lysine, resveratrol, arginine, licoflavone, water, phospholipid, glycerol and the like required by the invention. The skilled person can prepare themselves or obtain them commercially. For example, the liposome inclusion body is prepared by the following method, which specifically comprises the following steps:

(1) firstly mixing carnosine, decarboxylated carnosine, lysine, arginine, water and glycerol to obtain a first mixed solution;

(2) mixing ferulic acid, resveratrol and ethanol for the second time to obtain a mixed solution II;

(3) thirdly mixing the mixed solution I and the mixed solution II to obtain a mixed solution III;

(4) fourthly mixing the phospholipid and the third mixed solution at 40-50 ℃, and removing the ethanol in the solution by vacuum evaporation at 1330-1350Pa to obtain a fourth mixed solution;

(5) fifthly, mixing the mixed solution IV with a PBS buffer solution to obtain a mixed solution V;

(6) mixing the mixed solution five with a PBS buffer solution for the sixth time to obtain a mixed solution six;

(7) and homogenizing the mixed solution six, and filtering and sterilizing.

In the present invention, the specific operations of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing and the sixth mixing are not particularly limited, and those skilled in the art can perform the operations by using the processes known in the art, and preferably, each of the mixing is performed by using a stirring method. Wherein the conditions of agitation in each of said mixing, independently of each other, preferably comprise: the rotation speed is 40-60rpm, and the time is 40-60 min.

The concrete operation of the six homogenization of the mixed solution in the invention is not particularly limited, and those skilled in the art can perform the process known in the art, preferably, the homogenization is performed in a high-pressure homogenizer, and the homogenization conditions include: the rotation speed is 2000-2500rpm, and the time is 5-10 min.

The specific operation of the filtration sterilization in the present invention is not particularly limited, and those skilled in the art can perform the operation by using a technique known in the art, and preferably, the conditions for the filtration sterilization include: filter sterilized through a 0.22 μm microfiltration membrane.

The carnosine, the decarboxylated carnosine, the ferulic acid, the lysine, the resveratrol, the arginine, the licoflavone, the phospholipid and the glycerol can be obtained commercially and are not described in detail herein.

The inventor finds that when a certain amount of cinnamon shadow essential oil and liposome inclusion are used in a compounding manner in the research process, the cinnamon shadow essential oil has proper comfortable moisturizing and barrier repairing effects when being used for cosmetics, particularly facial skin, can be completely absorbed, does not float oil, and has good anti-saccharification and anti-oxidation effects.

Preferably, the liposome inclusion comprises 8-10 wt% carnosine, 8-10 wt% decarboxylated carnosine, 1-3 wt% ferulic acid, 1-3 wt% lysine, 1-3 wt% resveratrol, 1-3 wt% arginine, 0.5-1.5 wt% licoflavone, 40-50 wt% water, 5-8 wt% phospholipid and 15-30 wt% glycerol based on the total weight of the liposome inclusion. In the preferred range, the permeability of the cell membrane can be improved, and the osmotic absorption and utilization of active substances in the system are facilitated.

Preferably, the phospholipid is soybean lecithin or egg yolk lecithin. In this preferable range, the production cost can be effectively reduced.

The inventor finds that the liposome inclusion formed by lecithin can be well fused with epidermal cells of a human body in cosmetics, promotes transdermal absorption of active substances and improves bioavailability of the active substances in the research process.

Preferably, the composition further comprises glycolipids, and the content of the glycolipids in the composition is 15-30 parts by weight relative to 100 parts by weight of the cinnamon shadow essential oil. In the research process, the inventor finds that the specific amount of the cinerea jecorice essential oil, the liposome inclusion and the glycolipid are compounded for use, so that the activity of the composition can be improved, and the lasting moisturizing effect can be achieved.

Particularly preferably, the glycolipid according to the invention has a purity of 95% by weight or more, and can be obtained by purification after fermentation of olive oil by yeast, with CAS number: no. 1264282-45-2; preferably, in the present invention, the glycolipid can be obtained commercially, for example, the glycolipid of the present invention is purchased from CERAMELA-HG of Toyobo Co., Japan. In the case of the preferred source, the inventors have found that the composition is effective in reducing the loss of moisture through the skin, increasing the moisture content of the stratum corneum of the lip skin, and reducing the phenomena of dryness and itching of the skin.

Preferably, the composition further comprises peony seed oil, cucumber seed oil, watermelon seed oil and perilla seed oil, wherein in the composition, relative to 100 parts by weight of the cinerea extract oil, the content of the peony seed oil is 630 parts by weight, the content of the cucumber seed oil is 1050 parts by weight, the content of the watermelon seed oil is 630 parts by weight, and the content of the perilla seed oil is 3200 parts by weight and 3280 parts by weight. The composition contains specific amounts of peony seed oil, cucumber seed oil, watermelon seed oil and perilla seed oil, so that the scheme of the invention not only endows the product with excellent effects of oxidation resistance, inflammation diminishing, bacteria resistance and the like, but also can relieve and calm the skin and enhance the immunity of the skin; in addition, the permeability of cell membranes can be improved, and the osmotic absorption and utilization of active substances in a system are facilitated.

Preferably, the peony seed oil, the cucumber seed oil, the watermelon seed oil and the perilla seed oil adopt the supercritical CO₂And (4) obtaining by an extraction process. The invention adopts specific amount of supercritical CO₂The peony seed oil, the cucumber seed oil, the watermelon seed oil, the perilla seed oil and other vegetable oils obtained by the extraction process replace the common refined vegetable oil, mineral oil, high-volatility silicone oil and high-polarity synthetic ester in cosmetics, so that allergic contact dermatitis caused by eczema-like lesions of human skin caused by petroleum extracts is avoided, and the infiltrating injury caused by long-term use of the high-volatility silicone oil and the high-polarity synthetic ester is also avoided, so that the composition is milder and safer.

Preferably, the composition also contains tocotrienols, dimethylmethoxy chromanol and tetrahydrocurcumin, and relative to 100 parts by weight of the cinerea extract oil, the content of the tocotrienols is 110-130 parts by weight, the content of the dimethylmethoxy chromanol is 4-10 parts by weight, and the content of the tetrahydrocurcumin is 10-15 parts by weight. The inventor finds that a system with excellent anti-saccharification and anti-oxidation effects can be constructed by compounding specific amounts of cinnamon shadow essential oil, liposome inclusion, tocotrienol, dimethyl methoxy hydrocinnamoyl alcohol and tetrahydrocurcumin, so that the anti-saccharification and anti-oxidation properties in the system are exerted to the utmost extent, and the anti-aging effect of the system is improved.

Preferably, the tocotrienol is tocotrienol of Japan.

In the invention, the structural formula of the dimethyl methoxy hydrocinnamopyranol is shown in the specification

The dimethylmethoxychromanol obtained from this source enables compositions to be obtained with excellent antioxidant properties.

Preferably, the tetrahydrocurcumin in the present invention is tetrahydrocurcumin having a purity of 96% by weight or more, which can be obtained commercially, for example, tetrahydrocurcumin available from sabina usa. The tetrahydrocurcumin obtained from the source has strong anti-inflammatory and antibacterial properties, and can be used for cleaning and nourishing skin, inhibiting collagenase, protecting integrity of collagen from being damaged, and inhibiting melanin generation.

Preferably, the composition further comprises auxiliary materials, wherein the auxiliary materials comprise jojoba oil, caprylic capric triglyceride, squalane, dipalmitoyl hydroxyproline, stearic acid glycyrrhetinate, phytosterol ester and liposome lipoic acid.

Preferably, in the composition, relative to 100 parts by weight of the cinerea essential oil, the content of the jojoba seed oil is 2920-80 parts by weight, the content of the caprylic/capric triglyceride is 1000-1050 parts by weight, the content of the squalane is 2100-2130 parts by weight, the content of the dipalmitoyl hydroxyproline is 100-130 parts by weight, the content of the stearic glycyrrhetinic ester is 10-15 parts by weight, the content of the phytosterol ester is 240-280 parts by weight, and the content of the liposome lipoic acid is 100-150 parts by weight.

In the present invention, the cosmetic composition containing the above-mentioned components in specific amounts can satisfy the effects of anti-glycation, anti-oxidation and moisture retention.

Preferably, in the composition, relative to 100 parts by weight of the cinerea essential oil, the content of the jojoba seed oil is 2950-. Under the condition of a preferable range, the composition of the invention has better anti-saccharification, anti-oxidation and moisturizing effects.

Preferably, the jojoba seed oil is commercially available cold pressed virgin jojoba seed oil from lebao kang VANTAGE, usa.

In the present invention, squalane refers to squalane extracted from sucrose by a biological fermentation technique, and is commercially available. For example, sucrose squalane from NikkO Chemicals, Japan.

In the invention, the dipalmitoyl hydroxyproline has the following structural formula:

preferably, the dipalmitoyl hydroxyproline in the protocol of the invention is purchased from DPHP of seobike, france.

Preferably, the glycyrrhetinic stearate is glycyrrhetinic stearate of japan pill.

Preferably, the phytosterol ester is an alcohol ester obtained by reacting sterol with oleic acid, wherein the sterol is at least one selected from beta sitosterol, stigmasterol, campesterol and brassicasterol.

The present invention does not require any particular method of operation for obtaining alcohol esters from sterols reacted with oleic acid, and those skilled in the art can perform this method by using various methods known in the art.

Preferably, the sterol is extracted from at least one natural material selected from pine, soybean, and rapeseed. Preferably, the phytosterol ester is selected from Healthful Biotech

Of phytosterol esters, Vitae Naturals

At least one of S Esterified phytosterol esters and BESTEROL-E phytosterol esters of TS-BIOTECH. The phytosterol esters in this preferred source provide the composition with uv resistance while also having good anti-inflammatory and long-lasting moisturizing effects.

The composition for cosmetics in the preferred case of the present invention does not contain an aqueous phase, and further contains antioxidants such as tocotrienols, dimethylmethoxychromanol, and several natural plant essential oils such as sweet osmanthus flower extract, magnolia flower oil, frankincense oil and myrrh oil, wherein the frankincense and the myrrh have natural preservative efficacy, and potential damage and irritation of chemical preservatives are avoided.

As mentioned above, the second aspect of the present invention provides a cosmetic composition for use in cosmetics.

The cosmetic may be a cosmetic conventional in the art, and for example, may be at least one of cream, eye cream, neck cream, essence, essential oil, and mask.

As previously mentioned, a third aspect of the present invention provides a method for preparing a composition for cosmetics, the method comprising: mixing the phase A component and the phase B component;

Preferably, said mixing of said a phase component and said B phase component comprises:

(1) mixing the components in the phase A at 70-85 ℃ to obtain a material a;

(2) mixing II the material a with the components of the B phase at 40-50 ℃, and then filtering.

The order and method of adding the components of phase a are not particularly limited, as long as the components of phase a are dissolved to obtain the material a in a solution state.

The order and method of adding the components of phase B are not particularly limited, as long as the components of phase B are dissolved in water. Preferably, tocotrienols, jojoba oil, sweet osmanthus essential oil, perilla seed oil, cucumber seed oil and watermelon seed oil are added first. The long-time heating of the vegetable oils rich in polyunsaturated fatty acids is shortened as much as possible.

In the present invention, in the step (2), the method of mixing the material a with the components in the phase B may not be particularly limited, and preferably, the mixing is performed by a homogenizing and stirring method. Among them, the condition of homogenization may be a condition conventional in the art, and preferably, the condition of homogenization preferably includes: the rotation speed is 2000-2500rpm, and the time is 5-10 min.

Among them, the conditions of stirring preferably include: the rotation speed is 40-60rpm, and the time is 40-60 min.

In the present invention, in the above steps, in order to ensure aseptic conditions, it is preferable to use sterile water or to use water after sterilizing it.

In the present invention, in order to ensure the quality of the cosmetic, the obtained cosmetic may be subjected to post-treatment, for example, filtration, sterilization, packaging treatment, and the like. In the present invention, the method of filtration may be a method conventionally employed in the art. In the present invention, the sterilization method may be a method conventionally used in the art, and may be, for example, high temperature sterilization.

The present invention will be described in detail below by way of examples.

In each 100g of osmanthus fragrans essential oil used in the following examples, the content of the osmanthus fragrans flower extract is 50g, the content of the magnolia oil is 20g, the content of the myrrh oil is 15g, and the content of the mastic oil is 15 g.

The osmanthus flower extract is obtained by adopting the extraction process of extracting osmanthus oil by using supercritical carbon dioxide fluid in CN111254017A in example 1.

The magnolia oil was obtained using the extraction process of example 1 in CN 105441189A.

The myrrh oil and the frankincense oil are obtained by adopting the following extraction process, and the specific steps are as follows: putting the frankincense and myrrh powder into an extraction kettle, adding entrainer absolute ethyl alcohol, wherein the adding amount is as follows: adding 150ml of anhydrous ethanol into every 400g of medicinal powder, and setting CO₂The flow is 22kg/h, the pressure is 35MPa, the temperature is 55 ℃, and the extraction time is 2 h; after the extraction was completed, the extract was collected.

The peony seed oil is obtained by adopting the supercritical extraction method of the peony seed essential oil in CN105018232A in example 1.

The watermelon seed oil is obtained by adopting the supercritical extraction method of the watermelon seed oil in CN104962387A in example 1.

The cucumber seed oil is obtained by a supercritical extraction method similar to that of watermelon seed oil, except that cucumber seeds are replaced by cucumber seeds.

The perilla seed oil adopts the supercritical CO of example 1 in CN104611124A₂The extraction method is used for obtaining.

The jojoba seed oil is commercially available cold pressed virgin jojoba seed oil from VANTAGE of Laibaoka, USA.

The caprylic capric triglyceride is a great British product, and has a model number of (CRODAMOL GTCC-LQ- (SG).

Squalane is sucrose squalane, a commercial product of NikkO CHEMICAL, Japan.

Dipalmitoyl hydroxyproline is commercially available as DPHP from seebeck, france.

Stearyl glycyrrhetinate is a commercially available product of Nippon Bolus.

The phytosterol ester is a commercial product of Healthful Biotech

A phytosterol ester.

The tetrahydrocurcumin is Sabiwhite of tetrahydrocurcumin of Sabinsa, USA.

The dimethylmethoxychromanol is CHROMABRIGHT molecule (ES291) produced by LIPOTEC Spanish.

The glycolipid is CERAMELA-HG from Toyobo Co, Japan.

The liposome lipoic acid is Nanoactive ALA of Purui biological medicine.

Tocotrienols are commercially available from Japan.

In the following examples, the weight of each component is based on the amount of the raw material added.

Example 1 to example 6

This example illustrates the composition for cosmetics according to the present invention essential oils R1 to R6 were formulated according to the following method according to formulation a1 to a6 in table 1. The method comprises the following steps:

(1) mixing the components in the phase A at 80 ℃ to obtain a material a;

(2) and (3) mixing the material a and the components in the phase B at 45 ℃ by adopting a homogenizing and stirring mode II, wherein the homogenizing condition comprises the following steps: the rotating speed is 2500rpm, the time is 8min, and the stirring conditions comprise: the rotation speed was 50rpm for 60min, and then filtered.

Wherein the liposome inclusion comprises 10 wt% of carnosine, 10 wt% of decarboxylated carnosine, 2 wt% of ferulic acid, 2 wt% of lysine, 2 wt% of resveratrol, 2 wt% of arginine, 1 wt% of licoflavone, 45 wt% of water, 6 wt% of phospholipid and 20 wt% of glycerol based on the total weight of the liposome inclusion.

TABLE 1

Example 7

This example illustrates a composition for cosmetics according to the present invention essential oil R7 was formulated according to formulation R1 and the method described in example 1, except that essential oil R7 was prepared using 1g of tocopherol, carvacrol, usa, instead of tocotrienol, in example 1.

Example 8

This example illustrates a composition for cosmetics according to the invention essential oil R8 was formulated according to formulation R1 and the method described in example 1, except that instead of glycyrrhetinate stearate in example 1, 0.05g of MONTANOV 68 (cetearyl alcohol and cetearyl glucoside), french cypress and 0.05g of SIMULSOL 165 (glyceryl stearate and PEG-100 stearate), french cypress were used to prepare essential oil R8.

Comparative example 1

This comparative example is for illustrating the composition for cosmetics according to the present invention essential oil DR1 was formulated according to formulation R1 and the method described in example 1, except that 50g of rose essential oil was used instead of the osmanthus flower extract in example 1, to prepare essential oil DR 1.

Comparative example 2

This comparative example illustrates a composition for cosmetics according to the present invention essential oil DR2 was formulated according to formulation R1 and the method described in example 1, except that rosemary essential oil 15g and patchouli essential oil 15g were used instead of the myrrh oil and the mastic oil, respectively, in example 1, to prepare essential oil DR 2.

Comparative example 3

This comparative example illustrates a composition for cosmetics according to the present invention essential oil DR3 was formulated according to formulation R1 and the method described in example 1, except that 20 wt% carnosine, 2 wt% silymarin, 2 wt% arginine, 2 wt% glucosamine, 2 wt% naringin, 1 wt% citrus fruit extract, 45 wt% water, 6 wt% phospholipid, and 20 wt% glycerin were used instead of the liposome-encapsulated active ingredient in example 1, to prepare essential oil DR 3.

Test example 1: measurement of physical and chemical Properties

And measuring the physicochemical property of the essential oil according to the national standard GB/T26516-2011.

The test results show that the essential oils R1-R11 prepared in the previous examples and comparative examples have good sensory indexes and are transparent and limpid oil liquid; standing at 45 deg.C for 24 hr, and recovering to room temperature to obtain golden yellow atomized oil solution; the essence oil is placed at the temperature of minus 16 ℃ for 24 hours, is still golden yellow fog-like oil after the room temperature is recovered, and after cold resistance and heat resistance, the using effect and the state of the essence oil have no obvious adverse effect, all microbial indexes reach the standard, and therefore, the essence oil prepared by the method has good heat resistance and cold resistance.

Test example 2: evaluation of anti-aging efficacy

The essential oils prepared in the examples and comparative examples were tested in 220 subjects, 20 subjects per essential oil, who were healthy women (i.e., non-allergic constitution) and had an age between 35 and 65, and were mainly characterized by facial skin aging, appearance of wrinkles and spots, large pores, and uneven skin color.

The use method comprises the following steps: after cleaning the face every day, the face is smeared with a proper amount of essential oil once in the morning and at night and continuously used for 9 weeks.

The specific detection method comprises the following steps: after 10 minutes of intervals of face cleaning, the subjects collected facial images of the subjects using a skin image and beauty management system Visia (model Generation 7, Canfield Scientific Co., U.S.A.), collected facial images of the subjects before and after 3, 6 and 9 weeks of use of the essential oil, analyzed and recorded the numbers of features such as spots, wrinkles, textures, pores, brown stains, red zones and purple on the faces of the subjects based on the facial images collected each time, and calculated the respective improvement rates of spots, wrinkles, textures, pores, brown stains, red zones and purple. The results are shown in tables 2 to 3.

In table 2, the feature numbers of spots, textures, pores and red areas are the average values of the feature numbers of T areas and two cheeks of the face of all subjects, the feature number of wrinkles is the average value of the feature number of canthus under one eye of the face of all subjects, and the feature numbers of brown spots and purple are the average values of the feature numbers of one cheek and nose of the face of all subjects.

Wherein, the calculation formula of the speckle improvement rate is as follows: { (number of blotchy features on face of subject before use of essential oil-number of blotchy features on face of subject after 9 weeks use of essential oil)/number of blotchy features on face of subject before use of essential oil } × 100%;

the calculation formula of the wrinkle improvement rate is as follows: { (number of wrinkles feature on face of subject before essential oil was used-number of wrinkles feature on face of subject after 9 weeks using essential oil)/number of wrinkles feature on face of subject before essential oil was used } × 100%;

the calculation formula of the texture improvement rate is as follows: { (number of texture features of face of subject before use of essential oil-number of texture features of face of subject after 9 weeks using essential oil)/number of texture features of face of subject before use of essential oil } × 100%;

the calculation formula of the pore improvement rate is as follows: { (sum of pore characteristics of the face of the subject before use of essential oil-number of pores of the face of the subject after 9 weeks use of essential oil)/number of pores of the face of the subject before use of essential oil } × 100%;

the formula for calculating the improvement rate of the brown stain is as follows: { (number of brown patches feature on face of subject before essential oil-number of brown patches feature on face of subject after 9 weeks using essential oil)/number of brown patches feature on face of subject before essential oil } × 100%;

the red area improvement rate is calculated by the formula: { (red zone feature number of subject's face before essential oil was used-red zone feature number of subject's face after 9 weeks using essential oil)/red zone feature number of subject's face before essential oil was used } × 100%;

the calculation formula of the purpurin improvement rate is as follows: { (purple characteristic number of face of subject before use of essential oil-purple characteristic number of face of subject after 9 weeks use of essential oil)/purple characteristic number of face of subject before use of essential oil } × 100%.

Table 2: the facial features of the subject, such as spots, wrinkles, texture, pores, brown stain, red zone and purple

Table 2 (continuation 1): the facial features of the subject, such as spots, wrinkles, texture, pores, brown stain, red zone and purple

Table 3: rate of improvement

As can be seen from tables 2 and 3, the essential oil formed by the composition provided by the present invention has the effects of significantly reducing or eliminating wrinkles, shrinking pores, smoothing and increasing skin elasticity, having no oily feeling, lightening skin color, moisturizing, etc. after being continuously used for 9 weeks. Meanwhile, in the using process, the safety is high, and only one subject has slight allergy.

In addition, the present invention exemplarily provides facial images collected by a skin test instrument Visia before and after a subject continuously uses the essential oil of example 1 for 3 weeks, as shown in fig. 1 to 3.

Fig. 1 is a graph comparing facial textures of subjects before and after 3 weeks using the essence oil of example 1, fig. 2 is a graph comparing facial red regions of subjects before and after 3 weeks using the essence oil of example 1, and fig. 3 is a graph comparing facial wrinkles of subjects before and after 3 weeks using the essence oil of example 1.

As can be seen from fig. 1 to 3, the essential oil formed by the composition provided by the invention can remarkably reduce or reduce wrinkles, improve skin inflammation and improve plumpness and smoothness of skin after being continuously used for 3 weeks.

The preferred embodiments of the present invention have been described above in detail, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, many simple modifications can be made to the technical solution of the invention, including combinations of various technical features in any other suitable way, and these simple modifications and combinations should also be regarded as the disclosure of the invention, and all fall within the scope of the invention.

Claims

1. A composition for cosmetics, characterized in that the composition comprises cinnamon shadow essential oil and liposome inclusion, wherein the liposome inclusion is contained in the composition in an amount of 100-130 parts by weight relative to 100 parts by weight of the cinnamon shadow essential oil;

2. The composition for cosmetics according to claim 1, wherein the liposome inclusion comprises 8-10 wt% carnosine, 8-10 wt% decarboxylated carnosine, 1-3 wt% ferulic acid, 1-3 wt% lysine, 1-3 wt% resveratrol, 1-3 wt% arginine, 0.5-1.5 wt% licoflavone, 40-50 wt% water, 5-8 wt% phospholipid, and 15-30 wt% glycerol, based on the total weight of the liposome inclusion;

preferably, the phospholipid is soybean lecithin or egg yolk lecithin.

3. The composition for cosmetics according to claim 1 or 2, further comprising a glycolipid in an amount of 15-30 parts by weight relative to 100 parts by weight of the cinnamon shadow essential oil;

preferably, the glycolipid is CERAMELA-HG from Toyobo Co, Japan.

4. The composition for cosmetics according to any one of claims 1 to 3, further comprising peony seed oil, cucumber seed oil, watermelon seed oil and perilla seed oil, wherein in the composition, the content of the peony seed oil is 630-610 parts by weight, the content of the cucumber seed oil is 1050-1000 parts by weight, the content of the watermelon seed oil is 630-610 parts by weight and the content of the perilla seed oil is 3200-80 parts by weight, relative to 100 parts by weight of the cinerea essential oil.

5. The composition for cosmetics according to any one of claims 1 to 4, further comprising tocotrienols, dimethylmethoxychromanol and tetrahydrocurcumin, wherein the tocotrienols are contained in the composition in an amount of 110-130 parts by weight, the dimethylmethoxychromanol is contained in an amount of 4-10 parts by weight, and the tetrahydrocurcumin is contained in an amount of 10-15 parts by weight, relative to 100 parts by weight of the cinnamon essential oil;

preferably, the tocotrienol is tocotrienol constructed in japan;

preferably, the tetrahydrocurcumin is tetrahydrocurcumin having a purity of 96 wt% or more.

6. The composition for cosmetics according to any one of claims 1 to 5, wherein the composition further comprises adjuvants including jojoba oil, caprylic/capric triglyceride, squalane, dipalmitoyl hydroxyproline, glycyrrhetinate stearate, phytosterol esters, liposomal lipoic acid;

7. The composition for cosmetics according to claim 6, wherein, in the composition, relative to 100 parts by weight of the cinerea essential oil, the content of jojoba seed oil is 2950-;

preferably, the jojoba seed oil is commercially available cold pressed virgin jojoba seed oil from lebao kang VANTAGE;

preferably, the squalane is sucrose squalane of NikkO CHEMICAL, Japan;

preferably, the dipalmitoyl hydroxyproline is DPHP from seebeck, france;

8. The composition for cosmetics according to claim 6 or 7, wherein the phytosterol ester is an alcohol ester obtained by reacting a sterol with oleic acid, the sterol being at least one selected from the group consisting of β -sitosterol, stigmasterol, campesterol, brassicasterol;

preferably, the sterol is extracted from at least one natural material selected from pine, soybean, and rapeseed.

9. Use of the composition for cosmetics according to any one of claims 1 to 8 in cosmetics.

10. A method of preparing a composition for use in cosmetics, the method comprising: mixing the phase A component and the phase B component;

the liposome inclusion contains, by taking the total weight of the liposome inclusion as a reference, 5-10 wt% of carnosine, 5-10 wt% of decarboxylated carnosine, 1-5 wt% of ferulic acid, 1-5 wt% of lysine, 1-5 wt% of resveratrol, 1-5 wt% of arginine, 0.5-2 wt% of licoflavone, 40-60 wt% of water, 3-8 wt% of phospholipid and 10-30 wt% of glycerol;

(1) mixing the components in the phase A at 70-85 ℃ to obtain a material a;