CN109260075A - A kind of anti-acne opsonic water - Google Patents
A kind of anti-acne opsonic water Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61P17/10—Anti-acne agents
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- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
The invention discloses a kind of anti-acne opsonic waters, include acne-removing composition A；Weight percentage of the acne-removing composition A in the anti-acne opsonic water is 0.4~0.6%；The acne-removing composition A includes Radix Salviae Miltiorrhizae root extract, cloves alabastrum extract, radix scutellariae root extract, Angelica roots, licorice root extract and Gotu Kola P.E.The present invention cooperates basic material, anti-acne opsonic water is made, can open skin pore by adding mild plant extraction ingredient, the water and oil balance for maintaining skin improves the hair follicle keratinization of skin, removes small pox, desalinate acne print, repairs impaired skin, restore skin natural health state.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of anti-acne opsonic water.
Background technique
With the development of economy with the continuous improvement of quality of life, the anti-acne of Chinese whelk patient is realized to be improved year by year.
Chinese skin disease association, the joint investigation of adolescents in China federation are the results show that the disease incidence of China's whelk is in rise year by year
The problem of trend, 80% or more young people encountered whelk to some extent, the state of an illness it is more serious account for the 1/3 of young people with
On.
Acne is being commonly called as acne, is called " whelk ", " dark sore " or " acne ", is due to hair follicle and sebum adenemphraxis, hair
A kind of skin disease that inflammation is caused.When puberty, intracorporal hormone can stimulate hair growth, promote smegma more heavy wool
Therefore rouge, hair and sebaceous glands accumulate many substances, since this symptom is common in youth of both sexes, so just it is referred to as " the youth
Acne ".
Whelk is a kind of common chronic dermatosis, and juvenile onset number highest is mainly in face and chest and back, table
It is now the various skin injuries such as blackhead, papule, running sore, tubercle, tumour and scar, hinders appearance.The main reason of green whelk
It is that the clogging of pores as caused by the accumulation of sebum causes sebum to accumulate the acne to be formed, once infection occur will be very short
Appearance deterioration forms serious tumour in time or this is abscess.
Acne itself is not fearful, and maximum harm is not in time or acne print, acne hole, acne are easily left in irregular treatment
Scar seriously affects image.Acne hole acne scar be really inflammation invasion plus with hand squeeze the equivalent damage epidermis of skin, skin corium with
And the subcutaneous tissue of more lower section, cause the generation of the destruction of skin, the defect of tissue and scar.These problems not only serious shadow
Appearance is rung, is also acquired a certain degree of difficulty in the treatment.
So for small pox crowd, in order to completely remove small pox acne print, in addition to paying attention to diet, living habit,
A safely and effectively product for resolving poxes is essential.
Summary of the invention
A kind of anti-acne opsonic water is provided it is an object of the invention to overcome the shortcomings of the prior art place.
To achieve the above object, the technical scheme adopted by the invention is as follows: a kind of anti-acne opsonic water, include acne-removing composition A；
Weight percentage of the acne-removing composition A in the anti-acne opsonic water is 0.4~0.6%；The acne-removing composition A packet
Root extract containing Radix Salviae Miltiorrhizae, cloves alabastrum extract, radix scutellariae root extract, Angelica roots, licorice root extract and centella
Extract.
The present invention uses above-mentioned acne-removing composition A, and Radix Salviae Miltiorrhizae root extract has effects that antibacterial, oil-control, anti-inflammatory, angelica root
Extract has the effect of activating microcirculation and removing stasis medicinal, improves follicular keratosis, and licorice root extract and Gotu Kola P.E have reconciliation, repair
The effect of, and cloves alabastrum extract and radix scutellariae root extract can promote Radix Salviae Miltiorrhizae root extract, Angelica roots, licorice
The Transdermal absorption of extract and Gotu Kola P.E etc. dredges pore, to realize " safely, effectively " anti-acne.Acne-removing composition A
It has the following characteristics that and 1) inhibits 5α-reductase activity, balance sebum secretion；2) inhibit acne correlation pathogen in hair follicle sebum
All living creatures is long, inhibiting bacteria and diminishing inflammation；3) good suppression acne activity, skin acne state caused by improving because of cosmetics；4) by promoting to inhale thoroughly
It receives, dredging pore, improve three kinds of approach collaboration promotion acne-removings of follicular keratosis.
The acne-removing composition A can realize the effect of its anti-acne in opsonic water using above-mentioned additive amount, reach efficient benefit
Purpose.
Preferably, in the acne-removing composition A each component parts by weight are as follows: 10~20 parts of Radix Salviae Miltiorrhizae root extract, lilac
2~4 parts of flower bud extract, 1~3 part of radix scutellariae root extract, 1~3 part of Angelica roots, 0.5~2 part of licorice root extract and product
Avenge careless 0.5~2 part of extract.
It is highly preferred that in the acne-removing composition A each component parts by weight are as follows: 15 parts of Radix Salviae Miltiorrhizae root extract, cloves bud
3 parts of extract, 2 parts of radix scutellariae root extract, 2 parts of Angelica roots, 1 part of licorice root extract and 1 part of Gotu Kola P.E.Respectively
When its extract uses said ratio, each extract can be made to give full play to respective effect.
Preferably, the opsonic water also includes acne-removing composition B；The acne-removing composition B is in the anti-acne opsonic water
Weight percentage be 0.4~0.6%；The acne-removing composition B includes herba hedyotis diffusae extract, honeysuckle extract and small
Fruit Chinese honey locust seed extract.
Herba hedyotis diffusae extract has anti-inflammatory and antibacterial action, all has different degrees of antibacterial to coccus and bacillus and kills
Bacterium effect；Caulis lonicerae has antibacterial and antiinflammation, has apparent Antibacterial Activity to S. aureus L-forms and propionibacterium acnes.Institute
Each extract cooperation of acne-removing composition B is stated, there is significant inhibiting effect to 5α-reductase, acne symptom can be mitigated, desalinate
Acne print, while having effects that oil-control.Acne-removing composition B and acne-removing composition A cooperate jointly, can effectively mitigate small pox, help thin
Born of the same parents live again, and repair impaired cell tissue, and activation fibr tissue is rebuild, and it is smoothly fine and smooth to go back skin, smooth it is coarse, keep the skin wet and
Nutrition enables skin softness, water moisten, is flexible, realizes that small pox is eliminated completely.And the acne-removing composition B in opsonic water using upper
Stating additive amount can realize that it desalinates the effect of acne print, realize the efficient utilization of composition B.
Preferably, in the acne-removing composition B each component parts by weight are as follows: 2~4 parts of herba hedyotis diffusae extract, honeysuckle
0.5~2 part of 2~4 parts of extract and fruitlet Chinese honey locust seed extract.When its each extract uses said ratio, each extraction can be made
Object gives full play to respective effect.
It is highly preferred that in the acne-removing composition B each component parts by weight are as follows: 3 parts of herba hedyotis diffusae extract, honeysuckle mention
Take 1 part of 3 parts of object and fruitlet Chinese honey locust seed extract.
Preferably, the opsonic water also includes Fructus psidii guajavae immaturus extract 0.14~0.26%.Fructus psidii guajavae immaturus extract has
The effect of antiphlogistic antibacterial, is cooperated jointly using above-mentioned additive amount and acne-removing composition A and acne-removing composition B and plays its effect.
Preferably, the opsonic water also includes skin-active ingredient；The skin-active ingredient includes niacinamide；The niacinamide is in institute
Stating the weight percentage in opsonic water is 1~2%.
Niacinamide can infiltrate thoroughly cuticula with Cucumber Extract, promote skin to acne-removing composition A, acne-removing composition B and kind
The absorption of the plant extracts such as pomegranate berry extract cork tree extract, improves hair follicle keratinization, and have the function of oil-control
Effect.
Preferably, the opsonic water also includes moisturizer；The moisturizer include propylene glycol, glycerol, ethoxy urea and thoroughly
Bright matter acid sodium.
Preferably, the opsonic water also includes emulsifier；The emulsifier is Cremophor RH40.
Preferably, the opsonic water also includes preservative；In the opsonic water, the preservative includes that weight percent contains
Measure the methyl hydroxybenzoate for 0.08~0.12%, bis- (methylol) imidazolidinyls that weight percentage is 0.1185~0.158%
The iodine propilolic alcohol butyl mephenesin Carbamate that urea and weight percentage are 0.0015~0.002%.
Preferably, the opsonic water includes the component of following weight percentage: acne-removing composition A 0.4~0.6%, being dispelled
Acne composition B 0.4~0.6%, Fructus psidii guajavae immaturus extract 0.14~0.26%, niacinamide 1~2%, glycerol 3.2~4.8%,
Propylene glycol 1.8~2.8%, ethoxy urea 0.7~1.3%, Sodium Hyaluronate 0.014~0.026%, Cremophor RH40
0.013~0.027%, methyl hydroxybenzoate 0.08~0.12%, Bis(hydroxymethyl)imidazolidinyl urea 0.1185~0.158% and iodine third
Alkynol butyl mephenesin Carbamate 0.0015~0.002%.There is deep layer oil-control, anti-inflammatory and desalination acne using the opsonic water of said ratio
The effect of print.
It is highly preferred that the opsonic water includes the component of following weight percentage: acne-removing composition A 0.5%, anti-acne
Composition B 0.5%, Fructus psidii guajavae immaturus extract 0.2%, niacinamide 1.5%, glycerol 4%, propylene glycol 3.21%, ethoxy urea
1%, Sodium Hyaluronate 0.02%, Cremophor RH40 0.02%, methyl hydroxybenzoate 0.1%, bis- (methylol) imidazolidinyls
Urea 0.14% and iodine propilolic alcohol butyl mephenesin Carbamate 0.00175%.It is best using the opsonic water anti-acne effect of above-mentioned formula.
Opsonic water of the present invention is in addition to said components clearly require, in the range of lossless effect of the invention,
Other adjunct ingredients, such as pH adjusting agent, essence, pigment etc. can be added or used to, those skilled in the art can be according to routine
Standard selects common content.
The beneficial effects of the present invention are: the present invention provides a kind of anti-acne opsonic waters, and the present invention is by adding mildly
Plant extraction ingredient cooperates basic material, anti-acne opsonic water is made, can open skin pore, maintains the water and oil balance of skin, changes
The hair follicle keratinization of kind skin, removes small pox, desalinates acne print, repairs impaired skin, restores skin natural health state.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Examples 1 to 9
Examples 1 to 9 is the embodiment of anti-acne opsonic water of the present invention, and anti-acne opsonic water described in Examples 1 to 6 is matched
Fang Jianbiao 1.The formula of the anti-acne opsonic water of embodiment 7~9 is shown in Table 2.In Examples 1 to 9, each component in acne-removing composition A
Parts by weight are as follows: 15 parts of Radix Salviae Miltiorrhizae root extract, 3 parts of cloves alabastrum extract, 2 parts of radix scutellariae root extract, Angelica roots 2
Part, 1 part of licorice root extract and 1 part of Gotu Kola P.E；The parts by weight of each component in acne-removing composition B are as follows: oldenlandia diffusa
1 part of 3 parts of extract, 3 parts of honeysuckle extract and fruitlet Chinese honey locust seed extract.
The preparation method of anti-acne opsonic water described in Examples 1 to 9 the following steps are included:
S1, Jiang Shui, glycerol, ethoxy urea, Sodium Hyaluronate, Fructus psidii guajavae immaturus extract, niacinamide, methyl hydroxybenzoate and the third two
Alcohol throwing is heated with stirring to 85 DEG C, keeps the temperature 20 minutes, and then stirring is cooled to 50 DEG C；
S2, by Bis(hydroxymethyl)imidazolidinyl urea, iodine propilolic alcohol butyl mephenesin Carbamate, and solubilising is to transparent anti-acne group
It closes object A, acne-removing composition B, Melaleuca alternifolia leaf oil and Cremophor RH40 to be added, be stirred until homogeneous；
S3, room temperature is dropped to, is discharged after the assay was approved up to the anti-acne opsonic water.
The formula of anti-acne opsonic water described in 1 Examples 1 to 6 of table
Comparative example 1,2
Comparative example 1, the 2 anti-acne opsonic waters formula be shown in Table 2.The parts by weight of each component in acne-removing composition B are as follows: white flower
1 part of 3 parts of HERBA HEDYOTIS DIFFUSAE extract, 3 parts of honeysuckle extract and fruitlet Chinese honey locust seed extract.Comparative example 1,2 anti-acne opsonic waters
The preparation method is the same as that of Example 1~and 9.
2 embodiment 7~9 of table, comparative example 1, the 2 anti-acne opsonic waters formula
Through examining Examples 1 to 9, comparative example 1,2 products to meet the pertinent regulations requirement of QB/T 1857-2004, sense organ refers to
Mark (color, fragrance, structure) meets industry regulation, and physical and chemical index (pH, heat-resisting, cold-resistant, active matter) meets industry regulation.
Embodiment 10
Product Safety evaluates (experiment of human skin patch)
One, trial target: the anti-acne opsonic water that Examples 1 to 9, comparative example 1,2 are prepared into
Tested crowd's number: 110 people, women
Age: between 12~30 years old
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Grouping: 11 groups, every group of 10 people, average age 25 ± 2 years old.
Two, patch method: selecting qualified spot tester, with closed patch experiment method, by tested material about 0.020g~
For 0.025g drop in spot tester, external application special adhesive tape is covered on subject back, and tested material is removed after 24 hours, after removing respectively
0.5, observation dermoreaction in 6,12,24,48 hours, records its knot according to dermoreaction grade scale in " cosmetics health specification "
Fruit.
Three, experimental result: human skin patch test result is shown: each group subject passes through Examples 1 to 9, comparative example
1, the patch test of the 2 anti-acne opsonic waters, in observation dermoreaction in 0.5,6,12,24,48 hour, wherein 0 skin occurs
It is safe to illustrate that the anti-acne opsonic water uses for adverse reaction.
Embodiment 11
Fungistatic effect test
One, test material
1, test strain: propionibacterium acnes (ATCC6919).
2, test specimen: press S1, S2, S3, S4, S5, S6, S7, S8, D1, D2 sample, 4 DEG C of storages are spare, wherein S1, S2,
S3, S4, S5, S6, S7, S8, D1, D2 respectively correspond the proportion of Examples 1 to 8 and the anti-acne ingredient in comparative example 1,2.
3, culture medium: propionibacterium acnes culture medium, adjusting pH is 6.6~7.0.Agar wherein is added in solid medium
15g/L。
Two, test method
1, bacteria suspension preparation and inoculation: take freezing bacteria suspension 0.1mL in 5mL propionibacterium acnes fluid nutrient medium
In, in 37 DEG C of anaerobic condition culture 2d, to test bacteria suspension.
2, prepared by medical fluid: S1, S2, S3, S4, S5, S6, S7, S8, D1, D2 being used respectively normal saline dilution dense at testing
Degree 0.1%, then gradient dilution respectively.For the first time test gradient dilution concentration be respectively 100% (sample stoste), 50%,
25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%.Test repetition measurement gradient dilution concentration is respectively for the second time
10%, 8%, 6%, 4%, 2%.
3, prepared by bacterium solution: diluting bacteria suspension with propionibacterium acnes fluid nutrient medium, makes its final bacteria concentration l06CFU/
mL。
4, culture and result interpretation: 100 μ L of bacterium solution and 100 μ L of medical fluid is added in micropore, while setting the feminine gender that bacterium is not added
The normal growth control of medical fluid is compareed and is not added, every kind of medicine does 3 in parallel, is averaged.It sets 37 DEG C of anaerobism to be incubated for, be seen after 48h
Examine result.Using muddiness is visually determined whether, data are read using direct method.As a result the premise judged is that growth control is good,
Blank control asepsis growth is clear, and other holes are increased with drug concentration gradient and the growth of bacterium is suppressed.
Table 3 first time antibacterial gradient test result
Note: wherein "+" representative has bacterium growth, and "-" represents nothing.
Second of table 4 antibacterial gradient test result
Note: wherein "+" representative has bacterium growth, and "-" represents nothing.
5, result
From 3 result of table as it can be seen that Examples 1 to 6,8 0.1% solution, be diluted to 12.5% concentration or more at it,
To propionibacterium acnes there is a good inhibiting effect, and embodiment 7 can be only achieved effect in 25% dilution or more, comparative example
It is more than 1 50% concentration of needs.From 4 result of table as it can be seen that the Mlc of Examples 1 to 6 can reach in 10% dilution, implement
The Mlc of example 1 can reach fungistatic effect in 6% diluted concentration.From the above results, anti-acne ingredient of the present invention is most
Low addition about 0.01% can basically reach the effect for inhibiting propionibacterium acnes, and anti-acne ingredient of the present invention is used and dispelled
When acne composition A, acne-removing composition B and Fructus psidii guajavae immaturus extract are used in conjunction with, have than using when one of or two kinds use
There is stronger fungistatic effect.
Embodiment 12
Clinical test is carried out to Examples 1 to 9 and comparative example 1,2 opsonic waters, specific as follows:
Number: 110 people are divided into 11 groups, every group of 10 people, male to female ratio 1:1, and face has acne
Time: 21 days
Position: face
Sample: opsonic water described in Examples 1 to 9 and comparative example 1
Evaluation: (photo is not shown) is evaluated and is taken pictures in progress according to GAGS point-score:
GAGS point-score is Doshi etc. the 1997 acne comprehensive classification system Global Acne Grading proposed
System (GAGS) is a kind of scoring method, has the characteristics that accurate, consistency is strong, quick and overall assessment effect is good.Specifically
Are as follows: according to the density of pilosebaceous unit, distribution and approximate area, acne predilection site is divided into 6 areas: Ith area, forehead, II
Area: right cheek, IIIth area: left cheek, IVth area: nose, V area Xia Ke of area, VIth area: chest and upper back.Ith area, IIth area, III area's factor score value
It is 2, IVth area, V area's factor score value are 1, and VI area's factor score value is 3, and each region skin lesion score value is that (principle is local most serious
Skin lesion determine the score value in the area): 0=is without skin lesion；1 >=1 acne；2 >=1 papules；3 >=1 running sores；4 >=1 tubercles.
Area's total score=factor score value × skin lesion score value, the sum of variant dermatotome total score are comprehensive scores.
Evaluation result is shown in Table 5.
The GAGS score evaluation result of opsonic water described in 5 Examples 1 to 9 of table and comparative example 1
| Group | Before use | 3 days | 7 days | 14 days | 21 days |
| Embodiment 1 | 18.8 | 15.3* | 12.5** | 10.8** | 7.3** |
| Embodiment 2 | 18.4 | 16.0* | 15.5** | 13.5** | 10.9** |
| Embodiment 3 | 18.8 | 17.0* | 15.3** | 13.5** | 11.5** |
| Embodiment 4 | 19.0 | 16.3* | 15.0** | 12.3** | 9.3** |
| Embodiment 5 | 18.6 | 16.6* | 14.1** | 12.1** | 9.9** |
| Embodiment 6 | 17.5 | 15.5* | 13.0** | 12.9** | 10.6** |
| Embodiment 7 | 17.5 | 15.5* | 14.7* | 13.0** | 12.3** |
| Embodiment 8 | 18.4 | 16.3* | 14.8* | 13.5** | 12.6** |
| Embodiment 9 | 18.4 | 16.5* | 13.6** | 12.2** | 11.6** |
| Comparative example 1 | 18.0 | 16.4 | 15.5* | 14.9** | 13.6** |
| Comparative example 2 | 18.2 | 17.6 | 16.5* | 16.0* | 15.2** |
* P < 0.05VS is before use, before * * P < 0.01VS use
As can be seen from Table 5, with use it is preceding compared with, acne score value is substantially reduced after opsonic water 3 days described in Examples 1 to 9
(P < 0.05) is significantly reduced when using 7,14 and 21 days, and statistically significant (P < 0.01).As can be seen from the table,
Compared with Example 1, the comprehensive scores after using 21 days of embodiment 4~6 are higher, illustrate that acne-removing composition A and B need
It is certain to match the lower better anti-acne effect of competence exertion；Compared with Example 1, the anti-acne effect of embodiment 7,8 and comparative example 1,2
It is slightly poor, illustrate anti-acne effect that acne-removing composition A, acne-removing composition B, Fructus psidii guajavae immaturus extract are used cooperatively more preferably, embodiment 9
Anti-acne effect be worse than embodiment 1, illustrate that niacinamide can play certain auxiliary anti-acne effect jointly.
Embodiment 13
Product effect assessment
One, trial target: anti-acne opsonic water prepared by Examples 1 to 3
Two, tested crowd
Gender number: 90 people, men and women is than being about 1:1
Age: between 12~30 years old
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Grouping: being divided into 3 groups, every group of 30 people, and average age 25 ± 2 years old.
Three, test method: respectively using anti-acne opsonic water prepared by Examples 1 to 3, observe and experience using effect.
Application method: it after subject cleans face, takes suitable anti-acne opsonic water to be uniformly applied to face, is massaged into absorption.Often
Day sooner or later respectively using primary, adhere to using one month, at least check weekly once to understand whether there is or not whole body and local adverse reaction,
And result is recorded in detail.
Test assessment result is shown in Table 6~8.
6 embodiment of table, 1 anti-acne opsonic water tries out (one month) feedback conclusive table
7 embodiment of table, 2 anti-acne opsonic water tries out (one month) feedback conclusive table
8 embodiment of table, 3 anti-acne opsonic water tries out (one month) feedback conclusive table
By table 6~8 it is found that the anti-acne opsonic water of the embodiment of the present invention 1~3 liking and approving by subject, tested
Person indicates that anti-acne opsonic water of the present invention is gentle, and can restrain pore, skin of releiving, and adjusts skin water and oil balance, deep
Layer is repaired, improves small pox skin.With the degree of recognition highest of 1 anti-acne opsonic water of embodiment in Examples 1 to 3.It is all tested simultaneously
There is allergic phenomena in non-someone in person, does not also occur the situations such as pruitus, shouting pain, redness.Therefore, anti-acne conditioning of the present invention
Water temperature and safety can be used for a long time.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of anti-acne opsonic water, which is characterized in that include acne-removing composition A；The acne-removing composition A is improved in the anti-acne
Weight percentage in water is 0.4~0.6%；The acne-removing composition A includes Radix Salviae Miltiorrhizae root extract, the extraction of cloves bud
Object, radix scutellariae root extract, Angelica roots, licorice root extract and Gotu Kola P.E.
2. anti-acne opsonic water as described in claim 1, which is characterized in that the parts by weight of each component in the acne-removing composition A are as follows:
10~20 parts of Radix Salviae Miltiorrhizae root extract, 2~4 parts of cloves alabastrum extract, 1~3 part of radix scutellariae root extract, Angelica roots 1~3
Part, 0.5~2 part of licorice root extract and 0.5~2 part of Gotu Kola P.E；Preferably, each component in the acne-removing composition A
Parts by weight are as follows: 15 parts of Radix Salviae Miltiorrhizae root extract, 3 parts of cloves alabastrum extract, 2 parts of radix scutellariae root extract, Angelica roots 2
Part, 1 part of licorice root extract and 1 part of Gotu Kola P.E.
3. anti-acne opsonic water as described in claim 1, which is characterized in that the opsonic water also includes acne-removing composition B；It is described to dispel
Weight percentage of the acne composition B in the anti-acne opsonic water is 0.4~0.6%；The acne-removing composition B includes white flower
HERBA HEDYOTIS DIFFUSAE extract, honeysuckle extract and fruitlet Chinese honey locust seed extract.
4. anti-acne opsonic water as claimed in claim 3, which is characterized in that the parts by weight of each component in the acne-removing composition B are as follows:
0.5~2 part of 2~4 parts of herba hedyotis diffusae extract, 2~4 parts of honeysuckle extract and fruitlet Chinese honey locust seed extract；Preferably, described
The parts by weight of each component in acne-removing composition B are as follows: 3 parts of herba hedyotis diffusae extract, 3 parts of honeysuckle extract and fruitlet Chinese honey locust seed mention
Take 1 part of object.
5. anti-acne opsonic water as described in claim 1, which is characterized in that the opsonic water also includes Fructus psidii guajavae immaturus extract 0.14
~0.26%.
6. anti-acne opsonic water as described in claim 1, which is characterized in that the opsonic water also includes skin-active ingredient；The skin-active
Ingredient includes niacinamide；Weight percentage of the niacinamide in the opsonic water is 1~2%.
7. anti-acne opsonic water as described in claim 1, which is characterized in that the opsonic water also includes moisturizer；The moisturizer
Include propylene glycol, glycerol, ethoxy urea and Sodium Hyaluronate.
8. anti-acne opsonic water as described in claim 1, which is characterized in that the opsonic water also includes preservative；In the conditioning
In water, the preservative includes methyl hydroxybenzoate, the weight percentage 0.1185 that weight percentage is 0.08~0.12%
The iodine propilolic alcohol butyl that~0.158% Bis(hydroxymethyl)imidazolidinyl urea and weight percentage is 0.0015~0.002%
Mephenesin Carbamate.
9. anti-acne opsonic water as claimed in claim 3, which is characterized in that the opsonic water includes the group of following weight percentage
Point: acne-removing composition A0.4~0.6%, acne-removing composition B 0.4~0.6%, Fructus psidii guajavae immaturus extract 0.14~0.26%, cigarette
Amide 1~2%, glycerol 3.2~4.8%, propylene glycol 1.8~2.8%, ethoxy urea 0.7~1.3%, Sodium Hyaluronate 0.014
~0.026%, Cremophor RH40 0.013~0.027%, methyl hydroxybenzoate 0.08~0.12%, bis- (methylol) imidazoles
Ureine 0.1185~0.158% and iodine propilolic alcohol butyl mephenesin Carbamate 0.0015~0.002%.
10. anti-acne opsonic water as claimed in claim 3, which is characterized in that the opsonic water includes following weight percentage
Component: acne-removing composition A0.5%, acne-removing composition B 0.5%, Fructus psidii guajavae immaturus extract 0.2%, niacinamide 1.5%, glycerol
4%, propylene glycol 3.21%, ethoxy urea 1%, Sodium Hyaluronate 0.02%, Cremophor RH40 0.02%, methyl hydroxybenzoate
0.1%, Bis(hydroxymethyl)imidazolidinyl urea 0.14% and iodine propilolic alcohol butyl mephenesin Carbamate 0.00175%.
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| CN201811207347.8A CN109260075B (en) | 2018-10-16 | 2018-10-16 | Acne-removing conditioning water |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811207347.8A CN109260075B (en) | 2018-10-16 | 2018-10-16 | Acne-removing conditioning water |
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| CN109260075B CN109260075B (en) | 2021-06-15 |
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