CN104994842B - 高剂量柠檬酸钾蜡基质缓释片剂 - Google Patents
高剂量柠檬酸钾蜡基质缓释片剂 Download PDFInfo
- Publication number
- CN104994842B CN104994842B CN201380051420.6A CN201380051420A CN104994842B CN 104994842 B CN104994842 B CN 104994842B CN 201380051420 A CN201380051420 A CN 201380051420A CN 104994842 B CN104994842 B CN 104994842B
- Authority
- CN
- China
- Prior art keywords
- potassium citrate
- tablet
- granulating
- solubility
- high dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Oil, Petroleum & Natural Gas (AREA)
Abstract
Description
Claims (3)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/PH2013/000007 WO2014133401A1 (en) | 2013-02-28 | 2013-02-28 | High dose extended-release potassium citrate wax matrix tablet |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104994842A CN104994842A (zh) | 2015-10-21 |
CN104994842B true CN104994842B (zh) | 2018-04-27 |
Family
ID=51428563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380051420.6A Active CN104994842B (zh) | 2013-02-28 | 2013-02-28 | 高剂量柠檬酸钾蜡基质缓释片剂 |
Country Status (10)
Country | Link |
---|---|
US (1) | US9295659B2 (zh) |
EP (1) | EP2961389B1 (zh) |
JP (1) | JP6164507B2 (zh) |
KR (1) | KR102077524B1 (zh) |
CN (1) | CN104994842B (zh) |
ES (1) | ES2640022T3 (zh) |
HK (1) | HK1210723A1 (zh) |
PH (1) | PH12015500469A1 (zh) |
SG (1) | SG11201502666XA (zh) |
WO (1) | WO2014133401A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020080451A1 (ja) * | 2018-10-17 | 2020-04-23 | 京都府公立大学法人 | 糖尿病腎症における腎線維化抑制剤 |
KR102274835B1 (ko) * | 2019-06-17 | 2021-07-08 | 주식회사 한국팜비오 | 포타슘 시트레이트 조성물을 포함하는 서방형 정제 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102240272A (zh) * | 2010-05-13 | 2011-11-16 | 丽珠医药集团股份有限公司 | 一种枸橼酸钾缓释片及其制备方法 |
CN102488670A (zh) * | 2011-12-22 | 2012-06-13 | 苏州东瑞制药有限公司 | 双重缓释枸橼酸钾缓释制剂的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4904478A (en) | 1983-08-11 | 1990-02-27 | Mission Pharmacal Company | Slow-release sodium fluoride tablet and method for treatment of osteoporosis |
US20080131504A1 (en) * | 2006-12-01 | 2008-06-05 | Mission Pharmacal Co. | Short Term Slow Release Drug Delivery System |
DE102009004829A1 (de) * | 2009-01-13 | 2010-07-22 | Gkn Sinter Metals Holding Gmbh | Mischung zur Verhinderung von Oberflächenflecken |
JP5551895B2 (ja) * | 2009-06-23 | 2014-07-16 | 旭化成せんい株式会社 | 布バネ材用織物 |
CN101791299A (zh) * | 2010-01-18 | 2010-08-04 | 南京泽恒医药技术开发有限公司 | 一种枸橼酸钾缓释片的制备方法 |
JP6150148B2 (ja) | 2012-09-27 | 2017-06-21 | ユナイテッド・ラボラトリーズ・インコーポレイテッド | 徐放性クエン酸カリウムワックスマトリックスタブレットの製造方法 |
-
2013
- 2013-02-28 ES ES13876681.1T patent/ES2640022T3/es active Active
- 2013-02-28 CN CN201380051420.6A patent/CN104994842B/zh active Active
- 2013-02-28 WO PCT/PH2013/000007 patent/WO2014133401A1/en active Application Filing
- 2013-02-28 US US14/431,374 patent/US9295659B2/en active Active
- 2013-02-28 KR KR1020157011291A patent/KR102077524B1/ko active IP Right Grant
- 2013-02-28 JP JP2015560135A patent/JP6164507B2/ja active Active
- 2013-02-28 EP EP13876681.1A patent/EP2961389B1/en active Active
- 2013-02-28 SG SG11201502666XA patent/SG11201502666XA/en unknown
-
2015
- 2015-03-04 PH PH12015500469A patent/PH12015500469A1/en unknown
- 2015-11-27 HK HK15111694.9A patent/HK1210723A1/zh unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102240272A (zh) * | 2010-05-13 | 2011-11-16 | 丽珠医药集团股份有限公司 | 一种枸橼酸钾缓释片及其制备方法 |
CN102488670A (zh) * | 2011-12-22 | 2012-06-13 | 苏州东瑞制药有限公司 | 双重缓释枸橼酸钾缓释制剂的制备方法 |
Non-Patent Citations (1)
Title |
---|
Photoimages and the release characteristics of lipophilic matrix tablets containing highly water-soluble potassium citrate with high drug loadings;Qing-Ri Cao et al;《International Journal of Pharmaceutics》;20070424;第339卷;19–24页 * |
Also Published As
Publication number | Publication date |
---|---|
EP2961389B1 (en) | 2017-08-23 |
KR102077524B1 (ko) | 2020-02-14 |
US20150272913A1 (en) | 2015-10-01 |
SG11201502666XA (en) | 2015-05-28 |
JP6164507B2 (ja) | 2017-07-19 |
EP2961389A4 (en) | 2016-07-06 |
WO2014133401A1 (en) | 2014-09-04 |
CN104994842A (zh) | 2015-10-21 |
KR20150122620A (ko) | 2015-11-02 |
EP2961389A1 (en) | 2016-01-06 |
JP2016510024A (ja) | 2016-04-04 |
PH12015500469B1 (en) | 2015-04-20 |
PH12015500469A1 (en) | 2015-04-20 |
ES2640022T3 (es) | 2017-10-31 |
HK1210723A1 (zh) | 2016-05-06 |
US9295659B2 (en) | 2016-03-29 |
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Effective date of registration: 20190404 Address after: Singapore Singapore Patentee after: Nobel Vickers science private Co., Ltd. Address before: Mandaluyong, Philippines Co-patentee before: Rita Josefina M.Santos Patentee before: Temperature Dare G Mendoza Co-patentee before: Kenny U enlightening |
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