CN104994842A - 高剂量柠檬酸钾蜡基质缓释片剂 - Google Patents
高剂量柠檬酸钾蜡基质缓释片剂 Download PDFInfo
- Publication number
- CN104994842A CN104994842A CN201380051420.6A CN201380051420A CN104994842A CN 104994842 A CN104994842 A CN 104994842A CN 201380051420 A CN201380051420 A CN 201380051420A CN 104994842 A CN104994842 A CN 104994842A
- Authority
- CN
- China
- Prior art keywords
- potassium citrate
- tablet
- granulating
- brazil wax
- dissolubility
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Description
Claims (10)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/PH2013/000007 WO2014133401A1 (en) | 2013-02-28 | 2013-02-28 | High dose extended-release potassium citrate wax matrix tablet |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104994842A true CN104994842A (zh) | 2015-10-21 |
CN104994842B CN104994842B (zh) | 2018-04-27 |
Family
ID=51428563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380051420.6A Active CN104994842B (zh) | 2013-02-28 | 2013-02-28 | 高剂量柠檬酸钾蜡基质缓释片剂 |
Country Status (10)
Country | Link |
---|---|
US (1) | US9295659B2 (zh) |
EP (1) | EP2961389B1 (zh) |
JP (1) | JP6164507B2 (zh) |
KR (1) | KR102077524B1 (zh) |
CN (1) | CN104994842B (zh) |
ES (1) | ES2640022T3 (zh) |
HK (1) | HK1210723A1 (zh) |
PH (1) | PH12015500469A1 (zh) |
SG (1) | SG11201502666XA (zh) |
WO (1) | WO2014133401A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20210378997A1 (en) * | 2018-10-17 | 2021-12-09 | Kyoto Prefectural Public University Corporation | Inhibitor of renal fibrosis in diabetic nephropathy |
KR102274835B1 (ko) * | 2019-06-17 | 2021-07-08 | 주식회사 한국팜비오 | 포타슘 시트레이트 조성물을 포함하는 서방형 정제 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4904478A (en) | 1983-08-11 | 1990-02-27 | Mission Pharmacal Company | Slow-release sodium fluoride tablet and method for treatment of osteoporosis |
US20080131504A1 (en) * | 2006-12-01 | 2008-06-05 | Mission Pharmacal Co. | Short Term Slow Release Drug Delivery System |
DE102009004829A1 (de) * | 2009-01-13 | 2010-07-22 | Gkn Sinter Metals Holding Gmbh | Mischung zur Verhinderung von Oberflächenflecken |
JP5551895B2 (ja) * | 2009-06-23 | 2014-07-16 | 旭化成せんい株式会社 | 布バネ材用織物 |
CN101791299A (zh) * | 2010-01-18 | 2010-08-04 | 南京泽恒医药技术开发有限公司 | 一种枸橼酸钾缓释片的制备方法 |
CN102240272B (zh) | 2010-05-13 | 2013-07-10 | 丽珠医药集团股份有限公司 | 一种枸橼酸钾缓释片及其制备方法 |
CN102488670B (zh) | 2011-12-22 | 2013-05-01 | 苏州东瑞制药有限公司 | 双重缓释枸橼酸钾缓释制剂的制备方法 |
US11033627B2 (en) | 2012-09-27 | 2021-06-15 | Novex Science Pte. Limited | Method for producing extended-release potassium citrate wax matrix tablet |
-
2013
- 2013-02-28 ES ES13876681.1T patent/ES2640022T3/es active Active
- 2013-02-28 WO PCT/PH2013/000007 patent/WO2014133401A1/en active Application Filing
- 2013-02-28 US US14/431,374 patent/US9295659B2/en active Active
- 2013-02-28 EP EP13876681.1A patent/EP2961389B1/en active Active
- 2013-02-28 KR KR1020157011291A patent/KR102077524B1/ko active IP Right Grant
- 2013-02-28 JP JP2015560135A patent/JP6164507B2/ja active Active
- 2013-02-28 CN CN201380051420.6A patent/CN104994842B/zh active Active
- 2013-02-28 SG SG11201502666XA patent/SG11201502666XA/en unknown
-
2015
- 2015-03-04 PH PH12015500469A patent/PH12015500469A1/en unknown
- 2015-11-27 HK HK15111694.9A patent/HK1210723A1/zh unknown
Non-Patent Citations (1)
Title |
---|
QING-RI CAO ET AL: "Photoimages and the release characteristics of lipophilic matrix tablets containing highly water-soluble potassium citrate with high drug loadings", 《INTERNATIONAL JOURNAL OF PHARMACEUTICS》 * |
Also Published As
Publication number | Publication date |
---|---|
HK1210723A1 (zh) | 2016-05-06 |
PH12015500469B1 (en) | 2015-04-20 |
EP2961389A1 (en) | 2016-01-06 |
KR20150122620A (ko) | 2015-11-02 |
EP2961389B1 (en) | 2017-08-23 |
EP2961389A4 (en) | 2016-07-06 |
JP6164507B2 (ja) | 2017-07-19 |
SG11201502666XA (en) | 2015-05-28 |
PH12015500469A1 (en) | 2015-04-20 |
KR102077524B1 (ko) | 2020-02-14 |
CN104994842B (zh) | 2018-04-27 |
US20150272913A1 (en) | 2015-10-01 |
JP2016510024A (ja) | 2016-04-04 |
US9295659B2 (en) | 2016-03-29 |
WO2014133401A1 (en) | 2014-09-04 |
ES2640022T3 (es) | 2017-10-31 |
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Effective date of registration: 20190404 Address after: Singapore Singapore Patentee after: Nobel Vickers science private Co., Ltd. Address before: Mandaluyong, Philippines Co-patentee before: Rita Josefina M.Santos Patentee before: Temperature Dare G Mendoza Co-patentee before: Kenny U enlightening |
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