CN104710518A - 新白蛋白结合组合物、方法及应用 - Google Patents

新白蛋白结合组合物、方法及应用 Download PDF

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Publication number
CN104710518A
CN104710518A CN201510071238.8A CN201510071238A CN104710518A CN 104710518 A CN104710518 A CN 104710518A CN 201510071238 A CN201510071238 A CN 201510071238A CN 104710518 A CN104710518 A CN 104710518A
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Prior art keywords
albumin bound
seq
polypeptide
albumin
bound polypeptide
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CN201510071238.8A
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English (en)
Chinese (zh)
Inventor
L·阿布拉姆森
A·荣森
J·多甘
P-A·尼格伦
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201510071238.8A 2007-07-31 2008-07-17 新白蛋白结合组合物、方法及应用 Pending CN104710518A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US96261807P 2007-07-31 2007-07-31
US60/962,618 2007-07-31
EP07113533.9 2007-07-31
EP07113533 2007-07-31

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880101168.4A Division CN101765608B (zh) 2007-07-31 2008-07-17 新白蛋白结合组合物、方法及应用

Publications (1)

Publication Number Publication Date
CN104710518A true CN104710518A (zh) 2015-06-17

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CN201510071238.8A Pending CN104710518A (zh) 2007-07-31 2008-07-17 新白蛋白结合组合物、方法及应用
CN200880101168.4A Active CN101765608B (zh) 2007-07-31 2008-07-17 新白蛋白结合组合物、方法及应用

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CN200880101168.4A Active CN101765608B (zh) 2007-07-31 2008-07-17 新白蛋白结合组合物、方法及应用

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US (2) US8937153B2 (enExample)
EP (2) EP2190863B1 (enExample)
JP (1) JP5718638B2 (enExample)
CN (2) CN104710518A (enExample)
AU (1) AU2008281913B2 (enExample)
CA (1) CA2694139C (enExample)
DE (1) DE08786222T1 (enExample)
DK (1) DK2190863T3 (enExample)
ES (1) ES2346178T3 (enExample)
HK (1) HK1211040A1 (enExample)
WO (1) WO2009016043A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
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CN115397516A (zh) * 2020-03-09 2022-11-25 霍伯生物技术公司 靶向her2的治疗剂
CN118666961A (zh) * 2024-08-23 2024-09-20 通化安睿特生物制药股份有限公司 人白蛋白特异结合多肽及其应用

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Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN115397516A (zh) * 2020-03-09 2022-11-25 霍伯生物技术公司 靶向her2的治疗剂
CN118666961A (zh) * 2024-08-23 2024-09-20 通化安睿特生物制药股份有限公司 人白蛋白特异结合多肽及其应用

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EP2546261A3 (en) 2013-08-14
ES2346178T1 (es) 2010-10-13
JP5718638B2 (ja) 2015-05-13
US20150158916A1 (en) 2015-06-11
CA2694139C (en) 2018-06-05
JP2010534486A (ja) 2010-11-11
WO2009016043A3 (en) 2009-06-04
DE08786222T1 (de) 2010-11-25
US10118949B2 (en) 2018-11-06
EP2546261A2 (en) 2013-01-16
US20100273979A1 (en) 2010-10-28
DK2190863T3 (en) 2015-11-30
AU2008281913A1 (en) 2009-02-05
US8937153B2 (en) 2015-01-20
ES2346178T3 (es) 2015-11-02
CA2694139A1 (en) 2009-02-05
WO2009016043A2 (en) 2009-02-05
EP2190863A2 (en) 2010-06-02
CN101765608B (zh) 2015-03-11
HK1211040A1 (en) 2016-05-13
AU2008281913B2 (en) 2013-11-07
EP2190863B1 (en) 2015-09-02
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