HK1218534A1 - 支架化肽文庫以及其製備和篩選方法 - Google Patents

支架化肽文庫以及其製備和篩選方法

Info

Publication number
HK1218534A1
HK1218534A1 HK16106500.2A HK16106500A HK1218534A1 HK 1218534 A1 HK1218534 A1 HK 1218534A1 HK 16106500 A HK16106500 A HK 16106500A HK 1218534 A1 HK1218534 A1 HK 1218534A1
Authority
HK
Hong Kong
Prior art keywords
screening
making
methods
same
peptidic libraries
Prior art date
Application number
HK16106500.2A
Other languages
English (en)
Inventor
馬魯蒂．阿帕拉帕提
薩契戴夫．
．西德胡
亞倫．科曼
Original Assignee
Governing Council Univ Toronto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Governing Council Univ Toronto filed Critical Governing Council Univ Toronto
Publication of HK1218534A1 publication Critical patent/HK1218534A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
HK16106500.2A 2013-03-14 2016-06-07 支架化肽文庫以及其製備和篩選方法 HK1218534A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361784077P 2013-03-14 2013-03-14
US201361804982P 2013-03-25 2013-03-25
PCT/IB2014/001088 WO2014140882A2 (en) 2013-03-14 2014-03-14 Scaffolded peptidic libraries and methods of making and screening the same

Publications (1)

Publication Number Publication Date
HK1218534A1 true HK1218534A1 (zh) 2017-02-24

Family

ID=51538210

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16106500.2A HK1218534A1 (zh) 2013-03-14 2016-06-07 支架化肽文庫以及其製備和篩選方法

Country Status (7)

Country Link
US (1) US10093921B2 (zh)
EP (1) EP2971290A4 (zh)
CN (1) CN105247118A (zh)
AU (1) AU2014229549B2 (zh)
CA (1) CA2902789A1 (zh)
HK (1) HK1218534A1 (zh)
WO (1) WO2014140882A2 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9200251B1 (en) 2011-03-31 2015-12-01 David Gordon Bermudes Bacterial methionine analogue and methionine synthesis inhibitor anticancer, antiinfective and coronary heart disease protective microcins and methods of treatment therewith
CN107798215B (zh) * 2017-11-15 2021-07-23 扬州大学 基于ppi网络层次结构预测功能模块及作用的方法
CN114174334A (zh) 2019-03-22 2022-03-11 反射制药有限公司 针对vegf的d-肽化合物
US20230203129A1 (en) * 2019-12-18 2023-06-29 Bracco Imaging S.P.A. Anti-her2 polypeptides derivatives as new diagnostic molecular probes
WO2021122729A1 (en) * 2019-12-18 2021-06-24 Bracco Imaging Spa Anti-her2 polypeptides derivatives as new diagnostic molecular probes
CN116621947B (zh) * 2023-07-18 2023-11-07 北京智源人工智能研究院 一种基于索烃骨架的拓扑蛋白质、制备方法及应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992020791A1 (en) 1990-07-10 1992-11-26 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
AU665025B2 (en) 1991-09-23 1995-12-14 Cambridge Antibody Technology Limited Production of chimeric antibodies - a combinatorial approach
ATE275198T1 (de) 1991-12-02 2004-09-15 Medical Res Council Herstellung von antikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken.
EP0656941B1 (en) 1992-03-24 2005-06-01 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
EP0647266B1 (en) 1992-06-05 1999-04-07 The Scripps Research Institute D-enzyme compositions and methods of their use
US5780221A (en) 1995-05-03 1998-07-14 Whitehead Institute For Biomedical Research Identification of enantiomeric ligands
US6184344B1 (en) 1995-05-04 2001-02-06 The Scripps Research Institute Synthesis of proteins by native chemical ligation
EP2154535A1 (en) 1998-12-10 2010-02-17 Bristol-Myers Squibb Company Protein scaffolds for antibody mimics and other binding proteins
US6663862B1 (en) 1999-06-04 2003-12-16 Duke University Reagents for detection and purification of antibody fragments
ES2346178T3 (es) 2007-07-31 2015-11-02 Affibody Ab Nuevas composiciones, procedimientos y usos de unión de la albúmina
EP2324048A2 (en) 2008-07-30 2011-05-25 Cosmix Therapeutics Llc Peptide therapeutics that bind vegf and methods of use thereof
ES2548030T3 (es) * 2009-06-01 2015-10-13 Medimmune, Llc Moléculas con semividas prolongadas y usos de las mismas
WO2012003484A2 (en) 2010-07-02 2012-01-05 Neurodynamics, LLC Catheter for use in revascularization procedures and method of using same
WO2012078313A2 (en) 2010-11-12 2012-06-14 Reflexion Pharmaceuticals, Inc. Gb1 peptidic libraries and compounds, and methods of screening the same
US9414816B2 (en) 2011-06-23 2016-08-16 Devicor Medical Products, Inc. Introducer for biopsy device
WO2013177398A2 (en) * 2012-05-25 2013-11-28 Janssen Biotech, Inc. Non-natural consensus albumin binding domains
PL2912054T3 (pl) * 2012-10-25 2017-11-30 Affibody Ab Polipeptyd wiążący albuminę

Also Published As

Publication number Publication date
WO2014140882A2 (en) 2014-09-18
EP2971290A2 (en) 2016-01-20
WO2014140882A3 (en) 2015-02-19
WO2014140882A8 (en) 2015-11-12
CN105247118A (zh) 2016-01-13
EP2971290A4 (en) 2017-03-01
AU2014229549B2 (en) 2018-11-01
CA2902789A1 (en) 2014-09-18
US10093921B2 (en) 2018-10-09
AU2014229549A1 (en) 2015-09-10
US20150376604A1 (en) 2015-12-31

Similar Documents

Publication Publication Date Title
HK1250481A1 (zh) 經過修飾的t細胞及其製備和使用方法
HK1249445A1 (zh) 抗分揀蛋白抗體和其使用方法
HK1252698A1 (zh) 抗siglec-9抗體及其使用方法
IL259495A (en) Antibodies and methods for using them
IL255801A (en) Liposomal nanoconstructs and methods of making and using the same
HK1252696A1 (zh) 抗siglec-7抗體及其使用方法
SG10201912150TA (en) Anti-trem2 antibodies and methods of use thereof
HK1256838A1 (zh) 模塊化多肽文庫以及其製備和使用方法
HK1255331A1 (zh) 抗pcsk9抗體及其應用
IL270793A (en) Anti-HTRA1 antibodies and methods of using them
HK1218534A1 (zh) 支架化肽文庫以及其製備和篩選方法
GB201519128D0 (en) Solid forms and methods of preparing the same
HK1250146A1 (zh) 抗前-bcr拮抗劑和方法
HK1243118A1 (zh) 新型支撑劑及其使用方法
SI3072560T1 (sl) Sistem trampolinov in postopki za njihovo izdelavo in uporabo
GB2558025B (en) Particulates and methods of making particulates
SG10202102552RA (en) Adsorbents and methods of making and using adsorbents
GB201517786D0 (en) Methods and materials
GB201518477D0 (en) Biomolecule separation and modification
IL247448A0 (en) Peptides and methods of use