AU2008281913B2 - New albumin binding compositions, methods and uses - Google Patents
New albumin binding compositions, methods and uses Download PDFInfo
- Publication number
- AU2008281913B2 AU2008281913B2 AU2008281913A AU2008281913A AU2008281913B2 AU 2008281913 B2 AU2008281913 B2 AU 2008281913B2 AU 2008281913 A AU2008281913 A AU 2008281913A AU 2008281913 A AU2008281913 A AU 2008281913A AU 2008281913 B2 AU2008281913 B2 AU 2008281913B2
- Authority
- AU
- Australia
- Prior art keywords
- seq
- albumin binding
- albumin
- amino acid
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96261807P | 2007-07-31 | 2007-07-31 | |
| US60/962,618 | 2007-07-31 | ||
| EP07113533.9 | 2007-07-31 | ||
| EP07113533 | 2007-07-31 | ||
| PCT/EP2008/059389 WO2009016043A2 (en) | 2007-07-31 | 2008-07-17 | New albumin binding compositions, methods and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008281913A1 AU2008281913A1 (en) | 2009-02-05 |
| AU2008281913B2 true AU2008281913B2 (en) | 2013-11-07 |
Family
ID=40057660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008281913A Active AU2008281913B2 (en) | 2007-07-31 | 2008-07-17 | New albumin binding compositions, methods and uses |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8937153B2 (enExample) |
| EP (2) | EP2190863B1 (enExample) |
| JP (1) | JP5718638B2 (enExample) |
| CN (2) | CN104710518A (enExample) |
| AU (1) | AU2008281913B2 (enExample) |
| CA (1) | CA2694139C (enExample) |
| DE (1) | DE08786222T1 (enExample) |
| DK (1) | DK2190863T3 (enExample) |
| ES (1) | ES2346178T3 (enExample) |
| HK (1) | HK1211040A1 (enExample) |
| WO (1) | WO2009016043A2 (enExample) |
Families Citing this family (82)
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| ES2346178T3 (es) * | 2007-07-31 | 2015-11-02 | Affibody Ab | Nuevas composiciones, procedimientos y usos de unión de la albúmina |
| US20120134984A1 (en) * | 2009-06-01 | 2012-05-31 | Olga Lubman | Molecules with extended half-lives and uses thereof |
| JP5951509B2 (ja) * | 2010-03-08 | 2016-07-13 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 免疫グロブリンGFc領域結合ポリペプチド |
| CA2793715A1 (en) * | 2010-04-30 | 2011-11-03 | Sanwa Kagaku Kenkyusho Co., Ltd. | Peptide for improving in vivo stability of physiologically active substance or the like and physiologically active substance with improved in vivo stability |
| KR101884654B1 (ko) | 2010-07-09 | 2018-08-02 | 애피바디 에이비 | 폴리펩타이드 |
| SG187682A1 (en) * | 2010-08-02 | 2013-03-28 | Macrogenics Inc | Covalent diabodies and uses thereof |
| CA2813087C (en) | 2010-09-28 | 2020-07-21 | Amylin Pharmaceuticals, Llc | Engineered polypeptides having enhanced duration of action |
| JP6121330B2 (ja) | 2010-09-28 | 2017-04-26 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続時間が増した改変ポリペプチド |
| US9284361B2 (en) | 2010-11-26 | 2016-03-15 | Molecular Partners Ag | Designed repeat proteins binding to serum albumin |
| CA2836873C (en) * | 2011-05-21 | 2019-10-22 | Macrogenics, Inc. | Deimmunized serum-binding domains and their use for extending serum half-life |
| CN103957926B (zh) * | 2011-07-08 | 2018-07-03 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| JP6006309B2 (ja) * | 2011-07-08 | 2016-10-12 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド |
| SMT201900189T1 (it) | 2012-02-20 | 2019-05-10 | Swedish Orphan Biovitrum Ab Publ | Polipeptidi che si legano al c5 del complemento umano |
| JP2020033372A (ja) * | 2012-03-28 | 2020-03-05 | アフィボディ・アーベー | 経口投与 |
| EP2844269A4 (en) * | 2012-03-28 | 2016-01-06 | Amylin Pharmaceuticals Llc | TRANSMUCOSAL ADMINISTRATION OF MANIPULATED POLYPEPTIDES |
| EP2830665A1 (en) | 2012-03-28 | 2015-02-04 | Affibody AB | Oral administration |
| WO2013177398A2 (en) | 2012-05-25 | 2013-11-28 | Janssen Biotech, Inc. | Non-natural consensus albumin binding domains |
| KR102123457B1 (ko) * | 2012-09-25 | 2020-06-16 | 애피바디 에이비 | 알부민 결합 폴리펩타이드 |
| CN104768976B (zh) | 2012-10-05 | 2020-09-22 | 阿菲博迪公司 | Her3结合多肽 |
| PL2912051T3 (pl) * | 2012-10-25 | 2018-08-31 | Affibody Ab | Sposób rozdzielania białek zawierających domenę wiążącą albuminę |
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| WO2014076179A1 (en) | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
| US9255262B2 (en) | 2013-03-06 | 2016-02-09 | Vision Global Holdings Ltd. | Albumin-binding arginine deminase and the use thereof |
| USRE48805E1 (en) | 2013-03-06 | 2021-11-02 | Vision Global Holdings Ltd. | Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein |
| CA2902789A1 (en) | 2013-03-14 | 2014-09-18 | The Governing Council Of The University Of Toronto | Scaffolded peptidic libraries and methods of making and screening the same |
| RU2015142437A (ru) | 2013-03-14 | 2017-04-27 | Дайити Санкио Ко., Лтд | Новые связывающие белки для pcsk9 |
| CA2902657C (en) | 2013-03-15 | 2022-05-10 | Affibody Ab | Fcrn binding polypeptides |
| HK1215681A1 (zh) | 2013-04-18 | 2016-09-09 | Armo Biosciences, Inc. | 使用白细胞介素-10治疗疾病和病症的方法 |
| ES2688206T3 (es) | 2013-06-17 | 2018-10-31 | Armo Biosciences, Inc. | Procedimiento de evaluación de la identidad y la estabilidad de proteínas |
| DK3038633T3 (da) | 2013-08-28 | 2021-01-11 | Ipc Res Llc | Stabile polypeptider der binder til human komplement c5 |
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| JP2024506070A (ja) | 2021-02-15 | 2024-02-08 | アフィボディ アクティエボラーグ | 新規her2結合ポリペプチド |
| KR20240139058A (ko) | 2022-02-08 | 2024-09-20 | 애피바디 에이비 | 흉선 기질 림포포이에틴에 결합하는 단백질 z 변이체 및 이의 의학적 용도 |
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-
2008
- 2008-07-17 ES ES08786222.3T patent/ES2346178T3/es active Active
- 2008-07-17 CN CN201510071238.8A patent/CN104710518A/zh active Pending
- 2008-07-17 JP JP2010518606A patent/JP5718638B2/ja active Active
- 2008-07-17 US US12/452,731 patent/US8937153B2/en active Active
- 2008-07-17 CA CA2694139A patent/CA2694139C/en active Active
- 2008-07-17 AU AU2008281913A patent/AU2008281913B2/en active Active
- 2008-07-17 CN CN200880101168.4A patent/CN101765608B/zh active Active
- 2008-07-17 DK DK08786222.3T patent/DK2190863T3/da active
- 2008-07-17 EP EP08786222.3A patent/EP2190863B1/en active Active
- 2008-07-17 EP EP12176805.5A patent/EP2546261A3/en not_active Withdrawn
- 2008-07-17 WO PCT/EP2008/059389 patent/WO2009016043A2/en not_active Ceased
- 2008-07-17 DE DE08786222T patent/DE08786222T1/de active Pending
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2014
- 2014-11-24 US US14/551,931 patent/US10118949B2/en active Active
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2015
- 2015-12-02 HK HK15111838.6A patent/HK1211040A1/xx unknown
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995027787A1 (fr) * | 1994-04-06 | 1995-10-19 | Pierre Fabre Medicament | Fragment peptidique de la proteine g du virus respiratoire syncytial, agent immunogene, composition pharmaceutique le contenant et procede de preparation |
| WO1996014416A1 (fr) * | 1994-11-07 | 1996-05-17 | Pierre Fabre Medicament | Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins |
| WO1999016873A1 (de) * | 1997-09-26 | 1999-04-08 | Arne Skerra | Anticaline |
| JP2003502022A (ja) * | 1999-05-14 | 2003-01-21 | アフィボディ・テクノロジー・スウェーデン・アーベー | 自己会合性生体分子構造物 |
| WO2003029463A2 (en) * | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| WO2003029471A1 (en) * | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of apolipoprotein d |
| WO2005075507A1 (en) * | 2004-02-09 | 2005-08-18 | Affibody Ab | Amyloid beta peptide binding polypeptide |
| WO2005097202A2 (en) * | 2004-04-06 | 2005-10-20 | Affibody Ab | Use of serum albumin binding peptides conjugates for the preparation of a medicament |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2546261A2 (en) | 2013-01-16 |
| EP2546261A3 (en) | 2013-08-14 |
| HK1211040A1 (en) | 2016-05-13 |
| WO2009016043A2 (en) | 2009-02-05 |
| CA2694139A1 (en) | 2009-02-05 |
| ES2346178T3 (es) | 2015-11-02 |
| CN104710518A (zh) | 2015-06-17 |
| EP2190863A2 (en) | 2010-06-02 |
| US20150158916A1 (en) | 2015-06-11 |
| US20100273979A1 (en) | 2010-10-28 |
| DK2190863T3 (en) | 2015-11-30 |
| CN101765608B (zh) | 2015-03-11 |
| CN101765608A (zh) | 2010-06-30 |
| EP2190863B1 (en) | 2015-09-02 |
| AU2008281913A1 (en) | 2009-02-05 |
| US10118949B2 (en) | 2018-11-06 |
| WO2009016043A3 (en) | 2009-06-04 |
| DE08786222T1 (de) | 2010-11-25 |
| JP2010534486A (ja) | 2010-11-11 |
| ES2346178T1 (es) | 2010-10-13 |
| US8937153B2 (en) | 2015-01-20 |
| CA2694139C (en) | 2018-06-05 |
| JP5718638B2 (ja) | 2015-05-13 |
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| FGA | Letters patent sealed or granted (standard patent) |