CN104471423B - 在组织微细管网络内的水的相对量的量化 - Google Patents

在组织微细管网络内的水的相对量的量化 Download PDF

Info

Publication number
CN104471423B
CN104471423B CN201380033778.6A CN201380033778A CN104471423B CN 104471423 B CN104471423 B CN 104471423B CN 201380033778 A CN201380033778 A CN 201380033778A CN 104471423 B CN104471423 B CN 104471423B
Authority
CN
China
Prior art keywords
diffusion
flow
pgse
data
velocity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201380033778.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN104471423A (zh
Inventor
丹尼尔·托普加德
萨摩·拉西克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Douglick
Landmwork Imaging Co ltd
Original Assignee
CR Development AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CR Development AB filed Critical CR Development AB
Publication of CN104471423A publication Critical patent/CN104471423A/zh
Application granted granted Critical
Publication of CN104471423B publication Critical patent/CN104471423B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0263—Measuring blood flow using NMR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/5635—Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56366—Perfusion imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56509—Correction of image distortions, e.g. due to magnetic field inhomogeneities due to motion, displacement or flow, e.g. gradient moment nulling
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/041—Controlled or regulated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/543—Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608—Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Signal Processing (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CN201380033778.6A 2012-06-29 2013-06-24 在组织微细管网络内的水的相对量的量化 Active CN104471423B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261665998P 2012-06-29 2012-06-29
SE1250736 2012-06-29
SE1250736-4 2012-06-29
US61/665,998 2012-06-29
PCT/SE2013/050755 WO2014003643A1 (en) 2012-06-29 2013-06-24 Quantification of the relative amount of water in the tissue microcapillary network

Publications (2)

Publication Number Publication Date
CN104471423A CN104471423A (zh) 2015-03-25
CN104471423B true CN104471423B (zh) 2017-03-29

Family

ID=49783621

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380033778.6A Active CN104471423B (zh) 2012-06-29 2013-06-24 在组织微细管网络内的水的相对量的量化

Country Status (10)

Country Link
US (2) US10031204B2 (enExample)
EP (1) EP2867690B1 (enExample)
JP (1) JP6328624B2 (enExample)
KR (1) KR102059408B1 (enExample)
CN (1) CN104471423B (enExample)
AU (1) AU2013281266B2 (enExample)
BR (1) BR112014032534B8 (enExample)
CA (1) CA2876852C (enExample)
IN (1) IN2014MN02502A (enExample)
WO (1) WO2014003643A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344015A (zh) * 2015-07-15 2017-01-25 四川大学华西医院 一种异常扩散程度加权的弥散磁共振成像方法
US11241163B2 (en) * 2017-06-08 2022-02-08 The Board Of Trustees Of The University Of Illinois Measuring blood vessel characteristics with MRI
US10684340B1 (en) * 2019-01-08 2020-06-16 Siemens Healthcare Gmbh Systems and methods for predicting errors and optimizing protocols in quantitative magnetic resonance imaging
CN109820506B (zh) * 2019-02-20 2023-07-07 王毅翔 基于磁共振弥散成像的组织血管密度指标检测方法及装置
WO2021201753A1 (en) * 2020-03-28 2021-10-07 Oezarslan Evren A magnetic resonance method, software product, and system for determining a diffusion propagator or related diffusion parameters for spin-labelled particles
CN111407278B (zh) * 2020-03-31 2020-12-29 浙江大学 利用流速补偿和非补偿的弥散磁共振测量胎盘血流的方法及装置
CN115421086B (zh) * 2022-09-02 2023-04-14 哈尔滨医科大学 活体心脏复杂组织学特征精准解析的超融合体素内不相干运动张量磁共振成像方法
CN117310581B (zh) * 2023-10-11 2024-05-10 安徽峻德医疗科技有限公司 一种核磁共振信号衰减拟合方法、系统、设备及存储介质

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5123312B1 (enExample) 1971-05-06 1976-07-15
JPH04357934A (ja) * 1991-06-05 1992-12-10 Toshiba Corp Ｍｒｉによるｉｖｉｍイメージング
JP3144840B2 (ja) 1991-07-31 2001-03-12 株式会社東芝 磁気共鳴イメージング装置
JP3146033B2 (ja) * 1991-11-05 2001-03-12 株式会社東芝 磁気共鳴イメージング装置
US8005530B2 (en) * 1995-04-12 2011-08-23 Prince Martin R Method and apparatus for imaging abdominal aorta and aortic aneurysms
JP3516373B2 (ja) 1996-09-04 2004-04-05 株式会社日立メディコ 磁気共鳴測定装置
JP4225620B2 (ja) * 1999-01-11 2009-02-18 株式会社東芝 Ｍｒｉ装置
WO2001038895A1 (en) * 1999-11-24 2001-05-31 Board Of Regents, The University Of Texas System Methods and systems for generating tractograms
US20040189297A1 (en) * 2002-12-13 2004-09-30 Michael Bock Imaging arrangement and process for locally-resolved imaging
JP4039980B2 (ja) * 2003-06-04 2008-01-30 マルホン工業株式会社 遊技機
JP3774713B2 (ja) * 2003-10-15 2006-05-17 株式会社東芝 コンタクトホールの形成方法
JP4357934B2 (ja) 2003-11-14 2009-11-04 アルパイン株式会社 ナビゲーション装置及び代替経路提示方法
BRPI0513896A (pt) 2004-07-30 2008-05-20 Ge Healthcare As método para a discriminação entre tecido saudável e de tumor
JP2005031099A (ja) * 2004-10-29 2005-02-03 Yokogawa Electric Corp 分光装置
DE102005008753B4 (de) 2005-02-25 2007-09-27 Siemens Ag Verfahren zur Darstellung von Fluss in einem Magnetresonanzbild
DE102005021067B4 (de) * 2005-05-06 2008-08-28 Siemens Ag Bildgebende Vorrichtung
US7411394B2 (en) * 2005-05-17 2008-08-12 Board Of Trustees Of Michigan State University Method for imaging diffusion anisotropy and diffusion gradient simultaneously
WO2007046172A1 (ja) 2005-10-20 2007-04-26 Niigata University 磁気共鳴画像処理方法および磁気共鳴画像処理装置
US8155729B1 (en) 2006-02-17 2012-04-10 General Electric Company Method and apparatus to compensate imaging data with simultaneously acquired motion data
US8053260B2 (en) 2006-11-17 2011-11-08 General Electric Company Large-area lighting systems and methods of making the same
JP4777372B2 (ja) 2008-02-08 2011-09-21 株式会社東芝 磁気共鳴イメージング装置
CN102077108B (zh) 2008-04-28 2015-02-25 康奈尔大学 分子mri中的磁敏度精确量化
US8497680B2 (en) * 2011-03-24 2013-07-30 University Hospital Of Basel Magnetic resonance method for quantification of molecular diffusion using double echo steady state sequences
US9075121B2 (en) * 2011-07-15 2015-07-07 Wisconsin Alumni Research Foundation System and method for rotating angle velocity encoding, phase contrast magnetic resonance imaging
WO2013025487A1 (en) * 2011-08-12 2013-02-21 The United States Of America, As Represented By The Secretary, Dpt Of Health And Human Services Spin echo sequences for diffusion weighted imaging of moving media

Also Published As

Publication number Publication date
JP6328624B2 (ja) 2018-05-23
IN2014MN02502A (enExample) 2015-07-17
BR112014032534B1 (pt) 2021-10-13
EP2867690A4 (en) 2017-01-25
BR112014032534B8 (pt) 2023-02-14
WO2014003643A1 (en) 2014-01-03
CA2876852C (en) 2020-12-22
AU2013281266B2 (en) 2017-04-13
JP2015521891A (ja) 2015-08-03
CA2876852A1 (en) 2014-01-03
EP2867690A1 (en) 2015-05-06
US10031204B2 (en) 2018-07-24
KR102059408B1 (ko) 2020-02-11
US20180224514A1 (en) 2018-08-09
EP2867690B1 (en) 2021-11-24
BR112014032534A2 (pt) 2017-06-27
US10788558B2 (en) 2020-09-29
AU2013281266A1 (en) 2015-01-22
CN104471423A (zh) 2015-03-25
KR20150036296A (ko) 2015-04-07
US20150168527A1 (en) 2015-06-18

Similar Documents

Publication Publication Date Title
CN104471423B (zh) 在组织微细管网络内的水的相对量的量化
Buonincontri et al. Multi-site repeatability and reproducibility of MR fingerprinting of the healthy brain at 1.5 and 3.0 T
Kundu et al. Multi-echo fMRI: A review of applications in fMRI denoising and analysis of BOLD signals
Kecskemeti et al. MPnRAGE: A technique to simultaneously acquire hundreds of differently contrasted MPRAGE images with applications to quantitative T1 mapping
Huang et al. The impact of gradient strength on in vivo diffusion MRI estimates of axon diameter
Gloor et al. Quantitative magnetization transfer imaging using balanced SSFP
Balu et al. Carotid plaque assessment using fast 3D isotropic resolution black‐blood MRI
Bammer et al. New methods in diffusion-weighted and diffusion tensor imaging
US8872515B2 (en) System and method for diffusion-modulated relaxation magnetic resonance imaging
US10215827B2 (en) Method to measure tissue texture using NMR spectroscopy to identify the chemical species of component textural elements in a targeted region of tissue
KR101359134B1 (ko) 도전율 및 자화율 복원 장치 및 방법과 이에 관한 기록매체
Kellman et al. Multicontrast delayed enhancement provides improved contrast between myocardial infarction and blood pool
Lommen et al. Probing the microscopic environment of 23Na ions in brain tissue by MRI: on the accuracy of different sampling schemes for the determination of rapid, biexponential decay at low signal‐to‐noise ratio
Leroi et al. Simultaneous proton density, T1, T2, and flip‐angle mapping of the brain at 7 T using multiparametric 3D SSFP imaging and parallel‐transmission universal pulses
Kerkelä et al. Comparative analysis of signal models for microscopic fractional anisotropy estimation using q-space trajectory encoding
Qin A simple approach for three‐dimensional mapping of baseline cerebrospinal fluid volume fraction
Maximov et al. Isotropically weighted intravoxel incoherent motion brain imaging at 7T
Stabinska et al. Investigation of diffusion time dependence of apparent diffusion coefficient and intravoxel incoherent motion parameters in the human kidney
Shen et al. Ultra‐high temporal resolution 4D angiography using arterial spin labeling with subspace reconstruction
JP7150056B2 (ja) 磁化の反転状態の評価を伴う動脈スピンラベリング法
WO2016186644A1 (en) System and method of obtaining spatially-encoded nmr parameters from arbitrarily-shaped compartments and linear algebraic modeling
Zhang et al. Respiratory motion-corrected T1 mapping of the abdomen
Burton et al. Spin Manipulations by Pulse Sequences
Cui et al. Time‐resolved MR fingerprinting for T2* signal extraction: MR fingerprinting meets echo planar time‐resolved imaging
Rispoli et al. Assessment of carotid flow using magnetic resonance imaging and computational fluid dynamics

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20221206

Address after: Lund, Sweden

Patentee after: Douglick

Address before: Lund, Sweden

Patentee before: CR DEVELOPMENT AB

Effective date of registration: 20221206

Address after: Okap, Sweden

Patentee after: Landmwork Imaging Co.,Ltd.

Address before: Lund, Sweden

Patentee before: Douglick