CA2876852C - Quantification of the relative amount of water in the tissue microcapillary network - Google Patents

Quantification of the relative amount of water in the tissue microcapillary network Download PDF

Info

Publication number
CA2876852C
CA2876852C CA2876852A CA2876852A CA2876852C CA 2876852 C CA2876852 C CA 2876852C CA 2876852 A CA2876852 A CA 2876852A CA 2876852 A CA2876852 A CA 2876852A CA 2876852 C CA2876852 C CA 2876852C
Authority
CA
Canada
Prior art keywords
flow
diffusion
compensated
data
pgse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2876852A
Other languages
English (en)
French (fr)
Other versions
CA2876852A1 (en
Inventor
Daniel Topgaard
Samo LASIC
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Random Walk Imaging AB
Original Assignee
CR Development AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CR Development AB filed Critical CR Development AB
Publication of CA2876852A1 publication Critical patent/CA2876852A1/en
Application granted granted Critical
Publication of CA2876852C publication Critical patent/CA2876852C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341Diffusion imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026Measuring blood flow
    • A61B5/0263Measuring blood flow using NMR
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/5635Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56366Perfusion imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56509Correction of image distortions, e.g. due to magnetic field inhomogeneities due to motion, displacement or flow, e.g. gradient moment nulling
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00Control; Monitoring or safety arrangements
    • F04C2270/04Force
    • F04C2270/041Controlled or regulated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/543Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Signal Processing (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CA2876852A 2012-06-29 2013-06-24 Quantification of the relative amount of water in the tissue microcapillary network Expired - Fee Related CA2876852C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261665998P 2012-06-29 2012-06-29
US61/665,998 2012-06-29
SE1250736-4 2012-06-29
SE1250736 2012-06-29
PCT/SE2013/050755 WO2014003643A1 (en) 2012-06-29 2013-06-24 Quantification of the relative amount of water in the tissue microcapillary network

Publications (2)

Publication Number Publication Date
CA2876852A1 CA2876852A1 (en) 2014-01-03
CA2876852C true CA2876852C (en) 2020-12-22

Family

ID=49783621

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2876852A Expired - Fee Related CA2876852C (en) 2012-06-29 2013-06-24 Quantification of the relative amount of water in the tissue microcapillary network

Country Status (10)

Country Link
US (2) US10031204B2 (enExample)
EP (1) EP2867690B1 (enExample)
JP (1) JP6328624B2 (enExample)
KR (1) KR102059408B1 (enExample)
CN (1) CN104471423B (enExample)
AU (1) AU2013281266B2 (enExample)
BR (1) BR112014032534B8 (enExample)
CA (1) CA2876852C (enExample)
IN (1) IN2014MN02502A (enExample)
WO (1) WO2014003643A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344015A (zh) * 2015-07-15 2017-01-25 四川大学华西医院 一种异常扩散程度加权的弥散磁共振成像方法
US11241163B2 (en) * 2017-06-08 2022-02-08 The Board Of Trustees Of The University Of Illinois Measuring blood vessel characteristics with MRI
US10684340B1 (en) * 2019-01-08 2020-06-16 Siemens Healthcare Gmbh Systems and methods for predicting errors and optimizing protocols in quantitative magnetic resonance imaging
CN109820506B (zh) * 2019-02-20 2023-07-07 王毅翔 基于磁共振弥散成像的组织血管密度指标检测方法及装置
WO2021201753A1 (en) * 2020-03-28 2021-10-07 Oezarslan Evren A magnetic resonance method, software product, and system for determining a diffusion propagator or related diffusion parameters for spin-labelled particles
CN111407278B (zh) * 2020-03-31 2020-12-29 浙江大学 利用流速补偿和非补偿的弥散磁共振测量胎盘血流的方法及装置
CN115421086B (zh) * 2022-09-02 2023-04-14 哈尔滨医科大学 活体心脏复杂组织学特征精准解析的超融合体素内不相干运动张量磁共振成像方法
CN117310581B (zh) * 2023-10-11 2024-05-10 安徽峻德医疗科技有限公司 一种核磁共振信号衰减拟合方法、系统、设备及存储介质

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5123312B1 (enExample) 1971-05-06 1976-07-15
JPH04357934A (ja) * 1991-06-05 1992-12-10 Toshiba Corp Mriによるivimイメージング
JP3144840B2 (ja) 1991-07-31 2001-03-12 株式会社東芝 磁気共鳴イメージング装置
JP3146033B2 (ja) * 1991-11-05 2001-03-12 株式会社東芝 磁気共鳴イメージング装置
US8005530B2 (en) * 1995-04-12 2011-08-23 Prince Martin R Method and apparatus for imaging abdominal aorta and aortic aneurysms
JP3516373B2 (ja) * 1996-09-04 2004-04-05 株式会社日立メディコ 磁気共鳴測定装置
JP4225620B2 (ja) * 1999-01-11 2009-02-18 株式会社東芝 Mri装置
WO2001038895A1 (en) 1999-11-24 2001-05-31 Board Of Regents, The University Of Texas System Methods and systems for generating tractograms
US20040189297A1 (en) * 2002-12-13 2004-09-30 Michael Bock Imaging arrangement and process for locally-resolved imaging
JP4039980B2 (ja) * 2003-06-04 2008-01-30 マルホン工業株式会社 遊技機
JP3774713B2 (ja) * 2003-10-15 2006-05-17 株式会社東芝 コンタクトホールの形成方法
JP4357934B2 (ja) 2003-11-14 2009-11-04 アルパイン株式会社 ナビゲーション装置及び代替経路提示方法
BRPI0513896A (pt) 2004-07-30 2008-05-20 Ge Healthcare As método para a discriminação entre tecido saudável e de tumor
JP2005031099A (ja) * 2004-10-29 2005-02-03 Yokogawa Electric Corp 分光装置
DE102005008753B4 (de) 2005-02-25 2007-09-27 Siemens Ag Verfahren zur Darstellung von Fluss in einem Magnetresonanzbild
DE102005021067B4 (de) * 2005-05-06 2008-08-28 Siemens Ag Bildgebende Vorrichtung
US7411394B2 (en) 2005-05-17 2008-08-12 Board Of Trustees Of Michigan State University Method for imaging diffusion anisotropy and diffusion gradient simultaneously
JP4961566B2 (ja) * 2005-10-20 2012-06-27 国立大学法人 新潟大学 磁気共鳴画像処理方法および磁気共鳴画像処理装置
US8155729B1 (en) * 2006-02-17 2012-04-10 General Electric Company Method and apparatus to compensate imaging data with simultaneously acquired motion data
US8053260B2 (en) 2006-11-17 2011-11-08 General Electric Company Large-area lighting systems and methods of making the same
JP4777372B2 (ja) * 2008-02-08 2011-09-21 株式会社東芝 磁気共鳴イメージング装置
CN105182263A (zh) 2008-04-28 2015-12-23 康奈尔大学 分子mri中的磁敏度精确量化
US8497680B2 (en) * 2011-03-24 2013-07-30 University Hospital Of Basel Magnetic resonance method for quantification of molecular diffusion using double echo steady state sequences
US9075121B2 (en) * 2011-07-15 2015-07-07 Wisconsin Alumni Research Foundation System and method for rotating angle velocity encoding, phase contrast magnetic resonance imaging
WO2013025487A1 (en) * 2011-08-12 2013-02-21 The United States Of America, As Represented By The Secretary, Dpt Of Health And Human Services Spin echo sequences for diffusion weighted imaging of moving media

Also Published As

Publication number Publication date
WO2014003643A1 (en) 2014-01-03
KR102059408B1 (ko) 2020-02-11
BR112014032534A2 (pt) 2017-06-27
AU2013281266B2 (en) 2017-04-13
AU2013281266A1 (en) 2015-01-22
BR112014032534B8 (pt) 2023-02-14
CN104471423B (zh) 2017-03-29
CN104471423A (zh) 2015-03-25
JP2015521891A (ja) 2015-08-03
US20180224514A1 (en) 2018-08-09
EP2867690A1 (en) 2015-05-06
KR20150036296A (ko) 2015-04-07
EP2867690B1 (en) 2021-11-24
IN2014MN02502A (enExample) 2015-07-17
EP2867690A4 (en) 2017-01-25
US20150168527A1 (en) 2015-06-18
CA2876852A1 (en) 2014-01-03
US10031204B2 (en) 2018-07-24
US10788558B2 (en) 2020-09-29
JP6328624B2 (ja) 2018-05-23
BR112014032534B1 (pt) 2021-10-13

Similar Documents

Publication Publication Date Title
CA2876852C (en) Quantification of the relative amount of water in the tissue microcapillary network
Ades-Aron et al. Evaluation of the accuracy and precision of the diffusion parameter EStImation with Gibbs and NoisE removal pipeline
Mädler et al. Is diffusion anisotropy an accurate monitor of myelination?: Correlation of multicomponent T2 relaxation and diffusion tensor anisotropy in human brain
Avram et al. Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure
McNab et al. Surface based analysis of diffusion orientation for identifying architectonic domains in the in vivo human cortex
Huang et al. The impact of gradient strength on in vivo diffusion MRI estimates of axon diameter
Alexander et al. Characterization of cerebral white matter properties using quantitative magnetic resonance imaging stains
Bosma et al. Assessment of data acquisition parameters, and analysis techniques for noise reduction in spinal cord fMRI data
Bammer et al. New methods in diffusion-weighted and diffusion tensor imaging
Heule et al. Rapid estimation of cartilage T2 with reduced T1 sensitivity using double echo steady state imaging
Jeong et al. High‐resolution DTI of a localized volume using 3D s ingle‐s hot diffusion‐weighted ST imulated e cho‐p lanar i maging (3D ss‐DWSTEPI)
van Gelderen et al. Effect of motion, cortical orientation and spatial resolution on quantitative imaging of cortical R2* and magnetic susceptibility at 0.3 mm in-plane resolution at 7 T
Tsougos Advanced MR neuroimaging: from theory to clinical practice
Lundell et al. Cerebellar imaging with diffusion magnetic resonance imaging: approaches, challenges, and potential
Freidlin et al. A spin echo sequence with a single-sided bipolar diffusion gradient pulse to obtain snapshot diffusion weighted images in moving media
JP7150056B2 (ja) 磁化の反転状態の評価を伴う動脈スピンラベリング法
Ghosh et al. Advanced Diffusion Models¹
Sid et al. Analytical performance bounds for multi-tensor diffusion-MRI
Ben-Eliezer Advances in signal processing for relaxometry
Liu et al. A practical approach to in vivo high-resolution diffusion tensor imaging of rhesus monkeys on a 3-T human scanner
Çavuşoğlu Arterial spin labeling MRI using spiral acquisitions and concurrent field monitoring
Bougias et al. Theory of diffusion tensor imaging and fiber tractography analysis
Skare Optimisation in strategies in diffusion tensor MR imaging
Goryawala et al. A Path to Establishing MRSI as a Clinical Standard Imaging
Ellingson et al. High order diffusion tensor imaging in human glioblastoma

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180620

MKLA Lapsed

Effective date: 20220627