KR102059408B1 - 조직 마이크로모세관 네트워크에서 물의 상대적인 양의 정량화 - Google Patents

조직 마이크로모세관 네트워크에서 물의 상대적인 양의 정량화 Download PDF

Info

Publication number
KR102059408B1
KR102059408B1 KR1020157002610A KR20157002610A KR102059408B1 KR 102059408 B1 KR102059408 B1 KR 102059408B1 KR 1020157002610 A KR1020157002610 A KR 1020157002610A KR 20157002610 A KR20157002610 A KR 20157002610A KR 102059408 B1 KR102059408 B1 KR 102059408B1
Authority
KR
South Korea
Prior art keywords
flow
data
pulse
diffusion
compensated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020157002610A
Other languages
English (en)
Korean (ko)
Other versions
KR20150036296A (ko
Inventor
다니엘 토프가르드
사모 라시크
Original Assignee
씨알 디벨로프먼트 에이비
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 씨알 디벨로프먼트 에이비 filed Critical 씨알 디벨로프먼트 에이비
Publication of KR20150036296A publication Critical patent/KR20150036296A/ko
Application granted granted Critical
Publication of KR102059408B1 publication Critical patent/KR102059408B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0263—Measuring blood flow using NMR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/5635—Angiography, e.g. contrast-enhanced angiography [CE-MRA] or time-of-flight angiography [TOF-MRA]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56366—Perfusion imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56509—Correction of image distortions, e.g. due to magnetic field inhomogeneities due to motion, displacement or flow, e.g. gradient moment nulling
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/041—Controlled or regulated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/543—Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608—Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Signal Processing (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
KR1020157002610A 2012-06-29 2013-06-24 조직 마이크로모세관 네트워크에서 물의 상대적인 양의 정량화 Active KR102059408B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261665998P 2012-06-29 2012-06-29
SE1250736 2012-06-29
US61/665,998 2012-06-29
SE1250736-4 2012-06-29
PCT/SE2013/050755 WO2014003643A1 (en) 2012-06-29 2013-06-24 Quantification of the relative amount of water in the tissue microcapillary network

Publications (2)

Publication Number Publication Date
KR20150036296A KR20150036296A (ko) 2015-04-07
KR102059408B1 true KR102059408B1 (ko) 2020-02-11

Family

ID=49783621

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157002610A Active KR102059408B1 (ko) 2012-06-29 2013-06-24 조직 마이크로모세관 네트워크에서 물의 상대적인 양의 정량화

Country Status (10)

Country Link
US (2) US10031204B2 (enExample)
EP (1) EP2867690B1 (enExample)
JP (1) JP6328624B2 (enExample)
KR (1) KR102059408B1 (enExample)
CN (1) CN104471423B (enExample)
AU (1) AU2013281266B2 (enExample)
BR (1) BR112014032534B8 (enExample)
CA (1) CA2876852C (enExample)
IN (1) IN2014MN02502A (enExample)
WO (1) WO2014003643A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106344015A (zh) * 2015-07-15 2017-01-25 四川大学华西医院 一种异常扩散程度加权的弥散磁共振成像方法
US11241163B2 (en) * 2017-06-08 2022-02-08 The Board Of Trustees Of The University Of Illinois Measuring blood vessel characteristics with MRI
US10684340B1 (en) * 2019-01-08 2020-06-16 Siemens Healthcare Gmbh Systems and methods for predicting errors and optimizing protocols in quantitative magnetic resonance imaging
CN109820506B (zh) * 2019-02-20 2023-07-07 王毅翔 基于磁共振弥散成像的组织血管密度指标检测方法及装置
WO2021201753A1 (en) * 2020-03-28 2021-10-07 Oezarslan Evren A magnetic resonance method, software product, and system for determining a diffusion propagator or related diffusion parameters for spin-labelled particles
CN111407278B (zh) * 2020-03-31 2020-12-29 浙江大学 利用流速补偿和非补偿的弥散磁共振测量胎盘血流的方法及装置
CN115421086B (zh) * 2022-09-02 2023-04-14 哈尔滨医科大学 活体心脏复杂组织学特征精准解析的超融合体素内不相干运动张量磁共振成像方法
CN117310581B (zh) * 2023-10-11 2024-05-10 安徽峻德医疗科技有限公司 一种核磁共振信号衰减拟合方法、系统、设备及存储介质

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004357934A (ja) 2003-06-04 2004-12-24 Maruhon Ind Co Ltd 遊技機
JP2005031099A (ja) 2004-10-29 2005-02-03 Yokogawa Electric Corp 分光装置
JP2005123312A (ja) 2003-10-15 2005-05-12 Toshiba Corp コンタクトホールの形成方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5123312B1 (enExample) 1971-05-06 1976-07-15
JPH04357934A (ja) * 1991-06-05 1992-12-10 Toshiba Corp Ｍｒｉによるｉｖｉｍイメージング
JP3144840B2 (ja) * 1991-07-31 2001-03-12 株式会社東芝 磁気共鳴イメージング装置
JP3146033B2 (ja) * 1991-11-05 2001-03-12 株式会社東芝 磁気共鳴イメージング装置
US8005530B2 (en) 1995-04-12 2011-08-23 Prince Martin R Method and apparatus for imaging abdominal aorta and aortic aneurysms
JP3516373B2 (ja) * 1996-09-04 2004-04-05 株式会社日立メディコ 磁気共鳴測定装置
JP4225620B2 (ja) 1999-01-11 2009-02-18 株式会社東芝 Ｍｒｉ装置
WO2001038895A1 (en) * 1999-11-24 2001-05-31 Board Of Regents, The University Of Texas System Methods and systems for generating tractograms
US20040189297A1 (en) * 2002-12-13 2004-09-30 Michael Bock Imaging arrangement and process for locally-resolved imaging
JP4357934B2 (ja) 2003-11-14 2009-11-04 アルパイン株式会社 ナビゲーション装置及び代替経路提示方法
CN101031811A (zh) * 2004-07-30 2007-09-05 通用电气医疗集团股份有限公司 肿瘤成像方法
DE102005008753B4 (de) * 2005-02-25 2007-09-27 Siemens Ag Verfahren zur Darstellung von Fluss in einem Magnetresonanzbild
DE102005021067B4 (de) * 2005-05-06 2008-08-28 Siemens Ag Bildgebende Vorrichtung
US7411394B2 (en) * 2005-05-17 2008-08-12 Board Of Trustees Of Michigan State University Method for imaging diffusion anisotropy and diffusion gradient simultaneously
WO2007046172A1 (ja) * 2005-10-20 2007-04-26 Niigata University 磁気共鳴画像処理方法および磁気共鳴画像処理装置
US8155729B1 (en) * 2006-02-17 2012-04-10 General Electric Company Method and apparatus to compensate imaging data with simultaneously acquired motion data
US8053260B2 (en) 2006-11-17 2011-11-08 General Electric Company Large-area lighting systems and methods of making the same
JP4777372B2 (ja) * 2008-02-08 2011-09-21 株式会社東芝 磁気共鳴イメージング装置
CN102077108B (zh) 2008-04-28 2015-02-25 康奈尔大学 分子mri中的磁敏度精确量化
US8497680B2 (en) 2011-03-24 2013-07-30 University Hospital Of Basel Magnetic resonance method for quantification of molecular diffusion using double echo steady state sequences
US9075121B2 (en) 2011-07-15 2015-07-07 Wisconsin Alumni Research Foundation System and method for rotating angle velocity encoding, phase contrast magnetic resonance imaging
WO2013025487A1 (en) * 2011-08-12 2013-02-21 The United States Of America, As Represented By The Secretary, Dpt Of Health And Human Services Spin echo sequences for diffusion weighted imaging of moving media

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004357934A (ja) 2003-06-04 2004-12-24 Maruhon Ind Co Ltd 遊技機
JP2005123312A (ja) 2003-10-15 2005-05-12 Toshiba Corp コンタクトホールの形成方法
JP2005031099A (ja) 2004-10-29 2005-02-03 Yokogawa Electric Corp 分光装置

Also Published As

Publication number Publication date
US20150168527A1 (en) 2015-06-18
CN104471423B (zh) 2017-03-29
BR112014032534B1 (pt) 2021-10-13
US20180224514A1 (en) 2018-08-09
EP2867690A1 (en) 2015-05-06
AU2013281266B2 (en) 2017-04-13
US10031204B2 (en) 2018-07-24
AU2013281266A1 (en) 2015-01-22
BR112014032534B8 (pt) 2023-02-14
JP6328624B2 (ja) 2018-05-23
KR20150036296A (ko) 2015-04-07
CA2876852A1 (en) 2014-01-03
EP2867690A4 (en) 2017-01-25
WO2014003643A1 (en) 2014-01-03
IN2014MN02502A (enExample) 2015-07-17
CA2876852C (en) 2020-12-22
EP2867690B1 (en) 2021-11-24
BR112014032534A2 (pt) 2017-06-27
JP2015521891A (ja) 2015-08-03
CN104471423A (zh) 2015-03-25
US10788558B2 (en) 2020-09-29

Similar Documents

Publication Publication Date Title
KR102059408B1 (ko) 조직 마이크로모세관 네트워크에서 물의 상대적인 양의 정량화
Kundu et al. Multi-echo fMRI: A review of applications in fMRI denoising and analysis of BOLD signals
Huang et al. The impact of gradient strength on in vivo diffusion MRI estimates of axon diameter
Alexander et al. Characterization of cerebral white matter properties using quantitative magnetic resonance imaging stains
Bammer et al. New methods in diffusion-weighted and diffusion tensor imaging
Bosma et al. Assessment of data acquisition parameters, and analysis techniques for noise reduction in spinal cord fMRI data
Horie et al. Magnetic resonance imaging technique for visualization of irregular cerebrospinal fluid motion in the ventricular system and subarachnoid space
US10215827B2 (en) Method to measure tissue texture using NMR spectroscopy to identify the chemical species of component textural elements in a targeted region of tissue
EP3648662B1 (en) A method to measure tissue texture using nmr spectroscopy to identify chemical species of component textural elements in a targeted region of tissue
WO2007104049A2 (en) Complex amplitude modulation in blood flow and perfusion measurement
Kan et al. Quantitative susceptibility mapping using principles of echo shifting with a train of observations sequence on 1.5 T MRI
Kerkelä et al. Comparative analysis of signal models for microscopic fractional anisotropy estimation using q-space trajectory encoding
Mohindra et al. Magnetic resonance sequences: Practical neurological applications
JP7150056B2 (ja) 磁化の反転状態の評価を伴う動脈スピンラベリング法
Falcão et al. Combined free-running four-dimensional anatomical and flow magnetic resonance imaging with native contrast using Synchronization of Neighboring Acquisitions by Physiological Signals
US20120268128A1 (en) Method for Principal Frequency Magnetic Resonance Elastography Inversion
Ghosh et al. Advanced Diffusion Models¹
Kim et al. Time-of-flight angiography
Çavuşoğlu Arterial spin labeling MRI using spiral acquisitions and concurrent field monitoring
Skare Optimisation in strategies in diffusion tensor MR imaging
Zhang et al. Respiratory motion-corrected T1 mapping of the abdomen
Goryawala et al. A Path to Establishing MRSI as a Clinical Standard Imaging
Zuo et al. Validation of V-SS-PARSE for single-shot flow measurement
Rispoli et al. Assessment of carotid flow using magnetic resonance imaging and computational fluid dynamics
Dietrich Techniques for diffusion and perfusion assessment in bone-marrow MRI

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R11-asn-PN2301

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R14-asn-PN2301

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R11-asn-PN2301

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R14-asn-PN2301

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 7