CN104363913B - Cdk8/cdk19选择性抑制剂及其在癌症的抗转移和化学预防方法中的用途 - Google Patents

Cdk8/cdk19选择性抑制剂及其在癌症的抗转移和化学预防方法中的用途 Download PDF

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CN104363913B
CN104363913B CN201380017703.9A CN201380017703A CN104363913B CN 104363913 B CN104363913 B CN 104363913B CN 201380017703 A CN201380017703 A CN 201380017703A CN 104363913 B CN104363913 B CN 104363913B
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cdk8
small molecule
cancer
medicament
tumor
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CN104363913A (zh
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I.B.罗宾逊
D.C.波尔特
M.P.温特兰德
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Senex Biotechnology Inc
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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CN201380017703.9A 2012-02-02 2013-02-01 Cdk8/cdk19选择性抑制剂及其在癌症的抗转移和化学预防方法中的用途 Expired - Fee Related CN104363913B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261594023P 2012-02-02 2012-02-02
US61/594,023 2012-02-02
US61/594023 2012-02-02
US201261673419P 2012-07-19 2012-07-19
US61/673419 2012-07-19
US61/673,419 2012-07-19
PCT/US2013/024515 WO2013116786A1 (en) 2012-02-02 2013-02-01 Cdk8/cdk19 selective inhibitors and their use in anti-metastatic and chemopreventative methods for cancer

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CN104363913A CN104363913A (zh) 2015-02-18
CN104363913B true CN104363913B (zh) 2018-08-21

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US (2) US9321737B2 (https=)
EP (2) EP2809324B1 (https=)
JP (1) JP6193268B2 (https=)
KR (1) KR20150023223A (https=)
CN (1) CN104363913B (https=)
AU (1) AU2013214783B2 (https=)
BR (1) BR112014019052A8 (https=)
CL (1) CL2014002062A1 (https=)
CO (1) CO7151516A2 (https=)
EA (2) EA028595B1 (https=)
GE (2) GEP20186818B (https=)
MY (1) MY165446A (https=)
PH (1) PH12014501862A1 (https=)
SG (1) SG11201404596UA (https=)
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