CN104114562A - 形成4-氯-2-氟-3-取代的苯基硼酸频哪醇酯的方法及其使用方法 - Google Patents
形成4-氯-2-氟-3-取代的苯基硼酸频哪醇酯的方法及其使用方法 Download PDFInfo
- Publication number
- CN104114562A CN104114562A CN201280069312.7A CN201280069312A CN104114562A CN 104114562 A CN104114562 A CN 104114562A CN 201280069312 A CN201280069312 A CN 201280069312A CN 104114562 A CN104114562 A CN 104114562A
- Authority
- CN
- China
- Prior art keywords
- chloro
- fluoro
- phenyl
- substituted
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
- C07D213/807—Processes of preparation by oxidation of pyridines or condensed pyridines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/02—Lithium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161582173P | 2011-12-30 | 2011-12-30 | |
| US61/582,173 | 2011-12-30 | ||
| PCT/US2012/070967 WO2013101665A1 (en) | 2011-12-30 | 2012-12-20 | Methods of forming 4-chloro-2-fluoro-3-substituted-phenylboronic acid pinacol esters and methods of using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104114562A true CN104114562A (zh) | 2014-10-22 |
Family
ID=48695350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280069312.7A Pending CN104114562A (zh) | 2011-12-30 | 2012-12-20 | 形成4-氯-2-氟-3-取代的苯基硼酸频哪醇酯的方法及其使用方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8912339B2 (https=) |
| EP (1) | EP2797933B1 (https=) |
| JP (2) | JP6290788B2 (https=) |
| KR (1) | KR102062343B1 (https=) |
| CN (1) | CN104114562A (https=) |
| AR (1) | AR089539A1 (https=) |
| AU (1) | AU2012362698B2 (https=) |
| BR (1) | BR112014016048B8 (https=) |
| CA (1) | CA2861631C (https=) |
| CO (1) | CO7020930A2 (https=) |
| IL (1) | IL233413A (https=) |
| IN (1) | IN2014DN05647A (https=) |
| MX (1) | MX341834B (https=) |
| NZ (1) | NZ627041A (https=) |
| PL (1) | PL2797933T3 (https=) |
| RU (1) | RU2625800C2 (https=) |
| WO (1) | WO2013101665A1 (https=) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108273550A (zh) * | 2018-04-16 | 2018-07-13 | 苏州大学张家港工业技术研究院 | 对甲基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108373480A (zh) * | 2018-04-16 | 2018-08-07 | 苏州大学 | 利用对甲基苯胺基锂制备硼酸酯的方法 |
| CN108404984A (zh) * | 2018-04-16 | 2018-08-17 | 苏州大学 | 正丁基锂在催化醛和硼烷硼氢化反应中的应用 |
| CN108409772A (zh) * | 2018-04-16 | 2018-08-17 | 南通纺织丝绸产业技术研究院 | 基于醛制备硼酸酯的方法 |
| CN108558925A (zh) * | 2018-04-16 | 2018-09-21 | 南通纺织丝绸产业技术研究院 | 2,6-二异丙基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN116715689A (zh) * | 2023-06-09 | 2023-09-08 | 珠海市海瑞德生物科技有限公司 | 氟比洛芬及其中间体的合成方法 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2797933T3 (pl) * | 2011-12-30 | 2018-01-31 | Dow Agrosciences Llc | Sposoby wytwarzania estrów pinakolowych kwasu 4-chloro-2-fluoro-3-podstawionego-fenyloboronowego oraz sposoby ich stosowania |
| RU2616621C2 (ru) * | 2011-12-30 | 2017-04-18 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы получения метил 4-амино-3-хлор-6-(4-хлор-2-фтор-3-метоксифенил)пиридин-2-карбоксилата |
| BR102014021960A2 (pt) | 2013-09-05 | 2015-09-15 | Univ Michigan State | métodos para a produção de arenos borilados |
| TW201625354A (zh) | 2014-06-16 | 2016-07-16 | 陶氏農業科學公司 | 用於製備氧硼基化芳烴之方法 |
| BR112017019207A2 (pt) * | 2015-05-22 | 2018-04-24 | Dow Agrosciences Llc | recuperação e/ou reutilização de catalisador de paládio após acoplamento de suzuki |
| CN108329339A (zh) * | 2018-04-16 | 2018-07-27 | 苏州大学张家港工业技术研究院 | 2,6-二甲基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108654692A (zh) * | 2018-04-16 | 2018-10-16 | 苏州大学 | 正丁基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108503660A (zh) * | 2018-04-16 | 2018-09-07 | 苏州大学 | 苯胺基锂在催化醛和硼烷硼氢化反应中的应用 |
| CN108383863A (zh) * | 2018-04-16 | 2018-08-10 | 苏州大学 | 2,6-二异丙基苯胺基锂在制备硼酸酯中的应用 |
| CN108503659A (zh) * | 2018-04-16 | 2018-09-07 | 苏州大学 | 利用2,6-二异丙基苯胺基锂制备硼酸酯的方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7314849B2 (en) * | 2006-01-13 | 2008-01-01 | Dow Agrosciences Llc | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides |
| CN101970446A (zh) * | 2008-01-11 | 2011-02-09 | 陶氏益农公司 | 对1-氟-2-取代的-3-氯苯选择性脱质子化和官能化的方法 |
| EP2181098B1 (en) * | 2007-08-30 | 2011-03-02 | Dow AgroSciences LLC | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides |
| US7915200B2 (en) * | 2007-08-13 | 2011-03-29 | Dow Agrosciences Llc | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides |
| EP2332914A1 (en) * | 2007-10-02 | 2011-06-15 | Dow AgroSciences LLC | Substituted 4-amino-picolinic acids and their use as herbicides |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0986541A4 (en) * | 1997-04-09 | 2002-08-14 | Commw Scient Ind Res Org | METHOD FOR COVALENT BINDING ORGANIC COMPOUNDS USING DIBORANE DERIVATIVES |
| EA200702614A1 (ru) * | 2005-05-25 | 2008-04-28 | Майкробиа, Инк. | Способы получения 4-(бифенилил)азетидин-2-оналкилфосфиновых кислот |
| US7964758B2 (en) * | 2006-02-13 | 2011-06-21 | Nissan Chemical Industries, Ltd. | Process for production of 2-(substituted phenyl)-3,3,3-trifluoropropene compound |
| WO2008066921A2 (en) * | 2006-11-30 | 2008-06-05 | Sensors For Medicine And Science, Inc. | Oxidation resistant indicator molecules |
| US8349858B2 (en) * | 2007-06-21 | 2013-01-08 | Merck Sharp & Dohme | Polycyclic guanine derivatives and use thereof |
| HK1200458A1 (en) * | 2011-07-26 | 2015-08-07 | Dow Agrosciences Llc | Methods of isolating 4-chloro-2-fluoro-3-substituted-phenylboronic acids |
| PL2797933T3 (pl) * | 2011-12-30 | 2018-01-31 | Dow Agrosciences Llc | Sposoby wytwarzania estrów pinakolowych kwasu 4-chloro-2-fluoro-3-podstawionego-fenyloboronowego oraz sposoby ich stosowania |
| RU2616621C2 (ru) * | 2011-12-30 | 2017-04-18 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы получения метил 4-амино-3-хлор-6-(4-хлор-2-фтор-3-метоксифенил)пиридин-2-карбоксилата |
-
2012
- 2012-12-20 PL PL12862457T patent/PL2797933T3/pl unknown
- 2012-12-20 WO PCT/US2012/070967 patent/WO2013101665A1/en not_active Ceased
- 2012-12-20 CA CA2861631A patent/CA2861631C/en active Active
- 2012-12-20 KR KR1020147020891A patent/KR102062343B1/ko active Active
- 2012-12-20 JP JP2014550379A patent/JP6290788B2/ja active Active
- 2012-12-20 MX MX2014008017A patent/MX341834B/es active IP Right Grant
- 2012-12-20 CN CN201280069312.7A patent/CN104114562A/zh active Pending
- 2012-12-20 AU AU2012362698A patent/AU2012362698B2/en active Active
- 2012-12-20 EP EP12862457.4A patent/EP2797933B1/en active Active
- 2012-12-20 US US13/722,471 patent/US8912339B2/en active Active
- 2012-12-20 NZ NZ627041A patent/NZ627041A/en unknown
- 2012-12-20 RU RU2014131414A patent/RU2625800C2/ru active
- 2012-12-20 BR BR112014016048A patent/BR112014016048B8/pt active IP Right Grant
- 2012-12-28 AR ARP120105068A patent/AR089539A1/es active IP Right Grant
-
2014
- 2014-06-26 IL IL233413A patent/IL233413A/en active IP Right Grant
- 2014-07-08 IN IN5647DEN2014 patent/IN2014DN05647A/en unknown
- 2014-07-22 CO CO14158850A patent/CO7020930A2/es unknown
- 2014-11-06 US US14/535,096 patent/US9422313B2/en active Active
-
2018
- 2018-02-08 JP JP2018021348A patent/JP2018104447A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7314849B2 (en) * | 2006-01-13 | 2008-01-01 | Dow Agrosciences Llc | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides |
| US7915200B2 (en) * | 2007-08-13 | 2011-03-29 | Dow Agrosciences Llc | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides |
| EP2181098B1 (en) * | 2007-08-30 | 2011-03-02 | Dow AgroSciences LLC | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides |
| EP2332914A1 (en) * | 2007-10-02 | 2011-06-15 | Dow AgroSciences LLC | Substituted 4-amino-picolinic acids and their use as herbicides |
| CN101970446A (zh) * | 2008-01-11 | 2011-02-09 | 陶氏益农公司 | 对1-氟-2-取代的-3-氯苯选择性脱质子化和官能化的方法 |
Non-Patent Citations (1)
| Title |
|---|
| ANDREW N. CAMMIDGE ET AL.: ""Application of the Suzuki Reaction as the Key Step in the Synthesis of a Novel Atropisomeric Biphenyl Derivative for Use as a Liquid Crystal Dopant"", 《J. ORG. CHEM.》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108273550A (zh) * | 2018-04-16 | 2018-07-13 | 苏州大学张家港工业技术研究院 | 对甲基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108373480A (zh) * | 2018-04-16 | 2018-08-07 | 苏州大学 | 利用对甲基苯胺基锂制备硼酸酯的方法 |
| CN108404984A (zh) * | 2018-04-16 | 2018-08-17 | 苏州大学 | 正丁基锂在催化醛和硼烷硼氢化反应中的应用 |
| CN108409772A (zh) * | 2018-04-16 | 2018-08-17 | 南通纺织丝绸产业技术研究院 | 基于醛制备硼酸酯的方法 |
| CN108558925A (zh) * | 2018-04-16 | 2018-09-21 | 南通纺织丝绸产业技术研究院 | 2,6-二异丙基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN116715689A (zh) * | 2023-06-09 | 2023-09-08 | 珠海市海瑞德生物科技有限公司 | 氟比洛芬及其中间体的合成方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8912339B2 (en) | 2014-12-16 |
| BR112014016048B8 (pt) | 2022-10-11 |
| CA2861631C (en) | 2021-05-04 |
| JP6290788B2 (ja) | 2018-03-07 |
| CA2861631A1 (en) | 2013-07-04 |
| US20150203514A1 (en) | 2015-07-23 |
| KR20140117442A (ko) | 2014-10-07 |
| MX2014008017A (es) | 2014-12-08 |
| IL233413A (en) | 2017-12-31 |
| IL233413A0 (en) | 2014-08-31 |
| RU2625800C2 (ru) | 2017-07-19 |
| WO2013101665A1 (en) | 2013-07-04 |
| JP2015507631A (ja) | 2015-03-12 |
| CO7020930A2 (es) | 2014-08-11 |
| AR089539A1 (es) | 2014-08-27 |
| US20130172565A1 (en) | 2013-07-04 |
| BR112014016048A2 (pt) | 2017-06-13 |
| EP2797933B1 (en) | 2017-08-16 |
| BR112014016048B1 (pt) | 2019-12-03 |
| AU2012362698B2 (en) | 2017-08-24 |
| NZ627041A (en) | 2016-07-29 |
| PL2797933T3 (pl) | 2018-01-31 |
| KR102062343B1 (ko) | 2020-01-02 |
| RU2014131414A (ru) | 2016-02-20 |
| EP2797933A1 (en) | 2014-11-05 |
| JP2018104447A (ja) | 2018-07-05 |
| BR112014016048A8 (pt) | 2017-07-04 |
| MX341834B (es) | 2016-09-05 |
| EP2797933A4 (en) | 2015-08-12 |
| AU2012362698A1 (en) | 2014-07-24 |
| US9422313B2 (en) | 2016-08-23 |
| IN2014DN05647A (https=) | 2015-04-03 |
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Legal Events
| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination |