KR102062343B1 - 4-클로로-2-플루오로-3-치환된-페닐보론산 피나콜 에스테르의 형성 방법 및 그의 사용 방법 - Google Patents
4-클로로-2-플루오로-3-치환된-페닐보론산 피나콜 에스테르의 형성 방법 및 그의 사용 방법 Download PDFInfo
- Publication number
- KR102062343B1 KR102062343B1 KR1020147020891A KR20147020891A KR102062343B1 KR 102062343 B1 KR102062343 B1 KR 102062343B1 KR 1020147020891 A KR1020147020891 A KR 1020147020891A KR 20147020891 A KR20147020891 A KR 20147020891A KR 102062343 B1 KR102062343 B1 KR 102062343B1
- Authority
- KR
- South Korea
- Prior art keywords
- chloro
- fluoro
- substituted
- solution
- phenylboronic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
- C07D213/807—Processes of preparation by oxidation of pyridines or condensed pyridines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/02—Lithium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161582173P | 2011-12-30 | 2011-12-30 | |
| US61/582,173 | 2011-12-30 | ||
| PCT/US2012/070967 WO2013101665A1 (en) | 2011-12-30 | 2012-12-20 | Methods of forming 4-chloro-2-fluoro-3-substituted-phenylboronic acid pinacol esters and methods of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140117442A KR20140117442A (ko) | 2014-10-07 |
| KR102062343B1 true KR102062343B1 (ko) | 2020-01-02 |
Family
ID=48695350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147020891A Active KR102062343B1 (ko) | 2011-12-30 | 2012-12-20 | 4-클로로-2-플루오로-3-치환된-페닐보론산 피나콜 에스테르의 형성 방법 및 그의 사용 방법 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8912339B2 (https=) |
| EP (1) | EP2797933B1 (https=) |
| JP (2) | JP6290788B2 (https=) |
| KR (1) | KR102062343B1 (https=) |
| CN (1) | CN104114562A (https=) |
| AR (1) | AR089539A1 (https=) |
| AU (1) | AU2012362698B2 (https=) |
| BR (1) | BR112014016048B8 (https=) |
| CA (1) | CA2861631C (https=) |
| CO (1) | CO7020930A2 (https=) |
| IL (1) | IL233413A (https=) |
| IN (1) | IN2014DN05647A (https=) |
| MX (1) | MX341834B (https=) |
| NZ (1) | NZ627041A (https=) |
| PL (1) | PL2797933T3 (https=) |
| RU (1) | RU2625800C2 (https=) |
| WO (1) | WO2013101665A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2797933T3 (pl) * | 2011-12-30 | 2018-01-31 | Dow Agrosciences Llc | Sposoby wytwarzania estrów pinakolowych kwasu 4-chloro-2-fluoro-3-podstawionego-fenyloboronowego oraz sposoby ich stosowania |
| RU2616621C2 (ru) * | 2011-12-30 | 2017-04-18 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы получения метил 4-амино-3-хлор-6-(4-хлор-2-фтор-3-метоксифенил)пиридин-2-карбоксилата |
| BR102014021960A2 (pt) | 2013-09-05 | 2015-09-15 | Univ Michigan State | métodos para a produção de arenos borilados |
| TW201625354A (zh) | 2014-06-16 | 2016-07-16 | 陶氏農業科學公司 | 用於製備氧硼基化芳烴之方法 |
| BR112017019207A2 (pt) * | 2015-05-22 | 2018-04-24 | Dow Agrosciences Llc | recuperação e/ou reutilização de catalisador de paládio após acoplamento de suzuki |
| CN108558925A (zh) * | 2018-04-16 | 2018-09-21 | 南通纺织丝绸产业技术研究院 | 2,6-二异丙基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108329339A (zh) * | 2018-04-16 | 2018-07-27 | 苏州大学张家港工业技术研究院 | 2,6-二甲基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108654692A (zh) * | 2018-04-16 | 2018-10-16 | 苏州大学 | 正丁基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN108503660A (zh) * | 2018-04-16 | 2018-09-07 | 苏州大学 | 苯胺基锂在催化醛和硼烷硼氢化反应中的应用 |
| CN108383863A (zh) * | 2018-04-16 | 2018-08-10 | 苏州大学 | 2,6-二异丙基苯胺基锂在制备硼酸酯中的应用 |
| CN108503659A (zh) * | 2018-04-16 | 2018-09-07 | 苏州大学 | 利用2,6-二异丙基苯胺基锂制备硼酸酯的方法 |
| CN108373480A (zh) * | 2018-04-16 | 2018-08-07 | 苏州大学 | 利用对甲基苯胺基锂制备硼酸酯的方法 |
| CN108409772A (zh) * | 2018-04-16 | 2018-08-17 | 南通纺织丝绸产业技术研究院 | 基于醛制备硼酸酯的方法 |
| CN108404984A (zh) * | 2018-04-16 | 2018-08-17 | 苏州大学 | 正丁基锂在催化醛和硼烷硼氢化反应中的应用 |
| CN108273550A (zh) * | 2018-04-16 | 2018-07-13 | 苏州大学张家港工业技术研究院 | 对甲基苯胺基锂在催化酮和硼烷硼氢化反应中的应用 |
| CN116715689B (zh) * | 2023-06-09 | 2025-12-12 | 珠海市海瑞德生物科技有限公司 | 氟比洛芬及其中间体的合成方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009029735A1 (en) | 2007-08-30 | 2009-03-05 | Dow Agrosciences Llc | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides |
| JP2009519982A (ja) | 2006-01-13 | 2009-05-21 | ダウ アグロサイエンシィズ エルエルシー | ６−（多置換アリール）−４−アミノピコリネートおよび除草剤としてのそれらの使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0986541A4 (en) * | 1997-04-09 | 2002-08-14 | Commw Scient Ind Res Org | METHOD FOR COVALENT BINDING ORGANIC COMPOUNDS USING DIBORANE DERIVATIVES |
| EA200702614A1 (ru) * | 2005-05-25 | 2008-04-28 | Майкробиа, Инк. | Способы получения 4-(бифенилил)азетидин-2-оналкилфосфиновых кислот |
| US7964758B2 (en) * | 2006-02-13 | 2011-06-21 | Nissan Chemical Industries, Ltd. | Process for production of 2-(substituted phenyl)-3,3,3-trifluoropropene compound |
| WO2008066921A2 (en) * | 2006-11-30 | 2008-06-05 | Sensors For Medicine And Science, Inc. | Oxidation resistant indicator molecules |
| US8349858B2 (en) * | 2007-06-21 | 2013-01-08 | Merck Sharp & Dohme | Polycyclic guanine derivatives and use thereof |
| ES2400405T3 (es) * | 2007-08-13 | 2013-04-09 | Dow Agrosciences Llc | 2-(Fenil 2-fluoro-substituido)-6-amino-5-cloro-4-pirimidinacarboxilatos y su uso como herbicidas |
| CA2699598C (en) * | 2007-10-02 | 2013-05-21 | Dow Agrosciences Llc | 2-substituted-6-amino-5-alkyl, alkenyl or alkynyl-4-pyrimidinecarboxylic acids and 6-substituted-4-amino-3-alkyl, alkenyl or alkynyl picolinic acids and their use as herbicides |
| UA104282C2 (ru) * | 2008-01-11 | 2014-01-27 | ДАУ АГРОСАЙЕНСИЗ ЕлЕлСи | Способ селективного депротонирования и введения заместителя к 1-фтор-2-замещенным-3-хлорбензолам |
| HK1200458A1 (en) * | 2011-07-26 | 2015-08-07 | Dow Agrosciences Llc | Methods of isolating 4-chloro-2-fluoro-3-substituted-phenylboronic acids |
| PL2797933T3 (pl) * | 2011-12-30 | 2018-01-31 | Dow Agrosciences Llc | Sposoby wytwarzania estrów pinakolowych kwasu 4-chloro-2-fluoro-3-podstawionego-fenyloboronowego oraz sposoby ich stosowania |
| RU2616621C2 (ru) * | 2011-12-30 | 2017-04-18 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Способы получения метил 4-амино-3-хлор-6-(4-хлор-2-фтор-3-метоксифенил)пиридин-2-карбоксилата |
-
2012
- 2012-12-20 PL PL12862457T patent/PL2797933T3/pl unknown
- 2012-12-20 WO PCT/US2012/070967 patent/WO2013101665A1/en not_active Ceased
- 2012-12-20 CA CA2861631A patent/CA2861631C/en active Active
- 2012-12-20 KR KR1020147020891A patent/KR102062343B1/ko active Active
- 2012-12-20 JP JP2014550379A patent/JP6290788B2/ja active Active
- 2012-12-20 MX MX2014008017A patent/MX341834B/es active IP Right Grant
- 2012-12-20 CN CN201280069312.7A patent/CN104114562A/zh active Pending
- 2012-12-20 AU AU2012362698A patent/AU2012362698B2/en active Active
- 2012-12-20 EP EP12862457.4A patent/EP2797933B1/en active Active
- 2012-12-20 US US13/722,471 patent/US8912339B2/en active Active
- 2012-12-20 NZ NZ627041A patent/NZ627041A/en unknown
- 2012-12-20 RU RU2014131414A patent/RU2625800C2/ru active
- 2012-12-20 BR BR112014016048A patent/BR112014016048B8/pt active IP Right Grant
- 2012-12-28 AR ARP120105068A patent/AR089539A1/es active IP Right Grant
-
2014
- 2014-06-26 IL IL233413A patent/IL233413A/en active IP Right Grant
- 2014-07-08 IN IN5647DEN2014 patent/IN2014DN05647A/en unknown
- 2014-07-22 CO CO14158850A patent/CO7020930A2/es unknown
- 2014-11-06 US US14/535,096 patent/US9422313B2/en active Active
-
2018
- 2018-02-08 JP JP2018021348A patent/JP2018104447A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009519982A (ja) | 2006-01-13 | 2009-05-21 | ダウ アグロサイエンシィズ エルエルシー | ６−（多置換アリール）−４−アミノピコリネートおよび除草剤としてのそれらの使用 |
| WO2009029735A1 (en) | 2007-08-30 | 2009-03-05 | Dow Agrosciences Llc | 2-(substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylates and their use as herbicides |
Non-Patent Citations (1)
| Title |
|---|
| J.Org.Chem, 1996, Vol. 61, No. 16, pp.5391-5399, |
Also Published As
| Publication number | Publication date |
|---|---|
| US8912339B2 (en) | 2014-12-16 |
| BR112014016048B8 (pt) | 2022-10-11 |
| CA2861631C (en) | 2021-05-04 |
| JP6290788B2 (ja) | 2018-03-07 |
| CA2861631A1 (en) | 2013-07-04 |
| US20150203514A1 (en) | 2015-07-23 |
| KR20140117442A (ko) | 2014-10-07 |
| MX2014008017A (es) | 2014-12-08 |
| IL233413A (en) | 2017-12-31 |
| IL233413A0 (en) | 2014-08-31 |
| RU2625800C2 (ru) | 2017-07-19 |
| WO2013101665A1 (en) | 2013-07-04 |
| JP2015507631A (ja) | 2015-03-12 |
| CO7020930A2 (es) | 2014-08-11 |
| AR089539A1 (es) | 2014-08-27 |
| US20130172565A1 (en) | 2013-07-04 |
| BR112014016048A2 (pt) | 2017-06-13 |
| EP2797933B1 (en) | 2017-08-16 |
| BR112014016048B1 (pt) | 2019-12-03 |
| CN104114562A (zh) | 2014-10-22 |
| AU2012362698B2 (en) | 2017-08-24 |
| NZ627041A (en) | 2016-07-29 |
| PL2797933T3 (pl) | 2018-01-31 |
| RU2014131414A (ru) | 2016-02-20 |
| EP2797933A1 (en) | 2014-11-05 |
| JP2018104447A (ja) | 2018-07-05 |
| BR112014016048A8 (pt) | 2017-07-04 |
| MX341834B (es) | 2016-09-05 |
| EP2797933A4 (en) | 2015-08-12 |
| AU2012362698A1 (en) | 2014-07-24 |
| US9422313B2 (en) | 2016-08-23 |
| IN2014DN05647A (https=) | 2015-04-03 |
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