CN103936854B - 抗il-17a单克隆抗体及其制备与应用 - Google Patents
抗il-17a单克隆抗体及其制备与应用 Download PDFInfo
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- CN103936854B CN103936854B CN201410178841.1A CN201410178841A CN103936854B CN 103936854 B CN103936854 B CN 103936854B CN 201410178841 A CN201410178841 A CN 201410178841A CN 103936854 B CN103936854 B CN 103936854B
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Description
Sample | Kon(1/MS) | Koff(1/S) | KD |
B55E | 1.377E+6 | 1.160E-4 | 8.425E-11 |
B510F1 | 4.178E+5 | 8.373E-5 | 2.004E-10 |
B112E | 4.760E+5 | 8.231E-5 | 1.729E-10 |
B113C | 2.396E+6 | 1.173E-4 | 4.894E-11 |
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CN201410178841.1A CN103936854B (zh) | 2014-04-30 | 2014-04-30 | 抗il-17a单克隆抗体及其制备与应用 |
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CN201410178841.1A CN103936854B (zh) | 2014-04-30 | 2014-04-30 | 抗il-17a单克隆抗体及其制备与应用 |
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CN103936854A CN103936854A (zh) | 2014-07-23 |
CN103936854B true CN103936854B (zh) | 2016-08-17 |
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Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11278618B2 (en) * | 2014-09-10 | 2022-03-22 | Novartis Ag | Use of IL-17 antagonists to inhibit the progression of structural damage in psoriatic arthritis patients |
WO2016082193A1 (zh) * | 2014-11-28 | 2016-06-02 | 中国医学科学院药物研究所 | 全人源抗人白介素17a单链抗体 |
CN108251431B (zh) * | 2015-03-05 | 2020-12-08 | 北京百特美博生物科技有限公司 | 双载体系统及其用途 |
CN105504062B (zh) * | 2015-12-25 | 2019-06-04 | 百泰生物药业有限公司 | 一种抗CD6单抗T1h的检测性抗体及应用 |
CN107236041B (zh) * | 2016-03-29 | 2020-07-24 | 舒泰神(北京)生物制药股份有限公司 | Il-17抗体 |
US20210309735A1 (en) * | 2018-07-31 | 2021-10-07 | Weiqun SHEN | Anti-il-17a antibodies and use thereof |
CN111303283A (zh) * | 2018-12-12 | 2020-06-19 | 上海君实生物医药科技股份有限公司 | 抗il-17a抗体及其应用 |
CN110655579B (zh) * | 2019-10-25 | 2020-07-24 | 北京东方百泰生物科技有限公司 | 一种新型抗ctla-4单克隆抗体及其应用 |
CN111848795B (zh) * | 2020-06-19 | 2021-03-12 | 北京东方百泰生物科技股份有限公司 | 一种抗il-17ra单克隆抗体及其应用 |
CN113150149B (zh) * | 2020-06-19 | 2021-10-08 | 北京东方百泰生物科技股份有限公司 | 一种抗il-17ra单克隆抗体的纯化方法 |
CN112891531B (zh) * | 2020-06-19 | 2021-10-08 | 北京东方百泰生物科技股份有限公司 | 一种抗il-17ra单克隆抗体的注射制剂 |
TW202241505A (zh) * | 2021-01-04 | 2022-11-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗il-17抗體治療自體免疫性疾病和炎症的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102905727A (zh) * | 2009-10-30 | 2013-01-30 | 詹森生物科技公司 | Il-17a拮抗剂 |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102905727A (zh) * | 2009-10-30 | 2013-01-30 | 詹森生物科技公司 | Il-17a拮抗剂 |
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Inventor after: Zhou Junjie Inventor after: Liu Fangjie Inventor after: Zhou Haiping Inventor after: Bai Yi Inventor after: Bai Xianhong Inventor before: Liu Zhigang Inventor before: Liu Fangjie Inventor before: Zhou Junjie Inventor before: Zhang Lei Inventor before: Peng Bo Inventor before: Guo Jingjing Inventor before: Bai Xianhong |
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Address after: 100080 room 3, building 4, building 75, No. 303, Haidian District, Beijing, Suzhou Street Patentee after: Beijing Jingyi Taixiang Technology Development Co.,Ltd. Patentee after: Beijing Dongfang Baitai Biotechnology Co., Ltd Address before: 100080 room 3, building 4, building 75, No. 303, Haidian District, Beijing, Suzhou Street Patentee before: Beijing Jingyi Taixiang Technology Development Co.,Ltd. Patentee before: Beijing Dongfang Biotech Co.,Ltd. |
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