CN103596582B - 药用组合物 - Google Patents

药用组合物 Download PDF

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Publication number
CN103596582B
CN103596582B CN201280027310.1A CN201280027310A CN103596582B CN 103596582 B CN103596582 B CN 103596582B CN 201280027310 A CN201280027310 A CN 201280027310A CN 103596582 B CN103596582 B CN 103596582B
Authority
CN
China
Prior art keywords
pharmaceutical composition
oxytocin
composition according
seq
cellulose ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280027310.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN103596582A (zh
Inventor
克斯廷·尤芙纳斯-莫伯格
A·卡尔松
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PeP-Tonic Medical AB
Original Assignee
PeP-Tonic Medical AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PeP-Tonic Medical AB filed Critical PeP-Tonic Medical AB
Publication of CN103596582A publication Critical patent/CN103596582A/zh
Application granted granted Critical
Publication of CN103596582B publication Critical patent/CN103596582B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN201280027310.1A 2011-04-14 2012-04-13 药用组合物 Expired - Fee Related CN103596582B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161475471P 2011-04-14 2011-04-14
SE1150324-0 2011-04-14
SE1150324A SE536091C2 (sv) 2011-04-14 2011-04-14 Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter
US61/475,471 2011-04-14
PCT/EP2012/056813 WO2012140216A1 (en) 2011-04-14 2012-04-13 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
CN103596582A CN103596582A (zh) 2014-02-19
CN103596582B true CN103596582B (zh) 2016-03-16

Family

ID=47008851

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280027310.1A Expired - Fee Related CN103596582B (zh) 2011-04-14 2012-04-13 药用组合物

Country Status (17)

Country Link
US (1) US9034821B2 (enExample)
EP (1) EP2696882B1 (enExample)
JP (1) JP5993442B2 (enExample)
KR (1) KR101940341B1 (enExample)
CN (1) CN103596582B (enExample)
AU (1) AU2012241805B2 (enExample)
BR (1) BR112013026153A2 (enExample)
CA (1) CA2832664C (enExample)
DK (1) DK2696882T3 (enExample)
ES (1) ES2535521T3 (enExample)
IL (1) IL228821A (enExample)
PL (1) PL2696882T3 (enExample)
RU (1) RU2605288C2 (enExample)
SE (1) SE536091C2 (enExample)
SG (1) SG194074A1 (enExample)
WO (1) WO2012140216A1 (enExample)
ZA (1) ZA201308157B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014057092A1 (en) * 2012-10-12 2014-04-17 Pep-Tonic Medical Ab Novel use of a composition comprising oxytocin
PL3242676T3 (pl) 2015-01-07 2024-07-15 Tonix Pharma Limited Preparaty oksytocyny zawierające magnez i sposoby ich stosowania
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
KR20180066071A (ko) * 2015-10-30 2018-06-18 데이진 화-마 가부시키가이샤 비점막 투여용 의약 조성물
HRP20250215T1 (hr) 2016-04-12 2025-06-20 Tonix Pharma Limited Formulacije oksitocina koje sadrže magnezij i postupci upotrebe
SE1750680A1 (en) * 2017-05-30 2018-12-01 Peptonic Medical Ab Composition for treating or preventing climacteric disorders
US20200093884A1 (en) * 2018-09-20 2020-03-26 Mark C. Manning Stable intranasal formulations of carbetocin
CN110169377B (zh) * 2019-06-27 2021-09-14 浙江海洋大学 黄姑鱼的人工催产受精方法
SE547797C2 (en) 2023-09-25 2025-11-25 Letavis Ab Stimulation of plant germination

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001078758A1 (en) * 2000-04-18 2001-10-25 Entretech Medical Ab Use of substances with oxytocin activity against climacteric disorders
WO2008042452A1 (en) * 2006-09-29 2008-04-10 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions comprising oxytocin or an analog for the treatment of autism
WO2010118888A1 (en) * 2009-04-17 2010-10-21 Merz Pharma Gmbh & Co. Kgaa Formulation for stabilizing proteins, which is free of mammalian excipients

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3076797A (en) 1957-07-22 1963-02-05 Roussel Uclaf Process of producing oxytocin and intermediates obtained thereby
US2938991A (en) 1957-10-01 1960-05-31 Candace Inc Electric mattress pad
JPS61126014A (ja) * 1984-11-22 1986-06-13 Teijin Ltd 経鼻投与用水性液剤
SE9003712L (sv) 1990-11-22 1992-01-07 Kabi Pharmacia Ab Gelbildande flytande baerarkomposition samt anvaendning daerav i farmaceutiska kompositioner
JP3179538B2 (ja) * 1990-12-11 2001-06-25 ノバルティス アクチエンゲゼルシャフト 安定なヒトカルシトニンの水性溶液
GB9326354D0 (en) 1993-12-23 1994-02-23 British Aerospace Methods and apparatus for the testing,monitoring and improvement of manufacturing process effectiveness
SE9400918L (sv) * 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
US5833647A (en) * 1995-10-10 1998-11-10 The Penn State Research Foundation Hydrogels or lipogels with enhanced mass transfer for transdermal drug delivery
CN1155368C (zh) 1996-02-27 2004-06-30 帝人株式会社 鼻腔给药的粉剂组合物
SE9701161D0 (sv) 1997-03-27 1997-03-27 Karolinska Innovations Ab New use I
SE9701162D0 (sv) 1997-03-27 1997-03-27 Karolinska Innovations Ab New use II
SE9701184D0 (sv) 1997-04-01 1997-04-01 Karolinska Innovations Ab Substanser för att åstadkomma preferens och skapa acceptans
SE9803272D0 (sv) 1998-09-25 1998-09-25 Kerstin Uvnaes Moberg A drug for cell regeneration
SE0100684D0 (sv) 2001-02-28 2001-02-28 Kerstin Uvnaes Moberg New subject-matter
SE0102184D0 (sv) 2001-06-19 2001-06-19 Uvnaes Moberg Kerstin New subject-matter
SE0102910D0 (sv) * 2001-08-31 2001-08-31 Moberg Kerstin Uvnaes New use
JO2492B1 (en) * 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
US7884076B2 (en) * 2003-11-06 2011-02-08 The Trustees Of Columbia University In The City Of New York Multipeptide regimen for the treatment of autistic spectrum, behavioral, emotional and visceral inflammation/autoimmune disorders
CA2570599C (en) * 2004-06-24 2012-03-27 Idexx Laboratories, Inc. Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001078758A1 (en) * 2000-04-18 2001-10-25 Entretech Medical Ab Use of substances with oxytocin activity against climacteric disorders
WO2008042452A1 (en) * 2006-09-29 2008-04-10 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions comprising oxytocin or an analog for the treatment of autism
WO2010118888A1 (en) * 2009-04-17 2010-10-21 Merz Pharma Gmbh & Co. Kgaa Formulation for stabilizing proteins, which is free of mammalian excipients

Also Published As

Publication number Publication date
SE1150324A1 (sv) 2012-10-15
SG194074A1 (en) 2013-11-29
EP2696882A1 (en) 2014-02-19
IL228821A (en) 2016-08-31
CN103596582A (zh) 2014-02-19
DK2696882T3 (en) 2015-04-27
SE536091E5 (enExample) 2015-04-21
US9034821B2 (en) 2015-05-19
ES2535521T3 (es) 2015-05-12
HK1189158A1 (en) 2014-05-30
IL228821A0 (en) 2013-12-31
WO2012140216A1 (en) 2012-10-18
RU2605288C2 (ru) 2016-12-20
AU2012241805B2 (en) 2016-08-11
CA2832664C (en) 2020-03-24
US20140171369A1 (en) 2014-06-19
PL2696882T3 (pl) 2015-08-31
KR101940341B1 (ko) 2019-01-18
AU2012241805A1 (en) 2013-10-24
SE536091C2 (sv) 2013-04-30
JP5993442B2 (ja) 2016-09-14
ZA201308157B (en) 2015-01-28
BR112013026153A2 (pt) 2019-09-17
RU2013147739A (ru) 2015-05-20
EP2696882B1 (en) 2015-03-04
CA2832664A1 (en) 2012-10-18
KR20140019830A (ko) 2014-02-17
JP2014515747A (ja) 2014-07-03

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160316