CN103534355A - 条件性表达蛋白质的载体 - Google Patents

条件性表达蛋白质的载体 Download PDF

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CN103534355A
CN103534355A CN201280021577.XA CN201280021577A CN103534355A CN 103534355 A CN103534355 A CN 103534355A CN 201280021577 A CN201280021577 A CN 201280021577A CN 103534355 A CN103534355 A CN 103534355A
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transcription factor
vector
proteins
ligand
sequence
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Chinese (zh)
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J·F·罗斯
C·C·瑞德
B·库斯博特森
S·查达
W·E·佛格勒
F·哈兹
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University of Pittsburgh
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University of Pittsburgh
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    • A61K48/0025Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
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    • A61K48/0066Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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CN201280021577.XA 2011-03-04 2012-03-02 条件性表达蛋白质的载体 Pending CN103534355A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161449536P 2011-03-04 2011-03-04
US61/449,536 2011-03-04
US201161478881P 2011-04-25 2011-04-25
US61/478,881 2011-04-25
US201161490535P 2011-05-26 2011-05-26
US61/490,535 2011-05-26
US201161562342P 2011-11-21 2011-11-21
US61/562,342 2011-11-21
PCT/US2012/027515 WO2012122025A2 (en) 2011-03-04 2012-03-02 Vectors conditionally expressing protein

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CN103534355A true CN103534355A (zh) 2014-01-22

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EP (2) EP2681327B1 (enExample)
JP (3) JP6189754B2 (enExample)
CN (1) CN103534355A (enExample)
AU (1) AU2012225749B2 (enExample)
CA (1) CA2828411A1 (enExample)
SG (2) SG192856A1 (enExample)
TW (1) TWI582108B (enExample)
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JP6189754B2 (ja) 2017-08-30
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US9402919B2 (en) 2016-08-02

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