ATE293699T1 - Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand - Google Patents

Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand

Info

Publication number
ATE293699T1
ATE293699T1 AT96904817T AT96904817T ATE293699T1 AT E293699 T1 ATE293699 T1 AT E293699T1 AT 96904817 T AT96904817 T AT 96904817T AT 96904817 T AT96904817 T AT 96904817T AT E293699 T1 ATE293699 T1 AT E293699T1
Authority
AT
Austria
Prior art keywords
receptor
nucleotide sequence
expression cassette
target
polypeptide
Prior art date
Application number
AT96904817T
Other languages
English (en)
Inventor
Stephen Arthur Goff
Lyle Dean Crossland
Laura Stein Privalle
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Application granted granted Critical
Publication of ATE293699T1 publication Critical patent/ATE293699T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217—Gene switch
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237—Externally regulated expression systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C12N15/8289—Male sterility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C12N15/829—Female sterility
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Endocrinology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT96904817T 1995-03-03 1996-02-19 Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand ATE293699T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39803795A 1995-03-03 1995-03-03
PCT/EP1996/000686 WO1996027673A1 (en) 1995-03-03 1996-02-19 Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand

Publications (1)

Publication Number Publication Date
ATE293699T1 true ATE293699T1 (de) 2005-05-15

Family

ID=23573749

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96904817T ATE293699T1 (de) 1995-03-03 1996-02-19 Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand

Country Status (10)

Country Link
US (3) US5880333A (de)
EP (1) EP0813604B1 (de)
JP (1) JPH11500922A (de)
AT (1) ATE293699T1 (de)
AU (1) AU703124B2 (de)
CA (1) CA2213340C (de)
DE (1) DE69634630T2 (de)
ES (1) ES2237764T3 (de)
HU (1) HUP9800353A3 (de)
WO (1) WO1996027673A1 (de)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901677D0 (en) 1989-01-26 1989-03-15 Ici Plc Hybrid seed production
WO1996027673A1 (en) 1995-03-03 1996-09-12 Novartis Ag Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand
JPH11506319A (ja) 1995-05-26 1999-06-08 ゼネカ・リミテッド エクジソンレセプターを含む遺伝子スイッチ
HUP9900029A3 (en) * 1995-10-10 2001-02-28 Novartis Ag Juvenile hormone or one of its agonists as a chemical ligand to control gene expression in plants by receptor mediated transactivation
US6610828B1 (en) 1996-05-24 2003-08-26 Syngenta Limited Heliothis ecdysone receptor
EP0823480A1 (de) * 1996-08-06 1998-02-11 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kontrollierte Genexpression in Pflanzen
GB9703681D0 (en) * 1997-02-21 1997-04-09 Gene Shears Pty Ltd Protein complemention
US6784340B1 (en) 1998-01-28 2004-08-31 The Rockefeller University Chemical inducible promoter used to obtain transgenic plants with a silent marker
US6683230B1 (en) 1998-02-20 2004-01-27 Syngenta Limited Hybrid seed production
US6333318B1 (en) * 1998-05-14 2001-12-25 The Salk Institute For Biological Studies Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
US6258603B1 (en) * 1998-06-17 2001-07-10 Rohm And Haas Company Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
JP2002525053A (ja) 1998-09-10 2002-08-13 パイオニア ハイ−ブレッド インターナショナル， インコーポレイテッド エクジソンレセプターおよびそれらの使用のための方法
GB9828660D0 (en) 1998-12-24 1999-02-17 Cambridge Advanced Tech Control of gene expression in eukaryotes
US7420049B2 (en) * 1999-06-18 2008-09-02 Ceres, Inc. Sequence-determined DNA fragments encoding AP2 domain proteins
US20060235218A1 (en) * 1999-12-08 2006-10-19 Nickolai Alexandrov Sequence-determined DNA fragments encoding thioredoxin proteins
AU2001241682A1 (en) * 2000-02-24 2001-09-03 The Salk Institute For Biological Studies Gene expression system based on chimeric receptors
EP1263977A2 (de) * 2000-02-28 2002-12-11 Yale University Verfahren und zusammensetzungen zur reduction oder eliminierung der verbreitung eines transgens
US20040033600A1 (en) * 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
ATE338135T1 (de) * 2000-03-22 2006-09-15 Rheogene Holdings Inc Induziertes genexpressionssystem basierend auf ecdysonrezeptoren
AU2011213797B2 (en) * 2000-03-22 2013-05-02 Intrexon Corporation Ecdysone receptor-based inducible gene expression system
JP2003528889A (ja) * 2000-03-24 2003-09-30 シティ・オブ・ホープ Ｓｘｒ活性の改変により薬物クリアランス機序を調節する方法
US6849776B1 (en) * 2000-07-14 2005-02-01 Unicrop Ltd Molecular control of transgene segregation and its escape by a recoverable block of function (RBF) system
US8105825B2 (en) 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
US6576422B1 (en) * 2000-10-17 2003-06-10 Rohm And Haas Company Method for identifying products employing gene expression
WO2002061102A2 (en) * 2000-10-24 2002-08-08 Syngenta Participations Ag Control of gene expression in plants
AU2002243645A1 (en) 2001-01-22 2002-07-30 Sangamo Biosciences, Inc. Zinc finger proteins for dna binding and gene regulation in plants
EP1534738B1 (de) * 2001-02-20 2012-06-20 Intrexon Corporation Neue substitutionsmutantenrezeptoren und ihre verwendung in einem induzierbaren genexpressionsystem auf grundlage eines nukleären rezeptors
AU2012200136B2 (en) * 2001-02-20 2012-12-13 Intrexon Corporation Chimeric retinoid X receptors and their use in a novel ecdysone receptor-based inducible gene expression system
PT1456346E (pt) 2001-02-20 2012-05-02 Intrexon Corp Novo sistema de expressão de genes induzido baseado no recetor de ecdisona / recetor x retinoide invertebrado
EP1572862B1 (de) * 2001-02-20 2012-08-01 Intrexon Corporation Chimäre retinoid-x-rezeptoren und ihre verwendung in einem neuen induzierbaren genexpressionssystem auf ecdysonrezeptor-basis
CA2445796C (en) 2001-02-20 2014-09-16 Rheogene, Inc. Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
DE10109354A1 (de) * 2001-02-27 2002-09-05 Icon Genetics Ag Rekombinante virale Schaltersysteme
GB0122828D0 (en) * 2001-09-21 2001-11-14 Univ Cambridge Tech Gene expression construct
CA2820170C (en) 2001-09-26 2016-07-05 Intrexon Corporation Whitefly ecdysone receptor nucleic acids, polypeptides, and uses thereof
CA2459827C (en) 2001-09-26 2013-09-03 Subba Reddy Palli Leafhopper ecdysone receptor nucleic acids, polypeptides, and uses thereof
US20050260585A1 (en) * 2002-03-19 2005-11-24 Cedric Szpirer Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms
US7375093B2 (en) 2002-07-05 2008-05-20 Intrexon Corporation Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US20060211853A1 (en) * 2002-07-15 2006-09-21 Nickolai Alexandrov Sequence-determined DNA fragments encoding prothymosin/parathymosin proteins
EP1546337A4 (de) * 2002-09-17 2006-10-11 Ceres Inc Biologisches eindämmungssystem
US7476777B2 (en) * 2002-09-17 2009-01-13 Ceres, Inc. Biological containment system
US7683238B2 (en) 2002-11-12 2010-03-23 iBio, Inc. and Fraunhofer USA, Inc. Production of pharmaceutically active proteins in sprouted seedlings
ES2531125T3 (es) 2003-02-03 2015-03-10 Ibio Inc Sistema para la expresión de genes en plantas
US7304161B2 (en) 2003-02-10 2007-12-04 Intrexon Corporation Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
US7304162B2 (en) * 2003-02-21 2007-12-04 Intrexon Corporation Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7456315B2 (en) 2003-02-28 2008-11-25 Intrexon Corporation Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
AU2003247160A1 (en) * 2003-07-07 2005-01-21 Dhara Vegetable Oil And Foods Company Limited A method for obtaining improved fertility restorer lines for transgenic male sterile crop plants and a dna construct for use in said method
EP1646721B1 (de) * 2003-07-08 2011-11-16 Syngenta Limited Verfahren zur selektiven herstellung männlich- oder weiblich-steriler pflanzen
DK1682667T3 (da) * 2003-11-10 2010-08-23 Icon Genetics Gmbh RNA-virus afledt plantekspressionssystem
US7935510B2 (en) 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
JP4517347B2 (ja) * 2004-07-02 2010-08-04 国立大学法人北海道大学 植物を用いたエストロゲン様物質の検出方法
WO2007050625A1 (en) * 2005-10-25 2007-05-03 Ceres, Inc. Modulation of triterpenoid content in plants
EP1866418A2 (de) * 2005-02-22 2007-12-19 Ceres Inc. Modulation pflanzlicher alkaloide
WO2006115575A1 (en) * 2005-04-20 2006-11-02 Ceres Inc. Regulatory regions from papaveraceae
WO2006133461A1 (en) * 2005-06-08 2006-12-14 Ceres Inc. Identification of terpenoid-biosynthesis related regulatory protein-regulatory region associations
US8115059B1 (en) 2005-07-22 2012-02-14 University Of Kentucky Research Foundation Gene expression modulation system for use in plants and method for modulating gene expression in plants
WO2007041536A2 (en) * 2005-09-30 2007-04-12 Ceres, Inc. Modulating plant tocopherol levels
WO2007055826A1 (en) * 2005-11-04 2007-05-18 Ceres, Inc. Modulation of fertility in monocots
US8878002B2 (en) * 2005-12-09 2014-11-04 Council Of Scientific And Industrial Research Nucleic acids and methods for producing seeds with a full diploid complement of the maternal genome in the embryo
US20070199090A1 (en) * 2006-02-22 2007-08-23 Nestor Apuya Modulating alkaloid biosynthesis
WO2007117693A2 (en) * 2006-04-07 2007-10-18 Ceres, Inc. Regulatory protein-regulatory region associations related to alkaloid biosynthesis
JP4814686B2 (ja) * 2006-04-24 2011-11-16 岩手県 雌雄配偶子形成不全植物の作成方法
EP2444413A1 (de) 2006-08-04 2012-04-25 Verenium Corporation Verfahren für Öl- oder Gas-Bohrungen, Fluten und/oder "Fracturing"
ES2438268T3 (es) 2006-09-21 2014-01-16 Verenium Corporation Fitasas, ácidos nucleicos que las codifican y métodos para su producción y uso
US7745698B2 (en) 2006-11-16 2010-06-29 Wisconsin Alumni Research Foundation Peptide extension for enhancement of transgene expression in chloroplasts
DK2479266T3 (en) 2006-12-21 2016-06-20 Basf Enzymes Llc Amylases and glucoamylases, nucleic acids encoding them, and methods of making and using the same
EP3357904B1 (de) 2007-05-29 2022-07-06 Precigen, Inc. Chirale diachylhydrazin-liganden zur modulation der expression exogener gene über einen ecdyson-rezeptorkomplex
US7910802B2 (en) * 2007-08-03 2011-03-22 Pioneer Hi-Bred International, Inc. MSCA1 nucleotide sequences impacting plant male fertility and method of using same
US7919676B2 (en) * 2007-08-03 2011-04-05 Pioneer Hi-Bred International, Inc. Msca1 nucleotide sequences impacting plant male fertility and method of using same
US7915478B2 (en) 2007-08-03 2011-03-29 Pioneer Hi-Bred International, Inc. Msca1 nucleotide sequences impacting plant male fertility and method of using same
WO2009023755A1 (en) * 2007-08-15 2009-02-19 Wisconsin Alumni Research Foundation Late blight resistance gene from wild potato
EP2183355B1 (de) 2007-09-17 2016-01-27 Rohm and Haas Company Zusammensetzungen und verfahren zur modifizierung physiologischer reaktionen in pflanzen
EP2205249B1 (de) 2007-09-28 2018-11-07 Intrexon Corporation Therapeutische genschalterkonstrukte und bioreaktoren zur expression biotherapeutischer moleküle und ihre verwendung
JP5858393B2 (ja) * 2008-02-01 2016-02-10 国立大学法人神戸大学 抗体の可変領域を用いた新規な遺伝子発現調節方法
BRPI0908747A2 (pt) 2008-03-14 2023-04-18 Intrexon Corp Ligantes esteróides e seu uso em modulação de comutador genético
FR2930340B1 (fr) * 2008-04-22 2013-03-22 Total Sa Procede d'echantillonage de sulfure d'hydrogene.
JP2012519486A (ja) 2009-03-05 2012-08-30 ローム アンド ハース カンパニー 植物におけるエチレン感受性を調節する鍵となるエチレンホルモンシグナル伝達経路タンパク質の標的ターンオーバーの制御
AU2010249500B2 (en) 2009-05-21 2016-03-24 Basf Enzymes Llc Phytases, nucleic acids encoding them and methods for making and using them
CA2794196A1 (en) 2010-03-23 2011-09-29 Intrexon Corporation Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof
US9096871B2 (en) 2010-10-06 2015-08-04 Bp Corporation North America Inc. Variant CBH I polypeptides with reduced product inhibition
SG10201600912SA (en) 2011-03-04 2016-03-30 Intrexon Corp Vectors conditionally expressing protein
UY34014A (es) * 2011-04-15 2012-11-30 Dow Agrosciences Llc Genes sintéticos para expresar proteínas en células de maíz, construcciones, plantas transgénicas, métodos para controlar pestes y composiciones
PL2701487T3 (pl) 2011-04-29 2018-01-31 Bangladesh Jute Res Institute Polinukleotydy kodujące enzymy szlaku biosyntezy ligniny juty
KR102076728B1 (ko) 2012-02-02 2020-02-12 다우 아그로사이언시즈 엘엘씨 식물 전사활성화 상호작용 모티프 및 그의 용도
NZ712167A (en) 2013-03-15 2018-05-25 Intrexon Corp Boron-containing diacylhydrazines
EP2781151A1 (de) 2013-03-18 2014-09-24 Bayer CropScience AG Verfahren zum Trennen von Hybridsaat von einer Mischung aus saatbiologischen Steuerungsmitteln
WO2015009760A1 (en) 2013-07-15 2015-01-22 Donald Danforth Plant Science Center Enhanced oil production and stress tolerance in plants
US9944659B2 (en) 2014-09-17 2018-04-17 Intrexon Corporation Boron-containing diacylhydrazine compounds
UY37343A (es) 2016-07-25 2018-02-28 Intrexon Corp Control del fenotipo en plantas
WO2018076335A1 (en) 2016-10-31 2018-05-03 Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences Compositions and methods for enhancing abiotic stress tolerance
CA3042706A1 (en) 2016-11-09 2018-05-17 Intrexon Corporation Frataxin expression constructs
WO2018132494A1 (en) 2017-01-10 2018-07-19 Intrexon Corporation Modulating expression of polypeptides via new gene switch expression systems
IL306102A (en) 2017-06-07 2023-11-01 Precigen Inc Expression of new cell markers
KR20200128703A (ko) 2018-03-06 2020-11-16 프레시전 인코포레이티드 B형 간염 백신 및 이의 용도

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833080A (en) * 1985-12-12 1989-05-23 President And Fellows Of Harvard College Regulation of eucaryotic gene expression
GB8901677D0 (en) * 1989-01-26 1989-03-15 Ici Plc Hybrid seed production
US5262300A (en) * 1988-11-30 1993-11-16 The Salk Institute For Biological Studies Receptors: their identification, characterization, preparation and use
DE69132411T2 (de) * 1990-02-09 2001-06-07 Salk Inst For Biolog Studies L Retinoid-rezeptor-zusammensetzungen und verfahren
ATE220421T1 (de) * 1990-02-26 2002-07-15 Univ Leland Stanford Junior Identifizierung und expression von insekten- steroidrezeptor-dns-sequenzen
EP0522054A4 (en) * 1990-03-22 1993-02-10 The Salk Institute For Biological Studies Insect retinoid receptor compositions and methods
CA2274870C (en) * 1990-06-12 2003-02-04 Pioneer Hi-Bred International, Inc. Control of microsporogenesis by externally inducible promoter sequences
AU679899B2 (en) * 1991-03-18 1997-07-17 Salk Institute For Biological Studies, The Response element compositions and assays employing same
JPH07501928A (ja) * 1991-08-08 1995-03-02 ジェネンテク，インコーポレイテッド 哺乳類の細胞における遺伝子のエクジステロイド依存調節
WO1993009237A1 (en) * 1991-11-05 1993-05-13 Sandoz Ltd. Improved supersweet corn
GB9123554D0 (en) * 1991-11-06 1992-01-02 Hamilton John G Ventilation device
AU3901993A (en) * 1992-04-13 1993-11-18 Zeneca Limited Dna constructs and plants incorporating them
WO1993023431A1 (en) * 1992-05-14 1993-11-25 Baylor College Of Medicine Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy
WO1994001558A2 (en) * 1992-07-02 1994-01-20 The Salk Institute For Biological Studies Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor
US5409823A (en) * 1992-09-24 1995-04-25 Ciba-Geigy Corporation Methods for the production of hybrid seed
US5691196A (en) * 1992-12-31 1997-11-25 American Cyanamid Company Recombinant nucleic acid containing a response element
US5707798A (en) * 1993-07-13 1998-01-13 Novo Nordisk A/S Identification of ligands by selective amplification of cells transfected with receptors
WO1996027673A1 (en) 1995-03-03 1996-09-12 Novartis Ag Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand
JPH11506319A (ja) * 1995-05-26 1999-06-08 ゼネカ・リミテッド エクジソンレセプターを含む遺伝子スイッチ

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HUP9800353A3 (en) 2001-01-29
DE69634630D1 (de) 2005-05-25
CA2213340A1 (en) 1996-09-12
US20010022004A1 (en) 2001-09-13
AU4878296A (en) 1996-09-23
ES2237764T3 (es) 2005-08-01
US5880333A (en) 1999-03-09
DE69634630T2 (de) 2005-11-10
EP0813604A1 (de) 1997-12-29
HUP9800353A2 (hu) 1998-05-28
EP0813604B1 (de) 2005-04-20
US6939711B2 (en) 2005-09-06
WO1996027673A1 (en) 1996-09-12
JPH11500922A (ja) 1999-01-26
CA2213340C (en) 2011-07-26
US6147282A (en) 2000-11-14
AU703124B2 (en) 1999-03-18

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