DE69634630D1 - Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand - Google Patents
Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligandInfo
- Publication number
- DE69634630D1 DE69634630D1 DE69634630T DE69634630T DE69634630D1 DE 69634630 D1 DE69634630 D1 DE 69634630D1 DE 69634630 T DE69634630 T DE 69634630T DE 69634630 T DE69634630 T DE 69634630T DE 69634630 D1 DE69634630 D1 DE 69634630D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- nucleotide sequence
- expression cassette
- target
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/8289—Male sterility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/829—Female sterility
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39803795A | 1995-03-03 | 1995-03-03 | |
US398037 | 1995-03-03 | ||
PCT/EP1996/000686 WO1996027673A1 (en) | 1995-03-03 | 1996-02-19 | Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69634630D1 true DE69634630D1 (de) | 2005-05-25 |
DE69634630T2 DE69634630T2 (de) | 2005-11-10 |
Family
ID=23573749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69634630T Expired - Lifetime DE69634630T2 (de) | 1995-03-03 | 1996-02-19 | Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand |
Country Status (10)
Country | Link |
---|---|
US (3) | US5880333A (de) |
EP (1) | EP0813604B1 (de) |
JP (1) | JPH11500922A (de) |
AT (1) | ATE293699T1 (de) |
AU (1) | AU703124B2 (de) |
CA (1) | CA2213340C (de) |
DE (1) | DE69634630T2 (de) |
ES (1) | ES2237764T3 (de) |
HU (1) | HUP9800353A3 (de) |
WO (1) | WO1996027673A1 (de) |
Families Citing this family (93)
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GB8901677D0 (en) | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
CA2213340C (en) | 1995-03-03 | 2011-07-26 | Novartis Ag | Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand |
JPH11506319A (ja) | 1995-05-26 | 1999-06-08 | ゼネカ・リミテッド | エクジソンレセプターを含む遺伝子スイッチ |
IL123796A0 (en) * | 1995-10-10 | 1998-10-30 | Novartis Ag | Juvenile hormone or one of its agonists as a chemical ligand to control gene expression in plants by receptor mediated transactivation |
US6610828B1 (en) | 1996-05-24 | 2003-08-26 | Syngenta Limited | Heliothis ecdysone receptor |
EP0823480A1 (de) * | 1996-08-06 | 1998-02-11 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Kontrollierte Genexpression in Pflanzen |
GB9703681D0 (en) * | 1997-02-21 | 1997-04-09 | Gene Shears Pty Ltd | Protein complemention |
US6784340B1 (en) | 1998-01-28 | 2004-08-31 | The Rockefeller University | Chemical inducible promoter used to obtain transgenic plants with a silent marker |
BR9908126A (pt) | 1998-02-20 | 2000-10-24 | Zeneca Ltd | Produção de semente hìbrida |
US6333318B1 (en) | 1998-05-14 | 2001-12-25 | The Salk Institute For Biological Studies | Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto |
US6258603B1 (en) * | 1998-06-17 | 2001-07-10 | Rohm And Haas Company | Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
US6504082B1 (en) | 1998-09-10 | 2003-01-07 | Pioneer Hi-Bred International, Inc. | Ecdysone receptors and methods for their use |
GB9828660D0 (en) | 1998-12-24 | 1999-02-17 | Cambridge Advanced Tech | Control of gene expression in eukaryotes |
US7420049B2 (en) * | 1999-06-18 | 2008-09-02 | Ceres, Inc. | Sequence-determined DNA fragments encoding AP2 domain proteins |
US20060235218A1 (en) * | 1999-12-08 | 2006-10-19 | Nickolai Alexandrov | Sequence-determined DNA fragments encoding thioredoxin proteins |
AU2001241682A1 (en) * | 2000-02-24 | 2001-09-03 | The Salk Institute For Biological Studies | Gene expression system based on chimeric receptors |
EP1263977A2 (de) | 2000-02-28 | 2002-12-11 | Yale University | Verfahren und zusammensetzungen zur reduction oder eliminierung der verbreitung eines transgens |
AU2011213797B2 (en) * | 2000-03-22 | 2013-05-02 | Intrexon Corporation | Ecdysone receptor-based inducible gene expression system |
US20040033600A1 (en) | 2001-03-21 | 2004-02-19 | Palli Subba Reddy | Ecdysone receptor-based inducible gene expression system |
AU2001249315A1 (en) | 2000-03-22 | 2001-10-03 | Rheogene, Inc. | Ecdysone receptor-based inducible gene expression system |
WO2001072837A2 (en) * | 2000-03-24 | 2001-10-04 | City Of Hope | Methods of modulating drug clearance mechanisms by altering sxr activity |
US6849776B1 (en) * | 2000-07-14 | 2005-02-01 | Unicrop Ltd | Molecular control of transgene segregation and its escape by a recoverable block of function (RBF) system |
US8105825B2 (en) | 2000-10-03 | 2012-01-31 | Intrexon Corporation | Multiple inducible gene regulation system |
US6576422B1 (en) * | 2000-10-17 | 2003-06-10 | Rohm And Haas Company | Method for identifying products employing gene expression |
AU2002251724B2 (en) | 2000-10-24 | 2007-06-21 | Syngenta Participations Ag | Control of gene expression in plants |
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CA2459807C (en) * | 2001-09-26 | 2013-09-03 | Jianzhong Zhang | Whitefly ecdysone receptor nucleic acids, polypeptides, and uses thereof |
CA2477194A1 (en) * | 2002-03-19 | 2003-09-25 | Universite Libre De Bruxelles | Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms |
US7375093B2 (en) | 2002-07-05 | 2008-05-20 | Intrexon Corporation | Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
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GB9123554D0 (en) * | 1991-11-06 | 1992-01-02 | Hamilton John G | Ventilation device |
AU3901993A (en) * | 1992-04-13 | 1993-11-18 | Zeneca Limited | Dna constructs and plants incorporating them |
ATE365209T1 (de) * | 1992-05-14 | 2007-07-15 | Baylor College Medicine | Mutierte steroidhormonrezeptoren, methoden für ihre benutzung und molekularer schalter für gentherapie |
WO1994001558A2 (en) * | 1992-07-02 | 1994-01-20 | The Salk Institute For Biological Studies | Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor |
US5409823A (en) * | 1992-09-24 | 1995-04-25 | Ciba-Geigy Corporation | Methods for the production of hybrid seed |
US5691196A (en) * | 1992-12-31 | 1997-11-25 | American Cyanamid Company | Recombinant nucleic acid containing a response element |
US5707798A (en) * | 1993-07-13 | 1998-01-13 | Novo Nordisk A/S | Identification of ligands by selective amplification of cells transfected with receptors |
CA2213340C (en) | 1995-03-03 | 2011-07-26 | Novartis Ag | Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand |
JPH11506319A (ja) * | 1995-05-26 | 1999-06-08 | ゼネカ・リミテッド | エクジソンレセプターを含む遺伝子スイッチ |
-
1996
- 1996-02-19 CA CA2213340A patent/CA2213340C/en not_active Expired - Fee Related
- 1996-02-19 AT AT96904817T patent/ATE293699T1/de not_active IP Right Cessation
- 1996-02-19 AU AU48782/96A patent/AU703124B2/en not_active Ceased
- 1996-02-19 DE DE69634630T patent/DE69634630T2/de not_active Expired - Lifetime
- 1996-02-19 EP EP96904817A patent/EP0813604B1/de not_active Expired - Lifetime
- 1996-02-19 JP JP8526556A patent/JPH11500922A/ja active Pending
- 1996-02-19 WO PCT/EP1996/000686 patent/WO1996027673A1/en active IP Right Grant
- 1996-02-19 ES ES96904817T patent/ES2237764T3/es not_active Expired - Lifetime
- 1996-02-19 HU HU9800353A patent/HUP9800353A3/hu unknown
-
1998
- 1998-01-21 US US09/010,050 patent/US5880333A/en not_active Expired - Lifetime
-
1999
- 1999-01-20 US US09/234,190 patent/US6147282A/en not_active Expired - Lifetime
-
2001
- 2001-03-21 US US09/813,589 patent/US6939711B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6939711B2 (en) | 2005-09-06 |
JPH11500922A (ja) | 1999-01-26 |
HUP9800353A3 (en) | 2001-01-29 |
US6147282A (en) | 2000-11-14 |
CA2213340C (en) | 2011-07-26 |
AU4878296A (en) | 1996-09-23 |
WO1996027673A1 (en) | 1996-09-12 |
US20010022004A1 (en) | 2001-09-13 |
ATE293699T1 (de) | 2005-05-15 |
ES2237764T3 (es) | 2005-08-01 |
EP0813604B1 (de) | 2005-04-20 |
AU703124B2 (en) | 1999-03-18 |
DE69634630T2 (de) | 2005-11-10 |
CA2213340A1 (en) | 1996-09-12 |
US5880333A (en) | 1999-03-09 |
HUP9800353A2 (hu) | 1998-05-28 |
EP0813604A1 (de) | 1997-12-29 |
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