MXPA04002810A - Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos. - Google Patents

Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos.

Info

Publication number
MXPA04002810A
MXPA04002810A MXPA04002810A MXPA04002810A MXPA04002810A MX PA04002810 A MXPA04002810 A MX PA04002810A MX PA04002810 A MXPA04002810 A MX PA04002810A MX PA04002810 A MXPA04002810 A MX PA04002810A MX PA04002810 A MXPA04002810 A MX PA04002810A
Authority
MX
Mexico
Prior art keywords
ecdysone receptor
leafhopper ecdysone
polypeptides
nucleic acids
receptor nucleic
Prior art date
Application number
MXPA04002810A
Other languages
English (en)
Inventor
Reddy Palli Subba
Original Assignee
Rheogene Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rheogene Holdings Inc filed Critical Rheogene Holdings Inc
Publication of MXPA04002810A publication Critical patent/MXPA04002810A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Abstract

La presente invencion se refiere a un polipeptido receptor de ecdisona de saltarilla aislado novedoso. La invencion tambien se refiere a un acido nucleico aislado que codifica el polipeptido receptor de ecdisona de saltarilla, a vectores que lo comprenden y a sus usos, en particular en metodos para modular expresion de gen en un sistema para modulacion de expresion de gen basado en receptor de ecdisona y a metodos para identificar moleculas que modulan actividad de receptor de ecdisona de saltarilla.
MXPA04002810A 2001-09-26 2002-02-20 Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos. MXPA04002810A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32509601P 2001-09-26 2001-09-26
PCT/US2002/005026 WO2003027289A1 (en) 2001-09-26 2002-02-20 Leafhopper ecdysone receptor nucleic acids, polypeptides, and uses thereof

Publications (1)

Publication Number Publication Date
MXPA04002810A true MXPA04002810A (es) 2005-06-06

Family

ID=23266416

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04002810A MXPA04002810A (es) 2001-09-26 2002-02-20 Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos.

Country Status (6)

Country Link
US (4) US7563879B2 (es)
EP (1) EP1436394A4 (es)
JP (2) JP2005532781A (es)
CA (2) CA2459827C (es)
MX (1) MXPA04002810A (es)
WO (1) WO2003027289A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
US8105825B2 (en) * 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
WO2002066612A2 (en) 2001-02-20 2002-08-29 Rheogene, Inc. Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
CA2438119C (en) * 2001-02-20 2014-12-16 Rheogene Holdings, Inc. Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system
CA2441444C (en) 2001-02-20 2013-09-03 Rheogene Holdings, Inc. Novel ecdysone receptor/invertebrate retinoid x receptor-based inducible gene expression system
DK1534738T3 (da) 2001-02-20 2012-10-01 Intrexon Corp Nye substitutionsmutantreceptorer og anvendelse heraf i et inducérbart genekpressionssystem på basis af en nuklear receptor
DE10244149A1 (de) * 2001-09-25 2003-04-30 Werner Keber Verfahren und Einrichtung zum Verhindern einer unzulässigen Flugannäherung von Flugzeugen an zu schützende Bodenobjeke
MXPA04002810A (es) 2001-09-26 2005-06-06 Rheogene Holdings Inc Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos.
JP2005507247A (ja) * 2001-09-26 2005-03-17 レオジーン・ホールディングス，インコーポレーテッド コナジラミエクジソン受容体核酸、ポリペプチド、およびそれらの使用
US7304161B2 (en) 2003-02-10 2007-12-04 Intrexon Corporation Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
US7456315B2 (en) 2003-02-28 2008-11-25 Intrexon Corporation Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7935510B2 (en) * 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
US8115059B1 (en) 2005-07-22 2012-02-14 University Of Kentucky Research Foundation Gene expression modulation system for use in plants and method for modulating gene expression in plants
CN104761466A (zh) 2007-05-29 2015-07-08 英特拉克森公司 通过蜕皮素受体复合物调节外源性基因表达的手性二酰基肼配体
EP2205249B1 (en) 2007-09-28 2018-11-07 Intrexon Corporation Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
MX2010009996A (es) 2008-03-14 2010-10-20 Intrexon Corp Ligandos esteroides y su uso en la modulacion de genes interruptores.
TWI688395B (zh) 2010-03-23 2020-03-21 英翠克頌公司 條件性表現治療性蛋白質之載體、包含該載體之宿主細胞及彼等之用途
WO2012122025A2 (en) 2011-03-04 2012-09-13 Intrexon Corporation Vectors conditionally expressing protein
US8946294B2 (en) 2011-09-08 2015-02-03 Intrexon Corporation Crystalline diacylhydrazine and the use thereof
CN105283439B (zh) 2013-03-15 2018-02-02 英特瑞克斯顿股份有限公司 含硼的二酰基肼类化合物
CA2918452A1 (en) 2013-07-15 2015-01-22 Donald Danforth Plant Science Center Enhanced oil production and stress tolerance in plants
JP6567657B2 (ja) 2014-09-17 2019-08-28 イントレキソン コーポレーション ホウ素含有ジアシルヒドラジン化合物
WO2017062953A1 (en) 2015-10-10 2017-04-13 Intrexon Corporation Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
EP3387010A1 (en) 2015-11-11 2018-10-17 Intrexon Corporation Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies
WO2017214333A1 (en) 2016-06-08 2017-12-14 Intrexon Corporation Cd33 specific chimeric antigen receptors
UY37343A (es) 2016-07-25 2018-02-28 Intrexon Corp Control del fenotipo en plantas
NZ752941A (en) 2016-11-09 2023-04-28 Intrexon Corp Frataxin expression constructs
SG11201906213UA (en) 2017-01-10 2019-08-27 Intrexon Corp Modulating expression of polypeptides via new gene switch expression systems
IL270990B2 (en) 2017-06-07 2024-02-01 Precigen Inc Expression of new cell markers
CA3092935A1 (en) 2018-03-06 2019-09-12 Precigen, Inc. Hepatitis b vaccines and uses of the same
WO2020206056A1 (en) 2019-04-04 2020-10-08 Greenvenus Llc Peptides and methods of plant protection

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4985461A (en) * 1985-10-21 1991-01-15 Rohm And Haas Company Insecticidal N'-substituted-N,N'-diacylhydrazines
US5117057A (en) * 1985-10-21 1992-05-26 Rohm And Haas Company Insecticidal N' substituted-N-N'-disubstituted-hydrazines
US5424333A (en) * 1985-10-21 1995-06-13 Rohm And Haas Company Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines
FR2593630B1 (fr) 1986-01-27 1988-03-18 Maurice Francois Ecran d'affichage a matrice active a resistance de drain et procedes de fabrication de cet ecran
US4859609A (en) * 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5225443A (en) * 1986-05-01 1993-07-06 Rohm And Haas Company Insecticidal N'-substituted-N'-substituted N,N'-diacylhydrazines
US5071773A (en) * 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
US4981784A (en) * 1987-12-02 1991-01-01 The Salk Institute For Biological Studies Retinoic acid receptor method
US5171671A (en) * 1987-12-02 1992-12-15 The Salk Institute For Biological Studies Retinoic acid receptor composition
US5429952A (en) * 1988-02-02 1995-07-04 Biocode, Inc. Marking of products to establish identity and source
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
WO1989012690A1 (en) 1988-06-13 1989-12-28 American Biogentic Sciences, Inc. Method for the production of monoclonal antibodies utilizing a germfree animal
US4954655A (en) * 1989-03-31 1990-09-04 Rohm And Haas Company Preparation of alkylhydrazines
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
EP0514488B1 (en) * 1990-02-09 2000-09-13 The Salk Institute For Biological Studies Retinoid receptor compositions and methods
CA2076386C (en) * 1990-02-26 2003-04-22 David S. Hogness Identification and expression of insect steroid receptor dna sequence
US5688691A (en) * 1990-03-22 1997-11-18 The Salk Institute For Biological Studies Insect retinoid-like receptor compositions and methods
WO1991014695A1 (en) * 1990-03-22 1991-10-03 The Salk Institute For Biological Studies Insect retinoid receptor compositions and methods
US7119077B1 (en) * 1990-03-22 2006-10-10 The Salk Institute For Biological Studies Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
CA2043775A1 (en) 1990-06-14 1991-12-15 Dat P. Le Dibenzoylakylcyanohydrazines
US5139749A (en) 1990-06-22 1992-08-18 Tas, Inc. Fluidized calcining process
IL100643A (en) * 1991-01-25 1996-10-31 Nippon Kayaku Kk History of hydrazine and pesticides containing these histories as an active ingredient
WO1993003713A1 (en) * 1991-08-23 1993-03-04 The Salk Institute For Biological Studies Use of selective ligands for treatment of disease states responsive to steroid or steroid-like hormones
US5668175A (en) * 1991-08-23 1997-09-16 The Salk Institute For Biological Studies Use of selective ligands for treatment of disease states responsive to steroid or steroid-like retinoids
AU2579692A (en) * 1991-09-17 1993-04-27 Salk Institute For Biological Studies, The Receptor of the thyroid/steroid hormone receptor superfamily
JPH07503609A (ja) * 1991-12-06 1995-04-20 ザ　ソールク　インスチチュート　フォア　バイオロジカル　スタディズ リセプターのステロイド／甲状腺スーパーファミリーのメンバーの多量体型
JPH06510206A (ja) * 1992-01-24 1994-11-17 アンスティテュー・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル 新規ヘテロダイマー核レセプタータンパク質、それをコードする遺伝子、およびその使用
US5530028A (en) * 1992-11-23 1996-06-25 Rohm And Haas Company Insecticidal N'-substituted-N,N'-diacylhydrazines
US6013836A (en) * 1992-02-28 2000-01-11 Rohm And Haas Company Insecticidal N'-substituted-N,N'-disubstitutedhydrazines
JPH08501211A (ja) * 1992-07-02 1996-02-13 ザ ソールク インスチチュート フォア バイオロジカル スタディズ ウルトラスピラクル受容体とのマルチマー型ステロイド／甲状腺スーパーファミリー受容体メンバー
NZ267843A (en) 1993-05-27 1997-10-24 Selectide Corp Libraries of synthetic test compound attached to separate phase synthesis supports
WO1995013373A1 (en) * 1993-11-10 1995-05-18 Arch Development Corporation Ubiquitous nuclear receptor: compositions and methods
FR2714830B1 (fr) 1994-01-10 1996-03-22 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
FR2715847B1 (fr) 1994-02-08 1996-04-12 Rhone Poulenc Rorer Sa Composition contenant des acides nucléiques, préparation et utilisations.
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
FR2727679B1 (fr) 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
US6326166B1 (en) * 1995-12-29 2001-12-04 Massachusetts Institute Of Technology Chimeric DNA-binding proteins
EP0809509A4 (en) * 1995-01-13 2000-02-02 Salk Inst For Biological Studi ALLOSTERIC REGULATION OF NUCLEAR HORMONE RECEPTORS
FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
ES2237764T3 (es) * 1995-03-03 2005-08-01 Syngenta Participations Ag Control de la expresion genica en plantas por transactivacion mediada por un receptor en presencia de un ligando quimico.
AUPN174495A0 (en) * 1995-03-15 1995-04-06 Ketharanathan, Vettivetpillai Surgical prostheses
TR199701436T1 (xx) * 1995-05-26 1998-03-21 Zeneca Limited Bir ekdison resept�r�n� i�eren bir gen anahtar�.
US5939442A (en) * 1995-06-07 1999-08-17 The Salk Institute For Biological Studies Modulations of peroxisome proliferator activated receptor-γ, and methods for the use thereof
US6266622B1 (en) 1995-12-13 2001-07-24 Regents Of The University Of California Nuclear receptor ligands and ligand binding domains
GB9606126D0 (en) 1996-03-22 1996-05-22 British Biotech Pharm Biosensors
CA2200423C (en) 1996-03-26 2006-12-19 Sietse Mosselman Novel estrogen receptor
US6723531B2 (en) * 1996-04-05 2004-04-20 The Salk Institute For Biological Studies Method for modulating expression of exogenous genes in mammalian systems, and products related thereto
EP0910652B1 (en) 1996-04-05 2014-10-08 The Salk Institute For Biological Studies Hormone-mediated methods for modulating expression of exogenous genes in mammalian systems, and products related thereto
US6610828B1 (en) * 1996-05-24 2003-08-26 Syngenta Limited Heliothis ecdysone receptor
US6025483A (en) * 1996-06-05 2000-02-15 The Regents Of The University Of California Maize and cauliflower apetalai gene products and nucleic acid molecules encoding same
US5919667A (en) * 1996-06-20 1999-07-06 The Salk Institute For Biological Studies Modular assembly retroviral vectors and uses thereof
US5942444A (en) 1997-01-27 1999-08-24 Biocode, Inc. Marking of products to establish identity, source and fate
FR2759084B1 (fr) * 1997-02-06 1999-10-29 Dev Des Utilisations Du Collag Materiau collagenique utile notamment pour la prevention d'adherences post-operatoires
WO1998035550A2 (en) 1997-02-14 1998-08-20 New Zealand Pastoral Agriculture Research Institute Limited Insect ecdysteroid receptors
WO1999002683A1 (en) 1997-07-10 1999-01-21 The Salk Institute For Biological Studies Modified lepidopteran receptors and hybrid multifunctional proteins for use in regulation of transgene expression
US6300488B1 (en) * 1997-07-10 2001-10-09 The Salk Institute For Biological Studies Modified lepidopteran receptors and hybrid multifunctional proteins for use in transcription and regulation of transgene expression
EP1017829A2 (en) 1997-08-26 2000-07-12 Ariad Gene Therapeutics, Inc. Fusion proteins comprising a dimerization, trimerization or tetramerization domain and an additional heterologous transcription activation, transcription repression, dna binding or ligand binding domain
US6576019B1 (en) * 1997-10-31 2003-06-10 Children's Medical Center Corporation Bladder reconstruction
IT1297070B1 (it) 1997-11-21 1999-08-03 Micronasa Di Patarchi Alberto Macchina dinamoelettrica rotante a induzione elettromagnetica come agente in motori elettrici lineari.
US7101681B1 (en) 1997-11-21 2006-09-05 Amgen, Inc. Nuclear hormone receptor drug screens
US6756491B2 (en) * 1998-01-09 2004-06-29 The Salk Institute For Biological Studies Steroid-activated nuclear receptors and uses therefor
AUPP135698A0 (en) * 1998-01-15 1998-02-05 Commonwealth Scientific And Industrial Research Organisation Insectical modalities
US6410245B1 (en) * 1998-04-01 2002-06-25 Affymax, Inc. Compositions and methods for detecting ligand-dependent nuclear receptor and coactivator interactions
US6475733B1 (en) 1998-04-06 2002-11-05 Lerner Pharmaceuticals, Inc. Cell surface receptors for the detection and identification of compounds
US6333318B1 (en) * 1998-05-14 2001-12-25 The Salk Institute For Biological Studies Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
US6258603B1 (en) 1998-06-17 2001-07-10 Rohm And Haas Company Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US6117639A (en) * 1998-08-31 2000-09-12 Vertex Pharmaceuticals Incorporated Fusion proteins, DNA molecules, vectors, and host cells useful for measuring protease activity
JP2002525053A (ja) * 1998-09-10 2002-08-13 パイオニア ハイ−ブレッド インターナショナル， インコーポレイテッド エクジソンレセプターおよびそれらの使用のための方法
FR2783429B1 (fr) * 1998-09-18 2002-04-12 Imedex Biomateriaux Materiau collagenique bicomposite,son procede d'obtention et ses applications therapeutiques
US20030225355A1 (en) * 1998-10-01 2003-12-04 Butler Charles E. Composite material for wound repair
US5989863A (en) * 1998-10-14 1999-11-23 Incyte Pharmaceuticals, Inc. Human ankyrin family protein
WO2000071743A1 (fr) 1999-05-25 2000-11-30 Eisai Co., Ltd. Methode bihybride dans une cellule de mammifere
JP2003505019A (ja) 1999-07-01 2003-02-12 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼーション ステロイドおよび幼若ホルモン受容体ポリペプチドをコードする新規遺伝子配列ならびにその用途
US7057015B1 (en) * 1999-10-20 2006-06-06 The Salk Institute For Biological Studies Hormone receptor functional dimers and methods of their use
AU2001241682A1 (en) 2000-02-24 2001-09-03 The Salk Institute For Biological Studies Gene expression system based on chimeric receptors
US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
CA2404253C (en) * 2000-03-22 2014-05-13 Rohm And Haas Company Novel ecdysone receptor-based inducible gene expression system
US6974679B2 (en) * 2000-05-26 2005-12-13 Coletica Support with collagen base for tissue engineering and manufacture of biomaterials
US6790454B1 (en) * 2000-05-26 2004-09-14 Coletica Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained
US7011972B2 (en) * 2000-07-18 2006-03-14 The Scripps Research Institute Fusion polypeptide comprising two ligand binding domains
US8105825B2 (en) * 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
WO2002061102A2 (en) * 2000-10-24 2002-08-08 Syngenta Participations Ag Control of gene expression in plants
DK1534738T3 (da) * 2001-02-20 2012-10-01 Intrexon Corp Nye substitutionsmutantreceptorer og anvendelse heraf i et inducérbart genekpressionssystem på basis af en nuklear receptor
CA2441444C (en) 2001-02-20 2013-09-03 Rheogene Holdings, Inc. Novel ecdysone receptor/invertebrate retinoid x receptor-based inducible gene expression system
CA2438119C (en) * 2001-02-20 2014-12-16 Rheogene Holdings, Inc. Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system
WO2002066612A2 (en) * 2001-02-20 2002-08-29 Rheogene, Inc. Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
CN1161325C (zh) 2001-03-26 2004-08-11 江苏省农药研究所 作为杀虫剂的二酰基肼类化合物及制备此种化合物的中间体以及它们的制备方法
JP2005507247A (ja) 2001-09-26 2005-03-17 レオジーン・ホールディングス，インコーポレーテッド コナジラミエクジソン受容体核酸、ポリペプチド、およびそれらの使用
MXPA04002810A (es) 2001-09-26 2005-06-06 Rheogene Holdings Inc Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos.
US20050228016A1 (en) 2002-06-13 2005-10-13 Enrique Michelotti Tetrahydroquinolines for modulating the expression of exogenous genes via an ecdysone receptor complex
US7375093B2 (en) 2002-07-05 2008-05-20 Intrexon Corporation Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7304161B2 (en) 2003-02-10 2007-12-04 Intrexon Corporation Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
US7304162B2 (en) 2003-02-21 2007-12-04 Intrexon Corporation Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7456315B2 (en) * 2003-02-28 2008-11-25 Intrexon Corporation Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
US7935510B2 (en) * 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
US9034650B2 (en) 2005-02-02 2015-05-19 Intrexon Corporation Site-specific serine recombinases and methods of their use
CA2713303A1 (en) * 2007-02-26 2008-09-04 John Wayne Cancer Institute Utility of b-raf dna mutation in diagnosis and treatment of cancer
US8497092B2 (en) * 2008-04-03 2013-07-30 Tsumura & Co. Method of bioassaying yokukansan

Also Published As

Publication number Publication date
US20080280321A9 (en) 2008-11-13
US7563879B2 (en) 2009-07-21
US8021878B2 (en) 2011-09-20
WO2003027289A1 (en) 2003-04-03
US8497093B2 (en) 2013-07-30
US20040197861A1 (en) 2004-10-07
CA2820144A1 (en) 2003-04-03
EP1436394A1 (en) 2004-07-14
US20120115233A1 (en) 2012-05-10
US8680249B2 (en) 2014-03-25
EP1436394A4 (en) 2004-12-29
CA2459827A1 (en) 2003-04-03
US20080214790A1 (en) 2008-09-04
JP2005532781A (ja) 2005-11-04
US20080064097A1 (en) 2008-03-13
JP2009159958A (ja) 2009-07-23
CA2820144C (en) 2017-06-20
CA2459827C (en) 2013-09-03

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