CN103261201B - 作为trpa1拮抗剂的2-氨基-4-芳基噻唑化合物 - Google Patents

作为trpa1拮抗剂的2-氨基-4-芳基噻唑化合物 Download PDF

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CN103261201B
CN103261201B CN201180059690.2A CN201180059690A CN103261201B CN 103261201 B CN103261201 B CN 103261201B CN 201180059690 A CN201180059690 A CN 201180059690A CN 103261201 B CN103261201 B CN 103261201B
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dioxo
thiazol
pyrimidin
phenyl
trifluoromethyl
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CN103261201A (zh
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苏克尔斯·库马尔
亚伯拉罕·托马斯
萨钦·孙达尔拉·乔德阿里
拜平·帕斯塔姆·康萨吉亚
文卡塔·拉玛纳·耶米内迪
尼利马·坎拉特卡-乔希
因德拉尼尔·穆霍帕拉艾
吉雷斯·居迪
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Ichnos Sciences SA
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Glenmark Pharmaceuticals SA
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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CN201180059690.2A 2010-12-20 2011-12-15 作为trpa1拮抗剂的2-氨基-4-芳基噻唑化合物 Expired - Fee Related CN103261201B (zh)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
IN3451MU2010 2010-12-20
IN3451/MUM/2010 2010-12-20
US201061428327P 2010-12-30 2010-12-30
US61/428,327 2010-12-30
IN748/MUM/2011 2011-03-16
IN748MU2011 2011-03-16
US201161466535P 2011-03-23 2011-03-23
US61/466,535 2011-03-23
IN1569/MUM/2011 2011-05-25
IN1569MU2011 2011-05-25
US201161495002P 2011-06-09 2011-06-09
US61/495,002 2011-06-09
IN2741MU2011 2011-09-28
IN2741/MUM/2011 2011-09-28
US201161552076P 2011-10-27 2011-10-27
US61/552,076 2011-10-27
PCT/IB2011/003224 WO2012085662A1 (en) 2010-12-20 2011-12-15 2-amino-4-arylthiazole compounds as trpa1 antagonists

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CN103261201A CN103261201A (zh) 2013-08-21
CN103261201B true CN103261201B (zh) 2015-04-22

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US (3) US8592398B2 (ru)
EP (1) EP2655377B1 (ru)
JP (1) JP5694560B2 (ru)
KR (1) KR101591153B1 (ru)
CN (1) CN103261201B (ru)
AP (1) AP3391A (ru)
AR (1) AR084294A1 (ru)
AU (1) AU2011346763B2 (ru)
BR (1) BR112013014692A2 (ru)
CA (1) CA2820448A1 (ru)
CL (1) CL2013001810A1 (ru)
EA (1) EA023141B1 (ru)
HK (1) HK1191008A1 (ru)
MX (1) MX336549B (ru)
MY (1) MY159059A (ru)
PE (1) PE20140234A1 (ru)
SG (1) SG191173A1 (ru)
TW (1) TWI515199B (ru)
UA (1) UA109916C2 (ru)
WO (1) WO2012085662A1 (ru)

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CN104350058A (zh) 2012-06-08 2015-02-11 格兰马克药品股份有限公司 2-氨基-4-芳基噻唑化合物的酰胺及其盐
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CN108727400B (zh) * 2017-05-24 2021-07-09 四川晶华生物科技有限公司 一种治疗肿瘤的化合物
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BR112021007692A2 (pt) * 2018-10-23 2021-08-10 George Edward Hoag composição e método para tratar os pulmões
EP4045144A1 (en) * 2019-10-15 2022-08-24 Boehringer Ingelheim International Gmbh Thienopyrimidones as trpa1 inhibitors
CN114929712B (zh) * 2019-10-15 2024-07-23 勃林格殷格翰国际有限公司 作为trpa1抑制剂的噻吩并嘧啶酮
IL297555A (en) * 2020-04-22 2022-12-01 George Edward Hoag A method of treating a viral or bacterial infection using inhalation therapy
CN111437275B (zh) * 2020-05-14 2021-03-19 黑龙江中医药大学 一种用于外科手术后抗炎和镇痛的药物及其应用

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