CN103097418A - 抗神经毡蛋白抗体及使用方法 - Google Patents

抗神经毡蛋白抗体及使用方法 Download PDF

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Publication number
CN103097418A
CN103097418A CN2011800433017A CN201180043301A CN103097418A CN 103097418 A CN103097418 A CN 103097418A CN 2011800433017 A CN2011800433017 A CN 2011800433017A CN 201180043301 A CN201180043301 A CN 201180043301A CN 103097418 A CN103097418 A CN 103097418A
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CN
China
Prior art keywords
antibody
amino acid
nrp1
antibodies
seq
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CN2011800433017A
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English (en)
Chinese (zh)
Inventor
M.施米特
C.卡拉汉
J-A.S.宏戈
H.科彭
R.J.沃茨
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2011800433017A 2010-07-09 2011-07-08 抗神经毡蛋白抗体及使用方法 Pending CN103097418A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36312110P 2010-07-09 2010-07-09
US61/363,121 2010-07-09
PCT/US2011/043318 WO2012006503A1 (en) 2010-07-09 2011-07-08 Anti-neuropilin antibodies and methods of use

Publications (1)

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CN103097418A true CN103097418A (zh) 2013-05-08

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CN2011800433017A Pending CN103097418A (zh) 2010-07-09 2011-07-08 抗神经毡蛋白抗体及使用方法

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US (1) US8993249B2 (enExample)
EP (1) EP2591004A1 (enExample)
JP (1) JP2013539962A (enExample)
KR (1) KR20130120439A (enExample)
CN (1) CN103097418A (enExample)
AU (1) AU2011274528B2 (enExample)
BR (1) BR112013000340A2 (enExample)
CA (1) CA2803792A1 (enExample)
MX (1) MX2013000083A (enExample)
NZ (1) NZ605449A (enExample)
RU (1) RU2571226C2 (enExample)
SG (1) SG186983A1 (enExample)
WO (1) WO2012006503A1 (enExample)
ZA (1) ZA201300174B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105237637A (zh) * 2015-11-10 2016-01-13 厦门大学 抗人神经纤毛蛋白1的单域抗体及其制备方法

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EP3677310A1 (en) * 2012-10-08 2020-07-08 St. Jude Children's Research Hospital Therapies based on control of regulatory t cell stability and function via a neuropilin-1:semaphorin axis
EP3241844B1 (en) * 2014-12-03 2021-04-21 Aimed Bio Inc. Antibody against neuropilin 1 and use thereof
DK3417073T3 (da) 2016-02-19 2023-10-30 Procella Therapeutics Ab Genetiske markører til transplantation af humane, hjerteventrikulære progenitorceller
KR101985299B1 (ko) * 2016-06-03 2019-09-03 삼성전자주식회사 항-c-Met/항-Nrp1 이중 특이 항체
US10508263B2 (en) 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells
JOP20190134A1 (ar) 2016-12-23 2019-06-02 Potenza Therapeutics Inc بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
JP7275109B2 (ja) * 2017-08-23 2023-05-17 プロセラ セラピューティクス アーベー ニューロピリン－１（ｎｒｐ１）のヒト心室前駆細胞を単離するための細胞表面マーカーとしての使用
JP2024508207A (ja) 2020-12-02 2024-02-26 ブイアイビー ブイゼットダブリュ がんに対する組み合わせ治療におけるｌｔｂｒアゴニスト

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101326196A (zh) * 2005-11-08 2008-12-17 健泰科生物技术公司 神经纤毛蛋白拮抗剂

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Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN105237637A (zh) * 2015-11-10 2016-01-13 厦门大学 抗人神经纤毛蛋白1的单域抗体及其制备方法
CN105237637B (zh) * 2015-11-10 2018-10-30 厦门大学 抗人神经纤毛蛋白1的单域抗体及其制备方法

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RU2571226C2 (ru) 2015-12-20
AU2011274528A1 (en) 2013-01-24
EP2591004A1 (en) 2013-05-15
MX2013000083A (es) 2013-02-26
US8993249B2 (en) 2015-03-31
CA2803792A1 (en) 2012-01-12
RU2013105487A (ru) 2014-08-20
SG186983A1 (en) 2013-02-28
ZA201300174B (en) 2014-03-26
NZ605449A (en) 2015-03-27
AU2011274528B2 (en) 2015-04-23
US20130115626A1 (en) 2013-05-09
BR112013000340A2 (pt) 2016-05-31
KR20130120439A (ko) 2013-11-04
WO2012006503A1 (en) 2012-01-12
JP2013539962A (ja) 2013-10-31

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