CN102741410B - Hsp47表达的调节 - Google Patents
Hsp47表达的调节 Download PDFInfo
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- CN102741410B CN102741410B CN201080060946.7A CN201080060946A CN102741410B CN 102741410 B CN102741410 B CN 102741410B CN 201080060946 A CN201080060946 A CN 201080060946A CN 102741410 B CN102741410 B CN 102741410B
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610933224.7A CN106701758B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
| CN201610933223.2A CN106701757B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28514909P | 2009-12-09 | 2009-12-09 | |
| US61/285,149 | 2009-12-09 | ||
| US30741210P | 2010-02-23 | 2010-02-23 | |
| US61/307,412 | 2010-02-23 | ||
| US37207210P | 2010-08-09 | 2010-08-09 | |
| US61/372,072 | 2010-08-09 | ||
| PCT/US2010/059578 WO2011072082A2 (en) | 2009-12-09 | 2010-12-08 | Modulation of hsp47 expression |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610933223.2A Division CN106701757B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
| CN201610933224.7A Division CN106701758B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102741410A CN102741410A (zh) | 2012-10-17 |
| CN102741410B true CN102741410B (zh) | 2016-11-16 |
Family
ID=44146170
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610933223.2A Active CN106701757B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
| CN201080060946.7A Active CN102741410B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
| CN201610933224.7A Active CN106701758B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610933223.2A Active CN106701757B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610933224.7A Active CN106701758B (zh) | 2009-12-09 | 2010-12-08 | Hsp47表达的调节 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8710209B2 (enExample) |
| EP (3) | EP2509991B1 (enExample) |
| JP (3) | JP5685267B2 (enExample) |
| KR (3) | KR101900588B1 (enExample) |
| CN (3) | CN106701757B (enExample) |
| AU (1) | AU2010328104B2 (enExample) |
| CA (1) | CA2781896C (enExample) |
| DK (1) | DK2509991T3 (enExample) |
| ES (1) | ES2562499T3 (enExample) |
| IL (2) | IL219804A (enExample) |
| PL (1) | PL2509991T3 (enExample) |
| PT (1) | PT2509991E (enExample) |
| TW (3) | TWI611021B (enExample) |
| WO (1) | WO2011072082A2 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009221164A (ja) | 2008-03-17 | 2009-10-01 | Nitto Denko Corp | 肺線維症処置剤 |
| US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| EP2504435B1 (en) | 2009-11-26 | 2019-11-13 | Quark Pharmaceuticals, Inc. | Sirna compounds comprising terminal substitutions |
| WO2011084193A1 (en) | 2010-01-07 | 2011-07-14 | Quark Pharmaceuticals, Inc. | Oligonucleotide compounds comprising non-nucleotide overhangs |
| RU2711531C2 (ru) * | 2010-06-17 | 2020-01-17 | Нитто Денко Корпорейшн | Средство для лечения фиброза почек |
| JP5950428B2 (ja) | 2010-08-05 | 2016-07-13 | 日東電工株式会社 | 線維化組織から正常組織を再生するための組成物 |
| ES2664992T3 (es) | 2010-12-02 | 2018-04-24 | Daiichi Sankyo Company, Limited | Polinucleótido monocatenario modificado |
| TWI658830B (zh) | 2011-06-08 | 2019-05-11 | 日東電工股份有限公司 | Hsp47表現調控強化用類視色素脂質體 |
| US10196637B2 (en) | 2011-06-08 | 2019-02-05 | Nitto Denko Corporation | Retinoid-lipid drug carrier |
| EP2739637A4 (en) * | 2011-08-03 | 2015-04-22 | Quark Pharmaceuticals Inc | DOUBLE-STRONG OLIGONUCLEOTIDE COMPOUNDS FOR THE TREATMENT OF HEARING AND BALANCE OF IMPAIRMENT |
| TWI627965B (zh) * | 2011-11-18 | 2018-07-01 | 日東電工股份有限公司 | 腸道纖維化處置劑 |
| FI3366775T4 (fi) | 2011-11-18 | 2025-11-14 | Alnylam Pharmaceuticals Inc | Modifioituja rnai-agensseja |
| CA2895077A1 (en) * | 2011-12-12 | 2013-06-20 | Beverly Packard | In vivo delivery of oligonucleotides |
| CA2858630A1 (en) | 2012-01-12 | 2013-07-18 | Quark Pharmaceuticals, Inc. | Combination therapy for treating hearing and balance disorders |
| US10260089B2 (en) | 2012-10-29 | 2019-04-16 | The Research Foundation Of The State University Of New York | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids |
| JP6340162B2 (ja) | 2012-12-20 | 2018-06-06 | 日東電工株式会社 | アポトーシス誘導剤 |
| JP7011389B2 (ja) * | 2013-06-12 | 2022-01-26 | オンコイミューニン,インコーポレイティド | オリゴヌクレオチドの全身性イン-ビボ送達 |
| WO2015051366A2 (en) * | 2013-10-04 | 2015-04-09 | Novartis Ag | Novel formats for organic compounds for use in rna interference |
| JP6694811B2 (ja) * | 2013-10-04 | 2020-05-20 | ノバルティス アーゲー | RNA干渉に使用するためのRNAi剤用の3’末端キャップ |
| JP6602034B2 (ja) | 2014-04-02 | 2019-11-06 | 日東電工株式会社 | 標的化分子およびその使用 |
| WO2015155810A1 (en) | 2014-04-07 | 2015-10-15 | Nitto Denko Corporation | Novel polymer-based hydrotropes for hydrophobic drug delivery |
| WO2016097212A1 (en) | 2014-12-17 | 2016-06-23 | Proqr Therapeutics Ii B.V. | Targeted rna editing |
| US20180002702A1 (en) | 2014-12-26 | 2018-01-04 | Nitto Denko Corporation | Methods and compositions for treating malignant tumors associated with kras mutation |
| US11045488B2 (en) | 2014-12-26 | 2021-06-29 | Nitto Denko Corporation | RNA interference agents for GST-π gene modulation |
| US10264976B2 (en) | 2014-12-26 | 2019-04-23 | The University Of Akron | Biocompatible flavonoid compounds for organelle and cell imaging |
| US10792299B2 (en) | 2014-12-26 | 2020-10-06 | Nitto Denko Corporation | Methods and compositions for treating malignant tumors associated with kras mutation |
| KR102740699B1 (ko) | 2015-12-13 | 2024-12-09 | 닛토덴코 가부시키가이샤 | 높은 활성 및 감소한 오프 타겟을 위한 sirna 구조 |
| CN109477103A (zh) | 2016-06-22 | 2019-03-15 | ProQR治疗上市公司Ⅱ | 单链rna-编辑寡核苷酸 |
| ES2837076T3 (es) | 2016-09-01 | 2021-06-29 | Proqr Therapeutics Ii Bv | Oligonucleótidos para la edición de ARN de cadena sencilla modificados químicamente |
| JP6833456B2 (ja) | 2016-11-02 | 2021-02-24 | 日東電工株式会社 | 皮膚線維症処置剤 |
| AU2017368050A1 (en) | 2016-11-29 | 2019-06-20 | Puretech Lyt, Inc. | Exosomes for delivery of therapeutic agents |
| WO2018134301A1 (en) * | 2017-01-19 | 2018-07-26 | Proqr Therapeutics Ii B.V. | Oligonucleotide complexes for use in rna editing |
| GB201808146D0 (en) | 2018-05-18 | 2018-07-11 | Proqr Therapeutics Ii Bv | Stereospecific Linkages in RNA Editing Oligonucleotides |
| CN114401769A (zh) * | 2019-03-27 | 2022-04-26 | 菲尼克斯组织修复公司 | 生产胶原蛋白7组合物的系统和方法 |
| CN110237235B (zh) * | 2019-06-04 | 2023-03-28 | 徐州医科大学 | 华支睾吸虫重组蛋白CsHscB在胆汁淤积性肝纤维化治疗药物中的应用 |
| CN111135300A (zh) * | 2020-01-09 | 2020-05-12 | 南京大学 | 一种蛋白抑制剂在制备减轻雾霾引起肺炎的药物中的用途 |
| CA3171367A1 (en) * | 2020-03-11 | 2021-09-16 | Zhi-Ren Liu | Methods for treating fibrosis using pkm2 activators |
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| JPWO2022154123A1 (enExample) * | 2021-01-15 | 2022-07-21 | ||
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