CN102209556B - 改良的抗cd19抗体 - Google Patents

改良的抗cd19抗体 Download PDF

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Publication number
CN102209556B
CN102209556B CN200980144442.0A CN200980144442A CN102209556B CN 102209556 B CN102209556 B CN 102209556B CN 200980144442 A CN200980144442 A CN 200980144442A CN 102209556 B CN102209556 B CN 102209556B
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antibody
antigen
antibodies
binding fragment
cell
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CN102209556A (zh
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H·J·汉森
Z·屈
D·M·古德伯格
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Immunomedics Inc
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Immunomedics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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CN200980144442.0A 2008-11-07 2009-10-22 改良的抗cd19抗体 Active CN102209556B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/266,999 2008-11-07
US12/266,999 US7902338B2 (en) 2003-07-31 2008-11-07 Anti-CD19 antibodies
PCT/US2009/061666 WO2010053716A1 (en) 2008-11-07 2009-10-22 Improved anti-cd19 antibodies

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CN102209556A CN102209556A (zh) 2011-10-05
CN102209556B true CN102209556B (zh) 2018-02-23

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US (9) US7902338B2 (enExample)
EP (1) EP2352523B1 (enExample)
JP (3) JP5762965B2 (enExample)
CN (1) CN102209556B (enExample)
AU (1) AU2009311461B2 (enExample)
CA (1) CA2742254A1 (enExample)
IL (1) IL212701A (enExample)
WO (1) WO2010053716A1 (enExample)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8420086B2 (en) 2002-12-13 2013-04-16 Immunomedics, Inc. Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
US7902338B2 (en) * 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
US8034352B2 (en) * 2005-04-06 2011-10-11 Ibc Pharmaceuticals, Inc. Tetrameric cytokines with improved biological activity
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