CN102202673B - 包含双醋瑞因的药物组合物 - Google Patents

包含双醋瑞因的药物组合物 Download PDF

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Publication number
CN102202673B
CN102202673B CN2009801431098A CN200980143109A CN102202673B CN 102202673 B CN102202673 B CN 102202673B CN 2009801431098 A CN2009801431098 A CN 2009801431098A CN 200980143109 A CN200980143109 A CN 200980143109A CN 102202673 B CN102202673 B CN 102202673B
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China
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composite
weight
diacerein
controlled release
release composite
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Expired - Fee Related
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CN2009801431098A
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Chinese (zh)
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CN102202673A (zh
Inventor
高丹晨
吴振森
卢威书
陈守琼
郭姵君
陈志明
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TWi Biotechnology Inc
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TWi Biotechnology Inc
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2009801431098A 2008-10-28 2009-10-28 包含双醋瑞因的药物组合物 Expired - Fee Related CN102202673B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10893108P 2008-10-28 2008-10-28
US61/108,931 2008-10-28
PCT/US2009/062302 WO2010051296A1 (en) 2008-10-28 2009-10-28 Pharmaceutical compositions containing diacerein

Publications (2)

Publication Number Publication Date
CN102202673A CN102202673A (zh) 2011-09-28
CN102202673B true CN102202673B (zh) 2013-07-31

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CN2009801431098A Expired - Fee Related CN102202673B (zh) 2008-10-28 2009-10-28 包含双醋瑞因的药物组合物

Country Status (19)

Country Link
US (2) US20100104651A1 (https=)
EP (1) EP2349289B1 (https=)
JP (1) JP5642691B2 (https=)
KR (1) KR101718347B1 (https=)
CN (1) CN102202673B (https=)
AR (1) AR073918A1 (https=)
AU (1) AU2009308958B2 (https=)
BR (1) BRPI0920255A2 (https=)
CA (1) CA2741846C (https=)
ES (1) ES2585904T3 (https=)
IL (1) IL212483A (https=)
MX (1) MX2011004395A (https=)
NZ (1) NZ592376A (https=)
PA (1) PA8846801A1 (https=)
RU (1) RU2542461C2 (https=)
SA (1) SA109300644B1 (https=)
TW (1) TWI473610B (https=)
UY (1) UY32204A (https=)
WO (1) WO2010051296A1 (https=)

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KR101567925B1 (ko) * 2010-04-08 2015-11-10 티더블유아이 바이오테크놀로지 인코포레이티드 당뇨병 보조치료요법으로서 디아세레인을 사용하는 방법
CN101822660B (zh) * 2010-05-13 2013-07-10 中国人民解放军肾脏病研究所 大黄酸类化合物或其盐在制备预防和治疗胰岛β细胞功能衰退药物中的应用
CN103429236B (zh) * 2011-03-11 2016-09-21 安成生物科技股份有限公司 治疗高尿酸血症和与高尿酸血症相关的代谢性病症的方法和组合物
CN102743370B (zh) * 2011-06-27 2013-05-15 王子厚 双醋瑞因的用途
JP6224597B2 (ja) * 2011-09-27 2017-11-01 バイオメッド バレー ディスカバリーズ，インコーポレイティド グリオーマを処置するための組成物及び方法
EA201491039A1 (ru) * 2011-12-27 2015-02-27 Сановел Илач Санайи Ве Тиджарет Аноним Ширкети Комбинации диацереина и нестероидных противовоспалительных лекарственных средств
WO2013100881A2 (en) * 2011-12-27 2013-07-04 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Combined pharmaceutical formulation containing diacerein
CN102871982B (zh) * 2012-10-16 2014-09-10 中国科学院上海药物研究所 一种药物渗透泵制剂
US11198724B2 (en) 2013-03-14 2021-12-14 The Regents Of The University Of Michigan Treatment of staphylococcal disorders
CN107708681A (zh) * 2015-04-20 2018-02-16 安成生物科技股份有限公司 含有双醋瑞因的制剂及使用其降低尿酸血液水平的方法
MX373702B (es) * 2015-07-01 2020-05-07 Twi Biotechnology Inc Formulaciones topicas de diacereina o rheina y sus usos.
US10154984B2 (en) * 2015-07-01 2018-12-18 Twi Biotechnology, Inc. Diacerein or Rhein topical formulations and uses thereof
US10512625B2 (en) * 2015-07-01 2019-12-24 Twi Biotechnology, Inc. Diacerein or rhein topical formulations and uses thereof
US10195170B2 (en) * 2015-08-17 2019-02-05 Twi Biotechnology, Inc. Methods for inhibiting expression of ASC, expression of NLRP3, and/or formation of NLRP3 inflammasome complex using diacerein or its analogs
CN110177547B (zh) * 2017-01-18 2022-09-27 台睿生物科技股份有限公司 用于治疗炎症性肠病和肠结肠炎的组合物
JP2020505362A (ja) 2017-01-19 2020-02-20 ティダブリューアイ・バイオテクノロジー・インコーポレイテッドＴＷＩ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， Ｉｎｃ． 免疫炎症性皮膚障害を予防または治療するための方法および医薬組成物
EP3459528B1 (en) * 2017-09-20 2022-11-23 Tillotts Pharma Ag Preparation of solid dosage forms comprising antibodies by solution/suspension layering
CN107929264B (zh) * 2017-12-04 2020-04-24 广东药科大学 双醋瑞因缓释微球及其制备方法
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