CN101970435B - 吡咯并嘧啶和吡咯并吡啶类化合物 - Google Patents

吡咯并嘧啶和吡咯并吡啶类化合物 Download PDF

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Publication number
CN101970435B
CN101970435B CN200980108446.3A CN200980108446A CN101970435B CN 101970435 B CN101970435 B CN 101970435B CN 200980108446 A CN200980108446 A CN 200980108446A CN 101970435 B CN101970435 B CN 101970435B
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pyridin
methyl
pyridine
pyrrolo
phenyl
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CN101970435A (zh
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C·勒布朗
R·A·普尔兹
N·J·施蒂夫尔
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Novartis AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Rheumatology (AREA)
  • Cardiology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
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  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN200980108446.3A 2008-01-11 2009-01-09 吡咯并嘧啶和吡咯并吡啶类化合物 Expired - Fee Related CN101970435B (zh)

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Application Number Priority Date Filing Date Title
EP08150182 2008-01-11
EP08150182.7 2008-01-11
PCT/EP2009/050225 WO2009087225A2 (en) 2008-01-11 2009-01-09 Pyrrolopyrimidines and pyrrolopyridines

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CN101970435A CN101970435A (zh) 2011-02-09
CN101970435B true CN101970435B (zh) 2014-07-02

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US (1) US8314112B2 (enExample)
EP (1) EP2242756A2 (enExample)
JP (1) JP5643110B2 (enExample)
KR (1) KR20100116606A (enExample)
CN (1) CN101970435B (enExample)
AR (1) AR070127A1 (enExample)
AU (1) AU2009203694B2 (enExample)
BR (1) BRPI0907231A2 (enExample)
CA (1) CA2711845A1 (enExample)
CL (1) CL2009000028A1 (enExample)
CO (1) CO6331340A2 (enExample)
CR (1) CR11554A (enExample)
EA (1) EA201001126A1 (enExample)
EC (1) ECSP10010335A (enExample)
IL (1) IL206819A0 (enExample)
MA (1) MA31952B1 (enExample)
MX (1) MX2010007605A (enExample)
PE (1) PE20091306A1 (enExample)
TN (1) TN2010000305A1 (enExample)
TW (1) TW200934781A (enExample)
WO (1) WO2009087225A2 (enExample)
ZA (1) ZA201004602B (enExample)

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KR20100116606A (ko) 2010-11-01
AU2009203694B2 (en) 2012-04-26
EP2242756A2 (en) 2010-10-27
AU2009203694A1 (en) 2009-07-16
US20090181941A1 (en) 2009-07-16
AR070127A1 (es) 2010-03-17
EA201001126A1 (ru) 2011-02-28
CO6331340A2 (es) 2011-10-20
MA31952B1 (fr) 2010-12-01
WO2009087225A3 (en) 2009-11-05
CL2009000028A1 (es) 2009-07-17
PE20091306A1 (es) 2009-09-24
JP2011509279A (ja) 2011-03-24
TW200934781A (en) 2009-08-16
CA2711845A1 (en) 2009-07-16
IL206819A0 (en) 2010-12-30
MX2010007605A (es) 2010-08-02
WO2009087225A2 (en) 2009-07-16
BRPI0907231A2 (pt) 2019-09-24
US8314112B2 (en) 2012-11-20
JP5643110B2 (ja) 2014-12-17
TN2010000305A1 (en) 2011-11-11
CN101970435A (zh) 2011-02-09
CR11554A (es) 2010-08-11
ECSP10010335A (es) 2010-08-31

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