CL2009000028A1 - Compuestos heterocíclicos derivados de 1h-pirrolo[2,3-b]piridina y 7h-pirrolo[2,3-b]pirimidina sustituidos; procedimiento de preparación de los compuestos; composición farmacéutica; su uso en el tratamiento de condiciones óseas asociadas con la resorción de calcio, útiles en el tratamiento de la hipertensión pulmonar, artritis, entre otras. - Google Patents
Compuestos heterocíclicos derivados de 1h-pirrolo[2,3-b]piridina y 7h-pirrolo[2,3-b]pirimidina sustituidos; procedimiento de preparación de los compuestos; composición farmacéutica; su uso en el tratamiento de condiciones óseas asociadas con la resorción de calcio, útiles en el tratamiento de la hipertensión pulmonar, artritis, entre otras.Info
- Publication number
- CL2009000028A1 CL2009000028A1 CL2009000028A CL2009000028A CL2009000028A1 CL 2009000028 A1 CL2009000028 A1 CL 2009000028A1 CL 2009000028 A CL2009000028 A CL 2009000028A CL 2009000028 A CL2009000028 A CL 2009000028A CL 2009000028 A1 CL2009000028 A1 CL 2009000028A1
- Authority
- CL
- Chile
- Prior art keywords
- pyrrolo
- treatment
- pharmaceutical composition
- conditions associated
- pulmonary hypertension
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Compuestos derivados de pirrolo-pirimidinas y pirrolo-piridinas; procedimiento de preparación; composición farmacéutica; y uso del compuesto para el tratamiento de condiciones óseas asociadas al agotamiento o resorción de calcio, hipertensión pulmonar y enfermedad renal, Alzheimer, osteoporosis, entre otros.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08150182 | 2008-01-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2009000028A1 true CL2009000028A1 (es) | 2009-07-17 |
Family
ID=39445770
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2009000028A CL2009000028A1 (es) | 2008-01-11 | 2009-01-09 | Compuestos heterocíclicos derivados de 1h-pirrolo[2,3-b]piridina y 7h-pirrolo[2,3-b]pirimidina sustituidos; procedimiento de preparación de los compuestos; composición farmacéutica; su uso en el tratamiento de condiciones óseas asociadas con la resorción de calcio, útiles en el tratamiento de la hipertensión pulmonar, artritis, entre otras. |
Country Status (22)
Country | Link |
---|---|
US (1) | US8314112B2 (es) |
EP (1) | EP2242756A2 (es) |
JP (1) | JP5643110B2 (es) |
KR (1) | KR20100116606A (es) |
CN (1) | CN101970435B (es) |
AR (1) | AR070127A1 (es) |
AU (1) | AU2009203694B2 (es) |
BR (1) | BRPI0907231A2 (es) |
CA (1) | CA2711845A1 (es) |
CL (1) | CL2009000028A1 (es) |
CO (1) | CO6331340A2 (es) |
CR (1) | CR11554A (es) |
EA (1) | EA201001126A1 (es) |
EC (1) | ECSP10010335A (es) |
IL (1) | IL206819A0 (es) |
MA (1) | MA31952B1 (es) |
MX (1) | MX2010007605A (es) |
PE (1) | PE20091306A1 (es) |
TN (1) | TN2010000305A1 (es) |
TW (1) | TW200934781A (es) |
WO (1) | WO2009087225A2 (es) |
ZA (1) | ZA201004602B (es) |
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WO2004065392A1 (en) * | 2003-01-24 | 2004-08-05 | Smithkline Beecham Corporation | Condensed pyridines and pyrimidines and their use as alk-5 receptor ligands |
DE602004014347D1 (de) * | 2003-03-12 | 2008-07-24 | Millennium Pharm Inc | Chinazolin-derivate als tgf-beta-inhibitoren |
US20050205625A1 (en) * | 2004-03-16 | 2005-09-22 | House Arthur G | Container support device, system, and method |
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-
2009
- 2009-01-08 AR ARP090100050A patent/AR070127A1/es not_active Application Discontinuation
- 2009-01-09 US US12/351,438 patent/US8314112B2/en not_active Expired - Fee Related
- 2009-01-09 EP EP20090700871 patent/EP2242756A2/en not_active Withdrawn
- 2009-01-09 KR KR1020107017744A patent/KR20100116606A/ko not_active Application Discontinuation
- 2009-01-09 CA CA2711845A patent/CA2711845A1/en not_active Abandoned
- 2009-01-09 WO PCT/EP2009/050225 patent/WO2009087225A2/en active Application Filing
- 2009-01-09 JP JP2010541794A patent/JP5643110B2/ja not_active Expired - Fee Related
- 2009-01-09 EA EA201001126A patent/EA201001126A1/ru unknown
- 2009-01-09 BR BRPI0907231A patent/BRPI0907231A2/pt not_active IP Right Cessation
- 2009-01-09 TW TW098100815A patent/TW200934781A/zh unknown
- 2009-01-09 CN CN200980108446.3A patent/CN101970435B/zh not_active Expired - Fee Related
- 2009-01-09 PE PE2009000024A patent/PE20091306A1/es not_active Application Discontinuation
- 2009-01-09 AU AU2009203694A patent/AU2009203694B2/en not_active Ceased
- 2009-01-09 CL CL2009000028A patent/CL2009000028A1/es unknown
- 2009-01-09 MX MX2010007605A patent/MX2010007605A/es active IP Right Grant
-
2010
- 2010-06-30 TN TN2010000305A patent/TN2010000305A1/fr unknown
- 2010-06-30 ZA ZA2010/04602A patent/ZA201004602B/en unknown
- 2010-06-30 MA MA32971A patent/MA31952B1/fr unknown
- 2010-07-02 CR CR11554A patent/CR11554A/es not_active Application Discontinuation
- 2010-07-05 IL IL206819A patent/IL206819A0/en unknown
- 2010-07-09 EC EC2010010335A patent/ECSP10010335A/es unknown
- 2010-07-12 CO CO10084491A patent/CO6331340A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2711845A1 (en) | 2009-07-16 |
MA31952B1 (fr) | 2010-12-01 |
AU2009203694A1 (en) | 2009-07-16 |
US8314112B2 (en) | 2012-11-20 |
EA201001126A1 (ru) | 2011-02-28 |
KR20100116606A (ko) | 2010-11-01 |
US20090181941A1 (en) | 2009-07-16 |
AR070127A1 (es) | 2010-03-17 |
TN2010000305A1 (en) | 2011-11-11 |
EP2242756A2 (en) | 2010-10-27 |
CO6331340A2 (es) | 2011-10-20 |
CN101970435A (zh) | 2011-02-09 |
ZA201004602B (en) | 2011-03-30 |
WO2009087225A3 (en) | 2009-11-05 |
PE20091306A1 (es) | 2009-09-24 |
AU2009203694B2 (en) | 2012-04-26 |
MX2010007605A (es) | 2010-08-02 |
ECSP10010335A (es) | 2010-08-31 |
WO2009087225A2 (en) | 2009-07-16 |
CN101970435B (zh) | 2014-07-02 |
TW200934781A (en) | 2009-08-16 |
IL206819A0 (en) | 2010-12-30 |
JP5643110B2 (ja) | 2014-12-17 |
BRPI0907231A2 (pt) | 2019-09-24 |
JP2011509279A (ja) | 2011-03-24 |
CR11554A (es) | 2010-08-11 |
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