CN101849935B - 芝麻素/异芝麻素组合物 - Google Patents

芝麻素/异芝麻素组合物 Download PDF

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Publication number
CN101849935B
CN101849935B CN201010139607XA CN201010139607A CN101849935B CN 101849935 B CN101849935 B CN 101849935B CN 201010139607X A CN201010139607X A CN 201010139607XA CN 201010139607 A CN201010139607 A CN 201010139607A CN 101849935 B CN101849935 B CN 101849935B
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China
Prior art keywords
sesamin
episesamin
composition
patent document
effect
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Expired - Fee Related
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CN201010139607XA
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Chinese (zh)
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CN101849935A (zh
Inventor
小野佳子
富森菜美乃
德田佐纪
橹木智裕
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Suntory Holdings Ltd
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Suntory Holdings Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C15/00—Butter; Butter preparations; Making thereof
    • A23C15/12—Butter preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN201010139607XA 2004-12-28 2005-12-28 芝麻素/异芝麻素组合物 Expired - Fee Related CN101849935B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2004381726 2004-12-28
JP2004381806 2004-12-28
JP2004-381806 2004-12-28
JP2004-381726 2004-12-28

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2005101353196A Division CN1796388B (zh) 2004-12-28 2005-12-28 芝麻素/异芝麻素组合物

Publications (2)

Publication Number Publication Date
CN101849935A CN101849935A (zh) 2010-10-06
CN101849935B true CN101849935B (zh) 2011-09-28

Family

ID=36614967

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201010139607XA Expired - Fee Related CN101849935B (zh) 2004-12-28 2005-12-28 芝麻素/异芝麻素组合物
CN2005101353196A Expired - Fee Related CN1796388B (zh) 2004-12-28 2005-12-28 芝麻素/异芝麻素组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2005101353196A Expired - Fee Related CN1796388B (zh) 2004-12-28 2005-12-28 芝麻素/异芝麻素组合物

Country Status (11)

Country Link
US (1) US20080275110A1 (enExample)
EP (1) EP1842540A4 (enExample)
JP (1) JP4995567B2 (enExample)
KR (1) KR101244586B1 (enExample)
CN (2) CN101849935B (enExample)
AU (1) AU2005320579B2 (enExample)
CA (1) CA2592532C (enExample)
MY (1) MY148121A (enExample)
SG (1) SG158183A1 (enExample)
TW (1) TW200633696A (enExample)
WO (1) WO2006070856A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685455B2 (en) 2005-03-31 2014-04-01 Suntory Holdings Limited Oil-in-water emulsions containing lignan-class compounds and compositions containing the same
EP1930333B1 (en) * 2005-09-30 2014-11-05 Suntory Holdings Limited Method and apparatus for producing episesamin-rich composition
RU2408598C2 (ru) * 2005-09-30 2011-01-10 Сантори Холдингз Лимитед Способ и устройство для получения композиций, обогащенных эписезамином
CN101404996B (zh) 2006-03-31 2011-05-18 三得利控股株式会社 含有木脂素类化合物的组合物
JP5409989B2 (ja) * 2006-04-03 2014-02-05 サントリーホールディングス株式会社 セサミン類含有動物用飲食物
KR101425241B1 (ko) * 2006-10-04 2014-08-01 산토리 홀딩스 가부시키가이샤 리그난류 화합물 함유 ｏ/ｗ/ｏ형 에멀션 및 그것을 함유하는 조성물
JP5276316B2 (ja) * 2007-12-28 2013-08-28 サントリーホールディングス株式会社 セサミン類及びケルセチン配糖体を含有する組成物
CN101342148B (zh) * 2008-07-03 2012-09-05 姚英 一种速效抗菌消炎、抗病毒的超浓缩天然蒜素片及其制备方法
JP5547891B2 (ja) * 2008-12-26 2014-07-16 サントリーホールディングス株式会社 セサミン類とエピガロカテキンガレートとを含有する組成物
CN104394864B (zh) * 2012-06-14 2016-10-05 三得利控股株式会社 含有芝麻素类、γ-谷维素和米胚芽油的组合物
JP2015140315A (ja) * 2014-01-29 2015-08-03 中日本カプセル 株式会社 ソフトカプセル用の充填組成物
CN107405329B (zh) * 2015-03-23 2021-04-09 三得利控股株式会社 昼夜节律改善用组合物
WO2021065664A1 (ja) * 2019-10-04 2021-04-08 サントリーホールディングス株式会社 生活活動量の維持、低下予防、低下抑制又は改善用組成物
CN115867289B (zh) * 2020-05-11 2026-04-14 三得利控股株式会社 含有nr及/或nmn与芝麻素类的组合物
CN113812618A (zh) * 2020-06-18 2021-12-21 陈信行 腐植酸芝麻素复方及其制程

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3001589B2 (ja) * 1989-07-21 2000-01-24 サントリー株式会社 リグナン類含有飲食物
EP0818196B1 (en) * 1989-07-21 2004-12-29 Suntory Limited Capsule, containing dioxabicyclo(3.3.0)octane compounds
US5211953A (en) * 1989-07-21 1993-05-18 Suntory, Limited Liver function improver
JP3075358B2 (ja) * 1990-04-03 2000-08-14 サントリー株式会社 肝機能改善剤
JP3283274B2 (ja) * 1991-06-15 2002-05-20 サントリー株式会社 新規組成物
JPH08268887A (ja) * 1995-02-01 1996-10-15 Suntory Ltd 高血圧症又はそれに起因する医学的症状の予防又は改善剤
ES2202454T3 (es) * 1995-07-04 2004-04-01 Suntory Limited Uso de un agente equilibrante para acidos grasos insaturados omega-3 y omega-6.
JP3205315B2 (ja) * 1999-04-28 2001-09-04 リノール油脂株式会社 ジオキサビシクロ〔３．３．０〕オクタン誘導体を有効成分とする体脂肪低減剤
EP1250052A1 (en) * 2000-01-25 2002-10-23 Juvenon, Inc. Nutritional supplements for aged pets

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JP特開2000－309533A 2000.11.07
Kushiro M.et al.Comparative effect of sesamin and episesamin on the activity and gene expression of enzymes in fatty acid oxidation and synthesis in rat liver.《Journal of Nutritional Biochemistry》.2002,第13卷289-295. *
Sawada R et al.The Metabolism and Distribution of Sesame Lignans(sesamin and episesame) in Rats.《Lipids》.1999,第34卷633-637. *

Also Published As

Publication number Publication date
AU2005320579A1 (en) 2006-07-06
CA2592532A1 (en) 2006-07-06
AU2005320579B2 (en) 2011-09-22
TW200633696A (en) 2006-10-01
KR20070089752A (ko) 2007-08-31
CN1796388A (zh) 2006-07-05
EP1842540A1 (en) 2007-10-10
JPWO2006070856A1 (ja) 2008-06-12
WO2006070856A1 (ja) 2006-07-06
SG158183A1 (en) 2010-01-29
MY148121A (en) 2013-02-28
KR101244586B1 (ko) 2013-03-25
EP1842540A4 (en) 2011-12-28
HK1088333A1 (en) 2006-11-03
JP4995567B2 (ja) 2012-08-08
CN101849935A (zh) 2010-10-06
HK1148465A1 (en) 2011-09-09
CN1796388B (zh) 2011-01-26
US20080275110A1 (en) 2008-11-06
CA2592532C (en) 2015-02-17
TWI368506B (enExample) 2012-07-21

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