JP5409989B2 - セサミン類含有動物用飲食物 - Google Patents
セサミン類含有動物用飲食物 Download PDFInfo
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- JP5409989B2 JP5409989B2 JP2006102312A JP2006102312A JP5409989B2 JP 5409989 B2 JP5409989 B2 JP 5409989B2 JP 2006102312 A JP2006102312 A JP 2006102312A JP 2006102312 A JP2006102312 A JP 2006102312A JP 5409989 B2 JP5409989 B2 JP 5409989B2
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Birds (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
参考例1 セサミン類の、油脂への溶解試験
セサミン類の、各種油脂への溶解度を調べた。セサミン類として、セサミン、エピセサミン及びセサミン:エピセサミン=51.1:48.2の混合物(竹本油脂株式会社)を用いた。セサミン、エピセサミンは、前記混合物より単離精製して調製したものである。これらのセサミン類を表1に示す5種の油脂各100gに溶解し、溶けきれなくなる限界量(溶解度)を調べた。結果を表1に示す。表1より、セサミン、エピセサミン及びその混合物は、溶解度が異なり、また、油脂の種類によっても溶解度が異なることがわかった。
セサミン類として、ゴマ油より単離精製された粉末状のセサミン及びエピセサミン混合物(セサミン:エピセサミン=51.1:48.2(重量比)、竹本油脂株式会社) (以下、「セサミン類混合物」ともいう。)を用い、表2に示す配合の錠剤並びにソフトカプセル剤A及びBを調製した。具体的には、錠剤は、所定量の割合で原料を混合した後、単発式打錠機にて打錠して直径11mm、重量330mgの錠剤を製造した。また、カプセル剤は、所定量の割合で原料を混合した後、カプセル皮膜(ゼラチン:74.0%、グリセリン:26.0%、水:適量)の中に常法(ロータリー法)により充填し、長径14.2mm、短径6.6mm、重量360mgのソフトカプセル剤A、及び長径9.5mm、短径6.7mm、重量250mgのソフトカプセル剤Bを製造した。
10匹のイヌを5匹ずつ、2群に分け、それぞれの群について、実施例1で調製した錠剤又はソフトカプセル剤Aを、表3に記載の量、4週間摂取させ(錠剤を摂取させた群を「錠剤群」、ソフトカプセル剤を摂取させた群を「カプセル剤群」とする)、通常食で得られなかった変化について評価した。表3に、各イヌの情報(犬種、年齢、体重)、錠剤又はカプセル剤の給与粒数、及び通常食を示す。
体臭 なし:+2、弱い:+1、 普通:0、やや強い:-1、 強い:-2
毛艶 ある:+2、ややある:+1、普通:0、あまりない:-1、 ない:-2
毛並み 良い:+2、やや良い:+1、普通:0、あまり良くない:-1、悪い:-2
それぞれのイヌについて、体臭、毛艶及び毛並みの変化量(=4週間摂取後の評価点 − 摂取前の評価点)を求め、各群のイヌの合計点を算出し、変化量の合計を各群のポイントとした。図1〜3に、体臭、毛艶及び毛並みのポイントをそれぞれ示す。体臭、毛艶、毛並みの項目全てにおいて、ポイントがプラスであることから、セサミン類含有非ヒト動物用飲食物の摂取により、体臭が軽減され、被毛状態が改善されることが示唆された。また、図1及び図2に示す体臭及び毛艶の結果から、錠剤群よりもカプセル群が良好な効果を得られることがわかった。これは、セサミン類を油脂に溶解させた状態で摂取させた方がその効果が高いことを示唆する。
表4に示す7匹のイヌについて、実施例1で調製したソフトカプセル剤Aを、表4中に記載のイヌの体重に応じた量で4週間摂取させ、通常食で得られなかった変化について評価した。摂取前、摂取2週間後、摂取4週間後における体臭、毛艶及び毛並みを、実施例2と同様に評価し、実施例2と同様の手法でポイントを求めた。
犬種:柴、年齢:3歳、体重:9kgのイヌに、実施例1で調製したソフトカプセル剤Bを1日1粒、4週間摂取させ、通常食で得られなかった変化について評価した。
Claims (9)
- セサミン類及び動物用飲食物として許容される添加剤を含有し、前記セサミン類が、非ヒト哺乳類に対して、1日当たり0.1〜10mg/kg体重の量で投与されることを特徴とする、非ヒト哺乳類の被毛処置及び/又は体臭処置のための非ヒト哺乳類用サプリメント。
- 前記セサミン類が、セサミン及び/又はエピセサミンである、請求項1に記載の非ヒト哺乳類用サプリメント。
- 更に油脂を含有する、請求項1又は2に記載の非ヒト哺乳類用サプリメント。
- 前記サプリメントが、カプセル剤または錠剤の形態である、請求項1〜3のいずれか1項に記載の非ヒト哺乳類用サプリメント。
- 前記サプリメントが、ソフトカプセルの形態である、請求項1〜3のいずれか1項に記載の非ヒト哺乳類用サプリメント。
- セサミン類を含むサプリメントを、セサミン類が非ヒト哺乳類に1日当たり0.1〜10mg/kg体重の量で摂取されるように非ヒト哺乳類に投与することを含む、非ヒト哺乳類の被毛処置方法及び/又は体臭処置方法。
- 前記サプリメントが、カプセル剤または錠剤の形態である、請求項6に記載の方法。
- 前記サプリメントが、ソフトカプセルの形態である、請求項6に記載の方法。
- 前記非ヒト哺乳類がペットである、請求項6〜8のいずれか1項に記載の方法。
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PCT/JP2007/057461 WO2007114437A1 (ja) | 2006-04-03 | 2007-04-03 | セサミン類含有動物用飲食物 |
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