CN1017626B - 生产新的细胞生长调节因子的方法 - Google Patents

生产新的细胞生长调节因子的方法

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Publication number
CN1017626B
CN1017626B CN86108955A CN86108955A CN1017626B CN 1017626 B CN1017626 B CN 1017626B CN 86108955 A CN86108955 A CN 86108955A CN 86108955 A CN86108955 A CN 86108955A CN 1017626 B CN1017626 B CN 1017626B
Authority
CN
China
Prior art keywords
cell
oncostatin
factor
suppress
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CN86108955A
Other languages
English (en)
Chinese (zh)
Other versions
CN86108955A (zh
Inventor
约斯·M·萨尔林格
莫哈麦德·舒亚布
翰斯·马奎特
马希亚·B·翰森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of CN86108955A publication Critical patent/CN86108955A/zh
Publication of CN1017626B publication Critical patent/CN1017626B/zh
Expired legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN86108955A 1985-12-20 1986-12-19 生产新的细胞生长调节因子的方法 Expired CN1017626B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81123585A 1985-12-20 1985-12-20
US811,235 1985-12-20
US93528386A 1986-11-26 1986-11-26
US935,283 1986-11-26

Publications (2)

Publication Number Publication Date
CN86108955A CN86108955A (zh) 1987-12-02
CN1017626B true CN1017626B (zh) 1992-07-29

Family

ID=27123452

Family Applications (1)

Application Number Title Priority Date Filing Date
CN86108955A Expired CN1017626B (zh) 1985-12-20 1986-12-19 生产新的细胞生长调节因子的方法

Country Status (29)

Country Link
JP (1) JP2559035B2 (no)
KR (1) KR920005920B1 (no)
CN (1) CN1017626B (no)
AT (1) AT400444B (no)
AU (2) AU601168B2 (no)
BE (1) BE905957A (no)
CA (1) CA1340296C (no)
CH (1) CH675727A5 (no)
CY (1) CY1608A (no)
DE (2) DE3643428A1 (no)
DK (1) DK174094B1 (no)
ES (1) ES2003180A6 (no)
FI (1) FI91484C (no)
FR (1) FR2597108B1 (no)
GB (1) GB2185485B (no)
GR (1) GR862936B (no)
HK (1) HK65691A (no)
HU (1) HU210694B (no)
IE (1) IE59415B1 (no)
IL (1) IL81017A (no)
IT (1) IT1213428B (no)
LU (1) LU86718A1 (no)
NL (1) NL8603209A (no)
NO (1) NO174556C (no)
NZ (1) NZ218634A (no)
OA (1) OA08494A (no)
PT (1) PT83986B (no)
SE (1) SE505059C2 (no)
SG (1) SG60891G (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645828A (en) * 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
US5681930A (en) * 1985-12-20 1997-10-28 Bristol-Myers Squibb Company Anti-oncostatin M monoclonal antibodies
NZ218634A (en) * 1985-12-20 1991-06-25 Oncogen Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits
NZ226799A (en) * 1987-11-06 1991-08-27 Oncogen Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor
NZ237533A (en) * 1990-03-29 1992-12-23 Bristol Myers Squibb Co Monoclonal antibodies which bind to oncostatin m, cell lines producing them
ZA912137B (en) * 1990-03-29 1992-11-25 Oncogen Monocional antibodies that inhibit growth of kaposi's sarcoma
WO1992002556A1 (en) * 1990-08-02 1992-02-20 Michael Valentine Agrez Human colon cancer cell-derived fibroblast elongation factor
ZA936925B (en) * 1992-09-25 1995-03-20 Lilly Co Eli Modified platelet factor-4.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132776A (en) * 1978-02-15 1979-01-02 University Patents, Inc. Delivery of immunologically active components of transfer factor
US4645828A (en) * 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
NZ218634A (en) * 1985-12-20 1991-06-25 Oncogen Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits

Also Published As

Publication number Publication date
GB2185485A (en) 1987-07-22
NL8603209A (nl) 1987-07-16
NO865178L (no) 1987-06-22
GB8629997D0 (en) 1987-01-28
FR2597108B1 (fr) 1991-02-15
IL81017A0 (en) 1987-03-31
FI91484C (fi) 1994-07-11
OA08494A (fr) 1988-07-29
AU639048B2 (en) 1993-07-15
AU601168B2 (en) 1990-09-06
AU6660886A (en) 1987-06-25
DK615386D0 (da) 1986-12-18
HUT43103A (en) 1987-09-28
SE8605459D0 (sv) 1986-12-18
KR870005645A (ko) 1987-07-06
LU86718A1 (fr) 1988-07-14
SE505059C2 (sv) 1997-06-16
CA1340296C (en) 1998-12-29
HU210694B (en) 1995-06-28
PT83986A (en) 1987-01-01
NO174556B (no) 1994-02-14
JPS62236498A (ja) 1987-10-16
DE3645095C2 (de) 1993-11-18
ATA340686A (de) 1995-05-15
IT1213428B (it) 1989-12-20
DE3643428C2 (no) 1990-08-23
KR920005920B1 (ko) 1992-07-24
DK615386A (da) 1987-06-21
GB2185485B (en) 1990-07-04
DE3643428A1 (de) 1987-09-24
FR2597108A1 (fr) 1987-10-16
IL81017A (en) 1993-01-14
AT400444B (de) 1995-12-27
IE863345L (en) 1987-06-20
AU6776590A (en) 1991-03-14
FI91484B (fi) 1994-03-31
HK65691A (en) 1991-08-23
IE59415B1 (en) 1994-02-23
NZ218634A (en) 1991-06-25
CH675727A5 (no) 1990-10-31
CY1608A (en) 1992-04-03
FI865156A (fi) 1987-06-21
FI865156A0 (fi) 1986-12-17
JP2559035B2 (ja) 1996-11-27
BE905957A (fr) 1987-06-17
SE8605459L (sv) 1987-06-21
IT8622787A0 (it) 1986-12-19
CN86108955A (zh) 1987-12-02
NO865178D0 (no) 1986-12-19
NO174556C (no) 1994-05-25
ES2003180A6 (es) 1988-10-16
SG60891G (en) 1991-08-23
PT83986B (pt) 1989-07-31
DK174094B1 (da) 2002-06-10
GR862936B (en) 1987-10-28

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C14 Grant of patent or utility model
GR01 Patent grant
C15 Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993)
OR01 Other related matters
C17 Cessation of patent right
CX01 Expiry of patent term