CN101678022A - 可用作蛋白激酶抑制剂的5-氰基-4-(吡咯并[2,3b]吡啶-3-基)嘧啶衍生物 - Google Patents

可用作蛋白激酶抑制剂的5-氰基-4-(吡咯并[2,3b]吡啶-3-基)嘧啶衍生物 Download PDF

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Publication number
CN101678022A
CN101678022A CN200780051641A CN200780051641A CN101678022A CN 101678022 A CN101678022 A CN 101678022A CN 200780051641 A CN200780051641 A CN 200780051641A CN 200780051641 A CN200780051641 A CN 200780051641A CN 101678022 A CN101678022 A CN 101678022A
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alkyl
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M·莫蒂摩尔
S·C·杨
S·R·L·埃弗里特
R·克内特尔
J·L·平德
A·P·鲁瑟福德
S·杜兰
G·布伦奇利
J·D·沙里耶
M·奥唐纳
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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CN200780051641A 2006-12-21 2007-12-21 可用作蛋白激酶抑制剂的5-氰基-4-(吡咯并[2,3b]吡啶-3-基)嘧啶衍生物 Pending CN101678022A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US87630706P 2006-12-21 2006-12-21
US60/876,307 2006-12-21
US92229107P 2007-04-06 2007-04-06
US60/922,291 2007-04-06
US94770707P 2007-07-03 2007-07-03
US60/947,707 2007-07-03
US98901407P 2007-11-19 2007-11-19
US60/989,014 2007-11-19
PCT/US2007/026190 WO2008079346A1 (en) 2006-12-21 2007-12-21 5-cyan0-4- (pyrrolo [2, 3b] pyridine-3-yl) -pyrimidine derivatives useful as protein kinase inhibitors

Publications (1)

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CN101678022A true CN101678022A (zh) 2010-03-24

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CN200780051641A Pending CN101678022A (zh) 2006-12-21 2007-12-21 可用作蛋白激酶抑制剂的5-氰基-4-(吡咯并[2,3b]吡啶-3-基)嘧啶衍生物

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US (3) US8247421B2 (https=)
EP (2) EP2124951B1 (https=)
JP (2) JP5406039B2 (https=)
KR (1) KR20090091350A (https=)
CN (1) CN101678022A (https=)
AR (1) AR064675A1 (https=)
AU (1) AU2007338754A1 (https=)
CA (1) CA2673472A1 (https=)
MX (1) MX2009006700A (https=)
NO (1) NO20092668L (https=)
NZ (1) NZ577798A (https=)
TW (1) TW200838517A (https=)
WO (1) WO2008079346A1 (https=)

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CN108276278A (zh) * 2013-11-13 2018-07-13 沃泰克斯药物股份有限公司 制备流感病毒复制抑制剂的方法
CN108473532A (zh) * 2015-11-02 2018-08-31 罗切斯特大学 硼替佐米缀合物和其使用方法
CN110372713A (zh) * 2019-08-15 2019-10-25 广州市汉普医药有限公司 一种普拉洛芬的精制纯化方法
WO2025228376A1 (zh) * 2024-04-30 2025-11-06 阿诺医药 (新加坡) 有限公司 Cyclin K降解剂药物及其抗体偶联物

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MX365640B (es) 2012-12-21 2019-06-10 Plexxikon Inc Compuestos y metodos para la modulacion de quinasas y sus indicaciones.
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LT3068776T (lt) 2013-11-13 2019-08-12 Vertex Pharmaceuticals Incorporated Gripo virusų replikacijos inhibitoriai
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WO2016210345A1 (en) * 2015-06-25 2016-12-29 The California Institute For Biomedical Research Composition and methods for inhibiting mammalian sterile 20-like kinase 1
EP3383875B1 (en) 2015-11-30 2022-02-09 Council Of Scientific & Industrial Research 3-pyrimidinyl pyrrolo [2,3-b] pyridine as anticancer agents and the process for the preparation thereof
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JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を治療するための方法
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