CN101668759A - [6,5]-双环gpr119g蛋白-偶合受体激动剂 - Google Patents
[6,5]-双环gpr119g蛋白-偶合受体激动剂 Download PDFInfo
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- CN101668759A CN101668759A CN200880013802A CN200880013802A CN101668759A CN 101668759 A CN101668759 A CN 101668759A CN 200880013802 A CN200880013802 A CN 200880013802A CN 200880013802 A CN200880013802 A CN 200880013802A CN 101668759 A CN101668759 A CN 101668759A
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- alkyl
- heteroaryl
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91595207P | 2007-05-04 | 2007-05-04 | |
| US60/915,952 | 2007-05-04 |
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|---|---|
| CN101668759A true CN101668759A (zh) | 2010-03-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200880013802A Pending CN101668759A (zh) | 2007-05-04 | 2008-04-30 | [6,5]-双环gpr119g蛋白-偶合受体激动剂 |
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| US (2) | US8093257B2 (enExample) |
| EP (1) | EP2152707B1 (enExample) |
| JP (1) | JP2010526146A (enExample) |
| CN (1) | CN101668759A (enExample) |
| AR (1) | AR066438A1 (enExample) |
| CL (1) | CL2008001270A1 (enExample) |
| ES (1) | ES2388315T3 (enExample) |
| PE (1) | PE20090213A1 (enExample) |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102036991A (zh) * | 2008-05-19 | 2011-04-27 | 霍夫曼-拉罗奇有限公司 | Gpr119受体激动剂 |
| CN102617548A (zh) * | 2011-01-31 | 2012-08-01 | 北京赛林泰医药技术有限公司 | 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用 |
| CN103328482A (zh) * | 2011-01-03 | 2013-09-25 | 韩美药品株式会社 | 用于调节g蛋白-偶联受体的新双环化合物 |
| CN103958495A (zh) * | 2011-06-09 | 2014-07-30 | 理森制药股份公司 | 作为gpr-119的调节剂的新型化合物 |
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| JP2010526145A (ja) | 2007-05-04 | 2010-07-29 | ブリストル−マイヤーズ スクイブ カンパニー | ［６，６］および［６，７］−二環式ｇｐｒ１１９ｇタンパク質結合受容体アゴニスト |
| JP5301539B2 (ja) * | 2007-07-17 | 2013-09-25 | ブリストル−マイヤーズ スクイブ カンパニー | Ｇｐｒ１１９ｇタンパク質共役受容体の調節方法および選択された化合物 |
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| BR112012025590A2 (pt) | 2010-04-08 | 2016-06-21 | Bristol Myers Squibb Co | análogos de pirimidinilpiperidiniloxipiridinona como moduladores de gpr119 |
| WO2011140161A1 (en) | 2010-05-06 | 2011-11-10 | Bristol-Myers Squibb Company | Benzofuranyl analogues as gpr119 modulators |
| CA2798610A1 (en) * | 2010-05-06 | 2011-11-10 | Bristol-Myers Squibb Company | Bicyclic heteroaryl compounds as gpr119 modulators |
| US20130096141A1 (en) * | 2010-06-18 | 2013-04-18 | Bernard R. Neustadt | Bicyclic heterocycle derivatives and methods of use thereof |
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| TW201204733A (en) | 2010-06-25 | 2012-02-01 | Kowa Co | Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| KR20120011357A (ko) * | 2010-07-23 | 2012-02-08 | 현대약품 주식회사 | 치환된 피리디논 유도체 및 이의 제조방법 |
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| WO2014011926A1 (en) | 2012-07-11 | 2014-01-16 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
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2008
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- 2008-04-30 JP JP2010507529A patent/JP2010526146A/ja not_active Withdrawn
- 2008-04-30 CN CN200880013802A patent/CN101668759A/zh active Pending
- 2008-04-30 US US12/112,053 patent/US8093257B2/en active Active
- 2008-04-30 ES ES08747131T patent/ES2388315T3/es active Active
- 2008-04-30 EP EP08747131A patent/EP2152707B1/en not_active Not-in-force
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- 2008-05-02 AR ARP080101888A patent/AR066438A1/es not_active Application Discontinuation
- 2008-05-02 CL CL200801270A patent/CL2008001270A1/es unknown
- 2008-05-02 TW TW097116366A patent/TW200848047A/zh unknown
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2011
- 2011-11-30 US US13/307,698 patent/US8476283B2/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102036991A (zh) * | 2008-05-19 | 2011-04-27 | 霍夫曼-拉罗奇有限公司 | Gpr119受体激动剂 |
| CN103328482A (zh) * | 2011-01-03 | 2013-09-25 | 韩美药品株式会社 | 用于调节g蛋白-偶联受体的新双环化合物 |
| CN102617548A (zh) * | 2011-01-31 | 2012-08-01 | 北京赛林泰医药技术有限公司 | 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用 |
| CN103958495A (zh) * | 2011-06-09 | 2014-07-30 | 理森制药股份公司 | 作为gpr-119的调节剂的新型化合物 |
| CN103958495B (zh) * | 2011-06-09 | 2018-06-22 | 理森制药股份公司 | 作为gpr-119的调节剂的化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120077826A1 (en) | 2012-03-29 |
| US8476283B2 (en) | 2013-07-02 |
| PE20090213A1 (es) | 2009-02-28 |
| AR066438A1 (es) | 2009-08-19 |
| WO2008137436A1 (en) | 2008-11-13 |
| ES2388315T3 (es) | 2012-10-11 |
| EP2152707B1 (en) | 2012-06-20 |
| EP2152707A1 (en) | 2010-02-17 |
| TW200848047A (en) | 2008-12-16 |
| JP2010526146A (ja) | 2010-07-29 |
| CL2008001270A1 (es) | 2008-09-12 |
| US8093257B2 (en) | 2012-01-10 |
| US20090018055A1 (en) | 2009-01-15 |
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