CN101668759A - [6,5]-双环gpr119g蛋白-偶合受体激动剂 - Google Patents
[6,5]-双环gpr119g蛋白-偶合受体激动剂 Download PDFInfo
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- CN101668759A CN101668759A CN200880013802A CN200880013802A CN101668759A CN 101668759 A CN101668759 A CN 101668759A CN 200880013802 A CN200880013802 A CN 200880013802A CN 200880013802 A CN200880013802 A CN 200880013802A CN 101668759 A CN101668759 A CN 101668759A
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- alkyl
- heteroaryl
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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| Application Number | Priority Date | Filing Date | Title |
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| US91595207P | 2007-05-04 | 2007-05-04 | |
| US60/915,952 | 2007-05-04 |
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| CN101668759A true CN101668759A (zh) | 2010-03-10 |
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| CN200880013802A Pending CN101668759A (zh) | 2007-05-04 | 2008-04-30 | [6,5]-双环gpr119g蛋白-偶合受体激动剂 |
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| US (2) | US8093257B2 (enExample) |
| EP (1) | EP2152707B1 (enExample) |
| JP (1) | JP2010526146A (enExample) |
| CN (1) | CN101668759A (enExample) |
| AR (1) | AR066438A1 (enExample) |
| CL (1) | CL2008001270A1 (enExample) |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102036991A (zh) * | 2008-05-19 | 2011-04-27 | 霍夫曼-拉罗奇有限公司 | Gpr119受体激动剂 |
| CN102617548A (zh) * | 2011-01-31 | 2012-08-01 | 北京赛林泰医药技术有限公司 | 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用 |
| CN103328482A (zh) * | 2011-01-03 | 2013-09-25 | 韩美药品株式会社 | 用于调节g蛋白-偶联受体的新双环化合物 |
| CN103958495A (zh) * | 2011-06-09 | 2014-07-30 | 理森制药股份公司 | 作为gpr-119的调节剂的新型化合物 |
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| WO2008137435A1 (en) | 2007-05-04 | 2008-11-13 | Bristol-Myers Squibb Company | [6,6] and [6,7]-bicyclic gpr119 g protein-coupled receptor agonists |
| EA018709B1 (ru) * | 2007-07-17 | 2013-10-30 | Бристол-Маерс Сквибб Компани | Пиридоновые агонисты сопряженного с g-белком рецептора gpr119 |
| CA2693169C (en) | 2007-07-19 | 2016-01-12 | Metabolex, Inc. | N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
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| MX2012011460A (es) | 2010-04-08 | 2012-11-23 | Squibb Bristol Myers Co | Analogos de pirimidinilpiperidiniloxipiridinona como moduladores de gpr119. |
| EA201270778A1 (ru) | 2010-05-06 | 2013-04-30 | Бристол-Майерс Сквибб Компани | Бициклические гетероарильные аналоги в качестве модуляторов рецептора gpr119 |
| WO2011140161A1 (en) | 2010-05-06 | 2011-11-10 | Bristol-Myers Squibb Company | Benzofuranyl analogues as gpr119 modulators |
| WO2011159657A1 (en) * | 2010-06-18 | 2011-12-22 | Merck Sharp & Dohme Corp. | Bicyclic heterocycle derivatives and methods of use thereof |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201204733A (en) | 2010-06-25 | 2012-02-01 | Kowa Co | Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
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| UY33805A (es) * | 2010-12-17 | 2012-07-31 | Boehringer Ingelheim Int | ?Derivados de dihidrobenzofuranil-piperidinilo, aza-dihidrobenzofuranilpiperidinilo y diaza-dihidrobenzofuranil-piperidinilo, composiciones farmacéuticas que los contienen y usos de los mismos?. |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
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2008
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- 2008-04-30 CN CN200880013802A patent/CN101668759A/zh active Pending
- 2008-04-30 WO PCT/US2008/061930 patent/WO2008137436A1/en not_active Ceased
- 2008-04-30 ES ES08747131T patent/ES2388315T3/es active Active
- 2008-04-30 JP JP2010507529A patent/JP2010526146A/ja not_active Withdrawn
- 2008-04-30 EP EP08747131A patent/EP2152707B1/en not_active Not-in-force
- 2008-04-30 US US12/112,053 patent/US8093257B2/en active Active
- 2008-05-02 CL CL200801270A patent/CL2008001270A1/es unknown
- 2008-05-02 TW TW097116366A patent/TW200848047A/zh unknown
- 2008-05-02 AR ARP080101888A patent/AR066438A1/es not_active Application Discontinuation
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2011
- 2011-11-30 US US13/307,698 patent/US8476283B2/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102036991A (zh) * | 2008-05-19 | 2011-04-27 | 霍夫曼-拉罗奇有限公司 | Gpr119受体激动剂 |
| CN103328482A (zh) * | 2011-01-03 | 2013-09-25 | 韩美药品株式会社 | 用于调节g蛋白-偶联受体的新双环化合物 |
| CN102617548A (zh) * | 2011-01-31 | 2012-08-01 | 北京赛林泰医药技术有限公司 | 作为gpr受体激动剂的双环杂芳基化合物及其组合物和应用 |
| CN103958495A (zh) * | 2011-06-09 | 2014-07-30 | 理森制药股份公司 | 作为gpr-119的调节剂的新型化合物 |
| CN103958495B (zh) * | 2011-06-09 | 2018-06-22 | 理森制药股份公司 | 作为gpr-119的调节剂的化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| PE20090213A1 (es) | 2009-02-28 |
| TW200848047A (en) | 2008-12-16 |
| JP2010526146A (ja) | 2010-07-29 |
| US8093257B2 (en) | 2012-01-10 |
| US8476283B2 (en) | 2013-07-02 |
| EP2152707A1 (en) | 2010-02-17 |
| EP2152707B1 (en) | 2012-06-20 |
| AR066438A1 (es) | 2009-08-19 |
| CL2008001270A1 (es) | 2008-09-12 |
| US20120077826A1 (en) | 2012-03-29 |
| ES2388315T3 (es) | 2012-10-11 |
| WO2008137436A1 (en) | 2008-11-13 |
| US20090018055A1 (en) | 2009-01-15 |
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