CN101502480A - Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies - Google Patents
Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies Download PDFInfo
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- CN101502480A CN101502480A CNA2009100372569A CN200910037256A CN101502480A CN 101502480 A CN101502480 A CN 101502480A CN A2009100372569 A CNA2009100372569 A CN A2009100372569A CN 200910037256 A CN200910037256 A CN 200910037256A CN 101502480 A CN101502480 A CN 101502480A
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Abstract
The invention discloses a Chinese traditional medicine composition having bacteriostatic, anti-dandruff and anti-itch functions. The active ingredients and weight percents of the composition are as follows: 1-50% of fructus cnidii, 1-60% of lightyellow sophora root, 0.5-40% of radix stemonae and 0.5-40% of densefruit pittany root-bark. Through conventional processes, the composition of the invention can be prepared into several kinds of hair cleanness and care products, such as liquid shampoos, cream shampoos or hair conditioners, etc. The composition of the invention is characterized in that natural and safe Chinese traditional medicines are used as main raw materials; reasonable processing technic is adopted; various ingredients are reasonably combined to reach the synergetic effect and are blended internally and externally via various ways to achieve the bacteriostatic, anti-dandruff and anti-itch effects.
Description
Technical field
The present invention relates to a kind of is the herbal composite antibacterial, anti-dandruff and itching-relieving efficacies that has of primary raw material preparation with the natural Chinese medicinal herb, being particularly related to a kind of is that having of primary raw material preparation is antibacterial, the hair of anti-dandruff and itching-relieving efficacies cleans, care product with the natural Chinese medicinal herb, as shampoo, hair cream or hair conditioner etc.
Background technology
Along with growth in the living standard, the popularizing of health perception, Chinese city resident's hair washing frequency also begins more and more to reach 3～3.5 times/week near developed country's level now.But want real and correct healthy philosophy of life to integrate with, it is far from being enough increasing the hair washing number of times simply, and we need be appreciated that and how scientifically remove hair washing, hair care.In the environment that we depend on for existence at present, pollution follows industrialization development to reach unprecedented serious, dust, ultraviolet, chemicals and various microorganism (antibacterial, mycete/yeast) are not being attacked our hair all the time, bring out multiple class problem, as the dandruff, scalp itch, hair bifurcated, hair are withered etc.
Dandruff is one of subject matter of puzzlement modern hair, the principal element that dandruff produces for the head metabolism occur unusual and pityrosporum furfur (chlosma) breeding, grow.Discover according to China's Healthy Education Associations scalp health research center, owing to do not note skin of head health care, bad hygienic habit and lack necessary anti-dandruff hair care knowledge, in the middle of Chinese adult, there is the male consumer of 59% female consumer and 63% all to be subjected to the puzzlement of dandruff always.The common shampoo of only simple usefulness is had one's hair wash, and can clean dirt at most and temporarily take away the dandruff on hair top layer, but can not be really from basic solution dandruff problem and the nutrition maintenance demand that satisfies hair itself.
Summary of the invention
The object of the present invention is to provide a kind of with the natural Chinese medicinal herb be primary raw material be prepared from have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, the various composition reasonable combination of said composition, Synergistic reach effect antibacterial, removing scurf and relieving itching by number of ways.
Provided by the invention have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and its active component and weight portion proportioning thereof are:
Fructus Cnidii 1～50, Radix Sophorae Flavescentis 1～60, the Radix Stemonae 0.5～40, Cortex Dictamni 0.5～40.
Preferred weight part proportioning of the active component of herbal composite of the present invention is:
Fructus Cnidii 10～30, Radix Sophorae Flavescentis 20～50, the Radix Stemonae 5～25, Cortex Dictamni 5～25.
Optimum weight part proportioning of the active component of herbal composite of the present invention is:
Fructus Cnidii 25, Radix Sophorae Flavescentis 35, the Radix Stemonae 20, Cortex Dictamni 20.
Above-mentioned have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, by common process, can make polytype hair cleaning, care product, as shampoo, hair cream or hair conditioner etc.
The main functional component of Fructus Cnidii is an osthole, and property is arduous, temperature; Have dispelling wind for relieving itching, dampness, parasiticidal effect (" the SHENGCAO property of medicine is wanted fully "), it is antipruritic to can be used for deposited skin ulcer, washes Ci leprosy (treatment eczema capitis), and anti-inflammation is regulated the metabolism of scalp keratinocyte.Through the extracorporeal bacteria inhibitor test evaluation, the osthole extract has very strong inhibitory action to the chlosma (M.furfur) that brings out the dandruff generation.
The main functional component of Radix Sophorae Flavescentis is matrine, oxymatrine, property hardship, cold; Have the effect of heat clearing and damp drying, parasite killing, be applicable to the dandruff, the scalp Pruritus, eczema, eczema, symptoms such as scabies leprosy are mainly followed the effect that " exopathogenic factor " approach reaches sterilizing and itch-relieving, anti-dandruff.
The Radix Stemonae contains various active compositions such as multiple alkaloid, polysaccharide, protein, malic acid such as (-)-Stemoninine, has effects such as gentle lung qi, cough-relieving, parasite killing, mainly follows the effect that " endogenous cause of ill " approach reaches expelling wind and removing dampness, cooling blood and removing stasis.
Cortex Dictamni contains dictamine, dictamnolactone, sitosterol, choline isoreactivity composition, has heat clearing and damp drying, dispels the wind, effect such as detoxifcation, is applicable to symptoms such as damp and hot sore, skin pruritus, mainly follows the effect that " endogenous cause of ill " reaches expelling wind and removing dampness, heat-clearing and toxic substances removing.
The characteristics of herbal composite of the present invention are to be primary raw material with the natural Chinese medicinal herb, utilize various composition reasonable combination, Synergistic, reach effect antibacterial, removing scurf and relieving itching by number of ways.Said composition can be widely used in the products such as shampoo, hair cream, hair conditioner by conventional processing technique, can effectively suppress dandruff and produce, alleviates symptoms such as scalp is itched, hair is withered.Said composition combines Traditional Chinese medical theory with the modern medicine study achievement is effective, follow " endogenous cause of ill ", " exopathogenic factor " principle simultaneously, reaches inside and outside effect of minoring, for comprehensively, thoroughly solve dandruff, the head pruritus problem provides a referential approach.
Description of drawings
Fig. 1 is the objective image analysis chart of product effect experiment of the present invention;
Fig. 2 is the subjective assessment datagram of product effect experiment of the present invention.
The invention will be further described below by the specific embodiment and product effect result of study.
The specific embodiment
The present invention will be described to enumerate a part of specific embodiment below, is necessary to be pointed out that at this following specific embodiment only is used for that the invention will be further described, does not represent limiting the scope of the invention.Some nonessential modifications that other people make according to the present invention and adjustment still belong to protection scope of the present invention.
Embodiment 1
A kind of have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and its active component and weight portion proportioning thereof are: Fructus Cnidii 25, Radix Sophorae Flavescentis 35, the Radix Stemonae 20, Cortex Dictamni 20.
A kind of have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and its active component and weight portion proportioning thereof are: Fructus Cnidii 15, Radix Sophorae Flavescentis 40, the Radix Stemonae 25, Cortex Dictamni 20.
A kind of have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and its active component and weight portion proportioning thereof are: Fructus Cnidii 10, Radix Sophorae Flavescentis 50, the Radix Stemonae 30, Cortex Dictamni 10.
Embodiment 4
A kind of have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and its active component and weight portion proportioning thereof are: Fructus Cnidii 20, Radix Sophorae Flavescentis 30, the Radix Stemonae 15, Cortex Dictamni 35.
Embodiment 5
A kind of have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and its active component and weight portion proportioning thereof are: Fructus Cnidii 30, Radix Sophorae Flavescentis 35, the Radix Stemonae 20, Cortex Dictamni 15.
The herbal composite that above embodiment describes can be mixed with multiple hair cleaning, care product, as shampoo, hair cream or hair conditioner etc. by common process.
Fungistatic effect research
By the shampoo product that the foregoing description 1 makes, the compositions addition is 0.20% (w/w), is numbered NF, the applicant carried out to hair (skin) easily grow, the bacteriostatic test of bacterial infection and fungus, result of the test is as follows:
1. test specimen
Totally 4 sections of shampoos, number as follows:
NF, KB, ZY (ZHIYA): Southern Co. LiJinJi Co., Ltd provides; BW: the well-known Chinese herbal medicine notion anti-dandruff shampoo water of selling on the market, (KB is not for adding herbal composite, the identical blank shampoo of all the other compositions and NF).
2. test index
Inhibition zone diameter (mm); Minimum inhibitory concentration (MIC, %)
3. result of the test
3.1 broad spectrum activity bacteriostatic test result
Annotate:
*The D value is the inhibition zone diameter sum to three kinds of strain subjects, and the antibacterial bacterial concentration is about 5.0 * 10
7Cfu/ml, mycete and yeast liquid concentration are about 3.5 * 10
6Cfu/ml.
According to test data as can be known, except that KB, other 3 kinds of shampoos are to strain subject comparatively responsive (D〉27.0), and wherein the fungistatic effect of NF is best.
3.2 feature bacterium bacteriostatic test result
| The sample title | Strain subject | Minimum inhibitory concentration (MIC) |
| NF | Chlosma (ATCC 14521) | 0.10％ |
| KB | Chlosma (ATCC 14521) | >0.50％ |
| ZY | Chlosma (ATCC 14521) | 0.30％ |
| BW | Chlosma (ATCC 14521) | 0.15％ |
Annotate: the activity of chlosma bacterium liquid is about 4.0 * 10
5Cfu/ml.
According to test data as can be known, 4 kinds of shampoos all have certain inhibitory action to strain subject, and wherein the fungistatic effect of NF is better than ZY and BW.
Human efficiency's research
By the shampoo sample NF that the foregoing description 1 makes, the applicant has carried out human body antidandruff effect demonstration test, and result of the test is as follows:
1. experiment material
1.1 test specimen
Totally 2 kinds of shampoos are numbered NF and BW (the same).
1.2 subjects
The standard of including in is: the non-pathologic dandruff phenomenon of medium or medium above degree, left and right sides dandruff gradient of infection is roughly the same.
1.3 test number
Choose 26 volunteers altogether and test, be divided into 2 groups, actual finishing number 20 people, wherein male 10 people, women 10 people, 20～50 years old age.
2. experimental design and method
2.1 objective image analysis
Operation sequence according to standard is combed the right and left dandruff to glass plate respectively, covers with the onesize glass plate of another piece then, seals and preserves.In 14 days, glass plate is carried out graphical analysis.
Under the cold light source lighting condition, under black background, gather glass plate image and preservation with monochromatic CCD camera.By analysis software picture is analyzed, calculated the area percentage (%) of dandruff.
2.2 subjective assessment dandruff amount
The technical staff marks to the dandruff amount of the right and left respectively according to standards of grading:
0 ... no dandruff; 1 ... fragmentary dandruff; 2 ... a small amount of dandruff; 3 ... the moderate dandruff; 4 ... a large amount of dandruffs.
2.3 adaptation of product evaluation
Technical staff and volunteer carry out the Adaptability Evaluation of product respectively to the right and left, the Adaptability Evaluation parameter comprises the rubescent situation of scalp, scalp itch and burn feeling, and wherein the rubescent situation of scalp is estimated by the technical staff; Scalp itch, burn feeling are estimated by the volunteer.
Scalp is rubescent, scalp itch, burn feeling situation grading standard:
0 ... do not have; 1 ... slightly; 2 ... medium; 3 ... seriously; 4 ... very serious.
3. experimental result
3.1 objective image analysis
As shown in Figure 1, from image analysis data on the whole, the BW group reduces with the increase of service time substantially with NF group dandruff amount.Product uses the later stage (t5) to compare with using early stage (t0), and the dandruff amount of NF group shows as significance and reduces; The dandruff amount of BW group is on a declining curve, but there was no significant difference.
3.2 subjective assessment
As shown in Figure 2, from subjective data integral body, the BW group reduces with the increase of service time substantially with NF group dandruff amount.Product uses the later stage (t5) to compare with using early stage (t0), and two test group dandruff amounts all show as significance and reduce.
3.3 adaptation of product evaluation
Table 1.Result of the feeling itching of scalp
For scalp itch, scalp is rubescent and situation such as burn feeling, uses the mitigation (t4 compares with t0) that all shows behind NF and the BW to a certain degree.
4. brief summary
Use shampoo NF after one month, by objective analysis and subjective assessment, the dandruff amount all is minimizing trend, to scalp itch, scalp is rubescent and situation such as burn feeling also has to a certain degree mitigation.
Claims (4)
1. one kind has herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, it is characterized in that the active component of said composition and weight portion proportioning thereof are: Fructus Cnidii 1～50, Radix Sophorae Flavescentis 1～60, the Radix Stemonae 0.5～40, Cortex Dictamni 0.5～40.
2. according to claim 1 have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and wherein the weight portion proportioning of each active component is: Fructus Cnidii 10～30, Radix Sophorae Flavescentis 20～50, the Radix Stemonae 5～25, Cortex Dictamni 5～25.
3. according to claim 1 have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies, and wherein the weight portion proportioning of each active component is: Fructus Cnidii 25, Radix Sophorae Flavescentis 35, the Radix Stemonae 20, Cortex Dictamni 20.
4. describedly have a herbal composite antibacterial, anti-dandruff and itching-relieving efficacies according to claim 1,2 or 3, it is characterized in that described herbal composite is shampoo, hair cream or hair conditioner.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100372569A CN101502480A (en) | 2009-02-19 | 2009-02-19 | Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100372569A CN101502480A (en) | 2009-02-19 | 2009-02-19 | Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies |
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| CN101502480A true CN101502480A (en) | 2009-08-12 |
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|---|---|---|---|
| CNA2009100372569A Pending CN101502480A (en) | 2009-02-19 | 2009-02-19 | Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies |
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| CN102138994A (en) * | 2010-10-31 | 2011-08-03 | 仙桃市魏氏生物工程有限责任公司 | Pharmaceutical composition for preventing and treating black gill disease of aquatic animals |
| CN102258727A (en) * | 2011-07-07 | 2011-11-30 | 吉林农业大学 | External medicament for treating equine seborrheic dermatitis and preparation method thereof |
| CN102335376A (en) * | 2011-08-28 | 2012-02-01 | 张绍金 | Compound preparation with stronger antibacterial and itch relieving functions of plant extract |
| CN102614102A (en) * | 2012-04-27 | 2012-08-01 | 昆明远方生物制品有限公司 | Dandruff-removing medicinal composition and preparation method thereof |
| CN103285122A (en) * | 2013-06-13 | 2013-09-11 | 金品红 | Traditional Chinese medicine composition for treating swine mange and scab and preparation method thereof |
| CN103721137A (en) * | 2013-12-11 | 2014-04-16 | 郑州市康健电子产品研究所 | Externally-used traditional Chinese medicine lotion for removing dandruff and hair oil |
| CN103816092A (en) * | 2014-03-18 | 2014-05-28 | 无限极（中国）有限公司 | Traditional Chinese medicine extractive for washing hair as well as preparation method and raw material composition thereof |
| CN104740456A (en) * | 2013-12-25 | 2015-07-01 | 罗兴富 | Paste shampoo with sterilization, itch relieving and dandruff removing functions, and preparing method of same |
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| CN105534820A (en) * | 2016-01-25 | 2016-05-04 | 柳州三农科技有限公司 | Pure natural anti-dandruff hair-moisturizing shampoo and preparation method thereof |
| CN105963427A (en) * | 2016-06-21 | 2016-09-28 | 安徽诚亚生物科技有限公司 | Scurf removal traditional Chinese medicine formula |
| CN107095824A (en) * | 2017-06-21 | 2017-08-29 | 汕头市深特宝洁实业有限公司 | A kind of plant anti-dandruff shampoo and its preparation |
| CN107184491A (en) * | 2017-07-20 | 2017-09-22 | 唐少钦 | A kind of Chinese herbal medicine anti-dandruff and itching-relieving shampoo and preparation method thereof |
| CN107349369A (en) * | 2017-07-27 | 2017-11-17 | 浙江章光101有限公司 | One kind is deoiled antipruritic aromatising essence liquid Chinese medicine preparation |
| CN108653637A (en) * | 2018-08-31 | 2018-10-16 | 冯立光 | It is a kind of to treat dermopathic externally applied drug and preparation method thereof |
| CN112656732A (en) * | 2021-01-12 | 2021-04-16 | 广州市雅蔻化妆品有限公司 | Dandruff-removing and itching-relieving shampoo and preparation method thereof |
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| CN114681365A (en) * | 2022-04-29 | 2022-07-01 | 福建片仔癀化妆品有限公司 | Shampoo with oil control and mite removal effects and preparation method thereof |
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2009
- 2009-02-19 CN CNA2009100372569A patent/CN101502480A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138994A (en) * | 2010-10-31 | 2011-08-03 | 仙桃市魏氏生物工程有限责任公司 | Pharmaceutical composition for preventing and treating black gill disease of aquatic animals |
| CN102138994B (en) * | 2010-10-31 | 2014-12-10 | 仙桃市魏氏生物工程有限责任公司 | Pharmaceutical composition for preventing and treating black gill disease of aquatic animals |
| CN102258727A (en) * | 2011-07-07 | 2011-11-30 | 吉林农业大学 | External medicament for treating equine seborrheic dermatitis and preparation method thereof |
| CN102258727B (en) * | 2011-07-07 | 2013-01-30 | 吉林农业大学 | External medicament for treating equine seborrheic dermatitis and preparation method thereof |
| CN102335376A (en) * | 2011-08-28 | 2012-02-01 | 张绍金 | Compound preparation with stronger antibacterial and itch relieving functions of plant extract |
| CN102335376B (en) * | 2011-08-28 | 2013-04-03 | 张绍金 | Compound preparation with stronger antibacterial and itch relieving functions of plant extract |
| CN102614102A (en) * | 2012-04-27 | 2012-08-01 | 昆明远方生物制品有限公司 | Dandruff-removing medicinal composition and preparation method thereof |
| CN103285122A (en) * | 2013-06-13 | 2013-09-11 | 金品红 | Traditional Chinese medicine composition for treating swine mange and scab and preparation method thereof |
| CN103285122B (en) * | 2013-06-13 | 2015-03-04 | 金品红 | Traditional Chinese medicine composition for treating swine mange and scab and preparation method thereof |
| CN103721137A (en) * | 2013-12-11 | 2014-04-16 | 郑州市康健电子产品研究所 | Externally-used traditional Chinese medicine lotion for removing dandruff and hair oil |
| CN104740456A (en) * | 2013-12-25 | 2015-07-01 | 罗兴富 | Paste shampoo with sterilization, itch relieving and dandruff removing functions, and preparing method of same |
| CN104771335A (en) * | 2014-01-14 | 2015-07-15 | 北京章光101科技股份有限公司 | Plant anti-dandruff nourishing essence lotion and preparation method thereof |
| CN104771335B (en) * | 2014-01-14 | 2018-01-19 | 北京章光101科技股份有限公司 | Anti-dandruff nourishing essence dew of plant and preparation method thereof |
| CN103816092B (en) * | 2014-03-18 | 2015-11-18 | 无限极（中国）有限公司 | A kind of Chinese medicine extract, its preparation method and feedstock composition thereof for having one's hair wash |
| CN103816092A (en) * | 2014-03-18 | 2014-05-28 | 无限极（中国）有限公司 | Traditional Chinese medicine extractive for washing hair as well as preparation method and raw material composition thereof |
| CN105534820A (en) * | 2016-01-25 | 2016-05-04 | 柳州三农科技有限公司 | Pure natural anti-dandruff hair-moisturizing shampoo and preparation method thereof |
| CN105963427A (en) * | 2016-06-21 | 2016-09-28 | 安徽诚亚生物科技有限公司 | Scurf removal traditional Chinese medicine formula |
| CN107095824A (en) * | 2017-06-21 | 2017-08-29 | 汕头市深特宝洁实业有限公司 | A kind of plant anti-dandruff shampoo and its preparation |
| CN107184491A (en) * | 2017-07-20 | 2017-09-22 | 唐少钦 | A kind of Chinese herbal medicine anti-dandruff and itching-relieving shampoo and preparation method thereof |
| CN107349369A (en) * | 2017-07-27 | 2017-11-17 | 浙江章光101有限公司 | One kind is deoiled antipruritic aromatising essence liquid Chinese medicine preparation |
| CN107349369B (en) * | 2017-07-27 | 2018-07-10 | 浙江章光101有限公司 | One kind is deoiled antipruritic aromatising essence liquid Chinese medicine composition |
| CN108653637A (en) * | 2018-08-31 | 2018-10-16 | 冯立光 | It is a kind of to treat dermopathic externally applied drug and preparation method thereof |
| CN112656732A (en) * | 2021-01-12 | 2021-04-16 | 广州市雅蔻化妆品有限公司 | Dandruff-removing and itching-relieving shampoo and preparation method thereof |
| CN114558068A (en) * | 2022-03-16 | 2022-05-31 | 薛辉 | Preparation technology of ointment for removing dandruff and treating stubborn tinea and pruritus |
| CN114681365A (en) * | 2022-04-29 | 2022-07-01 | 福建片仔癀化妆品有限公司 | Shampoo with oil control and mite removal effects and preparation method thereof |
| CN114681365B (en) * | 2022-04-29 | 2023-10-27 | 福建片仔癀化妆品有限公司 | Shampoo with oil control and mite removal effects and preparation method thereof |
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