CN114010571B - Natural extract for soothing skin and improving skin quality and application thereof - Google Patents

Abstract

The invention belongs to the field of natural extracts, and discloses a natural extract for soothing and improving skin and application thereof. The active ingredients of the natural extract are flower extracts of safflower, albizia flower, paris polyphylla, lonicera confusa, tropaeolum majus, peony and polygala japonica. The invention selects various flowers as raw materials in a breakthrough way and extracts the essence in the flowers. In the prescription, safflower is used as a monarch drug to consolidate the constitution, activate blood, relieve depression and calm nerves; the albizia flower and the paris polyphylla are used as ministerial drugs and have the effects of diminishing inflammation, relieving pain, relieving and soothing the nerves; flos Lonicerae, flos Trollii, and flos moutan can be used as adjuvant for dispelling wind and heat, and soothing and relieving itching; baijin Hua is used as a guide to clear away heat and toxic material, remove red and relieve swelling. The extracts have synergistic effect, and have good antiinflammatory and antioxidant effects. Has good skin-care effect aiming at immediate symptom relief of sensitive skin and long-acting barrier consolidation. The product has natural flower fragrance, gives people natural joyful feeling when in use, relieves mental stress, and can better improve sensitive skin.

Description

Natural extract for soothing skin and improving skin quality and application thereof

Technical Field

The invention relates to a natural extract, in particular to a natural extract with the functions of soothing the skin and improving the skin quality and application thereof.

Background

The skin is the largest organ of the human body, is directly contacted with the external environment, and has the functions of protecting, excreting, regulating body temperature, sensing external stimulation and the like. The health of the skin has a very important impact on the health of a person. The health condition of the skin exposed to the outside, such as the face and hands, also directly shows the mental state and the look and feel of others. The maintenance of skin health, particularly facial skin, is of concern.

The skin is easily affected by the environment because of direct contact with the environment, especially the skin of the face. The allergy problem is caused by illumination, air, water, biology and daily living goods. Work, stress of life, age, sex, hormone levels, genetic factors, etc. also have an effect on the skin. The long-term use of cosmetics or skin care products can also affect the skin. These factors, alone or in combination, cause the skin to develop into a sensitive skin condition.

Sensitive Skin (SS) refers to a high-response state of skin under physiological or pathological conditions, mainly occurs on the face, and clinically shows subjective symptoms such as burning, stabbing pain, itching and tightness of skin when being stimulated by physical, chemical and mental factors, with or without objective signs such as erythema, scaling and telangiectasia.

The problem of skin sensitivity is a global problem all the time, along with the development of science and technology, people suffering from skin sensitivity are more and more, and people pay more and more attention to the problem of skin sensitivity. According to the report of Chinese consensus on sensitive skin diagnosis and treatment experts published in the journal of Chinese dermatosis (vol. 31, 1, 2017), the incidence rate of sensitive skin in all countries in the world is high, and the reported incidence rate difference among different parts is large due to different investigation methods, namely 25.4-89.9% in Europe and about 50% in Australia. The incidence rate of women is generally higher than that of men, the incidence rate of American women is 22.3-50.9%, the incidence rate of Asian women is 40-55.98%, and the incidence rate of Chinese women is 36.1%.

Natural extracts are used for general and less irritating properties and are an important source for developing and improving sensitive skin. The traditional theory of traditional Chinese medicine is that the skin is treated by skin, the skin medicine enters the skin and directly reaches a patient to play a role in beautifying, and for example, poplar bark, magnolia bark, pomegranate bark and the like are commonly used traditional Chinese medicines for skin conditioning. Zhao Lianhao, liu Xiaoxin and Liu Xiaolin anti-allergic decoction is used for treating cosmetic dermatitis in 50 cases (J) in Shanxi traditional Chinese medicine, 2004,25 (010): 894-895, and anti-allergic decoction (rhizoma atractylodis, mangnolia officinalis, dried tangerine peel, honeysuckle, cortex dictamni and the like) is used for treating cosmetic dermatitis, so that a good curative effect is achieved. Hou Huixian, zhou Li, liu Kun and the like, clinical research on treatment of facial allergic dermatitis by traditional Chinese medicine desensitization clear water pills [ J ] in Chinese medicine and pharmacology, 2011 (03): 140-141. The medicine composition comprises 20g of tree peony bark, 20g of oriental wormwood, 25g of divaricate saposhnikovia root, 15g of incised notopterygium rhizome, 15g of dahurian angelica root, 20g of broom cypress fruit, 25g of baical skullcap root, 20g of cicada slough, 15g of lightyellow sophora root, 25g of indigowoad leaf and 30g of astragalus root. Also obtains better curative effect. However, all the compositions need to be prepared into oral preparations, so the use is inconvenient, and the efficacy is relatively single.

The natural extract composition which is more convenient to use and has better skin improvement effect is developed, and has very practical significance.

Disclosure of Invention

The invention aims to overcome at least one defect of the prior art and provides a natural extract for relieving pressure and improving skin quality and application thereof.

The technical scheme adopted by the invention is as follows:

in a first aspect of the present invention, there is provided:

a natural extract comprises the following active ingredients: safflower, albizia flower, paris polyphylla, lonicera confusa, tropaeolum majus, peony and lily.

In some examples, the active ingredient is an aqueous extract of the starting material.

In some examples, the aqueous extract is extracted using microfluidization.

In some examples, the natural extract comprises the following components in percentage by mass: 3 to 8 percent of safflower (Carthamus TINCTORIUS) flower extract, 3 to 8 percent of ALBIZIA JULIBRISSIN (Albizia JULIBRISSIN) flower extract, 0.5 to 1.0 percent of PARIS POLYPHYLLA (Paris POLYPHYLLA CHINENSIS) flower extract, 3 to 8 percent of LONICERA CONFUSA (Lonicera CONFUSA) extract, 3 to 8 percent of Tropaeolum (Tropaeolum MAJUS) flower extract, 3 to 8 percent of peony (Paeonia SUFFRUTICOSA) flower extract and 3 to 8 percent of flos lonicerae (Centauritylaea).

In a second aspect of the present invention, there is provided:

a skin care product additive comprises an auxiliary material and an active ingredient, wherein the active ingredient is the natural extract of the first aspect of the invention, and the auxiliary material comprises water, alcohol and p-hydroxyacetophenone.

In some examples of skin care additives, the composition by mass is: 30 to 40 percent of active component, 20 to 30 percent of butanediol, 5 to 10 percent of glycerol, 5 to 10 percent of sorbitol, 0.2 to 1.0 percent of hydroxyacetophenone and a proper amount of water.

In a third aspect of the present invention, there is provided:

a composition for improving skin quality comprises auxiliary materials and functional components, wherein the functional components comprise the skin care product additive of the second aspect of the invention.

In some examples, the skin care product additive is added in an amount of 1.0 to 5.0% by mass.

In some examples, the composition is a skin care product.

In some examples, the composition is selected from the group consisting of a cream, a lotion, a serum, a gel, a mask.

In some examples, the composition is selected from the group consisting of a wash care, a cleansing skin care product.

The invention has the beneficial effects that:

in some embodiments of the invention, various flowers are selected as raw materials in a breakthrough manner, and essences in the flowers are extracted. In the formula, safflower is taken as a monarch drug, so that the effects of consolidating body resistance, promoting blood circulation, relieving depression and calming the nerves are achieved; the albizia flower and the paris polyphylla are used as ministerial drugs and have the effects of diminishing inflammation, relieving pain, relieving and soothing the nerves; flos Lonicerae, flos Trollii, and flos moutan can be used for dispelling wind and heat, and soothing and relieving itching; baijin Hua is used as a messenger to clear away heat and toxic material, remove red and relieve swelling. The extracts have synergistic effect, and have good antiinflammatory and antioxidant effects. Has good skin-care effect aiming at immediate symptom relief of sensitive skin and long-acting barrier consolidation.

According to some embodiments of the invention, the product has natural flower fragrance, gives people natural pleasure when in use, relieves mental stress, and can better improve sensitive skin.

Detailed Description

In the natural extract of the invention, the introduction of each raw material is as follows:

carthami flos, which is crocus sativus of IridaceaeCrocus sativus L.The dry column head of (2). Sweet and mild in nature and taste. Meridian tropism means heart and liver meridian tropism. Has the effects of promoting blood circulation, removing blood stasis, cooling blood, removing toxic substance, resolving stagnation and tranquilizing mind. The traditional Chinese medicine composition is mainly used for treating amenorrhea, abdominal mass, postpartum stasis, toxic-heat macula, melancholy, stuffiness, palpitation and mania.

Flos Albizziae, which is plant Albizziae of LeguminosaeAlbizia julibrissin DurazzThe dried inflorescence of (1). Collected in sunny days when flowers are open in summer and dried in the sun in time. Sweet and mild in nature and taste. Meridian tropism means heart and liver meridian tropism. Has the effects of resolving depression and soothing nerves. Mainly treats uneasiness, melancholy and insomnia.

Paris polyphylla (academic name:Paris polyphylla) Is a plant of Paris of Liliaceae. Bitter taste and cold nature. It enters heart, liver and lung meridians. Contains multiple saponin components, and has antiinflammatory and antipruritic effectsThe main effects of the solidago virgaurea, and simultaneously, the solidago virgaurea has the effects of clearing away heat and toxic materials, resisting inflammation and stopping bleeding, resisting bacteria, and calming and soothing the nerves.

Flos Lonicerae is Lonicera Macranthoides Miq of CaprifoliaceaeLonicera macranthoidesHand．-MazzLonicera hypoglauca MiqLonicera hypoglauca MiqOr Lonicera japonica Thunb Lonicera confusa DC.The dried flower buds or the flowers with initial blossoming. Sweet and cold in nature. Meridian tropism means that it enters lung, heart and stomach meridians. Has the effects of clearing away heat and toxic materials and cooling and dispersing wind-heat. The main indications are carbuncle, furuncle, throat impediment and erysipelas. Dysentery due to heat-toxicity and bloody stool, cold due to wind-heat, and warm-heat.

The herba Ecliptae is Tropaeolum maju L of Ecliptae genus of Ecliptae family. The herbs are generally used as herbs. Collected in autumn and winter, it is used in fresh. The main functional indications are as follows: clearing away heat and toxic material. Can be used for treating conjunctivitis, carbuncle, furuncle, and toxic swelling. The invention selects the flowers thereof for extracting active ingredients.

The peony is Paeonia suffruticosa Andr of RanunculaceaePaeonia suffruticosa AndrThe root bark is usually used as the medicine, and its nature and taste are bitter, pungent and slightly cold. Meridian tropism includes heart, liver and kidney meridians. Has the effects of clearing heat and cooling blood, and promoting blood circulation by removing blood stasis. The main treatment is used for treating warm-toxicity macula, hematemesis and epistaxis, night fever and early coolness, no sweating and bone steaming, amenorrhea and dysmenorrheal, carbuncle, swelling and sore, traumatic injury and pain. In the invention, flowers are selected for extracting active ingredients.

Baijin flower, also known as rodgersia podophylla (academic name:Centaurium erythraea) Red Baijin flower. Contains functional components such as chlorogenic acid and the like, has wide antibacterial effect, and can supplement pure moisture for skin, relieve easily-dried skin and associate healthy skin.

In the formula, safflower is taken as a monarch drug, so that the effects of consolidating body resistance, promoting blood circulation, relieving depression and calming the nerves are achieved; the albizia flower and the paris polyphylla are used as ministerial drugs and have the effects of diminishing inflammation, relieving pain, relieving and soothing the nerves; flos Lonicerae, flos Trollii, and flos moutan can be used for dispelling wind and heat, and soothing and relieving itching; the plumeria rubra and the honeysuckle flower are used as guiding drugs for clearing heat and removing toxicity, and dispelling redness and reducing swelling. The extracts have synergistic effect, and have good antiinflammatory and antioxidant effects. The skin care product can immediately relieve symptoms of sensitive skin and strengthen a barrier for a long time.

The technical scheme of the invention is further explained by combining the examples.

In the following examples, each of the raw materials was extracted by a microfluidization method, unless otherwise specified. Specifically, the raw material was extracted using a microfluidizer disclosed in CN107537180 a. According to the raw materials (dry weight): water =1:20, extracting at a temperature of not higher than 30 ℃, and concentrating to a specific gravity of about 1.1.

Example 1

The natural extract comprises the following components:

safflower extract	8	Portions are prepared
			Albizzia julibrissin flower extract	3	Portions are
Paris polyphylla (Hemsl.) Merr extract	0.6	Portions are prepared
			Flos Lonicerae extract	6	Portions are
Tropaeolum majus extract	4	Portions are
			Peony extract	5	Portions are
Flos Lonicerae extract	5	Portions are prepared

The skin care product additive comprises the following components:

components	Content/%)
		Natural extract	31.6
Butanediol	25
		Glycerol	7
Sorbitol	8
		Hydroxyacetophenones	0.5
Water (I)	Balance of

Example 2

The natural extract comprises the following components:

safflower extract	5	Portions are prepared
			Albizzia julibrissin extract	5	Portions are
Paris polyphylla Smith extract	0.5	Portions are
			Flos Lonicerae extract	5	Portions are
Tropaeolum majus extract	8	Portions are prepared
			Peony extract	6	Portions are
Baijin flower extract	6	Portions are

The skin care product additive comprises the following components:

components	Content/%
		Natural extract	35.5
Butanediol	30
		Glycerol	6
Sorbitol	10
		Hydroxyacetophenones	0.2
Water (W)	Allowance of

Example 3

The natural extract comprises the following components:

safflower extract	6	Portions are prepared
			Albizzia julibrissin extract	4	Portions are prepared
Paris polyphylla (Hemsl.) Merr extract	0.8	Portions are prepared
			Flos Lonicerae extract	8	Portions are
Tropaeolum majus extract	5	Portions are
			Peony extract	7	Portions are prepared
Flos Lonicerae extract	8	Portions are

The skin care product additive comprises the following components:

components	Content/%
		Natural extract	38.8
Butanediol	25
		Glycerol	8
Sorbitol	5
		Hydroxyacetophenones	1
Water (W)	Balance of

Example 4

The natural extract comprises the following components:

safflower extract	3	Portions are
			Albizzia julibrissin extract	8	Portions are
Paris polyphylla (Hemsl.) Merr extract	1	Portions are
			Flos Lonicerae extract	4	Portions are
Tropaeolum majus extract	3	Portions are
			Peony extract	8	Portions are
Flos Lonicerae extract	7	Portions are

The skin care product additive comprises the following components:

components	Content/%
		Natural extract	34
Butanediol	20
		Glycerol	10
Sorbitol	5
		Hydroxyacetophenones	0.6
Water (W)	Balance of

Example 5

The natural extract comprises the following components:

safflower extract	5.5	Portions are prepared
			Albizzia julibrissin flower extract	5.5	Portions are
Paris polyphylla Smith extract	0.8	Portions are prepared
			Flos Lonicerae extract	5.5	Portions are prepared
Tropaeolum majus extract	5.5	Portions are prepared
			Peony extract	5.5	Portions are prepared
Baijin flower extract	5.5	Portions are

The skin care product additive comprises the following components:

components	Content/%)
		Natural extract	33.8
Butanediol	25
		Glycerol	8
Sorbitol	7
		Hydroxyacetophenones	0.4
Water (W)	Balance of

Comparative example 1:

the same as example 2, except that the amount of the safflower extract was adjusted to 1 part.

Comparative example 2:

the same as example 2, except that the amount of the safflower extract is adjusted to 10 parts.

Further, in order to better illustrate the advantages of the invention, the safety and efficacy of the composition obtained by the invention are tested and analyzed by adopting a specific cosmetic efficacy evaluation method aiming at sensitive skin series cosmetics, and the detection results are as follows:

skin irritation replacement test:

the stimulation of the skin care product to the skin is simulated and tested by adopting a chick embryo chorioallantoic membrane test, and the specific test method is as follows:

the negative control sample is selected from normal saline and is used for washing and negative control after the action of the test object;

a sample to be tested: example 2, add purified water to dilute to 3v/v%.

And taking out the chick embryo from the incubator, placing the chick embryo on a self-made egg rack with the air chamber end upward, after opening the air chamber, wetting the eggshell membrane with a small amount of normal saline, absorbing the normal saline, and carefully removing the inner membrane by using bent forceps to ensure that the vascular membrane is not damaged. The chorioallantoic membrane (CAM) is selected for its good integrity and suitability for testing.

Different samples are rolled back to the CAM respectively, and the phenomenon of intimal vessels is observed for 1-5 min.

The test result shows that the blood vessels have no phenomena of bleeding, hemolysis or coagulation and the like after the negative control sample and the sample to be tested are dripped for 5min, and the shape and distribution of the intimal blood vessels before and after the dripping of the sample are basically unchanged. The sample to be tested has no irritation to human skin basically and is mild.

Sensitive skin improvement experiment:

sensitive skin volunteers were recruited to request an age between 18 and 40 years, a sensitive skin or an allergic (redness, itching) condition of the face. If the face has red blood streak, the severity of the red blood streak is scored according to the following criteria:

0 is divided into smooth surface skin, no red blood streak, no pain and itch, good elasticity and basically normal skin color.

1, the part of the skin is slightly different from normal skin in appearance, is basically flush with the surrounding skin and is slightly red or white;

2 divided into slightly red blood and light color

3, the color is red with obvious red blood filaments and stabbing pain;

4, there are many obvious red blood filaments, which are gathered into lumps or pieces, and the color is dark and dark, and there are burning pain and itching feeling.

A total of 60 people were selected, 48 women, 12 men, and 3 groups of women and men were randomly and equally divided, and the skin care product of example 2 was used in the test group, and the skin care product of comparative example 1 or comparative example 2 was used in the control group. Scoring tests were performed before use (day 0), 7 days after use, and 14 days, respectively.

A sample to be tested: example 2, comparative example 1 and comparative example 2 were diluted to 3v/v% with water.

Evaluation criteria for effects:

the odor was scored according to subjective personal perception, wherein:

and 4, dividing: the smell is elegant, is pleasant and relaxed, and is expected to be continuously used next time;

and 3, dividing: the smell is light and elegant, and the product is expected to be used frequently;

and 2, dividing: the smell is acceptable, and the use is not influenced;

1 minute: the smell is general and is barely acceptable;

0 minute: has peculiar smell and is not accepted.

The using method comprises the following steps:

after the face is cleaned, a proper amount of samples are uniformly smeared on the face once in the morning and at night, other skin care products are not used in the morning and at night, and long-time solarization is avoided.

The evaluation results were as follows:

TABLE 1 evaluation results of odor of product

Scoring	Example 2	Comparative example 1	Comparative example 2
				4	18	8	3
3	2	6	6
				2	0	6	10
1	0	0	1
				0	0	0	0

The scoring result shows that the smell of the product is easily accepted by people, the product can give a pleasant feeling and relieve stress, the comparative example 1 can be generally accepted by most people, and the comparative example 2 is poor in acceptance degree.

TABLE 2 improvement of sensitive skin-redness

The scoring results show that the product of the invention is effective in improving the red blood streak condition, while comparative example 1 and comparative example 2 have a certain improvement effect, but are not obvious.

The volunteers of the product of the invention subsequently feed back further, and about 1 week after stopping using the product of the invention, the facial skin is naturally moist and has no rebound phenomenon. While with the volunteer of comparative example 1, rebound occurred about 1 day after feedback was discontinued. Using the volunteer of comparative example 2, rebound occurred about 2 days after the feedback was discontinued.

The foregoing is a more detailed description of the invention and is not to be taken in a limiting sense. It will be apparent to those skilled in the art that various modifications, additions and substitutions can be made without departing from the spirit and scope of the invention.

Claims (8)

1. A natural extract characterized by: the active ingredients of the composition comprise the following raw materials: the active ingredients are water extracts of raw materials, the water extracts are extracted by a micro-jet method, and the natural extracts comprise the following components in percentage by mass: 3 to 8 parts of safflower extract, 3 to 8 parts of albizia flower extract, 0.5 to 1.0 part of paris polyphylla extract, 3 to 8 parts of lonicera confusa extract, 3 to 8 parts of tropaeolum majus extract, 3 to 8 parts of peony flower extract and 3 to 8 parts of polygala bailii flower extract.

2. The skin care product additive comprises auxiliary materials and active ingredients, and is characterized in that: the active ingredient is the natural extract of claim 1, and the adjuvants comprise water, alcohol and p-hydroxyacetophenone.

3. The skin care additive according to claim 2, characterized in that: the weight composition is as follows: 30 to 40 percent of active component, 20 to 30 percent of butanediol, 5 to 10 percent of glycerin, 5 to 10 percent of sorbitol, 0.2 to 1.0 percent of hydroxyacetophenone and a proper amount of water.

4. The composition for improving the skin quality comprises auxiliary materials and functional components, and is characterized in that: the efficacy ingredient comprises the skin care additive of claim 2 or 3.

5. The composition of claim 4, wherein: the mass addition amount of the skin care product additive is 1.0-5.0%.

6. The composition of claim 4, wherein: the composition is a skin care product for skin care.

7. The composition of claim 6, wherein: the composition is cream, lotion, aqua, essence, gel, facial mask, or washing and cleaning skin care products.

8. The application of the natural extract in preparing the skin improver is characterized in that: the natural extract is as defined in claim 1.