CN109674710A - A kind of composite vegetables extractive and its application with antiallergic Red blood streak dispelling - Google Patents

A kind of composite vegetables extractive and its application with antiallergic Red blood streak dispelling Download PDF

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Publication number
CN109674710A
CN109674710A CN201910155355.0A CN201910155355A CN109674710A CN 109674710 A CN109674710 A CN 109674710A CN 201910155355 A CN201910155355 A CN 201910155355A CN 109674710 A CN109674710 A CN 109674710A
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Prior art keywords
extract
parts
antiallergic
red blood
skin
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CN201910155355.0A
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Inventor
张英娥
张仲福
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Guangzhou Fuyu Long Chemical Technology Co Ltd
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Guangzhou Fuyu Long Chemical Technology Co Ltd
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Priority to CN201910155355.0A priority Critical patent/CN109674710A/en
Publication of CN109674710A publication Critical patent/CN109674710A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention has the composite vegetables extractive of antiallergic Red blood streak dispelling, it is made of licorice root extract, both A. absinthium extract, ginkgo biloba p.e, Gotu Kola P.E, blueberry extract, rose extract, the effective component cooperation of each Plant Extracts, its effect is set to perform to maximum effect, it promotes blood circulation, improves capillary microcirculation, releive and calm skin, the erythema and red capillary symptom for mitigating skin long-term accumulated keep skin spontaneous recovery healthy.Clinical data is shown: compound plant extract of the present invention has significant vascular repair effect, and contraction and the vasodilation abilities of blood vessel can be improved, and has reparation and desalination effect well, total effective rate 86.25% for various types of erythema and red capillary disease.

Description

A kind of composite vegetables extractive and its application with antiallergic Red blood streak dispelling
Technical field
The present invention relates to a kind of composite vegetables extractives for antiallergic Red blood streak dispelling, mainly as active constituent for making Standby function skin care item.
Background technique
Skin be safeguard human life and health important component, be the first barrier of body, directly with the external world Contact, is highly prone to the influence of environmental factor and causes to damage.In recent years, since atmosphere pollution, all types of industries additive are abused And the reasons such as variation of people's life habit, cause the crowd of the high sensitiveness of skin to increase year by year, occur easily it is red, swollen, Heat, pain, itch, the phenomena of cutaneous irritation such as bits of peel have become influences people's appearance and a healthy big factor.
Red capillary is mainly shown as skin capillary vascular expansion, is lowly caused by cutaneous immunisation.The common formation of red capillary The reason is that cutin is impaired, capillary loses the natural protection of cuticula, to be stimulated for a long time by external environment, leads to blood Enlargement of pipe, is damaged and is formed silting.Treating red capillary most importantly improves the elasticity of facial capillary, restores blood vessel Normal contraction and diastolic function reduce vasopermeability.Current red capillary treatment method is broadly divided into living cells therapy, and physics is controlled It treats, chemotherapy.Living cells therapy is emerging treatment method in recent years, and effect is satisfactory, is not easy to rebound, and gives red capillary Patient repairs and brings new hope.Physical therapy is using specific wavelength to skin exposure, and red capillary is to specific wavelength It absorbs, to achieve the effect that dispel.Chemical method mainly uses chemicals (or cosmetics), the characteristics of according to red capillary And specific absorption, to dispel red capillary.Chemicals mainly reduces vasopermeability.The skin of red capillary is generally also quicker Sense, also can choose some products with antiallergic sense.
Summary of the invention
The object of the present invention is to provide a kind of composite vegetables extractives with antiallergic Red blood streak dispelling;
It is a further object of the present invention to provide application of the compound plant extract in preparation antiallergic Red blood streak dispelling skin care item.
The present invention has the composite vegetables extractive of antiallergic Red blood streak dispelling, is extracted by licorice root extract, both A. absinthium Object, ginkgo biloba p.e, Gotu Kola P.E, blueberry extract, rose extract composition.
Licorice, sweet in flavor, heat-clearing, alleviate pain swollen sore, and can coordinating the drug actions of a prescription;There are also anti-inflammatory, anti-allergic effects for Radix Glycyrrhizae;Radix Glycyrrhizae In contain glycyrrhizin, be a kind of compound of similar hormone, it facilitate balance the intracorporal hormone-content of women.Studies have shown that Licorice mainly contains the triterpenoid saponin of glycyrrhizic acid series and the flavone compound of structure type multiplicity, such as light Radix Glycyrrhizae Plain T, glabridin, licoricidin, licoisoflavone A, licoisoflavanone B, Semilicoisoflavone B, onocerin, glycyrrhizin Deng, therefore there is antioxygenic activity, very strong sterilization, depigmentation of skin, the effect for desalinating acne print.
Both A. absinthium is the plant of composite family artemisia.Alias: wormwood (South of Jiangsu Province seed plant handbook), absinth, Artemisia santonica, Beer wormwood artemisia.Bitter, it is cold in nature.Leaf and capitulum contain bitter principle, and ingredient is interior lipoid substance and diterpene product.Herb enters Medicine has the benefits of anti-inflammatory, stomach invigorating, expelling parasite.
Ginkgo leaf, it is sweet in flavor, property is bitter, there is activating microcirculation and removing stasis medicinal, remove obstruction in channels to relieve pain, the effect of astringing lung-QI relievings asthma, changes turbid lipid-loweringing.Ginkgo leaf In containing shikimic acid, ginkegetin, isoginkgetin, sterol etc., for treating hypertension and coronary heart diseases and angina pectoris, brain The excessively high illness of vasopasm, serum cholesterol has certain effect.Ginkgo leaf eliminates the deposition ingredient on vascular wall, improves blood Liquid stream denaturation, promotes the deformability of red blood cell, reduces blood viscosity, keeps blood flow unobstructed.
Centella is the herb of umbelliferae centella.Toil is trembled with fear;With clearing heat and promoting diuresis, the effect of subdhing swelling and detoxicating. Modern medicine study shows that asiaticosid can inhibit collagenous fibres, have the function of inhibit proliferation of fibrous tissue, activating microcirculation and removing stasis medicinal, Antibacterial and anti-inflammation functions.In addition, centella can promote skin growth, local leukocytosis, connective tissue rete vasculosum increases, mucus Secretion increases, and fur hyperplasia accelerates, and plays the role of inhibiting skin ulcer.
Blueberry is a kind of very high fruit of nutritive value.Pulp is rich in vitamin abundant, protein and minerals etc. Nutrient, wherein the anthocyanin pigments of unique preciousness have extensive biological activity in blueberry, belong to pure natural resist Oxidation, aging nutritional supplement.Blueberry blueberry SOD rich in and pterostilbene, and SOD is free radical important in organism Scavenger, main function are exclusively to remove the ultra-oxygen anion free radical generated in biological oxidation;Pterostilbene equally has Have good anti-oxidant, anti-inflammatory and other effects.
Rose contains 300 various chemical components, such as alcohol of fragrance, aldehyde, fatty acid, phenol and oil and rouge containing essence, often The promoting blood circulation of having a respite with the awake stomach of soft liver in rose product is eaten, beautifying face and moistering lotion makes us refreshing refreshing.The flower and root that rose just opens can be used as medicine, and have Qi-regulating, promoting blood circulation, Thyme Extract.There are also the effects of balancing hormones for it, facilitate the beauty and health of women.
In compound plant extract of the present invention, the effective component cooperation of each Plant Extracts plays its effect It to maximum effect, promotes blood circulation, improves capillary microcirculation, releive and calm skin, mitigate the erythema of skin long-term accumulated With red capillary symptom, keep skin spontaneous recovery healthy.
The each component of compound plant extract is made by conventional extraction process, and low temperature extraction can also be passed through Technique obtains.It is matched with calm skin effect, each extract components by following parts by weight to obtain preferably to releive: sweet 14 ~ 20 parts of grass roots extract, 10 ~ 15 parts of both A. absinthium extract, 4 ~ 8 parts of ginkgo biloba p.e, 4 ~ 8 parts of Gotu Kola P.E, 4 ~ 8 parts of blueberry extract, 4 ~ 8 parts of rose extract.
Optimum ratio: 15 ~ 18 parts of licorice root extract, 10 ~ 12 parts of both A. absinthium extract, 6 ~ 7 parts of ginkgo biloba p.e, 6 ~ 7 parts of Gotu Kola P.E, 6 ~ 7 parts of blueberry extract, 6 ~ 7 parts of rose extract.
Optimum proportioning: 18 parts of licorice root extract, both A. absinthium extract 12,6 parts of ginkgo biloba p.e, centella are extracted 6 parts of object, 5 parts of blueberry extract, 5 parts of rose extract.
The product specification of compound plant extract is as follows:
Appearance: light yellow clear liquid
Smell: slight characteristic odor
Specific gravity (20 °C): 1.100-1.130
PH value (25 °C): 4.0-7.0
Polyoses content: Brix %
Total number of bacteria: < 100CFU/ml
Saccharomycete and mould: < 10CFU/ml
Mercury: < 1mg/Kg
Arsenic: < 2mg/Kg
Lead: < 5mg/Kg
Packing specification: 5Kg/ barrels;10Kg/ barrels;25Kg/ barrels
Preservation condition: the dark container sealing of product is protected from light and is housed in environment that is dry, divulging information, and 15 DEG C ~ 25 DEG C of temperature.It is wrapping Install it is whole, without under holding conditions as defined in breaking seal and meeting, shelf life of products 24 months.
Studies have shown that compound plant extract of the invention have effects that it is following:
1, there is significant vascular repair effect, contraction and the vasodilation abilities of blood vessel can be improved, reduce the permeability of vascular wall, Red capillary can thus be improved, mitigate the erythema and red capillary symptom of skin long-term accumulated;
2, moisturizing and sunburn, the effect of calm skin are pacified, keeps skin smooth fine and smooth;
3, strength is anti-oxidant, to free radical resisting, prevents skin aging;
4, anti-inflammatory to pacify, skin complexion and glossy degree are promoted, keeps skin whitening soft.
Therefore, compound plant extract that can be of the invention is active constituent, is applied to prepare functional skin-protection product, such as Essence, lotion, cream, facial mask, toner etc..In order to reach good capillary microcirculation, the effect releived with calm skin, Compound plant extract additive amount in skin care item is that mass fraction is calculated as 1.0 ~ 5.0wt.%.
Compound plant extract of the present invention is treated below by clinical data, improves the effect of erythema and red capillary symptom It is described further.
1, clinical observation object
Typical erythema and red capillary patient with sympotoms 80, women, the age was at 15 ~ 40 years old.
2, clinical symptoms
Face occurs netted or sheet of red, and face is redder when supercooling, overheat, excited, temperature suddenly change.
3, treatment method
It is the cream of main component preparation with compound plant extract of the present invention.Usage and dosage: it is respectively smeared after cleaning skin sooner or later Once, it persistently smears one month.
4, criterion of therapeutical effect
Recovery from illness: erythema, red capillary symptom are repaired completely, and entire face skin quality is smooth, fine and smooth.It is effective: erythema and red capillary Symptom is obviously thin out, and entire face ratio of skin tone is more uniform, and good luster is smooth, but has erythema and red capillary symptom residual.Nothing Effect: erythema and red capillary symptom are not improved.
5, treatment results
Recovery from illness: 32, effective 37, invalid 11.Total effective rate is 86.25%.
Above-mentioned clinical data is shown: compound plant extract of the present invention has significant vascular repair effect, can be improved The contraction of blood vessel and vasodilation abilities have reparation and desalination effect well for various types of erythema and red capillary disease.
Specific embodiment
Make furtherly below by raw material proportioning, preparation process and instructions of taking of the specific embodiment to drug of the present invention It is bright.
The preparation of embodiment 1, lotion
Respectively by licorice, both A. absinthium, ginkgo leaf, centella, blueberry, rose carry out sterilization treatment, deionized water are added and makees Low temperature extraction is carried out for solvent (plant: deionized water=1:40 weight ratio), glycerol is added as solvent in centrifugation slagging-off Carry out multistage UF membrane, concentration, obtain licorice root extract, both A. absinthium extract, ginkgo biloba p.e, Gotu Kola P.E, Blueberry extract, rose extract.
By 18 parts of licorice root extract, both A. absinthium extract 12,6 parts of ginkgo biloba p.e, 6 parts of Gotu Kola P.E, 5 parts of blueberry extract, 5 parts of rose extract are formulated, and obtain compound plant extract.
Using compound plant extract as main active component (additive amount of compound plant extract is 10 wt.%), use The customary adjuvant and technique for producing lotion are prepared into product emulsion.
The preparation of embodiment 2, face cream
Licorice root extract, both A. absinthium extract, ginkgo biloba p.e, Gotu Kola P.E, blueberry extract, rose are extracted The preparation of object is the same as embodiment 1.
By 14 parts of licorice root extract, 10 parts of both A. absinthium extract, 4 parts of ginkgo biloba p.e, Gotu Kola P.E 4 Part, 4 parts of blueberry extract, 4 parts of rose extract are formulated, and compound plant extract is obtained.
Using compound plant extract as main active component (additive amount of compound plant extract is 10 wt.%), use The customary adjuvant and technique for producing face cream are prepared into face cream product.
The preparation of embodiment 3, facial mask
Licorice root extract, both A. absinthium extract, ginkgo biloba p.e, Gotu Kola P.E, blueberry extract, rose are extracted The preparation of object is the same as embodiment 1.
By 20 parts of licorice root extract, 15 parts of both A. absinthium extract, 8 parts of ginkgo biloba p.e, Gotu Kola P.E 8 Part, 8 parts of blueberry extract, 8 parts of rose extract are formulated, and compound plant extract is obtained.
Using compound plant extract as main active component (additive amount of compound plant extract is 10 wt.%), use The customary adjuvant and technique for producing facial mask are prepared into mask product.
The preparation of embodiment 4, toner
Licorice root extract, both A. absinthium extract, ginkgo biloba p.e, Gotu Kola P.E, blueberry extract, rose are extracted The preparation of object is the same as embodiment 1.
By 15 parts of licorice root extract, 10 parts of both A. absinthium extract, 6 parts of ginkgo biloba p.e, Gotu Kola P.E 6 Part, 6 parts of blueberry extract, 6 parts of rose extract are formulated, and compound plant extract is obtained.
Using compound plant extract as main active component (additive amount of compound plant extract is 10 wt.%), use The customary adjuvant and technique for producing toner are prepared into skin toner aquatic products.
The preparation of embodiment 5, Essence
Licorice root extract, both A. absinthium extract, ginkgo biloba p.e, Gotu Kola P.E, blueberry extract, rose are extracted The preparation of object is the same as embodiment 1.
By 18 parts of licorice root extract, 12 parts of both A. absinthium extract, 7 parts of ginkgo biloba p.e, Gotu Kola P.E 6 Part, 7 parts of blueberry extract, 7 parts of rose extract are formulated, and compound plant extract is obtained.
Using compound plant extract as main active component (additive amount of compound plant extract is 10 wt.%), use The customary adjuvant and technique for producing Essence are prepared into essence liquid product.

Claims (9)

1. a kind of composite vegetables extractive with antiallergic Red blood streak dispelling is by licorice root extract, both A. absinthium extract, silver Apricot leaf extract, Gotu Kola P.E, blueberry extract, rose extract composition.
2. a kind of composite vegetables extractive with antiallergic Red blood streak dispelling as described in claim 1, it is characterised in that: each extract Component is matched by following parts by weight: 14 ~ 20 parts of licorice root extract, 10 ~ 15 parts of both A. absinthium extract, ginkgo leaf extract 4 ~ 8 parts of object, 4 ~ 8 parts of Gotu Kola P.E, 4 ~ 8 parts of blueberry extract, 4 ~ 8 parts of rose extract.
3. a kind of composite vegetables extractive with antiallergic Red blood streak dispelling as described in claim 1, it is characterised in that: each extract Component is matched by following parts by weight: 15 ~ 18 parts of licorice root extract, 10 ~ 12 parts of both A. absinthium extract, ginkgo leaf extract 6 ~ 7 parts of object, 6 ~ 7 parts of Gotu Kola P.E, 6 ~ 7 parts of blueberry extract, 6 ~ 7 parts of rose extract.
4. a kind of composite vegetables extractive with antiallergic Red blood streak dispelling as described in claim 1, it is characterised in that: each extract Component is matched by following parts by weight: 18 parts of licorice root extract, both A. absinthium extract 12,6 parts of ginkgo biloba p.e, product Snow careless 6 parts of extract, 5 parts of blueberry extract, 5 parts of rose extract.
5. a kind of composite vegetables extractive with antiallergic Red blood streak dispelling as described in claim 1, it is characterised in that: compound plant The product specification of extract is as follows:
Appearance: light yellow clear liquid
Smell: slight characteristic odor
Specific gravity (20 °C): 1.100-1.130
PH value (25 °C): 4.0-7.0
Polyoses content: Brix %
Total number of bacteria: < 100CFU/ml
Saccharomycete and mould: < 10CFU/ml
Mercury: < 1mg/Kg
Arsenic: < 2mg/Kg
Lead: < 5mg/Kg.
6. the composite vegetables extractive with antiallergic Red blood streak dispelling is for producing functional skin-protection product as described in claim 1.
7. the composite vegetables extractive with antiallergic Red blood streak dispelling is used to produce functional skin-protection product as described in claim 1, It is characterized by: using compound plant extract as active constituent, using the customary adjuvant and technique for producing functional skin-protection product It is prepared into skin-protection product.
8. the composite vegetables extractive with antiallergic Red blood streak dispelling is used to produce functional skin-protection product as claimed in claim 7, It is characterized by: compound plant extract additive amount in skin care item is that mass fraction is calculated as 1.0 ~ 5.0wt.%.
9. the composite vegetables extractive as described in claim 7 or 8 with antiallergic Red blood streak dispelling is produced for producing functional skin care Product, it is characterised in that: skin care item are essence, lotion, cream, facial mask, toner.
CN201910155355.0A 2019-03-01 2019-03-01 A kind of composite vegetables extractive and its application with antiallergic Red blood streak dispelling Pending CN109674710A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114010571A (en) * 2021-12-06 2022-02-08 广州市悦锐生物科技有限公司 Natural extract for soothing skin and improving skin quality and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309251A (en) * 2016-10-14 2017-01-11 广东丸美生物技术股份有限公司 Herba centellae extract with anti-inflammation and anti-sensitivity effects and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309251A (en) * 2016-10-14 2017-01-11 广东丸美生物技术股份有限公司 Herba centellae extract with anti-inflammation and anti-sensitivity effects and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
开心农场: "上海舜拓", 《HTTPS://MAX.BOOK118.COM/HTML/2017/》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114010571A (en) * 2021-12-06 2022-02-08 广州市悦锐生物科技有限公司 Natural extract for soothing skin and improving skin quality and application thereof

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