CN115006336B - Plant shampoo capable of preventing hair loss, strengthening hair, removing dandruff and relieving itching and preparation method thereof - Google Patents

Plant shampoo capable of preventing hair loss, strengthening hair, removing dandruff and relieving itching and preparation method thereof Download PDF

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CN115006336B
CN115006336B CN202210798060.7A CN202210798060A CN115006336B CN 115006336 B CN115006336 B CN 115006336B CN 202210798060 A CN202210798060 A CN 202210798060A CN 115006336 B CN115006336 B CN 115006336B
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plant
hair
sodium
ginseng
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CN115006336A (en
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齐彬
齐行铎
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Jinan Yufa Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9761Cupressaceae [Cypress family], e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention provides a plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching and a preparation method thereof, and relates to the field of washing and caring products, wherein the plant shampoo comprises the following raw materials: water, plant composition extract, C12-15 alkyl polyether sodium sulfate, cocamide DEA, sodium laurylsulfate, cocamidopropyl betaine, sodium chloride, PCA sodium, cocamidopropyl PG-dimethyl ammonium chloride phosphate, piroctone olamine, essence, polyquaternium-10, citric acid, EDTA disodium, and pinocembron. The plant shampoo prepared by compounding the raw materials is safe and mild, and has various effects of preventing hair loss, strengthening hair, removing dandruff, relieving itching and the like.

Description

Plant shampoo capable of preventing hair loss, strengthening hair, removing dandruff and relieving itching and preparation method thereof
Technical Field
The invention relates to the field of washing and caring products, in particular to an anti-hair loss and hair-care plant shampoo capable of removing dandruff and relieving itching and a preparation method thereof.
Background
The shampoo is one of common washing and caring products, can be used for cleaning hair, oil and sweat scale on scalp, dust, microorganism, etc., and has various effects of preventing alopecia, whitening, promoting hair growth, relieving itching, etc. Shampoo is generally classified into common shampoo, anti-dandruff and antipruritic shampoo, shampoo for washing and dyeing, and the like according to functions, so far, shampoo with various effects and safety is the direction of current important research.
For example: patent CN103550108B discloses a hair nourishing and damage repairing shampoo, which comprises the following components in percentage by mass: 0.5% -5.0% of medicinal plant extract, 0.1% -3.0% of keratin, 8% -12% of surfactant, 4% -8% of softening conditioner, 0.3% -1.5% of acid-base regulator, 1% -2% of thickener, 0.5% -2.0% of pearling agent, 0.1% -0.4% of salt and 68% -80% of deionized water, wherein the medicinal plant extract comprises the following components: the shampoo can repair damaged hair quickly and efficiently, avoid the non-refreshing feel during and after use, simplify the formula and reduce the cost.
Patent CN108685779a discloses a traditional Chinese medicine shampoo for curing hair, which contains traditional Chinese medicine components prepared from the following raw materials: radix rehmanniae Preparata, rhizoma Polygonati, semen Sojae Atricolor, fructus Zizaniae Caduciflorae, semen Sesami, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, ginseng radix, radix Angelicae Dahuricae, folium Mori, folium Artemisiae Argyi, medulla Tetrapanacis, cistanchis herba, mori fructus, fructus Lycii, galla chinensis, herba Rosmarini officinalis, herba Chelidonii, herba Portulacae, herba Senecionis Scandentis, ecliptae herba, herba Siegesbeckiae herba, fructus Cnidii, semen Celosiae, folum Ilicis, folium Pini, tea bran, fructus Lipuidambaris, fructus Gleditsiae Abnormalis, folium Platycladi, radix Hedyotis, folium Mori, rhizoma Alpiniae Officinarum, herba Lycopodii, and Polygoni Multiflori radix. The shampoo provided by the invention can moisten scalp, improve the activity of hair and scalp cells, can firmly root hair, prevent and treat alopecia, and has a good hair-fixing effect.
Patent CN110755592A discloses a traditional Chinese medicine composition for promoting hair growth and nourishing hair, and a preparation method and application thereof, and the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 30-50 parts of cacumen biotae, 20-40 parts of Chinese honeylocust fruit, 20-40 parts of fleece-flower root, 10-20 parts of white mulberry root-bark, 10-20 parts of dried ginger, 5-18 parts of black sesame, 5-18 parts of red sage root, 2-10 parts of Chinese angelica, 2-10 parts of medlar, 1-8 parts of semen cuscutae, 1-8 parts of achyranthes root, 1-5 parts of poria cocos, 1-5 parts of fructus psoraleae and 1-5 parts of ginger. The product of the invention is safe and effective, has no side effect, reduces the damage to human body, can stimulate scalp, accelerate the blood circulation of head, activate atrophic hair follicle, rebuild the hair follicle nutrition supply system, and has obvious curative effect on various alopecia and poliosis by externally coating the alopecia and poliosis parts.
However, most of the current shampoos still have the problems of limited efficacy, strong irritation or complicated preparation method, and aiming at the problems, it is necessary to find a safe, mild and simple-preparation shampoo with the multiple effects of preventing hair loss, strengthening hair, removing dandruff and relieving itching.
Disclosure of Invention
Aiming at the problems existing in the prior art, the invention provides the plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching and the preparation method thereof.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
the invention provides a plant shampoo, which comprises the following raw materials: water, plant composition extract, C12-15 alkyl polyether sodium sulfate, cocamide DEA, sodium laurylsulfate, cocamidopropyl betaine, sodium chloride, PCA sodium, cocamidopropyl PG-dimethyl ammonium chloride phosphate, piroctone olamine, essence, polyquaternium-10, citric acid, EDTA disodium, and pinocembron.
Further, the plant shampoo comprises the following components in percentage by weight: 57.6% of water, 20% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamidide DEA, 3% of sodium lauryl sulfate, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon.
Preferably, the plant shampoo comprises the following components in percentage by weight: 47.6% of water, 30% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamidide DEA, 3% of lauryl sulfate sodium, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon.
Further, the plant composition extract comprises the following raw materials: polygonum multiflorum, ligusticum wallichii, black sesame, chinese angelica, ginseng, spatholobus stem, cacumen biotae, chinese honeylocust spine, cistanche, liquorice, dried ginger, fructus viticis, mulberry, aloe vera gel, eclipta alba, purslane, magnolia officinalis, mulberry leaf, garden balsam stem, dandelion, cordyceps militaris, leech, pseudo-ginseng, hippocampus and cordyceps sinensis.
Preferably, the plant composition extract comprises the following raw materials in percentage by weight: 10-20 parts of polygonum multiflorum, 5-15 parts of ligusticum wallichii, 5-15 parts of black sesame, 10-20 parts of angelica sinensis, 5-15 parts of ginseng, 10-20 parts of caulis spatholobi, 15-35 parts of cacumen biotae, 10-20 parts of fructus gleditsiae, 5-15 parts of cistanche, 10-30 parts of liquorice, 5-15 parts of dried ginger, 5-15 parts of fructus viticis, 10-20 parts of mulberry, 5-15 parts of aloe vera gel, 10-20 parts of eclipta alba, 10-20 parts of purslane, 10-20 parts of magnolia officinalis, 10-20 parts of mulberry leaf, 15-25 parts of garden balsam stem, 10-20 parts of dandelion, 5-10 parts of cordyceps militaris, 5-10 parts of leech, 5-10 parts of pseudo-ginseng, 5-15 parts of cordyceps sinensis and 2-5 parts of cordyceps sinensis.
Preferably, the plant composition extract comprises the following raw materials in percentage by weight: 20 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 10 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 10 parts of pseudo-ginseng, 10 parts of sea horse and 4 parts of cordyceps sinensis.
Further, the plant composition extract comprises the following raw materials in percentage by weight: 15 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 10 parts of ginseng, 10 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust fruit, 10 parts of cistanche, 20 parts of liquorice, 10 parts of dried ginger, 10 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 10 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 7 parts of pseudo-ginseng, 8 parts of sea horse, and 3 parts of cordyceps sinensis.
Further, the plant composition extract comprises the following raw materials in percentage by weight: 20 parts of fleece-flower root, 15 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 15 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 15 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 10 parts of magnolia officinalis, 15 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 8 parts of leech, 10 parts of pseudo-ginseng, 8 parts of sea horse and 2 parts of cordyceps sinensis.
Further, the weight ratio of fructus viticis to mulberry to eclipta and dandelion is 5-15:10-20:10-20:10-20, preferably 15:20:20:15 or 10:20:20:15.
Further, the weight ratio of the cordyceps militaris to the leech to the pseudo-ginseng to the sea horse to the cordyceps sinensis is 5-10:5-10:5-10:5-15:2-5. Preferably 10:10:10:10:4 or 10:10:7:8:3 or 10:8:10:8:2.
The invention also provides a preparation method of the plant shampoo, which comprises the following steps:
(1) Preparing plant composition extract for later use;
(2) Dispersing essence with water, stirring, and heating;
(3) Continuously adding C12-15 sodium alkyl alcohol polyether sulfate, sodium lauryl sulfate, plant combination extract, sodium chloride and polyquaternium-10, stirring, continuously heating, and stirring;
(4) Cooling, adding cocamide DEA, cocamidopropyl betaine, sodium PCA, cocamidopropyl PG-dimethyl ammonium chloride phosphate, piroctone olamine, citric acid, EDTA disodium, and pinocembron, stirring, homogenizing, and filtering.
In some specific embodiments, the preparation method of the plant shampoo comprises the following steps:
(1) Preparing plant composite extract, weighing the initial herbal materials according to a proportion, cleaning with water, adding into an extraction device, adding water according to a proportion, boiling, refluxing and extracting for 2 hours, and allowing proper extension. Cooling, filtering, and supplementing water loss for standby.
(2) Checking and closing a discharge valve of the emulsifying pot. Accurately weighing essence and water, and dispersing the essence with proper amount of water before adding the essence into an emulsifying pot. Then all the materials are added into an emulsifying pot, stirring is started, and the rotating speed is set to 15 revolutions per minute.
(3) The steam generator was turned on to raise the raw water temperature to 55 ℃.
(4) The stirring was turned off. Accurately weighing sodium C12-15 alkyl alcohol polyether sulfate, sodium laurylsulfate, plant combination extract, sodium chloride and polyquaternium-10, and adding into emulsifying pot.
(5) Closing the opening of the locking emulsifying tank, starting stirring, and setting the stirring rotating speed to 15 revolutions per minute.
(6) The steam generator was turned on and turned off when the temperature of the material was raised to 85 ℃, at which time preheating increased the material temperature and maintained at 85-95 ℃, maintaining the temperature in this interval, maintaining stirring for 1 hour, and allowing proper extension.
(7) And closing the steam inlet and outlet valve and opening the cooling water inlet and outlet valve.
(8) Cooling to 50 ℃, and closing the cooling water inlet and outlet valve.
(9) The stirring was turned off and cocamidopropyl betaine, sodium PCA, cocamidopropyl PG-dimethyl ammonium chloride phosphate, piroctone olamine, citric acid, disodium EDTA, and pinocembron were weighed into an emulsifying pot.
(10) Closing the opening of the locking emulsifying tank, starting stirring, and setting the stirring rotating speed to 15 revolutions per minute. The homogenization is started, and the rotating speed is set to 1300 revolutions per minute.
(11) The homogenization time was 1 hour, and the stirring time was 1 hour. Allowing for proper extension.
(12) And (5) closing homogenizing and stirring, filtering, discharging and weighing.
(13) Standing for 12 hours, and filling.
Further, the preparation method of the plant combination extract comprises the following steps:
s1: pulverizing the plant composition, adding water, decocting, mixing the extractive solutions, and concentrating to obtain concentrated solution;
s2: mixing the concentrated solution with ethanol to obtain a plant combination solution;
s3: precipitating the plant combination liquid with ethanol, and filtering to obtain supernatant;
s4: separating ethanol in the supernatant to obtain plant composition extract.
In some embodiments, the method of preparing a plant combination extract comprises the steps of:
s1: pulverizing Polygoni Multiflori radix, rhizoma Ligustici Chuanxiong, semen Sesami Niger, radix Angelicae sinensis, ginseng radix, caulis Spatholobi, folium Platycladi, fructus Gleditsiae Abnormalis, cistanchis herba, glycyrrhrizae radix, zingiberis rhizoma, fructus Vitics Simplicifoliae, mori fructus, aloe gel, ecliptae herba, herba Portulacae, cortex Magnolia officinalis, folium Mori, herba Speranskiae Tuberculatae, herba Taraxaci, cordyceps militaris, hirudo, notoginseng radix, hippocampus, cordyceps into 120 mesh.
S2: adding water into the plant composition according to the mass ratio of 1:10, and decocting at 100 ℃ for 2 hours (timing after boiling) to obtain an extract 1 of the plant composition;
s3: adding water according to the mass ratio of 1:8, and decocting at 100deg.C for 2 hr (after boiling) to obtain extract 2 of plant composition;
s4: mixing (extract 1, extract 2, and) the secondary extract. The liquid was concentrated to a relative density of 1.16.
S5: mixing 50% -60% ethanol with the concentrated solution at normal temperature, (remarking: when mixing, pouring ethanol gently, stirring slowly and uniformly, adding ethanol amount, measuring with a meter to obtain 40% -50% ethanol-containing plant combination liquid, and obtaining 40% -50% ethanol-containing plant combination liquid. (5) 40% -50% of plant combination liquid containing ethanol is obtained. After 24h of alcohol precipitation (ethanol precipitation method, removing impurities in the extract), filtering to obtain supernatant.
S6: finally, ethanol is separated by a steam method, and the plant combination supernatant without ethanol is obtained.
The polygonum multiflorum, the blood replenishing medicine, the essence and blood replenishing, the hair blacking and retaining youthful looks, the dryness moistening and wind dispelling are used for early white hair and alopecia, which can tonify liver and kidney and nourish essence and blood, so the polygonum multiflorum can strengthen tendons and bones, blacken the hair, is an essential medicine for blacking the hair, is applied to the polygonum multiflorum as in the formula of medicine Ji Jie, is used for nourishing blood and moisturizing dryness, dispelling wind and relieving itching, can treat skin itch caused by blood deficiency and wind generation, and is applied to the polygonum multiflorum powder as in the formula of medicine Ji Jie;
ligusticum wallichii, a medicine for promoting blood circulation to remove blood stasis, can be used for treating alopecia caused by blood stasis, and the extract has an antioxidation effect, can inhibit the generation of free radicals, effectively remove oxygen free radicals, and is a skin-activating anti-aging agent;
the black sesame is a good nourishment, has the effects of tonifying liver and kidney, moistening five viscera and tonifying qi, can treat dizziness, premature graying of hair, alopecia, soreness of waist and knees, limb weakness and dry skin, and has the effects of blackening hair and caring skin.
Chinese angelica, a blood replenishing medicine, has good effects of treating white hair and alopecia caused by blood deficiency;
ginseng, a tonic, can dilate capillary vessels of the head, can increase nutrition of hair, improve toughness of hair, reduce alopecia and hair breakage, has a protective effect on damaged hair, can nourish qi and blood after hair is blood, and has records of treating alopecia in external secret aspects and Shengji general records;
caulis Spatholobi has effects of replenishing blood, promoting blood circulation, and dredging collaterals. The root is used as a medicine, has the functions of relaxing muscles and stimulating blood circulation, and also has the function of killing insects.
The Chinese arborvitae twig and hemostatic can smooth scalp to enable nutrient components to be better absorbed by hair roots, stimulate and care hair stems, prevent falling off, promote normal growth of hair, achieve the effects of preventing falling off and promoting hair growth, be used for treating alopecia, premature beard and hair Bai Benpin bitter and cold, cool blood, promote hair growth and blacken hair, treat blood heat alopecia, and have the symptoms of dry and yellow hair, soft hair quality, sparse falling off, and be used singly or be matched with polygonum multiflorum and the like when the hair is baked;
fructus Gleditsiae Abnormalis, eliminating phlegm, relieving cough, inducing resuscitation, dredging and blocking, killing parasites, and resolving hard mass. The use of fructus Gleditsiae Abnormalis for washing hair can make hair black and bright, and can repair damaged hair, because fructus Gleditsiae Abnormalis contains abundant saponins, minerals and microelements essential for hair, etc
Cistanche salsa, tonifying kidney yang, replenishing essence and blood, relaxing bowel, and the phenylallyl alcohol sugar contained in cistanche salsa is an ingredient which is not contained in other medicines. It is the most effective component for delaying aging.
Licorice root, radix Glycyrrhizae Praeparata, invigorating spleen and replenishing qi, clearing away heat and toxic materials, harmonizing the drugs, and relieving drug toxicity;
the dried ginger can relieve exterior syndrome, master skin and hair, release exterior syndrome and dispel cold, and can promote hair growth and serve as a hair accelerator;
fructus Vitics Simplicifoliae, exterior-releasing herbs, herb theory of herb (Equisetum wind-treating herbs) are used for treating alopecia, hair loss and hair loss by external application of the Mi Zhen Jing Zigao in the outer stage.
Mulberry, mori fructus, it is cold in nature, sour and sweet in taste. Enter three meridians, (heart meridian, liver meridian and kidney meridian, respectively). Has effects in nourishing yin, promoting blood production, promoting salivation, and moistening dryness. Mulberry can nourish the limbs and the bones by nourishing yin and generating blood, so that the mulberry can nourish the blood, promote the production of body fluid and moisten dryness to invigorate body fluid in vivo, and can improve the vitality of hair and enable the hair to grow.
Aloe vera gel, aloe vera contains anthraquinone compounds which absorb ultraviolet light having a wavelength of 200-290 nm, thus protecting hair from ultraviolet radiation; in addition, aloe can promote blood circulation of human body, thus promoting hair growth.
The eclipta and tonic medicine has the effects of activating the aminopeptidase, can increase the secretion of melanin and is beneficial to the prevention and treatment of white hair;
purslane, a drug for clearing heat and removing toxicity, and purslane powder of Taiping Sheng Hui Fang, are used for treating white hair caused by kidney deficiency and blood heat and wind dryness;
magnolia officinalis, bitter in flavor, flat and warm in nature, is indicated for spleen, kidney, lung and large intestine meridians. Inhibiting the activity of various pathogenic bacteria, resisting bacteria and viruses, and enhancing immunity.
Mulberry leaf, folium mori, wind-heat dispelling, lung-heat clearing, dryness moistening, liver-heat clearing and eyesight improving;
herba speranskiae tuberculatae has effects of promoting blood circulation, relieving pain, dispelling pathogenic wind, removing dampness, removing toxic substance, and promoting eruption. Herba speranskiae tuberculatae has certain effects on treating alopecia.
Dandelion, a heat-clearing and toxicity-removing medicine, wherein the medicine is carried in the compendium of materia medica and can blacken beard and hair and strengthen bones and muscles, and the medicine is considered to be capable of tonifying liver and kidney, cooling blood and blacking hair besides clearing heat and detoxicating in the medicine;
cordyceps militaris mainly has the effects of protecting lung, tonifying kidney and nourishing liver. Can improve the detoxification capacity of the liver, play a role in protecting the liver and improve the antiviral and anti-radiation capacities of the body. Skin caring, wrinkle preventing, antiaging, antibacterial, antiinflammatory, tranquilizing, blood vessel dilating, blood pressure lowering, blood sugar lowering, antifatigue, and anoxia resisting effects.
Leech, a blood-activating and stasis-removing medicine, breaks blood, removes stasis, passes through channels, promotes qi and blood to reach the vertex, nourishes head skin and hair, and blackens beard and hair;
notoginseng radix, blood circulation promoting medicine, has effects of promoting microcirculation, promoting synthesis of new cells, and relieving inflammation;
hippocampus is sweet and salty in nature, slightly warm in nature, entering liver and kidney yin. Has effects of strengthening body constitution, invigorating kidney, supporting yang, dispelling pathogenic wind, activating collaterals, relieving inflammation and pain, relieving cough and asthma, and tranquilizing.
Cordyceps sinensis has effects of tonifying, invigorating kidney and liver, and promoting penetration, and can be used as skin-activating antiaging agent.
Further, the plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching is suitable for people: mainly has the problems of alopecia, thin and thin hair, dandruff, itching and normal healthy people.
Further, the usage of the plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching is as follows:
1. the hair is wetted with warm water. Cold water stimulates the scalp and hot water damages the hair, so warm water is often the best choice. People with long hair can gather all hair to the top of the head, so that the shampoo can be conveniently smeared.
2. After the hair and the scalp are sufficiently moistened, a proper amount of plant shampoo capable of preventing hair from falling, removing dandruff and relieving itching is taken and uniformly smeared on the scalp and the hair roots after the palm is foamed. The plant shampoo foam for preventing hair loss, strengthening hair, removing dandruff and relieving itching is particularly dense and fine.
3. Then gently rub the hair and scalp to make an omnibearing SPA for the head. This step is primarily intended to aid in the cleaning of scalp grease, dandruff and other dirt. The formula of the plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching has strong and mild cleaning capability, and the plant composition extract is added into the shampoo, so that the dandruff is removed, the itching feeling of the head can be relieved, and the irritation to the scalp is reduced.
4. After three and five minutes of massage, the water can be used for washing again. Care must be taken to rinse the shampoo clean. Although shampoos contain many nutrients that are beneficial to the scalp and hair, such as: probiotic fermented essence of head flora and biota orientalis leaf, zingiberis rhizoma plant extract, etc. for strengthening hair are balanced. However, these active ingredients have sufficiently nourished the scalp during the previous massage.
5. After washing with warm water, the washing can be repeated with cold water. As doing so can help secure the hair roots, consolidate the scalp. And accelerates the absorption of previous nutrients by the hair.
6. After the whole process is finished, the towel can be used for gently wiping the hair, and the hair is waited for naturally airing. If a blower is to be used, the cold air is selected as much as possible. Ordinary hair dryers can easily damage hair and the hair being blown out can be particularly frizzy.
The invention has the technical effects that:
compared with the prior art, the invention provides the plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching and the preparation method thereof, and has the following advantages:
1. the invention has no toxic or side effect, quick response and obvious effect.
2. Has multiple effects of removing dandruff, diminishing inflammation, relieving itching, nourishing hair follicle, repairing hair quality, etc.
Besides the effects of preventing alopecia and strengthening hair, the hair follicle repairing agent has multiple effects of regulating the sebaceous gland to secrete grease gradually and normally, removing dandruff, diminishing inflammation and relieving itching, nourishing hair follicle and repairing hair quality, and the like, so that various damaged hair gradually recover toughness, blacken and glossy, moisten and smooth. For seborrheic dermatitis of scalp, the scalp can be healed generally for several times. The plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching realizes the purpose of treating both principal and secondary aspect of disease, is compatible and promoted, has unexpected nursing function on scalp, and enables hair follicles to be in a healthy state.
3. The authentic medicinal materials are scientifically combined.
The curative effect of the medicinal materials is ensured to the greatest extent by the genuine medicinal materials. The compatibility of medicines is scientifically carried out according to the records of the Huangdi's Endoconcha, wherein' one hundred twenty medicines are used as monarch medicines and mainly nourish life; one hundred twenty traditional Chinese medicines are ministerial medicines and mainly nourish the body; one hundred twenty medicines are used as adjuvant medicines for mainly treating diseases; the herbs are combined [ monarch, minister, assistant and guide ]. The scientific compatibility of the medicines according to the monarch, minister, assistant and guide ensures that the sex effects of the medicines after compatibility are changed in the prescription regularly, are mutually connected and restrained, and the forces of the medicines in the prescription are balanced as a whole, thereby exerting the maximum efficacy.
4. The preparation method is simple and scientific in process.
The provided preparation method is scientific and reasonable, can fully extract the effective components of the traditional Chinese medicine, and is a refining process commonly adopted in the modern production of the traditional Chinese medicine at present.
The natural herbal composition hair-loss preventing and hair-tonic, dandruff removing and itching relieving plant shampoo is prepared by compounding various natural herbal compositions, and the obtained product has good safety and can effectively prevent hair loss and hair-tonic, dandruff removing and itching relieving.
The plant shampoo is prepared by compounding the raw materials with the plant extract, and the prepared product is safe and mild and has multiple effects of preventing hair loss, strengthening hair, relieving itching, removing dandruff and the like.
Drawings
FIG. 1 is a process flow diagram of the extraction of a plant combination extract.
Detailed Description
Other advantages and effects of the present invention will become apparent to those skilled in the art from the following disclosure, which describes the embodiments of the present invention with reference to specific examples. The invention may be practiced or carried out in other embodiments that depart from the specific details, and the details of the present description may be modified or varied from the spirit and scope of the present invention.
Before the embodiments of the invention are explained in further detail, it is to be understood that the invention is not limited in its scope to the particular embodiments described below; it is also to be understood that the terminology used in the examples of the invention is for the purpose of describing particular embodiments only, and is not intended to limit the scope of the invention.
Where numerical ranges are provided in the examples, it is understood that unless otherwise stated herein, both endpoints of each numerical range and any number between the two endpoints are significant both in the numerical range. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
It should be noted that the raw materials used in the present invention are all common commercial products, and therefore the sources thereof are not particularly limited.
Example 1
An anti-hair loss, hair tonic, anti-dandruff, antipruritic plant shampoo comprising: 47.6% of water, 30% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamidide DEA, 3% of lauryl sulfate sodium, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon.
Wherein, the plant composition extract comprises the following raw materials in parts by weight: 20 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 10 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 10 parts of pseudo-ginseng, 10 parts of sea horse and 4 parts of cordyceps sinensis.
The preparation method of the plant shampoo comprises the following steps:
(1) Preparing plant composite extract, weighing the initial herbal materials according to a proportion, cleaning with water, adding into an extraction device, adding water according to a proportion, boiling, refluxing and extracting for 2 hours, and allowing proper extension. Cooling, filtering, and supplementing water loss for standby.
(2) Checking and closing a discharge valve of the emulsifying pot. Accurately weighing essence and water, and dispersing the essence with proper amount of water before adding the essence into an emulsifying pot. Then all the materials are added into an emulsifying pot, stirring is started, and the rotating speed is set to 15 revolutions per minute.
(3) The steam generator was turned on to raise the raw water temperature to 55 ℃.
(4) The stirring was turned off. Accurately weighing sodium C12-15 alkyl alcohol polyether sulfate, sodium laurylsulfate, plant combination extract, sodium chloride and polyquaternium-10, and adding into emulsifying pot.
(5) Closing the opening of the locking emulsifying tank, starting stirring, and setting the stirring rotating speed to 15 revolutions per minute.
(6) The steam generator was turned on and turned off when the temperature of the material was raised to 85 ℃, at which time preheating increased the material temperature and maintained at 85-95 ℃, maintaining the temperature in this interval, maintaining stirring for 1 hour, and allowing proper extension.
(7) And closing the steam inlet and outlet valve and opening the cooling water inlet and outlet valve.
(8) Cooling to 50 ℃, and closing the cooling water inlet and outlet valve.
(9) The stirring was turned off and cocamidopropyl betaine, sodium PCA, cocamidopropyl PG-dimethyl ammonium chloride phosphate, piroctone olamine, citric acid, disodium EDTA, and pinocembron were weighed into an emulsifying pot.
(10) Closing the opening of the locking emulsifying tank, starting stirring, and setting the stirring rotating speed to 15 revolutions per minute. The homogenization is started, and the rotating speed is set to 1300 revolutions per minute.
(11) The homogenization time was 1 hour, and the stirring time was 1 hour. Allowing for proper extension.
(12) And (5) closing homogenizing and stirring, filtering, discharging and weighing.
(13) Standing for 12 hours, and filling.
Wherein, the preparation method of the plant composition extract comprises the following steps:
s1: pulverizing Polygoni Multiflori radix, rhizoma Ligustici Chuanxiong, semen Sesami Niger, radix Angelicae sinensis, ginseng radix, caulis Spatholobi, folium Platycladi, fructus Gleditsiae Abnormalis, cistanchis herba, glycyrrhrizae radix, zingiberis rhizoma, fructus Vitics Simplicifoliae, mori fructus, aloe gel, ecliptae herba, herba Portulacae, cortex Magnolia officinalis, folium Mori, herba Speranskiae Tuberculatae, herba Taraxaci, cordyceps militaris, hirudo, notoginseng radix, hippocampus, cordyceps into 120 mesh.
S2: adding water into the plant composition according to the mass ratio of 1:10, and decocting at 100 ℃ for 2 hours (timing after boiling) to obtain an extract 1 of the plant composition;
s3: adding water according to the mass ratio of 1:8, and decocting at 100deg.C for 2 hr (after boiling) to obtain extract 2 of plant composition;
s4: mixing (extract 1, extract 2, and) the secondary extract. The liquid was concentrated to a relative density of 1.16.
S5: mixing 50% ethanol with the concentrated solution at normal temperature (note: while mixing, gently pouring ethanol, and slowly stirring, adding ethanol, and measuring with a meter to obtain 50% ethanol-containing plant composition liquid with 50% ethanol content. Precipitating the obtained plant composition solution containing 50% ethanol for 24 hr (ethanol precipitation method is to remove impurities in the extract), and filtering to obtain supernatant.
S6: finally, ethanol is separated by a steam method, and the plant combination supernatant without ethanol is obtained. The process flow chart of the extraction of the plant combination extract in the invention is shown in figure 1 in detail.
Example 2
An anti-hair loss, hair tonic, anti-dandruff, antipruritic plant shampoo comprising: 57.6% of water, 20% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamidide DEA, 3% of sodium lauryl sulfate, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon.
Wherein, the plant composition extract comprises the following raw materials in parts by weight: 15 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 10 parts of ginseng, 10 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust fruit, 10 parts of cistanche, 20 parts of liquorice, 10 parts of dried ginger, 10 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 10 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 7 parts of pseudo-ginseng, 8 parts of sea horse, and 3 parts of cordyceps sinensis.
The finished product was obtained according to the preparation method of example 1.
Example 3
An anti-hair loss, hair tonic, anti-dandruff, antipruritic plant shampoo comprising: 62.6% of water, 15% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamidide DEA, 3% of lauryl sulfate, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon.
Wherein, the plant composition extract comprises the following raw materials in parts by weight: 20 parts of fleece-flower root, 15 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 15 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 15 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 10 parts of magnolia officinalis, 15 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 8 parts of leech, 10 parts of pseudo-ginseng, 8 parts of sea horse and 2 parts of cordyceps sinensis.
The finished product was obtained according to the preparation method of example 1.
Comparative example 1
The difference from example 1 is only that the Chinese angelica, ginseng, spatholobus stem and biota orientalis leaf in the raw materials of the plant combination extract are replaced with the same amount of fructus psoraleae, radix angelicae, rehmannia glutinosa and natural indigo respectively. Namely: an anti-hair loss, hair tonic, anti-dandruff, antipruritic plant shampoo comprising: 47% of water, 30% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamide DEA, 3% of sodium lauryl sulfate, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon. Wherein, the plant composition extract comprises the following raw materials in parts by weight: 20 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of malaytea scurfpea fruit, 15 parts of dahurian angelica root, 15 parts of prepared rhizome of rehmannia, 20 parts of natural indigo, 10 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 10 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 10 parts of pseudo-ginseng, 10 parts of sea horse and 4 parts of cordyceps sinensis.
The preparation was the same as in example 1, except that the respective raw materials were replaced accordingly.
Comparative example 2
The only difference from example 1 is that the weight ratio of fructus Vitics Simplicifoliae, mori fructus, ecliptae herba and herba Taraxaci in the plant composition is 3:25:5:23.
Namely: an anti-hair loss, hair tonic, anti-dandruff, antipruritic plant shampoo comprising: 47% of water, 30% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamide DEA, 3% of sodium lauryl sulfate, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon. Wherein, the plant composition extract comprises the following raw materials in parts by weight: 20 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust spine, 10 parts of cistanche, 20 parts of liquorice, 10 parts of dried ginger, 3.75 parts of fructus viticis, 31.25 parts of mulberry, 10 parts of aloe vera gel, 6.25 parts of eclipta alba, 15 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 28.75 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 10 parts of pseudo-ginseng, 10 parts of hippocampus and 4 parts of cordyceps sinensis. The preparation was carried out as in example 1, except that the content of the individual raw materials was changed accordingly.
1. Animal test
The test method comprises the following steps: SD rats were given a male and female half, and were fed adaptively for 7d, and the rats were randomly divided into a normal control group, a model control group, and each example group of 8 rats each. Dehairing is carried out in the back area of each rat, dehairing area is 9cm multiplied by 7cm, testosterone propionate is subcutaneously injected into the rats in each group except for a normal control group (dosage is 5mg/kg, dosage frequency is 1 time/d, dosage is 60 days continuously, dosage is halved at 31 d), normal control group rats are injected with an equal amount of physiological saline, administration is carried out in a molding process, shampoo of each example is administered to each example group rat in dehairing area once daily, total dosage is 60 days, dosage is 2mL, and normal control group and model control group are administered with an equal amount of physiological saline in the same manner. After the last administration, rats were fasted, blood was taken from arteries, testosterone (T) and estradiol (E2) contents in serum were detected by ELISA, blood was taken from abdominal cavity, skin at the back hair loss part of rats was excised, homogenized and centrifuged using PBS, supernatant was taken, and Hepatocyte Growth Factor (HGF) content was detected by ELISA, and the results were counted in table 1.
TABLE 1
Examples T(ng/mL) E2(pg/mL) HGF(ng/mL)
Normal control group 6.24±1.22 187.73±22.31 1.236±0.113
Model control group 13.26±0.93 aa 162.60±15.58 a 0.894±0.098 aa
Example 1 6.98±1.32 bb 185.36±30.29 b 1.229±0.064 bb
Example 2 7.05±2.21 bb 183.29±21.63 b 1.218±0.132 bb
Example 3 7.14±1.30 bb 181.43±19.06 b 1.175±0.211 bb
Comparative example 1 9.06±2.56 bb 165.26±30.23 0.953±0.169 bb
Comparative example 2 7.87±2.89 bb 175.48±22.67 1.126±0.208 b
Note that: a is less than 0.05 compared with the normal control group, aa is less than 0.01 compared with the model control group, b is less than 0.05 compared with the model control group, and bb is less than 0.01 compared with the model control group.
There is a significant link between seborrheic alopecia and in vivo sex hormones and cell growth factors in hair follicles, so that the levels of testosterone (T) and estradiol (E2) and cell growth factors (HGF) in rats were tested, and as a result, it was found that shampoos of examples 1-3 of the present invention were effective in lowering serum testosterone levels while increasing estradiol and hepatocyte growth factor levels. In contrast, the shampoo corresponding to comparative example 1 had no significant effect on estradiol compared to the model control group, and the shampoo corresponding to comparative example 2 had no significant effect on estradiol compared to the model control group, had no significant effect on HGF.
2. Clinical trial:
the inventor randomly selects 300 baldness people with ages between 18 and 60 years old, and the male and female are not limited; 300 people with thin and soft hair, and the male and female are not limited; 300 people with scalp itch are not limited by men and women; 300 people with dandruff, and is not limited to men and women. Randomly dividing 300 test subjects into 3 groups, and respectively marking the groups as test group 1, test group 2 and test group 3; wherein, test groups 1 to 3 respectively use the plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching prepared in the embodiment 1 to 3 of the invention, the use period of the test group 3 is 3 months, the use frequency is twice a week, and the test results are shown in the following table:
table 2 (300 persons suffering from alopecia, rate of alopecia)
Experimental group Number of experimenters Number of people with obvious effect The effective number of people Invalid number of people The total effective rate is%
1 100 52 46 2 98
2 100 37 50 13 87
3 100 25 52 23 77
Note that:
the effect is shown: the number of the hair loss in the finger comb test is reduced by more than 90 percent compared with that before the use;
the method is effective: the number of the hair loss in the finger comb test is reduced by 30 to 60 percent compared with that before the use;
invalidation: the number of hair loss in the finger comb test is reduced by less than 30% compared with that before use.
Table 3 (300 persons with thin and soft hair, hair tonic)
Experimental group Number of experimenters Number of people with obvious effect The effective number of people Invalid number of people The total effective rate is%
1 100 31 57 12 88
2 100 28 44 28 72
3 100 11 56 33 67
Human hair, even if grown on the same scalp, is different in thickness. The thickness of hair varies with the growing environment, age, sex, health condition, etc., and is different from person to person. The thickness of the hair is determined by the size of the hair diameter. Generally, they can be classified into coarse hair, general hair, and fine hair. The diameter of the thick hair is 90 microns after the thick hair is tested by an instrument; typically the hair has a diameter of between 60 and 90 microns; the diameter of the fine hair is below 60 microns.
Note that:
the effect is shown: the diameter of the thick hair is 90 microns after the thick hair is tested by an instrument;
the method is effective: typical hair diameters between 60 and 90 microns can be seen after instrumental testing;
invalidation: after being tested by an instrument, the diameter of the fine hair can be seen to be below 60 microns;
table 4 (300 scurf removing rate)
Experimental group Number of experimenters Number of people with obvious effect The effective number of people Invalid number of people The total effective rate is%
1 100 66 29 5 95
2 100 48 38 14 86
3 100 28 49 23 77
In the test, the scalp is generally scored in a plurality of areas, or the most severe dandruff area is scored, and the score is above a certain limiting value as a standard for inclusion in the subject. The degree of dandruff is clinically classified as grade 4: 0 = no scale; 1 = mild scale; 2 = medium scale; 3 = severe scale; 4 = extremely severe scale.
Two days before the experiment, two special doctors are fixed to check, the most severe dandruff parts are selected on the left side and the right side, the number of the skin fragments in the scalp area is scored according to the size of each 1 square centimeter, and 0 = no dandruff; l = light, less than 5 pieces of dandruff per square centimeter of scalp; 2=moderate, 5-10 pieces of scalp dander per flat instant rice; 3 = severe, 10-20 pieces of dandruff per square centimeter of scalp. 4 = extremely severe, more than 20 pieces per square centimeter of scalp dander. And 3 observation areas are selected from each side symmetrically, the scoring values of each dandruff are added, and the average value is taken for statistical analysis. Subject inclusion criteria: dandruff scores were at or above moderate.
Note that:
the effect is shown: observing with a microscopic examination instrument, wherein the number of the skin chips in each scalp area is 0-5 per 1 square centimeter;
the method is effective: observing with a microscopic examination instrument, wherein the number of the skin chips in each scalp area is 5-10 per 1 square centimeter;
invalidation: observing with a microscopic examination instrument, wherein the number of the skin chips in each scalp area with the size of 1 square centimeter is more than 20;
table 5 (300 scalp itch person, antibacterial rate)
Figure SMS_1
The scalp itch is mainly caused by the following aspects: 1. hair comparison oil is also a phenomenon that causes itching of the scalp, and this is mainly due to seborrheic dermatitis caused by pores clogged with sebum secreted by sebaceous glands of the scalp. 2. Scalp itching caused by dandruff on the scalp surface is mainly caused by fungal infection. 3. Mainly, the phenomena of night stay, fatigue, body resistance decline and irregular diet can also cause scalp secretion increase, and the phenomena of itching caused by inflammation induced on the surface of the scalp are stimulated.
The effectiveness of the antifungal agents was evaluated quantitatively. The effectiveness is evaluated mainly by a method of quantifying the colony number of malassezia after sampling and culturing.
Sampling and culturing a subject specimen:
the scalp of each subject is divided into left and right sides, and three square regions (with the area of 4 cm) with the diameter of 2cm are symmetrically taken at the junction of connecting lines of 5cm, 12cm and 19cm respectively from the normal central line 2em of the scalp and the forehead hairline 2 ) Taking materials by using a sterilized disposable microporous breathable adhesive tape or sterile cotton swab. Dipping a proper amount of physiological saline by using a sterile cotton swab, repeatedly scrubbing the scalp for three times in each area, putting the scrubbed dandruff cotton swab into a lml physiological saline disinfection centrifuge tube for nine times, uniformly shaking, inoculating to a chloramphenicol Sha Baoshi glucose agar culture dish (diameter of 9 cm) containing 5% sesame oil, culturing for 7-10 days at a constant temperature of 37 ℃, observing colony morphology of all grown colonies every other day, and picking a single colony grown on a culture medium for a color-dyeing mirror to determine whether the colony is malassezia. When the laboratory is used for observing and dyeing, a small amount of strain is picked up and is respectively dripped on a glass slide, the gram of ink dye liquor is prepared for dyeing, and the dyeing time and the dyeing effect (positive rate method) are observed and recorded under a microscope. The number of malassezia colonies per square centimeter of scalp (colony count method) was counted on the eighth day. The standard is adopted: selecting 5 fields of view under high power mirror, and dividing each high power field of view into 0 min<5 spores, negative; 1 min = fewer, (10±3) "+";2 minutes = medium, (20±5) "++";3 min-4 min = plentiful or dense more than or equal to (40+/-10) "++".
Note that:
the effect is shown: observing with a microscopic instrument, wherein the number of malassezia colonies per square centimeter scalp is less than 5 spores;
the method is effective: observing with a microscopic instrument, wherein the number of the malassezia colonies per square centimeter scalp is small (10+/-3) and "+";
invalidation: observing with a microscopic instrument, wherein the colony number of the malassezia is more than or equal to (40+/-10) per square centimeter scalp, + ++ ";
finally, it should be noted that the above description is only for illustrating the technical solution of the present invention, and not for limiting the scope of the present invention, and that the simple modification and equivalent substitution of the technical solution of the present invention can be made by those skilled in the art without departing from the spirit and scope of the technical solution of the present invention.

Claims (7)

1. A plant shampoo for preventing hair loss, strengthening hair, removing dandruff and relieving itching is characterized in that: comprises the following components in percentage by weight: 30-60% of water, 8-50% of plant combined extract, 5-15% of C12-15 alkanol polyether sodium sulfate, 2-5% of cocamidopropyl betaine, 2-6% of lauryl sulfate sodium, 1-5% of cocamidopropyl betaine, 0.1-2% of sodium chloride, 0.5-3% of PCA sodium, 0.1-1% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.01-0.5% of piroctone olamine, 0.01-0.5% of essence, 0.1-0.5% of polyquaternium, 0.01-0.3% of citric acid, 0.01-0.1% of EDTA disodium and 0.01-0.08% of kapinone;
the plant composition extract comprises the following raw materials in parts by weight: 10-20 parts of polygonum multiflorum, 5-15 parts of ligusticum wallichii, 5-15 parts of black sesame, 10-20 parts of angelica sinensis, 5-15 parts of ginseng, 10-20 parts of caulis spatholobi, 15-35 parts of cacumen biotae, 10-20 parts of fructus gleditsiae, 5-15 parts of cistanche, 10-30 parts of liquorice, 5-15 parts of dried ginger, 5-15 parts of fructus viticis, 10-20 parts of mulberry, 5-15 parts of aloe vera gel, 10-20 parts of eclipta alba, 10-20 parts of purslane, 10-20 parts of magnolia officinalis, 10-20 parts of mulberry leaf, 15-25 parts of garden balsam stem, 10-20 parts of dandelion, 5-10 parts of cordyceps militaris, 5-10 parts of leech, 5-10 parts of pseudo-ginseng, 5-15 parts of cordyceps sinensis and 2-5 parts of cordyceps sinensis.
2. The plant shampoo of claim 1, wherein: comprises the following components in percentage by weight: 47.6% of water, 30% of plant combination extract, 11% of C12-15 alkyl polyether sodium sulfate, 3% of cocamidide DEA, 3% of lauryl sulfate sodium, 2% of cocamidopropyl betaine, 1% of sodium chloride, 1% of PCA sodium, 0.5% of cocamidopropyl PG-dimethyl ammonium chloride phosphate, 0.25% of piroctone olamine, 0.25% of essence, 0.2% of polyquaternium-10.2%, 0.1% of citric acid, 0.05% of EDTA disodium and 0.05% of pinon.
3. The plant shampoo of claim 1, wherein: the plant composition extract comprises the following raw materials in percentage by weight: 20 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 10 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 10 parts of pseudo-ginseng, 10 parts of sea horse and 4 parts of cordyceps sinensis.
4. The plant shampoo of claim 1, wherein: the plant composition extract comprises the following raw materials in percentage by weight: 15 parts of fleece-flower root, 10 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 10 parts of ginseng, 10 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 10 parts of Chinese honeylocust fruit, 10 parts of cistanche, 20 parts of liquorice, 10 parts of dried ginger, 10 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 10 parts of purslane, 15 parts of magnolia officinalis, 20 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 10 parts of leech, 7 parts of pseudo-ginseng, 8 parts of sea horse, and 3 parts of cordyceps sinensis.
5. The plant shampoo of claim 1, wherein: the plant composition extract comprises the following raw materials in percentage by weight: 20 parts of fleece-flower root, 15 parts of szechuan lovage rhizome, 10 parts of black sesame, 10 parts of Chinese angelica, 15 parts of ginseng, 15 parts of suberect spatholobus stem, 20 parts of cacumen biotae, 15 parts of Chinese honeylocust fruit, 10 parts of desertliving cistanche, 20 parts of liquorice, 15 parts of dried ginger, 15 parts of fructus viticis, 20 parts of mulberry, 10 parts of aloe vera gel, 20 parts of eclipta alba, 15 parts of purslane, 10 parts of magnolia officinalis, 15 parts of mulberry leaf, 20 parts of garden balsam stem, 15 parts of dandelion, 10 parts of cordyceps militaris, 8 parts of leech, 10 parts of pseudo-ginseng, 8 parts of sea horse and 2 parts of cordyceps sinensis.
6. A method of preparing a plant shampoo according to any one of claims 1 to 5, characterized in that: the method comprises the following steps:
(1) Preparing plant composition extract for later use;
(2) Dispersing essence with water, stirring, and heating;
(3) Continuously adding C12-15 sodium alkyl alcohol polyether sulfate, sodium lauryl sulfate, plant combination extract, sodium chloride and polyquaternium-10, stirring, continuously heating, and stirring;
(4) Cooling, adding cocamide DEA, cocamidopropyl betaine, sodium PCA, cocamidopropyl PG-dimethyl ammonium chloride phosphate, piroctone olamine, citric acid, EDTA disodium, and pinocembron, stirring, homogenizing, and filtering.
7. The method of manufacturing according to claim 6, wherein: the preparation method of the plant composition extract comprises the following steps:
s1: pulverizing the plant composition, adding water, decocting, mixing the extractive solutions, and concentrating to obtain concentrated solution;
s2: mixing the concentrated solution with ethanol to obtain a plant combination solution;
s3: precipitating the plant combination liquid with ethanol, and filtering to obtain supernatant;
s4: separating ethanol in the supernatant to obtain plant composition extract.
CN202210798060.7A 2022-07-06 2022-07-06 Plant shampoo capable of preventing hair loss, strengthening hair, removing dandruff and relieving itching and preparation method thereof Active CN115006336B (en)

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