CN111759919A - Freckle-removing traditional Chinese medicine composition and preparation method thereof, freckle-removing traditional Chinese medicine face cream and preparation method thereof - Google Patents
Freckle-removing traditional Chinese medicine composition and preparation method thereof, freckle-removing traditional Chinese medicine face cream and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention relates to the technical field of traditional Chinese medicine skin care, in particular to a freckle-removing traditional Chinese medicine composition, a preparation method of the freckle-removing traditional Chinese medicine composition, a traditional Chinese medicine skin care preparation containing the freckle-removing traditional Chinese medicine composition, freckle-removing face cream and a preparation method of the face cream. The freckle-removing traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile. The traditional Chinese medicine composition is prepared, extracted and added into cosmetics, and can repair skin damage, such as: sunburn, acne marks, slight speckle fading, skin-friendly feeling of the cosmetic and smoothness of the cosmetic.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine skin care, in particular to a freckle-removing traditional Chinese medicine composition, a preparation method of the freckle-removing traditional Chinese medicine composition, a traditional Chinese medicine skin care preparation containing the freckle-removing traditional Chinese medicine composition, freckle-removing face cream and a preparation method of the face cream.
Background
Plaques are brown spots on the face that are formed as a result of an increase in skin melanin. The spots worsen after exposure to sunlight. Women with menstrual disorders or pregnancy also develop spots. Plaques are diseases which are localized in color change but which belong to the skin class without elevations and depressions. The spots are formed along with age stress, bad living habits and the oxidation of healthy skin cells, the loss of the activity of the cells and the accumulation on the surface of the skin due to the failure of normal metabolism. The common spots include freckle, chloasma, senile plaque, dermal spot, plumbum and mercuric spot, hormone spot, and color-deposited spot. The most common of the young and middle-aged women are chloasma, sunburn and acne marks, which are all caused by acquired factors.
Chloasma is mostly seen in young and middle-aged women, skin lesions are light brown to dark brown patches which are generally symmetrical and in patch shapes, can also be seen in forehead, eyebrow, cheeks, nose, periphery of mouth and the like, have clear boundaries and no subjective symptoms, and the skin lesions are deepened after the sun exposure, and some women suffer from deepened color before menstruation.
Sunburn, as the name suggests, is caused by sun exposure, and therefore occurs well in both sexes of middle-aged people, 40 and 50 years old, but also in early years of 20 and 30 years old. Clinically, sunburn is a brownish black spot focus which is clearly defined in the country and can be from sesame to coin. The good hair parts are the face, the back of the hand, the back, the chest, the upper limbs and the lower limbs, but the focus of the face is larger and more obvious.
Due to excessive secretion of sebaceous glands in the dermis layer of the skin, endocrine disturbance and the like, part of beauty nurses can generate acne on the face in the adolescence stage, the acne belongs to local inflammatory reaction of the skin, and pigmentation, also called acne marks, can be formed on the surface of the skin in the healing process of the acne.
Most Asian women pay high attention to freckle removal, and the traditional Chinese medicine is applied to cosmetics, can protect skin and achieve the effect of skin treatment due to natural non-side effects, and is more and more popular with people who remove freckles.
Patent CN108096147A discloses a preparation method of a traditional Chinese medicine mask for removing freckles, whitening skin, maintaining beauty and keeping young, the traditional Chinese medicines of the preparation method of the traditional Chinese medicine mask comprise: radix pseudostellariae, rhizoma cyperi, scorpion, stiff silkworm, poria cocos, radix angelicae, radix paeoniae rubra, angelica sinensis, cynanchum atratum, beautyberry, ligusticum wallichii, motherwort, szechwan chinaberry fruit, artemisia anomala, ginger juice, radix paeoniae alba, Chinese yam, bighead atractylodes rhizome, astragalus mongholicus, rhizoma typhonii, polygonatum odoratum, almond, ampelopsis japonica, semen coicis, cuttlebone, codonopsis pilosula, angelica sinensis, gypsum, bletilla striata, pearl powder, gardenia, coptis chinensis, radix rehmanniae, salvia miltiorrhiza, scutellaria baicalensis, loofah sponge, stiff silkworm, talc, rhizoma kaempferiae, clove, liquorice, oyster, tribulus terrestris, garden balsam stem, safflower carthamus, borneol, polygonum multiflorum, radix asparagi, ophiopogon root, cortex moutan, ginseng, propolis, deer oil, deer fetus, egg oil, human placenta, dried orange peel, wolfberry, pseudo-ginseng, semen cuscutae, fructus psoraleae, rhizoma nardostachyos, polygala, caulis spatholobi, herba Houttuyniae, herba Saussureae Involueratae, Cordyceps, Ganoderma, herba asari, flos Caryophylli, spina Gleditsiae, herba Patriniae, fructus forsythiae, rhizoma Smilacis Glabrae, and rhizoma paridis. The preparation method of the traditional Chinese medicine mask comprises the following steps: grinding the traditional Chinese medicines into fine powder of 80-120 meshes, adding starch and vegetable oil, mixing and sieving to obtain traditional Chinese medicine powder; b. mixing yeast and clear water, standing for 10-30 minutes, pouring into the traditional Chinese medicine powder in the step a, and stirring into thick paste; c. b, putting the paste obtained in the step b at the temperature of 20-40 ℃ for fermentation to 2-3 times of the size of the paste to obtain fermented paste; d. c, adding water into the paste fermented in the step c to adjust the paste to be slightly thicker than the soybean milk, and fermenting for 2 times to obtain 2 times of fermented thin paste; e. and (3) applying oil on the surface of the special die, putting the special die on a furnace for heating, adding the thin paste obtained after 2 times of fermentation, pressing the thin paste obtained after 2 times of fermentation into thin wafers, and taking out the wafers to obtain the traditional Chinese medicine mask. The traditional Chinese medicine mask has a plurality of medicinal tastes, is provided with both animal medicines and plant medicines, contains medicinal materials such as deer oil, deer placenta, human placenta which are not purchased well, and also contains famous and precious medicinal materials such as ginseng, snow lotus herb, cordyceps sinensis and the like, firstly, the medicinal materials in the prescription are not easy to be packed, secondly, the cost is high, the preparation and the use need to be fermented again, and the animal medicines are not easy to be stored after being fermented. The components of the traditional Chinese medicine mask for removing freckles, whitening, beautifying and nourishing the face comprise toxic medicines such as scorpion, stiff silkworm (white stiff silkworm), szechwan chinaberry fruit and asarum, and also some medicines forbidden to be used in skin care products and cosmetics such as angelica dahurica (experimental research easily causes photosensitive reaction), and uncertain factors have potential risks of causing skin problems.
Patent CN105853319A discloses a purslane facial cream for diminishing inflammation, resisting allergy and removing freckles, which comprises the following raw material medicines in parts by weight: 10-50 parts of purslane, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of astragalus membranaceus, 10-20 parts of motherwort, 10-20 parts of centella, 10-20 parts of salvia miltiorrhiza, 10-20 parts of selfheal, 10-20 parts of trichosanthes root, 10-20 parts of safflower, 10-20 parts of radix paeoniae alba, 10-20 parts of bletilla striata, 10-20 parts of mint, 10-20 parts of lithospermum, 10-20 parts of radix ampelopsis, 10-20 parts of radix angelicae, 10-20 parts of geranium, 10-20 parts of calendula, 10-20 parts of angelica sinensis, 10-20 parts of white muscardine silkworm, 10-20 parts of rose and 10-20 parts of stringy stonecrop. The face cream contains 21 traditional Chinese medicines, is complex in formula, contains toxic medicine of stiff silkworm (white stiff silkworm) and banned medicine of angelica dahurica (experimental research easily causes photosensitive reaction), and has potential risk of causing skin problems due to uncertain factors.
Therefore, the research and development of natural freckle-removing products with good safety, obvious freckle-inhibiting effect, good cost performance and convenient preparation and use still belongs to one of the main research directions of the current traditional Chinese medicine cosmetic industry.
Disclosure of Invention
In order to solve the technical problems, the invention provides a freckle-removing traditional Chinese medicine composition, a preparation method of the freckle-removing traditional Chinese medicine composition, a traditional Chinese medicine skin care preparation containing the freckle-removing traditional Chinese medicine composition, freckle-removing face cream and a preparation method of the face cream.
The invention is realized by the following technical scheme:
a freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile.
Preferably, the freckle-removing traditional Chinese medicine composition is prepared from the following raw materials in parts by weight:
5 parts of lithospermum; 5 parts of angelica; 2.5 parts of Pu' er tea; 2.5 parts of rose; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile.
In the freckle-removing traditional Chinese medicine composition, the arnebia euchroma is preferably arnebia euchroma, and the arnebia euchroma has better effect due to the special climate of Xinjiang. The angelica is preferably selected from the head of the angelica, the angelica is divided into the head part, the body part and the tail part, the angelica is biased to enrich the blood and promote the blood circulation, the body part enriches the blood, the tail part breaks the blood and the freckle is mainly used for removing the freckle on the face, and the angelica is selected to enhance the efficacy of the head and the face. When the freckle-removing traditional Chinese medicine composition is extracted, the head of the angelica is cut into slices of 1-10mm, so that the effective ingredients are conveniently dissolved out. The rose is preferably Damascus rose buds which belong to the top-grade roses, so that the quality is better and the effect is stronger. Radix Paeoniae alba and rhizoma Ligustici are the traditional Chinese medicines specified in Chinese pharmacopoeia. Chamomile is a common cosmetic raw material. The Pu her tea is selected from Yunnan Qizi cake Pu her.
The preparation method of the freckle-removing traditional Chinese medicine composition comprises the following steps:
(1) taking 100 parts of caprylic-capric glyceride and 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in caprylic/capric glyceride, stirring for 3 min every 4 hr, soaking for 120 hr, heating the mixed solution to 50 deg.C, maintaining for 3 min, and filtering to obtain the final product.
The stirring speed is 50-60 r/min.
A freckle-removing traditional Chinese medicine preparation comprises the freckle-removing traditional Chinese medicine extract prepared by the preparation method of the freckle-removing traditional Chinese medicine composition, and auxiliary materials required by preparation of a pharmaceutical preparation or a cosmetic preparation. The freckle-removing traditional Chinese medicine preparation is preferably a cosmetic or skin care preparation, such as cream, essence, facial mask and a product for cleaning skin.
The freckle-removing face cream is characterized by comprising the traditional Chinese medicine oil prepared by the preparation method of the freckle-removing traditional Chinese medicine composition and auxiliary materials required by face cream preparation.
The freckle-removing face cream is prepared from the following raw materials in percentage by weight:
in the freckle-removing facial cream, the F-1000 is biological carbohydrate gum-1; the HAP is p-hydroxyacetophenone; the EMT10 is a hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer; 1449 is isononyl isononanoate; the DC345 is a mixture of cyclopentadidimethyl siloxane and cyclohexasiloxane, and the weight ratio of the cyclopentadidimethyl siloxane to the cyclohexasiloxane is 4: 1; the DM100 is polydimethylsiloxane; the M-68 is a mixture of cetearyl alcohol and cetearyl glucoside, and the weight ratio of the cetearyl alcohol to the cetearyl glucoside is 3: 1; the BHT is butylated hydroxytoluene; the 16-18 alcohol is cetearyl alcohol; the 1, 2-hexanediol.
The preparation method of the freckle-removing face cream comprises the following steps:
(1) adding water, F-1000, betaine, glycerol, HAP and EMT-10 into an emulsifying pot, stirring, heating to 90 ℃, and sterilizing at constant temperature for 15 minutes;
(2) adding the prepared freckle-removing traditional Chinese medicine extract, olive oil, phytosterol ester, enkol, DC345, DM100, M-68, VE, BHT and 16-18 alcohol into an oil pan, and heating to 85 ℃;
(3) adding the mixture in the oil pan into an emulsifying pan, stirring and emulsifying;
(4) after emulsification is finished, cooling, adding KMO-6, water-locking magnet and rose essential oil when the temperature is reduced to 45 ℃, uniformly stirring, and taking out of the pot to obtain the final product.
The effects of the components in the face cream are as follows:
the invention has the beneficial effects that:
(1) the prescription of the freckle-removing traditional Chinese medicine composition takes the alkanna tinctoria root as a monarch, and the alkanna tinctoria root is cool and hot in blood and can promote blood generation, and has the effects of relieving fever, diminishing inflammation, enriching blood and sterilizing. The angelica is taken as the minister, and the angelica has the functions of nourishing blood, invigorating blood circulation and moistening skin, has obvious cleaning, pus discharge and repairing functions when being used together with the alkanna tinctoria root, and promotes the formation of granulation. The rose flower has the effects of promoting qi circulation, relieving depression, harmonizing blood and relieving pain, is commonly used for calming the liver, nourishing the stomach and promoting blood circulation by ancient people, is researched by modern times, has the functions of moistening skin, promoting cell regeneration and fading fine wrinkles by external application, has pleasant fragrance, and is an assistant in the formula. White peony root, Chinese ligusticum rhizome, chamomile and Pu' er tea have synergistic effect, and can nourish blood, whiten skin, detoxify, diminish inflammation, promote aging and make skin glow.
(2) The freckle-removing traditional Chinese medicine composition is prepared by adding rose flowers on the basis of basic formulas of lithospermum and angelica sinensis in Mingdingcheng Chenkuang, and then adding white paeony root, ligusticum, chamomile and Pu' er, has simple medicinal taste, is researched and practiced in a large number of aspects of effectiveness, safety, color and smell, and is a product which can be safely used for a long time and has the effects of whitening, detoxifying, diminishing inflammation, removing freckles and promoting skin tissue regeneration.
(3) The traditional Chinese medicine oil soaked in the traditional Chinese medicine according to the proportion is added into cosmetics, and can repair skin damage, such as: sunburn, acne marks, slight speckle fading, skin-friendly feeling of the cosmetic and smoothness of the cosmetic.
(4) In the prior art, most of the traditional Chinese medicines are extracted from single Chinese medicines, and the mixed extraction in the proportion has the advantage that the drug effects of the traditional Chinese medicines are related through the proportion, so that the drug effects are more obvious.
Detailed Description
The present invention will be further described with reference to specific examples so that those skilled in the art may better understand the present invention, but the present invention is not limited thereto.
In the embodiment of the invention, the F-1000 is purchased from Xianting France company; the betaine is purchased from Shanghai New trade, Inc.; the HAP was purchased from the THOR us; the EMT-10 was purchased from Shanghai Saifu trade, Inc.; the 1449 is purchased from Shanghai New trade, Inc.; the phytosterol esters were purchased from Shanghai New trade, Inc.; the enskin ester was purchased from Shanghai New trade, Inc.; the DC345 is available from Dow Corning; the BHT was purchased from shanghai seifof trading, ltd; the 16-18 alcohol was purchased from Shanghai New trade, Inc.; the KMO-6 is purchased from Shanghai Luya Biotechnology Co., Ltd, Japan; the water-locking magnet is purchased from Shanghai Luya biotechnology limited; the rose essential oil was purchased from Sichuan rose cereals.
Example 1
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
5 parts of Sinkiang arnebia root; 5 parts of angelica sinensis head slices; 2.5 parts of Pu' er tea; 2.5 parts of Damascus rose buds; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile.
Example 2
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
1 part of Sinkiang arnebia root; 1 part of angelica sinensis head slice; 1 part of Pu' er tea; 1 part of Damascus rose buds; 1 part of white peony root; 1 part of ligusticum and 1 part of chamomile.
Example 3
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
10 parts of Sinkiang lithospermum; 10 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 5 parts of white peony root; 5 parts of ligusticum and 5 parts of chamomile.
Example 4
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
1 part of Sinkiang arnebia root; 10 parts of angelica sinensis head slices; 1 part of Pu' er tea; 5 parts of Damascus rose buds; 1 part of white peony root; 5 parts of ligusticum and 1 part of chamomile.
Example 5
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
10 parts of Sinkiang lithospermum; 1 part of angelica sinensis head slice; 5 parts of Pu' er tea; 1 part of Damascus rose buds; 5 parts of white peony root; 1 part of ligusticum and 5 parts of chamomile.
Example 6
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
8 parts of Sinkiang arnebia root; 8 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 2 parts of white peony root; 2 parts of ligusticum and 2 parts of chamomile.
Example 7
A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
5 parts of Sinkiang arnebia root; 5 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 5 parts of white peony root; 2 parts of ligusticum and 2 parts of chamomile.
Example 8
A preparation method of a freckle-removing traditional Chinese medicine composition comprises the following steps:
(1) taking 100 parts of caprylic-capric glyceride and 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in caprylic/capric glyceride, stirring for 3 min every 4 hr, soaking for 120 hr, heating to 50 deg.C, maintaining for 3 min, and filtering to obtain the final product.
Example 9
A preparation method of a freckle-removing traditional Chinese medicine composition comprises the following steps:
(1) taking 100 parts of caprylic capric glyceride and 5 parts of Sinkiang arnebia root; 5 parts of angelica sinensis head slices; 2.5 parts of Pu' er tea; 2.5 parts of Damascus rose buds; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in caprylic/capric glyceride, stirring every 4 hr for 3 min, soaking for 120 hr, heating to 50 deg.C, maintaining for 3 min, and filtering to obtain the final product.
Example 10
A preparation method of a freckle-removing traditional Chinese medicine composition comprises the following steps:
(1) taking 100 parts of caprylic-capric glyceride and 8 parts of Sinkiang arnebia root; 8 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 2 parts of white peony root; 2 parts of ligusticum and 2 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in caprylic/capric glyceride, stirring every 4 hr for 3 min, soaking for 120 hr, heating to 50 deg.C, maintaining for 3 min, and filtering to obtain the final product.
Example 11
A preparation method of a freckle-removing traditional Chinese medicine composition comprises the following steps:
(1) taking 100 parts of caprylic capric glyceride and 5 parts of Sinkiang arnebia root; 5 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 5 parts of white peony root; 2 parts of ligusticum and 2 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in caprylic/capric glyceride, stirring every 4 hr for 3 min, soaking for 120 hr, heating to 50 deg.C, maintaining for 3 min, and filtering to obtain the final product.
Example 12
The freckle-removing face cream is prepared from the following raw materials in percentage by weight:
the preparation method of the freckle-removing face cream comprises the following steps:
(1) adding water, F-1000, betaine, glycerol, HAP and EMT-10 into an emulsifying pot, stirring, heating to 90 ℃, and sterilizing at constant temperature for 15 minutes;
(2) adding the Chinese medicinal extract with speckle removing effect, 1449, oleum Olivarum, phytosterol ester, enkol, DC345, DM100, M-68, VE, BHT, and 16-18 alcohol into oil pan, and heating to 85 deg.C;
(3) adding the mixture in the oil pan into an emulsifying pan, stirring and emulsifying;
(4) after emulsification is finished, cooling, adding KMO-6, water-locking magnet and rose essential oil when the temperature is reduced to 45 ℃, uniformly stirring, and taking out of the pot to obtain the final product.
The traditional Chinese medicine freckle-removing face cream is tested, and the purpose is as follows: the formulations were tested for effectiveness.
The testing process comprises the following steps: from 3/1 in 2020, the duration is 4 weeks, and the duration is up to 3/28 in 2020, all tested persons are volunteers, teachers, clerks, general workers in workshops, bank counter workers, finance workers, community workers and the like, and the face cream used by the volunteers in the test group is the traditional Chinese medicine freckle removing face cream of the invention, and the common face cream used by the volunteers in the control group is common face cream.
First, front-end data packet: (the formula proportion of the freckle-removing traditional Chinese medicine composition in the skin care product used by the front-end data group is 5 parts of Sinkiang arnebia root, 5 parts of Chinese angelica root head slices, 2.5 parts of Pu' er tea, 2.5 parts of damascus rose buds, 2.5 parts of white paeony root, 2.5 parts of Chinese ligusticum rhizome and 2.5 parts of chamomile, and the preparation method is the same as the embodiment 12)
A first group: mild plaques, age 30-50 women 10
Second group: sunburn, age 30-50 women 10 people
Third group: acne mark, age 30-50 female 10 people
Fourth group, control group: female 10 people with slight spot or sunburn or acne mark
| Group/variation | First week | Second week | The third week | The fourth side | Remarks/conclusions |
| First group | Without change | Without change | Slightly bland in color | Become remarkably light | Obviously improve |
| Second group | Without change | Without change | Slight improvement | Obviously improve | Obviously improve |
| Third group | The change is not obvious | Become light | Become light | Become remarkably light | Obviously improve |
| Fourth group | Without change | Without change | Without change | Without change | Without change |
And (4) conclusion: after the application for 4 weeks, the test volunteers have obviously improved spots, acne marks and sunburn, and the control group has no change.
Secondly, the median data group (the prescription proportion of the freckle-removing traditional Chinese medicine composition in the skin care product used by the middle-end data group is 8 parts of Sinkiang arnebia root, 8 parts of angelica sinensis head, 5 parts of Pu' er tea, 5 parts of Damascus rose buds, 2 parts of white paeony root, 2 parts of Chinese ligusticum rhizome and 2 parts of chamomile, and the preparation method is the same as that of the example 12)
A first group: mild plaques, age 30-50 women 10
Second group: sunburn, age 30-50 women 10 people
Third group: acne mark, age 30-50 female 10 people
Fourth group, control group: slight freckle, sunburn and acne mark in 10 women
And (4) conclusion: after the test composition is continuously used for 4 weeks, the spots and sunburn of the volunteers in the test group are slightly improved, the acne marks are obviously improved, and the control group is unchanged. Thirdly, the back end data group is divided (the prescription proportion of the freckle-removing traditional Chinese medicine composition in the skin care product used by the back end data group is 5 parts of Sinkiang arnebia root, 5 parts of angelica sinensis head, 5 parts of Pu' er, 5 parts of Damascus rose bud, 5 parts of white paeony root, 2 parts of Chinese ligusticum rhizome and 2 parts of chamomile, the preparation method is the same as that of the embodiment 12)
A first group: mild plaques, age 30-50 women 10
Second group: sunburn, age 30-50 women 10 people
Third group: acne mark, age 30-50 female 10 people
Fourth group, control group: slight freckle, sunburn and acne mark in 10 women
| Group/variation | First week | Second week | The third week | The fourth side | Remarks/conclusions |
| First group | Without change | Slightly bland in color | Slightly bland in color | Become remarkably light | Obviously improve |
| Second group | Without change | Slightly bland in color | Slight improvement | Obviously improve | Obviously improve |
| Third group | The change is not obvious | Become light | Become light | Become remarkably light | Obviously improve |
| Fourth group | Without change | Without change | Without change | Without change | Without change |
And (4) conclusion: after the application for 4 weeks, the test volunteers have obviously improved spots, acne marks and sunburn, and the control group has no change.
To summarize: the freckle-removing traditional Chinese medicine composition with different proportions is continuously used for 4 weeks, the freckles, acne marks and sunburn of the volunteers in the test group are obviously improved, and the control group is unchanged. The relative dosage of Pu' er tea, rose and white paeony root relative to the lithospermum and the angelica can be increased, so that the treatment effect of sunburn can be improved.
Claims (8)
1. A freckle-removing traditional Chinese medicine composition is composed of the following raw materials in parts by weight:
1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile.
2. The freckle-removing traditional Chinese medicine composition according to claim 1 is characterized by comprising the following raw materials in parts by weight:
5 parts of lithospermum; 5 parts of angelica; 2.5 parts of Pu' er tea; 2.5 parts of rose; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile.
3. The method for preparing the freckle-removing traditional Chinese medicine composition according to claim 1 or 2, which is characterized by comprising the following steps of:
(1) taking 100 parts of caprylic-capric glyceride and 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in caprylic/capric glyceride, stirring for 3 min every 4 hr, soaking for 120 hr, heating the mixed solution to 50 deg.C, maintaining for 3 min, and filtering to obtain the final product.
4. A freckle-removing traditional Chinese medicine preparation, which is characterized by comprising the freckle-removing traditional Chinese medicine extract as claimed in claim 3, and auxiliary materials required by preparation of a pharmaceutical preparation or a cosmetic preparation.
5. A freckle-removing facial cream, which is characterized by comprising the freckle-removing traditional Chinese medicine extract as claimed in claim 3 and auxiliary materials required by facial cream preparation.
6. The spot-removing cream according to claim 5, which is prepared from the following raw materials in percentage by weight:
7. the spot-removing cream of claim 6, wherein the F-1000 is biosaccharide gum-1; the HAP is p-hydroxyacetophenone; the EMT10 is a hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer; 1449 is isononyl isononanoate; the DC345 is a mixture of cyclopentadidimethyl siloxane and cyclohexasiloxane, and the weight ratio of the cyclopentadidimethyl siloxane to the cyclohexasiloxane is 4: 1; the DM100 is polydimethylsiloxane; the M-68 is a mixture of cetearyl alcohol and cetearyl glucoside, and the weight ratio of the cetearyl alcohol to the cetearyl glucoside is 3: 1; the BHT is butylated hydroxytoluene; the 16-18 alcohol is cetearyl alcohol; the KMO-6 is 1, 2-hexanediol.
8. The method of preparing a spot-removing cream according to claim 6, comprising the steps of:
(1) adding water, F-1000, betaine, glycerol, HAP and EMT-10 into an emulsifying pot, stirring, heating to 90 ℃, and sterilizing at constant temperature for 15 minutes;
(2) adding the freckle-removing traditional Chinese medicine extract prepared according to the claim 3, olive oil, phytosterol ester, enkol, DC345, DM100, M-68, VE, BHT and 16-18 alcohol into an oil pan, and heating to 85 ℃;
(3) adding the mixture in the oil pan into an emulsifying pan, stirring and emulsifying;
(4) after emulsification is finished, cooling, adding KMO-6, water-locking magnet and rose essential oil when the temperature is reduced to 45 ℃, uniformly stirring, and taking out of the pot to obtain the final product.
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| CN112807404A (en) * | 2021-02-22 | 2021-05-18 | 黄乐真 | Traditional Chinese medicine extract formula for removing freckles and preparation method thereof |
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