CN111658558A - Traditional Chinese medicine freckle-removing essence and preparation method thereof - Google Patents

Traditional Chinese medicine freckle-removing essence and preparation method thereof Download PDF

Info

Publication number
CN111658558A
CN111658558A CN202010617150.2A CN202010617150A CN111658558A CN 111658558 A CN111658558 A CN 111658558A CN 202010617150 A CN202010617150 A CN 202010617150A CN 111658558 A CN111658558 A CN 111658558A
Authority
CN
China
Prior art keywords
parts
traditional chinese
chinese medicine
freckle
essence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010617150.2A
Other languages
Chinese (zh)
Inventor
王建华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Zero Hour Trading Co ltd
Original Assignee
Nanjing Zero Hour Trading Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Zero Hour Trading Co ltd filed Critical Nanjing Zero Hour Trading Co ltd
Priority to CN202010617150.2A priority Critical patent/CN111658558A/en
Publication of CN111658558A publication Critical patent/CN111658558A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/004Aftersun preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to the technical field of skin care, and particularly relates to a traditional Chinese medicine freckle-removing essence and a preparation method thereof. The traditional Chinese medicine freckle-removing essence is prepared from water, AVC, betaine, allantoin, transparent xanthan gum, glycerol, small molecular hyaluronic acid, NA-D10, freckle-removing traditional Chinese medicine extracts, lodestone, PHL, rose essential oil and PC-305. The traditional Chinese medicine freckle-removing essence can repair skin damage, such as: sunburn, acne marks, and slight speckle fading.

Description

Traditional Chinese medicine freckle-removing essence and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine skin care, and particularly relates to a traditional Chinese medicine freckle-removing essence and a preparation method thereof.
Background
Plaques are brown spots on the face that are formed as a result of an increase in skin melanin. The spots worsen after exposure to sunlight. Women with menstrual disorders or pregnancy also develop spots. Plaques are diseases which are localized in color change but which belong to the skin class without elevations and depressions. The spots are formed along with age stress, bad living habits and the oxidation of healthy skin cells, the loss of the activity of the cells and the accumulation on the surface of the skin due to the failure of normal metabolism. The common spots include freckle, chloasma, senile plaque, dermal spot, plumbum and mercuric spot, hormone spot, and color-deposited spot. The most common of the young and middle-aged women are chloasma, sunburn and acne marks, which are all caused by acquired factors.
Chloasma is mostly seen in young and middle-aged women, skin lesions are light brown to dark brown patches which are generally symmetrical and in patch shapes, can also be seen in forehead, eyebrow, cheeks, nose, periphery of mouth and the like, have clear boundaries and no subjective symptoms, and the skin lesions are deepened after the sun exposure, and some women suffer from deepened color before menstruation.
Sunburn, as the name suggests, is caused by sun exposure, and therefore occurs well in both sexes of middle-aged people, 40 and 50 years old, but also in early years of 20 and 30 years old. Clinically, sunburn is a brownish black spot focus which is clearly defined in the country and can be from sesame to coin. The good hair parts are the face, the back of the hand, the back, the chest, the upper limbs and the lower limbs, but the focus of the face is larger and more obvious.
Due to excessive secretion of sebaceous glands in the dermis layer of the skin, endocrine disturbance and the like, part of beauty nurses can generate acne on the face in the adolescence stage, the acne belongs to local inflammatory reaction of the skin, and pigmentation, also called acne marks, can be formed on the surface of the skin in the healing process of the acne.
Most Asian women pay high attention to freckle removal, and the traditional Chinese medicine is applied to cosmetics, can protect skin and achieve the effect of skin treatment due to natural non-side effects, and is more and more popular with people who remove freckles.
Patent CN108096147A discloses a preparation method of a traditional Chinese medicine mask for removing freckles, whitening skin, maintaining beauty and keeping young, the traditional Chinese medicines of the preparation method of the traditional Chinese medicine mask comprise: radix pseudostellariae, rhizoma cyperi, scorpion, stiff silkworm, poria cocos, radix angelicae, radix paeoniae rubra, angelica sinensis, cynanchum atratum, beautyberry, ligusticum wallichii, motherwort, szechwan chinaberry fruit, artemisia anomala, ginger juice, radix paeoniae alba, Chinese yam, bighead atractylodes rhizome, astragalus mongholicus, rhizoma typhonii, polygonatum odoratum, almond, ampelopsis japonica, semen coicis, cuttlebone, codonopsis pilosula, angelica sinensis, gypsum, bletilla striata, pearl powder, gardenia, coptis chinensis, radix rehmanniae, salvia miltiorrhiza, scutellaria baicalensis, loofah sponge, stiff silkworm, talc, rhizoma kaempferiae, clove, liquorice, oyster, tribulus terrestris, garden balsam stem, safflower carthamus, borneol, polygonum multiflorum, radix asparagi, ophiopogon root, cortex moutan, ginseng, propolis, deer oil, deer fetus, egg oil, human placenta, dried orange peel, wolfberry, pseudo-ginseng, semen cuscutae, fructus psoraleae, rhizoma nardostachyos, polygala, caulis spatholobi, herba Houttuyniae, herba Saussureae Involueratae, Cordyceps, Ganoderma, herba asari, flos Caryophylli, spina Gleditsiae, herba Patriniae, fructus forsythiae, rhizoma Smilacis Glabrae, and rhizoma paridis. The preparation method of the traditional Chinese medicine mask comprises the following steps: a. grinding the traditional Chinese medicines into 80-120 meshes of fine powder, adding starch and vegetable oil, mixing and sieving to obtain traditional Chinese medicine powder; b. mixing yeast and clear water, standing for 10-30 minutes, pouring into the traditional Chinese medicine powder in the step a, and stirring into thick paste; c. b, putting the paste obtained in the step b at the temperature of 20-40 ℃ for fermentation to 2-3 times of the size of the paste to obtain fermented paste; d. c, adding water into the paste fermented in the step c to adjust the paste to be slightly thicker than the soybean milk, and fermenting for 2 times to obtain 2 times of fermented thin paste; e. and (3) applying oil on the surface of the special die, putting the special die on a furnace for heating, adding the thin paste obtained after 2 times of fermentation, pressing the thin paste obtained after 2 times of fermentation into thin wafers, and taking out the wafers to obtain the traditional Chinese medicine mask. The traditional Chinese medicine mask has a plurality of medicinal tastes, is provided with both animal medicines and plant medicines, contains medicinal materials such as deer oil, deer placenta, human placenta which are not purchased well, and also contains famous and precious medicinal materials such as ginseng, snow lotus herb, cordyceps sinensis and the like, firstly, the medicinal materials in the prescription are not easy to be packed, secondly, the cost is high, the preparation and the use need to be fermented again, and the animal medicines are not easy to be stored after being fermented. The components of the traditional Chinese medicine mask for removing freckles, whitening, beautifying and nourishing the face comprise toxic medicines such as scorpion, stiff silkworm (white stiff silkworm), szechwan chinaberry fruit and asarum, and also some medicines forbidden to be used in skin care products and cosmetics such as angelica dahurica (experimental research easily causes photosensitive reaction), and uncertain factors have potential risks of causing skin problems.
Patent CN105853319A discloses a purslane facial cream for diminishing inflammation, resisting allergy and removing freckles, which comprises the following raw material medicines in parts by weight: 10-50 parts of purslane, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of astragalus membranaceus, 10-20 parts of motherwort, 10-20 parts of centella, 10-20 parts of salvia miltiorrhiza, 10-20 parts of selfheal, 10-20 parts of trichosanthes root, 10-20 parts of safflower, 10-20 parts of radix paeoniae alba, 10-20 parts of bletilla striata, 10-20 parts of mint, 10-20 parts of lithospermum, 10-20 parts of radix ampelopsis, 10-20 parts of radix angelicae, 10-20 parts of geranium, 10-20 parts of calendula, 10-20 parts of angelica sinensis, 10-20 parts of white muscardine silkworm, 10-20 parts of rose and 10-20 parts of stringy stonecrop. The face cream contains 21 traditional Chinese medicines, is complex in formula, contains toxic medicine of stiff silkworm (white stiff silkworm) and banned medicine of angelica dahurica (experimental research easily causes photosensitive reaction), and has potential risk of causing skin problems due to uncertain factors.
Therefore, the research and development of natural freckle-removing products with good safety, obvious freckle-inhibiting effect, good cost performance and convenient preparation and use still belongs to one of the main research directions of the current traditional Chinese medicine cosmetic industry.
Disclosure of Invention
In order to solve the technical problems, the invention provides a traditional Chinese medicine freckle-removing essence and a preparation method thereof.
The invention is realized by the following technical scheme:
the traditional Chinese medicine freckle-removing essence is prepared from the following raw materials in percentage by weight:
Figure BDA0002561762560000021
Figure BDA0002561762560000031
in the traditional Chinese medicine freckle-removing essence, the freckle-removing traditional Chinese medicine extract is prepared from the following raw materials in parts by weight:
1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile.
Preferably, in the traditional Chinese medicine freckle-removing essence, the freckle-removing traditional Chinese medicine extract is prepared from the following raw materials in parts by weight:
5 parts of lithospermum; 5 parts of angelica; 2.5 parts of Pu' er tea; 2.5 parts of rose; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile.
In the freckle-removing traditional Chinese medicine composition, the lithospermum is preferably Sinkiang lithospermum, and the effect of the Sinkiang lithospermum is better due to the special climate of Sinkiang. The angelica is preferably selected from the head of the angelica, the angelica is divided into the head part, the body part and the tail part, the angelica is biased to enrich the blood and promote the blood circulation, the body part enriches the blood, the tail part breaks the blood and the freckle is mainly used for removing the freckle on the face, and the angelica is selected to enhance the efficacy of the head and the face. When the freckle-removing traditional Chinese medicine composition is extracted, the head of the angelica is cut into slices of 1-10mm, so that the effective ingredients are conveniently dissolved out. The rose is preferably Damascus rose buds which belong to the top-grade roses, so that the quality is better and the effect is stronger. Radix Paeoniae alba and rhizoma Ligustici are the traditional Chinese medicines specified in Chinese pharmacopoeia. Chamomile is a common cosmetic raw material. The Pu her tea is selected from Yunnan Qizi cake Pu her.
The preparation method of the traditional Chinese medicine freckle-removing essence comprises the following steps of;
(1) taking 100 parts of 1, 3-butanediol and 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in 1,3 butanediol, stirring for 3 min every 4 hr, soaking for 120 hr, heating the mixed solution of 1,3 butanediol to 50 deg.C, maintaining for 3 min, and filtering to obtain 1,3 butanediol extract. The stirring speed is 50-60 r/min.
In the freckle-removing essence, AVC is an acryloyl dimethyl ammonium taurate/VP copolymer; the NA-D10 is a mixture of soluble proteoglycan and butanediol, and the weight ratio of the soluble proteoglycan to the butanediol is 3: 2; the PHL is a mixture of 1, 2-hexanediol, caprylyl hydroximic acid and 1, 3-propylene glycol, and the weight ratio of the 1, 2-hexanediol, the caprylyl hydroximic acid and the 1, 3-propylene glycol is 3: 2: 2; the PC-305 is a common solubilizer for cosmetics and can be obtained commercially.
All ratios referred to in this application are by weight.
The preparation method of the freckle-removing essence comprises the following steps:
(1) adding water, AVC, betaine, allantoin, transparent xanthan gum, glycerol and small molecular hyaluronic acid into an emulsifying pot, stirring and dispersing completely, heating to 90 ℃, and sterilizing at constant temperature for 15 minutes;
(2) cooling after complete sterilization;
(3) cooling to 45 deg.C, adding NA-D10, alcohol-soluble Chinese medicinal oil, water-locking magnet, and PHL;
(4) adding the premixed rose essential oil and PC-305, and stirring uniformly;
(5) reducing the temperature to 38 ℃, filtering and discharging to obtain the product.
The essence comprises the following components:
Figure BDA0002561762560000041
the invention has the beneficial effects that:
(1) the prescription of the freckle-removing traditional Chinese medicine composition takes the alkanna tinctoria root as a monarch, and the alkanna tinctoria root is cool and hot in blood and can promote blood generation, and has the effects of relieving fever, diminishing inflammation, enriching blood and sterilizing. The angelica is taken as the minister, and the angelica has the functions of nourishing blood, invigorating blood circulation and moistening skin, has obvious cleaning, pus discharge and repairing functions when being used together with the alkanna tinctoria root, and promotes the formation of granulation. The rose flower has the effects of promoting qi circulation, relieving depression, harmonizing blood and relieving pain, is commonly used for calming the liver, nourishing the stomach and promoting blood circulation by ancient people, is researched by modern times, has the functions of moistening skin, promoting cell regeneration and fading fine wrinkles by external application, has pleasant fragrance, and is an assistant in the formula. White peony root, Chinese ligusticum rhizome, chamomile and Pu' er tea have synergistic effect, and can nourish blood, whiten skin, detoxify, diminish inflammation, promote aging and make skin glow.
(2) The freckle-removing traditional Chinese medicine composition is prepared by adding rose flowers on the basis of basic formulas of lithospermum and angelica sinensis in Mingdingcheng Chenkuang, and then adding white paeony root, ligusticum, chamomile and Pu' er, has simple medicinal taste, is researched and practiced in a large number of aspects of effectiveness, safety, color and smell, and is a product which can be safely used for a long time and has the effects of whitening, detoxifying, diminishing inflammation, removing freckles and promoting skin tissue regeneration.
(3) The extract soaked in the traditional Chinese medicine according to the proportion is added into cosmetics, and can repair skin damage, such as: sunburn, acne marks, slight speckle fading, skin-friendly feeling of the cosmetic and smoothness of the cosmetic.
(4) In the prior art, most of the traditional Chinese medicines are extracted from single Chinese medicines, and the mixed extraction in the proportion has the advantage that the drug effects of the traditional Chinese medicines are related through the proportion, so that the drug effects are more obvious.
Detailed Description
The present invention will be further described with reference to specific examples so that those skilled in the art may better understand the present invention, but the present invention is not limited thereto.
In the embodiment of the invention, the AVC is purchased from Shanghai New trade company, Inc.; the betaine is purchased from Shanghai New trade, Inc.; the allantoin was purchased from Shanghai New trade, Inc.; the transparent xanthan gum is purchased from Shanghai Daoshi New trade company, Inc.; the glycerol was purchased from Shanghai New trade, Inc.; the small molecule hyaluronic acid is purchased from Shanghai's common technical center; the NA-D10 was purchased from Tianjin Soddy, Inc.; the water-locking magnet is purchased from Shanghai Luya biotechnology limited; the PHL was purchased from Shanghai Haoyun trade company, Inc.; the rose essential oil is purchased from Sichuan Chinese rose paddy; the PC-305 was purchased from New trade, Inc. of Shanghai.
Example 1
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
5 parts of Sinkiang arnebia root; 5 parts of angelica sinensis head slices; 2.5 parts of Pu' er tea; 2.5 parts of Damascus rose buds; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile.
The preparation method of the freckle-removing traditional Chinese medicine composition comprises the following steps:
(1) taking 100 parts of 1, 3-butanediol and 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in 1, 3-butanediol, stirring every 4 hr for 3 min, soaking for 120 hr, heating the mixed liquid of 1, 3-butanediol and Chinese medicinal materials to 50 deg.C, maintaining for 3 min, and filtering to obtain 1, 3-butanediol extract. The stirring speed is 50-60 r/min.
Example 2
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
1 part of Sinkiang arnebia root; 1 part of angelica sinensis head slice; 1 part of Pu' er tea; 1 part of Damascus rose buds; 1 part of white peony root; 1 part of ligusticum and 1 part of chamomile.
The preparation method is the same as example 1.
Example 3
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
10 parts of Sinkiang lithospermum; 10 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 5 parts of white peony root; 5 parts of ligusticum and 5 parts of chamomile. The preparation method is the same as example 1.
Example 4
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
1 part of Sinkiang arnebia root; 10 parts of angelica sinensis head slices; 1 part of Pu' er tea; 5 parts of Damascus rose buds; 1 part of white peony root; 5 parts of ligusticum and 1 part of chamomile.
Example 5
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
10 parts of Sinkiang lithospermum; 1 part of angelica sinensis head slice; 5 parts of Pu' er tea; 1 part of Damascus rose buds; 5 parts of white peony root; 1 part of ligusticum and 5 parts of chamomile. The preparation method is the same as example 1.
Example 6
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
8 parts of Sinkiang arnebia root; 8 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 2 parts of white peony root; 2 parts of ligusticum and 2 parts of chamomile. The preparation method is the same as example 1.
Example 7
A freckle-removing traditional Chinese medicine composition used in freckle-removing essence is prepared from the following raw materials in parts by weight:
5 parts of Sinkiang arnebia root; 5 parts of angelica sinensis head slices; 5 parts of Pu' er tea; 5 parts of Damascus rose buds; 5 parts of white peony root; 2 parts of ligusticum and 2 parts of chamomile. The preparation method is the same as example 1.
Example 8
The freckle-removing essence is prepared from the following raw materials in percentage by weight:
Figure BDA0002561762560000061
Figure BDA0002561762560000071
the preparation method of the freckle-removing essence comprises the following steps:
(1) adding water, AVC, betaine, allantoin, transparent xanthan gum, glycerol and small molecular hyaluronic acid into an emulsifying pot, stirring and dispersing completely, heating to 90 ℃, and sterilizing at constant temperature for 15 minutes;
(2) cooling after complete sterilization;
(3) cooling to 45 deg.C, adding NA-D10, alcohol-soluble Chinese medicinal oil, water-locking magnet, and PHL;
(4) adding the premixed rose essential oil and PC-305, and stirring uniformly;
(5) reducing the temperature to 38 ℃, filtering and discharging to obtain the product.
The traditional Chinese medicine freckle-removing essence disclosed by the invention is tested and detailed as follows
The purpose is as follows: the formulations were tested for effectiveness.
The testing process comprises the following steps: from 1/3/2020, the duration is 4 weeks, and the end of 28/3/2020, all tested persons are volunteers, and teachers, clerks, general workers in workshops, bank counter workers, finance workers, community workers and the like are in occupations, and the tested group volunteers use the traditional Chinese medicine freckle removing essence and the control group volunteers use common essence.
First, front-end data packet: (the formula proportion of the freckle-removing traditional Chinese medicine composition in the skin care product used by the front-end data group is 5 parts of Sinkiang arnebia root, 5 parts of Chinese angelica root head slices, 2.5 parts of Pu' er tea, 2.5 parts of damascus rose buds, 2.5 parts of white paeony root, 2.5 parts of Chinese ligusticum rhizome and 2.5 parts of chamomile, and the preparation method is the same as the embodiment 8)
A first group: mild plaques, age 30-50 women 10
Second group: sunburn, age 30-50 women 10 people
Third group: acne mark, age 30-50 female 10 people
Fourth group, control group: female 10 people with slight spot or sunburn or acne mark
Group/variation First week Second week The third week The fourth side Remarks/conclusions
First group Without change Without change Slightly bland in color Become remarkably light Obviously improve
Second group Without change Without change Slight improvement Obviously improve Obviously improve
Third group The change is not obvious Become light Become light Become remarkably light Obviously improve
Fourth group Without change Without change Without change Without change Without change
And (4) conclusion: after the application for 4 weeks, the test volunteers have obviously improved spots, acne marks and sunburn, and the control group has no change.
Second, median data grouping: (the prescription proportion of the freckle-removing traditional Chinese medicine composition in the skin care product used by the middle-end data group is 8 parts of Sinkiang arnebia root, 8 parts of Chinese angelica root head slice, 5 parts of Pu' er tea, 5 parts of damascus rose bud, 2 parts of white paeony root, 2 parts of Chinese ligusticum rhizome and 2 parts of chamomile, and the preparation method is the same as the embodiment 8)
A first group: mild plaques, age 30-50 women 10
Second group: sunburn, age 30-50 women 10 people
Third group: acne mark, age 30-50 female 10 people
Fourth group, control group: slight freckle, sunburn and acne mark in 10 women
Group/variation First week Second week The third week The fourth side Remarks/conclusions
First group Without change Slightly bland in color Slightly bland in color Become light Slightly improved
Second group Without change Without change Slight improvement Become light Slightly improved
Third group The change is not obvious Become light Become light Become remarkably light Obviously improve
Fourth group Without change Without change Without change Without change Without change
And (4) conclusion: after the test composition is continuously used for 4 weeks, the spots and sunburn of the volunteers in the test group are slightly improved, the acne marks are obviously improved, and the control group is unchanged.
Third, back-end data grouping: (the formula proportion of the freckle-removing traditional Chinese medicine composition in the skin care product used by the back end data group is 5 parts of Sinkiang arnebia root, 5 parts of Chinese angelica head slices, 5 parts of Pu' er tea, 5 parts of damascus rose buds, 5 parts of white paeony root, 2 parts of Chinese ligusticum rhizome and 2 parts of chamomile, and the preparation method is the same as that of the example 8)
A first group: mild plaques, age 30-50 women 10
Second group: sunburn, age 30-50 women 10 people
Third group: acne mark, age 30-50 female 10 people
Fourth group, control group: slight freckle, sunburn and acne mark in 10 women
Group/variation First week Second week The third week The fourth side Remarks/conclusions
First group Without change Slightly bland in color Slightly bland in color Become remarkably light Obviously improve
Second group Without change Slightly bland in color Slight improvement Obviously improve Obviously improve
Third group The change is not obvious Become light Become light Become remarkably light Obviously improve
Fourth group Without change Without change Without change Without change Without change
And (4) conclusion: after the application for 4 weeks, the test volunteers have obviously improved spots, acne marks and sunburn, and the control group has no change.
To summarize: the traditional Chinese medicine freckle-removing essence added with the freckle-removing traditional Chinese medicine composition in different proportions is used for 4 weeks, so that freckles, acne marks and sunburn are obviously improved, and a control group is unchanged. The relative dosage of Pu' er tea, rose and white paeony root relative to the lithospermum and the angelica can be increased, so that the treatment effect of sunburn can be improved.

Claims (9)

1. The traditional Chinese medicine freckle-removing essence is prepared from the following raw materials in percentage by weight:
Figure FDA0002561762550000011
2. the traditional Chinese medicine freckle-removing essence according to claim 1, wherein the freckle-removing traditional Chinese medicine extract is prepared from the following raw materials in parts by weight:
1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile.
3. The traditional Chinese medicine freckle-removing essence according to claim 2, wherein the freckle-removing traditional Chinese medicine extract is prepared from the following raw materials in parts by weight:
5 parts of lithospermum; 5 parts of angelica; 2.5 parts of Pu' er tea; 2.5 parts of rose; 2.5 parts of white paeony root; 2.5 parts of ligusticum and 2.5 parts of chamomile.
4. The traditional Chinese medicine freckle-removing essence according to claim 2 or 3, wherein the preparation method of the freckle-removing traditional Chinese medicine extract comprises the following steps of;
(1) taking 100 parts of 1, 3-butanediol and 1-10 parts of lithospermum; 1-10 parts of angelica; 1-5 parts of Pu' er tea; 1-5 parts of rose; 1-5 parts of white peony root; 1-5 parts of ligusticum and 1-5 parts of chamomile;
(2) soaking radix Arnebiae, radix Angelicae sinensis, Pu her, flos Rosae Rugosae, radix Paeoniae alba, rhizoma Ligustici, and flos Matricariae Chamomillae in 1,3 butanediol, stirring for 3 min every 4 hr, soaking for 120 hr, heating the mixed solution of 1,3 butanediol to 50 deg.C, maintaining for 3 min, and filtering to obtain 1,3 butanediol extract.
5. The traditional Chinese medicine freckle-removing essence of claim 1, wherein AVC is an ammonium acryloyldimethyl taurate/VP copolymer.
6. The traditional Chinese medicine freckle-removing essence according to claim 1, wherein the NA-D10 is a mixture of soluble proteoglycan and butanediol, and the weight ratio of the soluble proteoglycan to the butanediol is 3: 2.
7. the essence of claim 1, wherein the PHL is a mixture of 1, 2-hexanediol, caprylhydroxamic acid, and 1, 3-propanediol, and the weight ratio of 1, 2-hexanediol, caprylhydroxamic acid, and 1, 3-propanediol is 3: 2: 2.
8. the essence of claim 1, wherein the PC-305 is a common cosmetic solubilizer and is commercially available.
9. The preparation method of the traditional Chinese medicine freckle-removing essence is characterized by comprising the following steps of:
(1) adding water, AVC, betaine, allantoin, transparent xanthan gum, glycerol and small molecular hyaluronic acid into an emulsifying pot, stirring and dispersing completely, heating to 90 ℃, and sterilizing at constant temperature for 15 minutes;
(2) cooling after complete sterilization;
(3) cooling to 45 deg.C, adding NA-D10, alcohol-soluble Chinese medicinal oil, water-locking magnet, and PHL;
(4) adding the premixed rose essential oil and PC-305, and stirring uniformly;
(5) reducing the temperature to 38 ℃, filtering and discharging to obtain the product.
CN202010617150.2A 2020-06-30 2020-06-30 Traditional Chinese medicine freckle-removing essence and preparation method thereof Pending CN111658558A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010617150.2A CN111658558A (en) 2020-06-30 2020-06-30 Traditional Chinese medicine freckle-removing essence and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010617150.2A CN111658558A (en) 2020-06-30 2020-06-30 Traditional Chinese medicine freckle-removing essence and preparation method thereof

Publications (1)

Publication Number Publication Date
CN111658558A true CN111658558A (en) 2020-09-15

Family

ID=72390472

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010617150.2A Pending CN111658558A (en) 2020-06-30 2020-06-30 Traditional Chinese medicine freckle-removing essence and preparation method thereof

Country Status (1)

Country Link
CN (1) CN111658558A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112107501A (en) * 2020-10-27 2020-12-22 苏州家和蚕业生物科技有限公司 Preparation method of fibroin mask solution
CN112957271A (en) * 2021-02-26 2021-06-15 山东科思达美生物科技有限公司 Polypeptide composition for quickly removing wrinkles and resisting aging

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102293733A (en) * 2011-08-25 2011-12-28 北京药谷传奇医药科技开发有限公司 Overall whitening and speckle removal skin care product
CN103830152A (en) * 2014-03-14 2014-06-04 集安五味堂生物科技有限公司 Cosmetic composition and essence with skin whitening function
CN105168039A (en) * 2015-08-14 2015-12-23 北京兰厚化妆品有限责任公司 Chinese herbal medicine whitening and skin tendering base solution and preparation method therefor
CN109276456A (en) * 2018-11-09 2019-01-29 东阿阿胶股份有限公司 A kind of donkey milk facial mask and its preparation process with skin whitening, moisturizing effect

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102293733A (en) * 2011-08-25 2011-12-28 北京药谷传奇医药科技开发有限公司 Overall whitening and speckle removal skin care product
CN103830152A (en) * 2014-03-14 2014-06-04 集安五味堂生物科技有限公司 Cosmetic composition and essence with skin whitening function
CN105168039A (en) * 2015-08-14 2015-12-23 北京兰厚化妆品有限责任公司 Chinese herbal medicine whitening and skin tendering base solution and preparation method therefor
CN109276456A (en) * 2018-11-09 2019-01-29 东阿阿胶股份有限公司 A kind of donkey milk facial mask and its preparation process with skin whitening, moisturizing effect

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张子茜: ""消斑霜的临床应用"", 《中医中药》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112107501A (en) * 2020-10-27 2020-12-22 苏州家和蚕业生物科技有限公司 Preparation method of fibroin mask solution
WO2022088285A1 (en) * 2020-10-27 2022-05-05 苏州家和蚕业生物科技有限公司 Preparation method for silk fibroin facial mask solution
CN112957271A (en) * 2021-02-26 2021-06-15 山东科思达美生物科技有限公司 Polypeptide composition for quickly removing wrinkles and resisting aging

Similar Documents

Publication Publication Date Title
CN105497246B (en) Traditional Chinese medicine material for treating whelk and preparation method of traditional Chinese medicine
CN102266445B (en) Eye protection Chinese medicinal composition with health care and treatment effects
CN111714425B (en) Shampoo composition for improving scalp and hair condition
CN109568556B (en) Traditional Chinese medicine composition and shampoo for treating alopecia
CN104784507A (en) Traditional Chinese medicine composition with multiple cosmetic effects and application
CN111529477A (en) Composition for caring hair, and preparation and application thereof
CN113750015A (en) Acne removing composition with acne mark removing and scar removing effects and preparation method thereof
CN110638954A (en) Whitening and freckle removing composition and preparation method thereof
CN105878126A (en) Traditional Chinese medicine mask including caulis dendrobii
CN110755358A (en) Five-nourishing angelica-source Chinese herbal medicine hair nourishing composition and preparation thereof
CN111658558A (en) Traditional Chinese medicine freckle-removing essence and preparation method thereof
CN110664643A (en) Polypeptide essence with multiple-effect whitening effect and preparation method thereof
CN114533625A (en) Anti-hair-loss hair-growing liquid and preparation method thereof
CN111840197B (en) A traditional Chinese medicine-based whitening anti-inflammatory moisturizing facial mask containing radix Codonopsis and radix astragali, and its preparation method
CN112773748A (en) Traditional Chinese medicine shampoo for treating seborrheic alopecia and application thereof
CN112315871A (en) Traditional Chinese medicine shampoo for scalp and hair care and preparation method thereof
CN115006336B (en) Plant shampoo capable of preventing hair loss, strengthening hair, removing dandruff and relieving itching and preparation method thereof
CN111759919A (en) Freckle-removing traditional Chinese medicine composition and preparation method thereof, freckle-removing traditional Chinese medicine face cream and preparation method thereof
CN106726993A (en) Chinese medicine hair cream and preparation method
CN111568831B (en) Composition of Chinese herbal medicine extract for skin cosmetics and preparation method thereof
CN102133167A (en) Freckle removing facial mask made of traditional Chinese medicine and preparation process thereof
CN112999306A (en) Traditional Chinese medicine composition for whitening skin and removing freckles and application thereof
CN112386560A (en) A skin caring and speckle removing product containing Chinese medicinal components, and its preparation method
CN112121135A (en) Traditional Chinese medicine hair conditioner for scalp and hair care and preparation method thereof
CN112545969A (en) Compound traditional Chinese medicine mask for moisturizing and removing acne and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20200915

RJ01 Rejection of invention patent application after publication