CN102335376B - Compound preparation with stronger antibacterial and itch relieving functions of plant extract - Google Patents
Compound preparation with stronger antibacterial and itch relieving functions of plant extract Download PDFInfo
- Publication number
- CN102335376B CN102335376B CN2011102587990A CN201110258799A CN102335376B CN 102335376 B CN102335376 B CN 102335376B CN 2011102587990 A CN2011102587990 A CN 2011102587990A CN 201110258799 A CN201110258799 A CN 201110258799A CN 102335376 B CN102335376 B CN 102335376B
- Authority
- CN
- China
- Prior art keywords
- dermatophyte
- killing agent
- herba
- filling
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000003251 Pruritus Diseases 0.000 title claims abstract description 7
- 238000002360 preparation method Methods 0.000 title description 4
- 150000001875 compounds Chemical class 0.000 title description 3
- 230000000844 anti-bacterial effect Effects 0.000 title description 2
- 239000000419 plant extract Substances 0.000 title description 2
- 239000003814 drug Substances 0.000 claims abstract description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims abstract description 3
- 230000001954 sterilising effect Effects 0.000 claims description 6
- 230000003385 bacteriostatic effect Effects 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- 238000012856 packing Methods 0.000 claims description 3
- 241000218176 Corydalis Species 0.000 claims description 2
- 241000628997 Flos Species 0.000 claims description 2
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 2
- 239000009670 cang er zi wan Substances 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 claims description 2
- 230000006837 decompression Effects 0.000 claims description 2
- 230000003203 everyday effect Effects 0.000 claims description 2
- 210000004907 gland Anatomy 0.000 claims description 2
- 238000001556 precipitation Methods 0.000 claims description 2
- 239000009806 pulsatillae Substances 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 229940040145 liniment Drugs 0.000 claims 2
- 239000000865 liniment Substances 0.000 claims 2
- 229940126678 chinese medicines Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 229940079593 drug Drugs 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 244000052616 bacterial pathogen Species 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000005855 radiation Effects 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 230000001988 toxicity Effects 0.000 abstract description 2
- 231100000419 toxicity Toxicity 0.000 abstract description 2
- 241001480043 Arthrodermataceae Species 0.000 abstract 5
- 239000003139 biocide Substances 0.000 abstract 5
- 230000037304 dermatophytes Effects 0.000 abstract 5
- 239000011521 glass Substances 0.000 abstract 2
- 244000307697 Agrimonia eupatoria Species 0.000 abstract 1
- 241000049624 Alisma plantago-aquatica subsp. orientale Species 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 235000017965 Asarum canadense Nutrition 0.000 abstract 1
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 235000000385 Costus speciosus Nutrition 0.000 abstract 1
- 240000007371 Cuscuta campestris Species 0.000 abstract 1
- 244000085625 Equisetum Species 0.000 abstract 1
- 241000221079 Euphorbia <genus> Species 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 241001522129 Pinellia Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 241000206469 Pulsatilla Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 241000606265 Valeriana jatamansi Species 0.000 abstract 1
- 244000067505 Xanthium strumarium Species 0.000 abstract 1
- 235000014687 Zingiber zerumbet Nutrition 0.000 abstract 1
- 235000000125 common agrimony Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000001139 anti-pruritic effect Effects 0.000 description 2
- 239000003908 antipruritic agent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002070 germicidal effect Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 206010012504 Dermatophytosis Diseases 0.000 description 1
- 241001460074 Microsporum distortum Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 102000011759 adducin Human genes 0.000 description 1
- 108010076723 adducin Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a dermatophyte killing agent, which consists of 20 kinds of medicaments, namely Chinese pulsatilla root, kenchor, angelica dahurica, corydlis bungeana, cocklebur fruit, humifuse euphorbia herb, dried orange peel, radix bupleuri, pinellia tuber, spica prunellae, hairyvein agrimony, oriental waterplantain rhizome, rhizome chuanxiong, tuckahoe, bletilla striata, dandelion, field dodder, equisetum, manchurian wildginger and honeysuckle. The dermatophyte killing agent is prepared by the following steps of: respectively taking 200g of dried product of each component and crushing; sieving dried products with a sieve with 120 meshes; respectively filling the dried products into a glass bottle with 3000ml; adding 2000ml of 95 percent edible alcohol and soaking for 3-5 days; fully stirring for 3-5 times each day; settling and siphoning; filling the mixture into a filling bottle with 20000ml and upper and lower mouths; carrying out high-position pressure reduction; filtering by using a No.6 vertical soluble funnel; sub-filling 100ml of solution in a cleaned and sterilized glass bottle in an aseptic room; and capping and packaging to obtain the dermatophyte killing agent. The dermatophyte killing agent can be and effectively and widely applied to treating inflammation, pruritus and other symptoms caused by pathogenic bacteria intrusion to human skin with unique efficacy and can be used for absorbing ultraviolet rays of sunlight to prevent the skin from being injured by sunlight radiation; and the dermatophyte killing agent is a current drug of choice with low dosage, small toxicity, small side effect and high curative effect.
Description
Affiliated field
This bacterio static itching-relieving compound preparation is a kind of multiple Chinese herbal medicine and clinically known dermopathic elimination agent that is used for the treatment of through using for many years of merging, and antiinflammatory, heat clearing away, pain relieving, the disease such as antipruritic are had unique effects.
Background technology
At present, known germicide for skin contains the zest medicines such as salicylic acid of hormone chemical more, can not continue and is widely used, and particularly is not suitable for infant.
Summary of the invention
The present invention in conjunction with clinical medicinal, filters out 20 flavors from numerous Chinese medicine on the basis of known pharmaceutical chemistry structure pharmacology, extract the dermatophytosis elimination agent that can overcome existing germicide for skin deficiency after the tight prescription of examining mixes, purifies.
The technical scheme that the present invention overcomes known for skin antibacterial deficiency is: the present invention is comprised of the Radix Pulsatillae, husky Rhizoma Zingiberis Recens, the Radix Angelicae Dahuricae, Herba Corydalis Bungeanae, Fructus Xanthii, Herba Euphorbiae Humifusae, Pericarpium Citri Reticulatae, Radix Bupleuri, the Rhizoma Pinelliae, Spica Prunellae, Herba Agrimoniae, Rhizoma Alismatis, Rhizoma Chuanxiong, Poria, Pseudobulbus Bletillae (Rhizoma Bletillae) (Pseudobulbus Bletillae (Rhizoma Bletillae)), Herba Taraxaci, Semen Cuscutae (field dobber), Radix Scorzonerae Albicaulis (Radix Scorzonerae Albicaulis), Herba Asari, Flos Lonicerae 20 herbal medicine dry products, Each performs its own functions for each medicine, cooperatively interact, thereby reach the purpose that solves skin antiinflammatory, heat clearing away, pain relieving, the effect such as antipruritic; The present invention is pure Chinese medicinal preparation in addition, does not contain dripping of irritant drugs, can directly apply to the human body skin surface in extensive and long-term ground.In June, 2011, the detection through Ministry of Public Health skin sterilizing product standard is pressed by clinical laboratory of Yunnan Province Centre for Disease Control of Department of Public Health has drawn this product indices and met relevant regulations, but sterilizing rate reaches 100% conclusion.
The invention has the beneficial effects as follows: consumption is little, toxicity is little, side effect is little, can not only apply to effectively widely to treat the symptoms such as inflammation that human body skin causes because of the pathogenic bacterium invasion, pruritus, and can absorb UV sunlight, make skin avoid the damage of solar radiation.Simultaneously, processing technology of the present invention is easy, and is with low cost, and DEVELOPMENT PROSPECT is wide.
The specific embodiment
Got in each 200g → pulverizing of each medicine dry product → mistake 120 mesh sieves → be respectively charged into 3000ml vial → add 95% edible ethanol 2000ml → immersion 3-5 days, fully stir 3-5 time every day, in the fill upper and lower opening bottle of the precipitation siphon → 20000ml that packs into → high-order decompression hang down for → No. 6 molten funnels filter → in sterilizing room packing 100ml solution in the vial that cleaning and sterilizing is crossed → gland → finished product.
Claims (2)
1. the liniment of a bacterio static itching-relieving, it is characterized in that: made by the Radix Pulsatillae, husky Rhizoma Zingiberis Recens, the Radix Angelicae Dahuricae, Herba Corydalis Bungeanae, Fructus Xanthii, Herba Euphorbiae Humifusae, Pericarpium Citri Reticulatae, Radix Bupleuri, the Rhizoma Pinelliae, Spica Prunellae, Herba Agrimoniae, Rhizoma Alismatis, Rhizoma Chuanxiong, Poria, Pseudobulbus Bletillae (Rhizoma Bletillae), Herba Taraxaci, Semen Cuscutae, Radix Scorzonerae Albicaulis, Herba Asari, Flos Lonicerae 20 flavor Chinese medicines, every flavor Chinese medicine is got identical weight part, prepares with alcohol-pickled.
2. the liniment of a kind of bacterio static itching-relieving as claimed in claim 1 is characterized in that: get above-mentioned 20 each 200g of flavor Chinese medicine and pulverize, cross 120 mesh sieves, be respectively charged in the 3000ml vial, the edible ethanol 2000ml of adding 95% soaked 3-5 days, and fully stir 3-5 time every day, the precipitation siphon, pack in the fill upper and lower opening bottle of 20000ml, high-order decompression, No. 6 the molten funnel that hangs down filters, packing 100ml solution is in the vial that cleaning and sterilizing is crossed in sterilizing room, and the gland packing forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102587990A CN102335376B (en) | 2011-08-28 | 2011-08-28 | Compound preparation with stronger antibacterial and itch relieving functions of plant extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102587990A CN102335376B (en) | 2011-08-28 | 2011-08-28 | Compound preparation with stronger antibacterial and itch relieving functions of plant extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102335376A CN102335376A (en) | 2012-02-01 |
| CN102335376B true CN102335376B (en) | 2013-04-03 |
Family
ID=45511476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102587990A Expired - Fee Related CN102335376B (en) | 2011-08-28 | 2011-08-28 | Compound preparation with stronger antibacterial and itch relieving functions of plant extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102335376B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103495095B (en) * | 2013-08-20 | 2015-04-22 | 许其树 | Traditional Chinese medicine external preparation for treating wounds due to noxious heat |
| CN103479981B (en) * | 2013-09-22 | 2015-04-22 | 王贵胜 | Plaster for treating sore and furuncle and innominate toxic swelling |
| CN110693932A (en) * | 2019-10-15 | 2020-01-17 | 段凌升 | Preparation method of three-worm folium artemisiae argyi charcoal powder anti-inflammatory drug |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1709380A (en) * | 2005-06-03 | 2005-12-21 | 季荣生 | Bacterio static itching-relieving liquid and production method |
| CN101502480A (en) * | 2009-02-19 | 2009-08-12 | 南方李锦记有限公司 | Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies |
-
2011
- 2011-08-28 CN CN2011102587990A patent/CN102335376B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1709380A (en) * | 2005-06-03 | 2005-12-21 | 季荣生 | Bacterio static itching-relieving liquid and production method |
| CN101502480A (en) * | 2009-02-19 | 2009-08-12 | 南方李锦记有限公司 | Chinese herbal medicine composition with bacteriostatic, anti-dandruff and itching-relieving efficacies |
Non-Patent Citations (3)
| Title |
|---|
| 中药复方制剂抗真菌的实验研究进展;陶茂灿等;《浙江临床医学》;20081125;第10卷(第11期);1506-1508 * |
| 刘仲霞等.一种纯中药洗液杀(抑)菌效果观察.《中国消毒学杂志》.2008,第25卷(第6期),621-623. * |
| 陶茂灿等.中药复方制剂抗真菌的实验研究进展.《浙江临床医学》.2008,第10卷(第11期),1506-1508. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102335376A (en) | 2012-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130403 Termination date: 20130828 |